Timothy A. Vortherms

1.3k total citations
21 papers, 874 citations indexed

About

Timothy A. Vortherms is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Timothy A. Vortherms has authored 21 papers receiving a total of 874 indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 7 papers in Cellular and Molecular Neuroscience and 5 papers in Physiology. Recurrent topics in Timothy A. Vortherms's work include Receptor Mechanisms and Signaling (8 papers), Ion channel regulation and function (6 papers) and Neuropeptides and Animal Physiology (5 papers). Timothy A. Vortherms is often cited by papers focused on Receptor Mechanisms and Signaling (8 papers), Ion channel regulation and function (6 papers) and Neuropeptides and Animal Physiology (5 papers). Timothy A. Vortherms collaborates with scholars based in United States, United Kingdom and Belgium. Timothy A. Vortherms's co-authors include Bryan L. Roth, Jie Shen, Anne Tscherter, Matthew S. Goldberg, Giuseppina Martella, Tohru Kitada, Emmanuel N. Pothos, Antonio Pisani, Cinzia Costa and Giorgio Bernardi and has published in prestigious journals such as Journal of Biological Chemistry, Neuron and Biochemistry.

In The Last Decade

Timothy A. Vortherms

21 papers receiving 859 citations

Peers

Countries citing papers authored by Timothy A. Vortherms

Since Specialization

Citations

This map shows the geographic impact of Timothy A. Vortherms's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy A. Vortherms with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy A. Vortherms more than expected).

Fields of papers citing papers by Timothy A. Vortherms

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy A. Vortherms. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy A. Vortherms. The network helps show where Timothy A. Vortherms may publish in the future.

