Thaddeus A. Tomaszek

3.4k citations

40 papers · 2.2k indexed · h-index 23

Co-authors: Thomas D. Meek Scott K. Thompson Thomas J. Carr Geoffrey B. Dreyer Maxine Gowen Mark A. Levy Mary J. Bossard Fred H. Drake
Topics: HIV/AIDS drug development and treatment (14 papers)HIV Research and Treatment (12 papers)Bone Metabolism and Diseases (11 papers)
Cited by: Virology Infectious Diseases Cancer Research
Journals: Nature Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United States United Kingdom

In The Last Decade

Thaddeus A. Tomaszek

40 papers receiving 2.1k citations

Peers

Countries citing papers authored by Thaddeus A. Tomaszek

Since Specialization

Citations

This map shows the geographic impact of Thaddeus A. Tomaszek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thaddeus A. Tomaszek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thaddeus A. Tomaszek more than expected).

Fields of papers citing papers by Thaddeus A. Tomaszek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thaddeus A. Tomaszek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thaddeus A. Tomaszek. The network helps show where Thaddeus A. Tomaszek may publish in the future.

Co-authorship network of co-authors of Thaddeus A. Tomaszek

This figure shows the co-authorship network connecting the top 25 collaborators of Thaddeus A. Tomaszek. A scholar is included among the top collaborators of Thaddeus A. Tomaszek based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thaddeus A. Tomaszek. Thaddeus A. Tomaszek is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Azepanone-based inhibitors of human cathepsin S: Optimization of selectivity via the P2 substituent 2011 ·Bioorganic & Medicinal Chemistry Letters ·Jeffrey K. Kerns,Hong Nie,William E. Bondinell,Katherine L. Widdowson,Dennis S. Yamashita,A. H. ABD EL RAHMAN,Patricia L. Podolin,Donald C. Carpenter,Qi Jin,(unknown),Xiaoyang Dong,Neysa Nevins,Paul M. Keller,(unknown),Thaddeus A. Tomaszek	10
2	A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys 2006 ·Bone ·Sanjay Kumar,Lauren Dare,Janice A. Vasko-Moser,Ian E. James,Simon Blake,David J. Rickard,Shing Mei Hwang,Thaddeus A. Tomaszek,Dennis S. Yamashita,Robert W. Marquis,Hye-Ja Oh,(unknown),Daniel F. Veber,Maxine Gowen,Michael W. Lark,George B. Stroup	104
3	2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV 2005 ·Bioorganic & Medicinal Chemistry Letters ·Curt D. Haffner,Darryl McDougald,(unknown),Brian Thompson,(unknown),Jing Fang,Jonathan Y. Bass,James M. Lenhard,Dallas K. Croom,(unknown),Thaddeus A. Tomaszek,Donavon J. McConn,Kevin J. Wells‐Knecht,Paul Johnson	20
4	Benzodioxocin‐3‐ones and N‐acyl‐3‐amino‐3‐buten‐2‐ones: novel classes of cathepsin K cysteine protease inhibitors^* 2004 ·Journal of Peptide Research ·Dennis S. Yamashita,(unknown),Hong Lin,Binghe Wang,Stone D.‐H. Shi,Chad Quinn,Mark E. Hemling,(unknown),Thaddeus A. Tomaszek,Daniel F. Veber	3
5	An Azepanone-Based Inhibitor of Human Cathepsin K with Improved Oral Bioavailability in the Rat and the Monkey 2003 ·Molecular Pharmaceutics ·Robert W. Marquis,Keith W. Ward,Theresa J. Roethke,Brian R. Smith,Yu Ru,Dennis S. Yamashita,Thaddeus A. Tomaszek,Peter D. Gorycki,(unknown),Ian E. James,George B. Stroup,Michael W. Lark,Maxine Gowen,Daniel F. Veber	6
6	Potent and Selective Cathepsin L Inhibitors Do Not Inhibit Human Osteoclast Resorption in Vitro 2001 ·Journal of Biological Chemistry ·Ian E. James,Robert W. Marquis,Simon Blake,Shing Mei Hwang,Catherine J. Gress,Yu Ru,Denise Zembryki,Dennis S. Yamashita,Michael S. McQueney,Thaddeus A. Tomaszek,Hye-Ja Oh,Maxine Gowen,Daniel F. Veber,Michael W. Lark	28
7	Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K 1999 ·Bioorganic & Medicinal Chemistry Letters ·Kevin J. Duffy,Lance H. Ridgers,Renée L. DesJarlais,Thaddeus A. Tomaszek,Mary J. Bossard,Scott K. Thompson,Richard M. Keenan,Daniel F. Veber	12
