Jeffrey K. Kerns

1.6k citations

20 papers · 978 indexed · h-index 15

Co-authors: James F. Callahan A. James Wilson Brian I. Carr Christopher J. Moody Yuji Nishikawa Craig S. Wilcox Qiyan Lin Kiyoshi Nakayama
Topics: Cytokine Signaling Pathways and Interactions (5 papers)Genomics, phytochemicals, and oxidative stress (4 papers)NF-κB Signaling Pathways (4 papers)
Cited by: Toxicology Organic Chemistry Molecular Biology
Journals: Journal of Biological Chemistry Angewandte Chemie International Edition PLoS ONE
Partner nations: United States United Kingdom China

In The Last Decade

Jeffrey K. Kerns

20 papers receiving 963 citations

Peers

Countries citing papers authored by Jeffrey K. Kerns

Since Specialization

Citations

This map shows the geographic impact of Jeffrey K. Kerns's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffrey K. Kerns with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffrey K. Kerns more than expected).

Fields of papers citing papers by Jeffrey K. Kerns

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffrey K. Kerns. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffrey K. Kerns. The network helps show where Jeffrey K. Kerns may publish in the future.

Co-authorship network of co-authors of Jeffrey K. Kerns

This figure shows the co-authorship network connecting the top 25 collaborators of Jeffrey K. Kerns. A scholar is included among the top collaborators of Jeffrey K. Kerns based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeffrey K. Kerns. Jeffrey K. Kerns is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein−Protein Interaction 2021 ·Journal of Medicinal Chemistry ·David L. Norton,William G. Bonnette,James F. Callahan,Maria G. Carr,Charlotte Griffiths-Jones,Tom D. Heightman,Jeffrey K. Kerns,Hong Nie,Sharna J. Rich,Caroline J. Richardson,William L. Rumsey,Yolanda Sánchez,Marcel L. Verdonk,Henriëtte M. G. Willems,William E. Wixted,(unknown),Alison J.‐A. Woolford,Zining Wu,Thomas G. Davies	23
2	Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress 2017 ·Journal of Pharmacology and Experimental Therapeutics ·John Yonchuk,Joseph P. Foley,Brian Bolognese,(unknown),William E. Wixted,(unknown),(unknown),(unknown),Yolanda Sánchez,Hong Nie,James F. Callahan,Jeffrey K. Kerns,Patricia L. Podolin	18
3	Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO 2014 ·PLoS ONE ·Anne Cleasby,Jeff Yon,Philip J. Day,Caroline J. Richardson,Ian J. Tickle,Pamela A. Williams,James F. Callahan,Robin A. E. Carr,N.O. Concha,Jeffrey K. Kerns,Hongwei Qi,Thomas D. Sweitzer,Paris Ward,Thomas G. Davies	202
4	Keap Calm, and Carry on Covalently 2013 ·Journal of Medicinal Chemistry ·A. James Wilson,Jeffrey K. Kerns,James F. Callahan,Christopher J. Moody	146
5	3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β 2011 ·Bioorganic & Medicinal Chemistry Letters ·David D. Miller,Paul Bamborough,J.A. Christopher,(unknown),(unknown),Geoffrey J. Cutler,Jeffrey K. Kerns,(unknown),Geoffrey W. Mellor,J. V. Morey,Mary A. Morse,Hong Nie,William L. Rumsey,(unknown)	13
6	Azepanone-based inhibitors of human cathepsin S: Optimization of selectivity via the P2 substituent 2011 ·Bioorganic & Medicinal Chemistry Letters ·Jeffrey K. Kerns,Hong Nie,William E. Bondinell,Katherine L. Widdowson,Dennis S. Yamashita,A. H. ABD EL RAHMAN,Patricia L. Podolin,Donald C. Carpenter,Qi Jin,(unknown),Xiaoyang Dong,Neysa Nevins,Paul M. Keller,(unknown),Thaddeus A. Tomaszek	10
7	Progress Towards the Development of Anti-Inflammatory Inhibitors of IKKβ 2009 ·Current Topics in Medicinal Chemistry ·Paul Bamborough,James F. Callahan,J.A. Christopher,Jeffrey K. Kerns,John Liddle,David D. Miller,Mary A. Morse,William L. Rumsey,(unknown)	21
8	Spongipyran synthetic studies. Total synthesis of (+)-spongistatin 2 2009 ·Tetrahedron ·Amos B. Smith,Qiyan Lin,Victoria A. Doughty,Linghang Zhuang,Mark D. McBriar,Jeffrey K. Kerns,Armen M. Boldi,Noriaki Murase,William H. Moser,Christopher S. Brook,Clay S. Bennett,Kiyoshi Nakayama,(unknown),Robert E. Lee Trout	22
9	Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β) 2009 ·Journal of Medicinal Chemistry ·J.A. Christopher,Paul Bamborough,Catherine M. Alder,Amanda Campbell,Geoffrey J. Cutler,Kenneth Down,(unknown),(unknown),Jeffrey K. Kerns,Fiona S. Lucas,Geoffrey W. Mellor,David D. Miller,Mary A. Morse,(unknown),William L. Rumsey,Yemisi Solanke,(unknown)	29
10	Efficient and Scalable Synthesisof 3,5,7-Trisubstituted 1H-Indazolesas Potent IKK2 Inhibitors 2008 ·Synlett ·(unknown),Jakob Busch‐Petersen,Jianghe Deng,Christine Edwards,Zhaoguo Zhang,Jeffrey K. Kerns	6
