Denis McCann

1.8k total citations
26 papers, 826 citations indexed

About

Denis McCann is a scholar working on Molecular Biology, Pharmacology and Oncology. According to data from OpenAlex, Denis McCann has authored 26 papers receiving a total of 826 indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 11 papers in Pharmacology and 7 papers in Oncology. Recurrent topics in Denis McCann's work include Pharmacogenetics and Drug Metabolism (8 papers), Drug Transport and Resistance Mechanisms (5 papers) and PI3K/AKT/mTOR signaling in cancer (4 papers). Denis McCann is often cited by papers focused on Pharmacogenetics and Drug Metabolism (8 papers), Drug Transport and Resistance Mechanisms (5 papers) and PI3K/AKT/mTOR signaling in cancer (4 papers). Denis McCann collaborates with scholars based in United States, Canada and Czechia. Denis McCann's co-authors include Hongyu Li, Karen Huss, Laura J. Bloem, James R. Henry, Weiying Li, Yan Zhai, Sheng‐Bin Peng, Genshi Zhao, Zhaogen Chen and Mohammad Zia‐Ebrahimi and has published in prestigious journals such as Journal of Biological Chemistry, Biochemistry and Cancer Research.

In The Last Decade

Denis McCann

25 papers receiving 810 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Denis McCann United States	15	566	149	109	85	71	26	826
Pamela K. Smitherman United States	18	652 1.2×	327 2.2×	93 0.9×	67 0.8×	52 0.7×	20	1.0k
Tanya Coleman United Kingdom	17	589 1.0×	282 1.9×	115 1.1×	147 1.7×	36 0.5×	28	1.1k
Kai Hung Tiong Malaysia	12	405 0.7×	169 1.1×	141 1.3×	43 0.5×	45 0.6×	18	680
Yoshiki Amuro Japan	17	341 0.6×	222 1.5×	61 0.6×	44 0.5×	51 0.7×	52	735
Jill Chrencik United States	14	629 1.1×	274 1.8×	142 1.3×	83 1.0×	87 1.2×	18	1.1k
Mariagrazia Distefano Italy	14	374 0.7×	265 1.8×	70 0.6×	96 1.1×	100 1.4×	20	746
Emile G. Plise United States	17	493 0.9×	312 2.1×	115 1.1×	77 0.9×	42 0.6×	39	876
Gang Hu China	16	769 1.4×	169 1.1×	41 0.4×	67 0.8×	60 0.8×	24	1.0k
Paresh Thakker United States	15	310 0.5×	120 0.8×	37 0.3×	133 1.6×	70 1.0×	25	918
Hong Lou United States	15	356 0.6×	287 1.9×	47 0.4×	47 0.6×	86 1.2×	31	857

Countries citing papers authored by Denis McCann

Since Specialization

Citations

This map shows the geographic impact of Denis McCann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Denis McCann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Denis McCann more than expected).

Fields of papers citing papers by Denis McCann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Denis McCann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Denis McCann. The network helps show where Denis McCann may publish in the future.

Co-authorship network of co-authors of Denis McCann

This figure shows the co-authorship network connecting the top 25 collaborators of Denis McCann. A scholar is included among the top collaborators of Denis McCann based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Denis McCann. Denis McCann is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Thirunavukkarasu, Kannan, Bo Tan, Craig Swearingen, et al.. (2016). Pharmacological Characterization of a Potent Inhibitor of Autotaxin in Animal Models of Inflammatory Bowel Disease and Multiple Sclerosis. Journal of Pharmacology and Experimental Therapeutics. 359(1). 207–214. 25 indexed citations

Jones, Spencer B., Lance A. Pfeifer, Thomas J. Bleisch, et al.. (2016). Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design. ACS Medicinal Chemistry Letters. 7(9). 857–861. 39 indexed citations

Zamek‐Gliszczynski, Maciej J., Trent L. Abraham, Palaniappan Kulanthaivel, et al.. (2013). Pharmacokinetics, Metabolism, and Excretion of the Glycogen Synthase Kinase-3 Inhibitor LY2090314 in Rats, Dogs, and Humans: A Case Study in Rapid Clearance by Extensive Metabolism with Low Circulating Metabolite Exposure. Drug Metabolism and Disposition. 41(4). 714–726. 36 indexed citations