8	Structure-Based Design of Cathepsin K Inhibitors Containing a Benzyloxy-Substituted Benzoyl Peptidomimetic 1998 ·Journal of Medicinal Chemistry ·Scott K. Thompson,Ward W. Smith,Baoguang Zhao,(unknown),Thaddeus A. Tomaszek,David G. Tew,Mark A. Levy,Cheryl A. Janson,Karla D'Alessio,Michael S. McQueney,(unknown),Christopher S. Jones,Renée L. DesJarlais,Sherin S. Abdel‐Meguid,Daniel F. Veber	17
9	Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K 1998 ·Journal of the American Chemical Society ·Renée L. DesJarlais,Dennis S. Yamashita,Hye-Ja Oh,Irene N. Uzinskas,Karl F. Erhard,Andrew C. Allen,R. Curtis Haltiwanger,Baoguang Zhao,Ward W. Smith,Sherin S. Abdel‐Meguid,Karla D'Alessio,Cheryl A. Janson,Michael S. McQueney,Thaddeus A. Tomaszek,Mark A. Levy,Daniel F. Veber	32
10	Identification of a Loop Outside the Active Site Cavity of the Human Immunodeficiency Virus Proteases Which Confers Inhibitor Specificity 1997 ·Biochemistry ·Eric M. Towler,Scott K. Thompson,Thaddeus A. Tomaszek,Christine Debouck	9
11	Proteolytic Activity of Human Osteoclast Cathepsin K 1996 ·Journal of Biological Chemistry ·Mary J. Bossard,Thaddeus A. Tomaszek,Scott K. Thompson,Bernard Y. Amegadzie,Charles R. Hanning,Christopher S. Jones,(unknown),Dean E. McNulty,Fred H. Drake,Maxine Gowen,Mark A. Levy	404
12	A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of .gamma.-turn mimetics into a model substrate 1993 ·Journal of Medicinal Chemistry ·K. A. NEWLANDER,James F. Callahan,M. Lane Moore,Thaddeus A. Tomaszek,William F. Huffman	35
13	A symmetric inhibitor binds HIV-1 protease asymmetrically 1993 ·Biochemistry ·Geoffrey B. Dreyer,Jeffrey C. Boehm,Balan Chenera,Renée L. DesJarlais,Anne M. Hassell,Thomas D. Meek,Thaddeus A. Tomaszek,(unknown)	58
14	Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays 1992 ·Biochemistry ·Geoffrey B. Dreyer,Dennis M. Lambert,Thomas D. Meek,Thomas J. Carr,Thaddeus A. Tomaszek,Annabellee V. Fernandez,H F Bartus,(unknown),(unknown)	110
15	Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease 1992 ·Biochemistry ·Thaddeus A. Tomaszek,Michael L. Moore,James E. Strickler,(unknown),(unknown),Brian W. Metcalf,Anne M. Hassell,Geoffrey B. Dreyer,(unknown)	35
16	Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease 1991 ·Biochemistry ·(unknown),Ingrid C. Deckman,Michael D. Minnich,Jeffrey S. Culp,Samuel P. Franklin,Geoffrey B. Dreyer,Thaddeus A. Tomaszek,Christine Debouck,Thomas D. Meek	42
17	Human immunodeficiency virus-1 protease. 1. Initial velocity studies and kinetic characterization of reaction intermediates by oxygen-18 isotope exchange 1991 ·Biochemistry ·(unknown),Thaddeus A. Tomaszek,Gerald D. Roberts,Steven A. Carr,Victoria W. Magaard,(unknown),Stephen A. Fakhoury,M. Lane Moore,Michael D. Minnich	93
18	Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism 1991 ·Biochemistry ·(unknown),Thaddeus A. Tomaszek,Thomas D. Meek	199
19	Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues 1990 ·Nature ·Thomas D. Meek,Dennis M. Lambert,Geoffrey B. Dreyer,Thomas J. Carr,Thaddeus A. Tomaszek,Michael L. Moore,James E. Strickler,Christine Debouck,(unknown),Thomas J. Matthews,Brian W. Metcalf,Stephen R. Petteway	201
20	A novel, convenient assay of lanosterol 14α-demethylase 1989 ·Bioorganic Chemistry ·Mary J. Bossard,Thaddeus A. Tomaszek,Brian W. Metcalf,Jerry L. Adams	8

About Thaddeus A. Tomaszek

Thaddeus A. Tomaszek is a scholar working on Virology, Infectious Diseases and Immunology and Allergy, having authored 40 papers that have together received 2.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (14 papers), HIV Research and Treatment (12 papers) and Bone Metabolism and Diseases (11 papers). The work is most often cited by research in Virology (594 citations), Infectious Diseases (687 citations) and Cancer Research (346 citations). Thaddeus A. Tomaszek has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include Thomas D. Meek, Scott K. Thompson, Thomas J. Carr, Geoffrey B. Dreyer, Maxine Gowen, Mark A. Levy, Mary J. Bossard, Fred H. Drake, Michael L. Moore and Daniel F. Veber. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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