Co-authorship network of co-authors of Timothy A. Vortherms

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy A. Vortherms. A scholar is included among the top collaborators of Timothy A. Vortherms based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy A. Vortherms. Timothy A. Vortherms is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Suppression of superoxide/hydrogen peroxide production at mitochondrial site IQ decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet 2023 ·Free Radical Biology and Medicine ·Mark A. Watson, (unknown), (unknown), Hoi Shan Wong, Pratiksha Dighe, Bryan McKibben, Stephan Riedmaier, Amy Siu, James S. Polakowski, Jason A. Segreti, Xiaoqin Liu, (unknown), (unknown), Nathan J. Gesmundo, Zhi Wang, Timothy A. Vortherms, Martin D. Brand	7
2	Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222 2019 ·Journal of Pharmacology and Experimental Therapeutics ·Ashvani K. Singh, Yihong Fan, Corina Balut, (unknown), Arlene M. Manelli, Andrew M. Swensen, Ying Jia, Torben R. Neelands, Timothy A. Vortherms, Bo Liu, (unknown), Xueqing Wang, Wenqing Gao, Tzyh‐Chang Hwang, (unknown), Douglas Cyr, Philip R. Kym, Katja Conrath, Chris Tse	22
3	Discovery of 4-[(2 R ,4 R )-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2 H -chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis 2017 ·Journal of Medicinal Chemistry ·Xueqing Wang, Bo Liu, (unknown), Clinton M. Yeung, Andrew R. Bogdan, Stephen N. Greszler, Ashvani K. Singh, Yihong Fan, Andrew M. Swensen, Timothy A. Vortherms, Corina Balut, Ying Jia, Kelly E. Desino, Wenqing Gao, (unknown), Chris Tse, Philip R. Kym	60
4	Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain 2013 ·Bioorganic & Medicinal Chemistry Letters ·Xenia Beebe, Clinton M. Yeung, (unknown), Shashank Shekhar, Timothy A. Vortherms, Loan Miller, Ivan Milicic, Andrew M. Swensen, Chang Zhu, Patricia N. Banfor, Jill M. Wetter, Kennan C. Marsh, Michael F. Jarvis, Victoria Scott, Michael R. Schrimpf, (unknown)	7
5	An Automated Electrophysiological Assay for Differentiating Ca _V 2.2 Inhibitors Based on State Dependence and Kinetics 2012 ·Assay and Drug Development Technologies ·Andrew M. Swensen, Wende Niforatos, Timothy A. Vortherms, Richard J. Perner, Tao Li, Michael R. Schrimpf, Victoria Scott, Lance Lee, Michael F. Jarvis, Steve McGaraughty	4
6	Discovery of diphenyl lactam derivatives as N-type calcium channel blockers 2012 ·Bioorganic & Medicinal Chemistry Letters ·George Doherty, Pramila Bhatia, Timothy A. Vortherms, Kennan C. Marsh, Jill M. Wetter, Helmut Mack, Victoria Scott, Michael F. Jarvis, Andrew O. Stewart	7
7	A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats 2011 ·Biochemical Pharmacology ·Victoria Scott, Timothy A. Vortherms, Wende Niforatos, Andrew M. Swensen, Torben R. Neelands, Ivan Milicic, Patricia N. Banfor, (unknown), Chengmin Zhong, Gricelda Simler, Cenchen Zhan, Natalie A. Bratcher, Janel M. Boyce‐Rustay, Chang Zhu, Pramila Bhatia, George Doherty, Helmut Mack, Andrew O. Stewart, Michael F. Jarvis	27
8	Comparative analysis of inactivated-state block of N-type (Cav2.2) calcium channels 2011 ·Inflammation Research ·Timothy A. Vortherms, Andrew M. Swensen, Wende Niforatos, James T. Limberis, Torben R. Neelands, (unknown), Rama Thimmapaya, Diana L. Donnelly‐Roberts, Marian T. Namovic, Di Zhang, (unknown), Ruth L. Martin, Carol S. Surowy, Michael F. Jarvis, Victoria Scott	5
9	Cloning and characterization of the monkey histamine H3 receptor isoforms 2008 ·European Journal of Pharmacology ·Marina I. Strakhova, Gerard B. Fox, Tracy L. Carr, David G. Witte, Timothy A. Vortherms, Arlene M. Manelli, Thomas R. Miller, Betty Yao, Jorge D. Brioni, Timothy A. Esbenshade	10
10	cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), A New Histamine H₄R Antagonist that Blocks Pain Responses against Carrageenan-Induced Hyperalgesia 2008 ·Journal of Medicinal Chemistry ·Huaqing Liu, Robert J. Altenbach, Tracy L. Carr, Prasant Chandran, Gin C. Hsieh, (unknown), Arlene M. Manelli, Ivan Milicic, Kennan C. Marsh, Thomas R. Miller, Marina I. Strakhova, Timothy A. Vortherms, (unknown), Jill M. Wetter, David G. Witte, Prisca Honoré, Timothy A. Esbenshade, Jorge D. Brioni, Marlon Cowart	41
11	In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: Trends across multiple chemical series 2007 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Lawrence A. Black, Thomas R. Miller, Timothy A. Vortherms, Timothy A. Esbenshade, Arthur A. Hancock, Marlon Cowart	12
12	Differential Helical Orientations among Related G Protein-coupled Receptors Provide a Novel Mechanism for Selectivity 2006 ·Journal of Biological Chemistry ·Timothy A. Vortherms, Philip D. Mosier, Richard B. Westkaemper, Bryan L. Roth	28
13	Salvinorin A: From Natural Product to Human Therapeutics 2006 ·Molecular Interventions ·Timothy A. Vortherms, (unknown)	65
14	Nigrostriatal Dopaminergic Deficits and Hypokinesia Caused by Inactivation of the Familial Parkinsonism-Linked Gene DJ-1 2005 ·Neuron ·Matthew S. Goldberg, Antonio Pisani, Marián Haburčák, Timothy A. Vortherms, Tohru Kitada, Cinzia Costa, Youren Tong, Giuseppina Martella, Anne Tscherter, Andreá Maria Eleutério de Barros Lima Martins, Giorgio Bernardi, Bryan L. Roth, Emmanuel N. Pothos, Paolo Calabresi, Jie Shen	416
15	D2 dopamine receptor-induced sensitization of adenylyl cyclase type 1 is Gαs independent 2005 ·Neuropharmacology ·Timothy A. Vortherms, Chau H. Nguyen, Murat Bastepe, Harald Jüppner, Val J. Watts	16
16	Identification of the Molecular Mechanisms by Which the Diterpenoid Salvinorin A Binds to κ-Opioid Receptors 2005 ·Biochemistry ·Feng Yan, Philip D. Mosier, Richard B. Westkaemper, Jeremy Stewart, Jordan K. Zjawiony, Timothy A. Vortherms, Douglas J. Sheffler, Bryan L. Roth	72
17	Autoxidation of Salvinorin A under Basic Conditions 2005 ·The Journal of Organic Chemistry ·Thomas A. Munro, (unknown), Bryan L. Roth, Timothy A. Vortherms, Mark A. Rizzacasa	15
18	Sensitization of Neuronal A2A Adenosine Receptors after Persistent D2 Dopamine Receptor Activation 2004 ·Journal of Pharmacology and Experimental Therapeutics ·Timothy A. Vortherms, Val J. Watts	37
19	Using Molecular Tools to Dissect the Role of Gαs in Sensitization of AC1 2004 ·Molecular Pharmacology ·Timothy A. Vortherms, Chau H. Nguyen, Catherine H. Berlot, Val J. Watts	11
20	Adrenergic agonists induce heterologous sensitization of adenylate cyclase in NS20Y‐D_2L cells 2001 ·FEBS Letters ·Christopher A. Johnston, Medhane Cumbay, Timothy A. Vortherms, Val J. Watts	5

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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