Thomas A. Chappie

927 total citations
12 papers, 580 citations indexed

About

Thomas A. Chappie is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Thomas A. Chappie has authored 12 papers receiving a total of 580 indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 6 papers in Organic Chemistry and 4 papers in Pharmacology. Recurrent topics in Thomas A. Chappie's work include Phosphodiesterase function and regulation (7 papers), Receptor Mechanisms and Signaling (4 papers) and Cholinesterase and Neurodegenerative Diseases (4 papers). Thomas A. Chappie is often cited by papers focused on Phosphodiesterase function and regulation (7 papers), Receptor Mechanisms and Signaling (4 papers) and Cholinesterase and Neurodegenerative Diseases (4 papers). Thomas A. Chappie collaborates with scholars based in United States. Thomas A. Chappie's co-authors include Frank S. Menniti, Christopher J. Schmidt, John M. Humphrey, Xinjun Hou, Christopher J. Helal, Patrick R. Verhoest, Travis T. Wager, Elizabeth M. Beck, Jayvardhan Pandit and Laigao Chen and has published in prestigious journals such as Journal of Medicinal Chemistry, The Journal of Organic Chemistry and Tetrahedron Letters.

In The Last Decade

Thomas A. Chappie

12 papers receiving 560 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Thomas A. Chappie United States 11 396 219 160 102 44 12 580
Loan Miller United States 15 211 0.5× 121 0.6× 173 1.1× 145 1.4× 42 1.0× 23 709
Hartmut E. Greiner Germany 17 394 1.0× 100 0.5× 234 1.5× 314 3.1× 47 1.1× 32 839
Jonathan C. O’Connell United States 13 489 1.2× 113 0.5× 65 0.4× 194 1.9× 26 0.6× 18 585
Laura Iturrino Belgium 16 294 0.7× 89 0.4× 268 1.7× 161 1.6× 23 0.5× 23 577
Bernard Levet‐Trafit Switzerland 9 379 1.0× 87 0.4× 142 0.9× 273 2.7× 22 0.5× 9 727
David Thomae Belgium 13 223 0.6× 82 0.4× 248 1.6× 105 1.0× 59 1.3× 36 502
Michel Maillard United States 12 366 0.9× 70 0.3× 191 1.2× 103 1.0× 11 0.3× 16 698
José-Ignacio Andrés Belgium 8 176 0.4× 65 0.3× 67 0.4× 68 0.7× 29 0.7× 9 302
Kamil Kuder Poland 16 406 1.0× 117 0.5× 159 1.0× 122 1.2× 23 0.5× 47 640
Meryem Köse Germany 16 349 0.9× 42 0.2× 210 1.3× 136 1.3× 15 0.3× 25 641

Countries citing papers authored by Thomas A. Chappie

Since Specialization
Citations

This map shows the geographic impact of Thomas A. Chappie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas A. Chappie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas A. Chappie more than expected).

Fields of papers citing papers by Thomas A. Chappie

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas A. Chappie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas A. Chappie. The network helps show where Thomas A. Chappie may publish in the future.

Co-authorship network of co-authors of Thomas A. Chappie

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas A. Chappie. A scholar is included among the top collaborators of Thomas A. Chappie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas A. Chappie. Thomas A. Chappie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

12 of 12 papers shown
1.
Chappie, Thomas A., Claude Ambroise, Markus Boehm, et al.. (2022). Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators. ACS Medicinal Chemistry Letters. 13(1). 55–62. 10 indexed citations
2.
Menniti, Frank S., Thomas A. Chappie, & Christopher J. Schmidt. (2021). PDE10A Inhibitors—Clinical Failure or Window Into Antipsychotic Drug Action?. Frontiers in Neuroscience. 14. 600178–600178. 36 indexed citations
3.
Humphrey, John M., Matthew A. Movsesian, Christopher W. am Ende, et al.. (2018). Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1. Journal of Medicinal Chemistry. 61(10). 4635–4640. 24 indexed citations
4.
Wager, Travis T., Thomas A. Chappie, Ramalakshmi Y. Chandrasekaran, et al.. (2016). Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chemical Neuroscience. 8(1). 165–177. 21 indexed citations
5.
McAllister, Laura A., Kieran F. Geoghegan, Vinod D. Parikh, et al.. (2014). Chemoproteomics Demonstrates Target Engagement and Exquisite Selectivity of the Clinical Phosphodiesterase 10A Inhibitor MP-10 in Its Native Environment. ACS Chemical Biology. 9(12). 2823–2832. 22 indexed citations
6.
7.
Chappie, Thomas A., Christopher J. Helal, & Xinjun Hou. (2012). Current Landscape of Phosphodiesterase 10A (PDE10A) Inhibition. Journal of Medicinal Chemistry. 55(17). 7299–7331. 74 indexed citations
8.
Humphrey, John M., Eric P. Arnold, Thomas A. Chappie, et al.. (2009). Diastereoselective Synthesis of 2,3,6-Trisubstituted Piperidines. The Journal of Organic Chemistry. 74(12). 4525–4536. 15 indexed citations
9.
Menniti, Frank S., Thomas A. Chappie, John M. Humphrey, & Christopher J. Schmidt. (2007). Phosphodiesterase 10A inhibitors: a novel approach to the treatment of the symptoms of schizophrenia.. PubMed. 8(1). 54–9. 102 indexed citations
10.
Chappie, Thomas A., John M. Humphrey, Martin P. Allen, et al.. (2006). Discovery of a Series of 6,7-Dimethoxy-4-pyrrolidylquinazoline PDE10A Inhibitors. Journal of Medicinal Chemistry. 50(2). 182–185. 93 indexed citations
11.
Chappie, Thomas A., A. DUNAISKIS, Anton Fliri, et al.. (1998). Synthesis, sar and pharmacology of CP-293,019: A potent, selective dopamine D4 receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 8(7). 725–730. 28 indexed citations
12.
Chappie, Thomas A., et al.. (1996). Application of diazodecomposition reactions in tandem with [2,3]-sigmatropic rearrangements to prepare substituted azabicyclic ring systems. Tetrahedron Letters. 37(36). 6523–6526. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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