11	3-Arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides as novel and selective CXCR2 antagonists 2007 ·Bioorganic & Medicinal Chemistry Letters ·Yonghui Wang,Jakob Busch‐Petersen,Feng Wang,Lanping Ma,(unknown),Jeffrey K. Kerns,Jian Jin,Michael R. Palovich,Jingkang Shen,Miriam Burman,James J. Foley,Dulcie B. Schmidt,(unknown),Henry M. Sarau,Katherine L. Widdowson	25
12	The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases 2007 ·Bioorganic & Medicinal Chemistry Letters ·J.A. Christopher,(unknown),Paul Bamborough,(unknown),Geoffrey J. Cutler,(unknown),(unknown),Jeffrey K. Kerns,Jeremy Kitson,Geoffrey W. Mellor,J. V. Morey,Mary A. Morse,(unknown),Champa Patel,(unknown),William L. Rumsey,Clive A. Smith,Michael J. Wilson	53
13	A Highly Convergent Synthesis of 2‐Phenyl Quinoline as Dual Antagonists for NK2 and NK3 Receptors 2005 ·Synthetic Communications ·Hongxing Yan,Jeffrey K. Kerns,Qi Jin,(unknown),Mary S. Barnette,James F. Callahan,Douglas W.P. Hay,Larry J. Jolivette,Mark A. Luttmann,Henry M. Sarau,Keith W. Ward,Katherine L. Widdowson,Zehong Wan	11
14	The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2 2001 ·Angewandte Chemie International Edition ·Amos B. Smith,Qiyan Lin,Victoria A. Doughty,Linghang Zhuang,Mark D. McBriar,Jeffrey K. Kerns,Christopher S. Brook,Noriaki Murase,Kiyoshi Nakayama	86
15	The Spongistatins: Architecturally Complex Natural Products—Part Two: Synthesis of the C(29–51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2 2001 ·Angewandte Chemie ·Amos B. Smith,Qiyan Lin,Victoria A. Doughty,Linghang Zhuang,Mark D. McBriar,Jeffrey K. Kerns,Christopher S. Brook,Noriaki Murase,Kiyoshi Nakayama	17
16	The Spongistatins: Architecturally Complex Natural Products—Part Two: Synthesis of the C(29–51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2 2001 ·Angewandte Chemie International Edition ·Amos B. Smith,Qiyan Lin,Victoria A. Doughty,Linghang Zhuang,Mark D. McBriar,Jeffrey K. Kerns,Christopher S. Brook,Noriaki Murase,Kiyoshi Nakayama	1
17	The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2 Financial support was provided by the National Institutes of Health (National Cancer Institute) through Grant CA-70329, a NIH Postdoctoral Fellowship to C.S.B., a Japan Society for Promotion of Science Fellowship to N.M., and a Royal Society Fulbright Fellowship to V.A.D. We also thank the Daiichi Pharmaceutical Co., Ltd, and the Tanabe Seiyaku Co., Ltd for financial support. Finally we thank Dr George T. Furst, Dr. Patrick J. Carroll, and Dr. Rakesh Kohli of the University of Pennsylvania Spectroscopic Service Center for assistance in securing and interpreting high-field NMR spectra, X-ray crystal structures, and mass spectra, respectively. 2001 ·PubMed ·Amos B. Smith,Qiyan Lin,Victoria A. Doughty,Linghang Zhuang,Mark D. McBriar,Jeffrey K. Kerns,Christopher S. Brook,Noriaki Murase,Kiyoshi Nakayama	23
18	Cdc25 inhibition and cell cycle arrest by a synthetic thioalkyl vitamin K analogue. 2000 ·PubMed ·Kenji Tamura,Eileen C. Southwick,Jeffrey K. Kerns,(unknown),Brian I. Carr,Craig S. Wilcox,John S. Lazo	93
19	Inhibition of Hepatoma Cell Growth in Vitro by Arylating and Non-arylating K Vitamin Analogs 1999 ·Journal of Biological Chemistry ·Yuji Nishikawa,Ziqiu Wang,Jeffrey K. Kerns,Craig S. Wilcox,Brian I. Carr	45
20	Growth Inhibition of Hepatoma Cells Induced by Vitamin K and Its Analogs 1995 ·Journal of Biological Chemistry ·Yuji Nishikawa,Brian I. Carr,Meifang Wang,Siddhartha Kar,Frances M. Finn,Paul Dowd,(unknown),Jeffrey K. Kerns,Sriram Naganathan	134

About Jeffrey K. Kerns

Jeffrey K. Kerns is a scholar working on Toxicology, Pharmacology and Biotechnology, having authored 20 papers that have together received 978 indexed citations. Recurring topics across this work include Cytokine Signaling Pathways and Interactions (5 papers), Genomics, phytochemicals, and oxidative stress (4 papers) and NF-κB Signaling Pathways (4 papers). The work is most often cited by research in Toxicology (81 citations), Organic Chemistry (358 citations) and Molecular Biology (646 citations). Jeffrey K. Kerns has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include James F. Callahan, A. James Wilson, Brian I. Carr, Christopher J. Moody, Yuji Nishikawa, Craig S. Wilcox, Qiyan Lin, Kiyoshi Nakayama, Linghang Zhuang and Amos B. Smith. Their work appears in journals such as Journal of Biological Chemistry, Angewandte Chemie International Edition and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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