Burkholder, Timothy P., James R. Henry, David Mendel, et al.. (2011). Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model. Investigational New Drugs. 30(3). 936–949. 16 indexed citations

Konicek, Bruce W., Jennifer R. Stephens, Ann M. McNulty, et al.. (2011). Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases. Cancer Research. 71(5). 1849–1857. 159 indexed citations

Farr, Tracy D., H Carswell, Denis McCann, et al.. (2008). The Selective Oestrogen Receptor Modulator, LY362321, is Not Neuroprotective in a Rat Model of Transient Focal Ischaemia. Journal of Neuroendocrinology. 20(3). 366–374. 6 indexed citations

Li, Hongyu, William T. McMillen, Denis McCann, et al.. (2008). Optimization of a Dihydropyrrolopyrazole Series of Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors: Discovery of an Orally Bioavailable Transforming Growth Factor-β Receptor Type I Inhibitor as Antitumor Agent. Journal of Medicinal Chemistry. 51(7). 2302–2306. 50 indexed citations

Geiser, Andrew G., Conrad W. Hummel, Michael W. Draper, et al.. (2005). A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation. Endocrinology. 146(10). 4524–4535. 42 indexed citations

Hummel, Conrad W., Andrew G. Geiser, Henry U. Bryant, et al.. (2005). A Selective Estrogen Receptor Modulator Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats. Journal of Medicinal Chemistry. 48(22). 6772–6775. 43 indexed citations

10.

Bramlett, Kelli, Chahrzad Montrose, Patricia Foxworthy, et al.. (2003). A Chemical Switch Regulates Fibrate Specificity for Peroxisome Proliferator-activated Receptor α (PPARα) VersusLiver X Receptor. Journal of Biological Chemistry. 278(4). 2403–2410. 54 indexed citations

11.

Vashishtha, Sarvesh C., et al.. (2002). Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships. Drug Metabolism and Disposition. 30(10). 1070–1076. 20 indexed citations

12.

Vashishtha, Sarvesh C., Edward M. Hawes, G. McKay, & Denis McCann. (2001). Quaternary ammonium-linked glucuronidation of 1-substituted imidazoles: studies of human UDP-glucuronosyltransferases involved and substrate specificities.. PubMed. 29(10). 1290–5. 18 indexed citations

13.

Chen, Chuan, et al.. (2000). Effects of clofibrate and indocyanine green on the hepatobiliary disposition of acetaminophen and its metabolites in male CD-1 mice. Xenobiotica. 30(11). 1019–1032. 13 indexed citations

14.

Brown, Paul C., Patricia M. Sokolove, Denis McCann, James Stevens, & Thomas W. Jones. (1996). Induction of a Permeability Transition in Rat Kidney Mitochondria by Pentachlorobutadienyl Cysteine: A β-Lyase-Independent Process. Archives of Biochemistry and Biophysics. 331(2). 225–231. 4 indexed citations

15.

McCann, Denis, et al.. (1994). Sulfation of Di- and Tricyclic Phenols by Rat Liver Aryl Sulfotransferase Isozymes. Archives of Biochemistry and Biophysics. 310(2). 325–331. 3 indexed citations

16.

Mangold, James B., et al.. (1993). Aryl sulfotransferase-IV-catalyzed sulfation of aryl oximes: steric and substituent effects. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1163(2). 217–222. 4 indexed citations

17.

Hayden, Patrick, Yun Yang, Anthony J. I. Ward, et al.. (1991). Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine. Biochemistry. 30(24). 5935–5943. 23 indexed citations

18.

Mangold, Bonnie L.K., et al.. (1990). Self-catalyzed irreversible inactivation of rat hepatic aryl sulfotransferase IV by Nhydroxy-2-acetylaminofluorene. Carcinogenesis. 11(9). 1563–1567. 9 indexed citations

19.

Birge, Raymond B., John B. Bartolone, Denis McCann, et al.. (1989). Selective protein arylation by acetaminophen and 2,6-dimethylacetaminophen in cultured hepatocytes from phenobarbital-induced and uninduced mice. Biochemical Pharmacology. 38(24). 4429–4438. 26 indexed citations

20.

Mangold, James B., et al.. (1989). Sulfation of mono- and diaryl oximes by aryl sulfotransferase isozymes. Biochimica et Biophysica Acta (BBA) - General Subjects. 991(3). 453–458. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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