Stuart H. Orkin

12.9k total citations · 3 hit papers
62 papers, 8.4k citations indexed

About

Stuart H. Orkin is a scholar working on Molecular Biology, Immunology and Hematology. According to data from OpenAlex, Stuart H. Orkin has authored 62 papers receiving a total of 8.4k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Molecular Biology, 14 papers in Immunology and 13 papers in Hematology. Recurrent topics in Stuart H. Orkin's work include Epigenetics and DNA Methylation (12 papers), Acute Myeloid Leukemia Research (8 papers) and Cancer-related gene regulation (6 papers). Stuart H. Orkin is often cited by papers focused on Epigenetics and DNA Methylation (12 papers), Acute Myeloid Leukemia Research (8 papers) and Cancer-related gene regulation (6 papers). Stuart H. Orkin collaborates with scholars based in United States, Austria and Switzerland. Stuart H. Orkin's co-authors include Charles W.M. Roberts, Yuko Fujiwara, Konrad Hochedlinger, Jonghwan Kim, Mary C. Dinauer, Carl R. Walkley, David I. K. Martin, George L. Mutter, Leonard I. Zon and David A. Williams and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Stuart H. Orkin

61 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

2007 862 citations Carl R. Walkley, Stuart H. Orkin et al. Nature profile →
Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

1995 792 citations Jonathan Pollock, David A. Williams et al. Nature Genetics profile →
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain

1986 426 citations Stuart H. Orkin et al. Nature profile →

Peers

Countries citing papers authored by Stuart H. Orkin

Since Specialization

Citations

This map shows the geographic impact of Stuart H. Orkin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stuart H. Orkin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stuart H. Orkin more than expected).

Fields of papers citing papers by Stuart H. Orkin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stuart H. Orkin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stuart H. Orkin. The network helps show where Stuart H. Orkin may publish in the future.

Co-authorship network of co-authors of Stuart H. Orkin

This figure shows the co-authorship network connecting the top 25 collaborators of Stuart H. Orkin. A scholar is included among the top collaborators of Stuart H. Orkin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stuart H. Orkin. Stuart H. Orkin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer 2021 ·Genes & Development ·Harshabad Singh, Davide Seruggia, Shariq Madha, Madhurima Saxena, Ankur K. Nagaraja, Zhong Wu, Jin Zhou, Aaron J. Huebner, (unknown), (unknown), Konrad Hochedlinger, Stuart H. Orkin, Adam J. Bass, Jason L. Hornick, Ramesh A. Shivdasani	14
2	An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells 2020 ·Cell ·Sarah Bowling, Duluxan Sritharan, Fernando G. Osorio, Maximilian Nguyen, Priscilla Cheung, Alejo Rodriguez-Fraticelli, Sachin Patel, Wei-Chien Yuan, Yuko Fujiwara, Bin E. Li, Stuart H. Orkin, Sahand Hormoz, Fernando D. Camargo	194
3	Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment 2018 ·Scientific Reports ·(unknown), Ke-Yue Ma, (unknown), Jianjun Shen, Jessica N. Lancaster, S. Stephen Yi, Huafeng Xie, Stuart H. Orkin, Nancy R. Manley, Lauren I. R. Ehrlich, Ning Jiang, Ellen R. Richie	5
4	Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells 2018 ·Scientific Reports ·Glenn MacLean, (unknown), Jialiang Huang, (unknown), Matthew C. Canver, Stuart H. Orkin	15
5	Transcription control by the ENL YEATS domain in acute leukaemia 2017 ·RePEc: Research Papers in Economics ·Michael A. Erb, Thomas G. Scott, Bin E. Li, Huafeng Xie, Joshiawa Paulk, Hyuk‐Soo Seo, Amanda Souza, Justin M. Roberts, Shiva Dastjerdi, Dennis L. Buckley, Neville E. Sanjana, Ophir Shalem, Behnam Nabet, Rhamy Zeid, (unknown), Sirano Dhe‐Paganon, Feng Zhang, Stuart H. Orkin, Georg Winter, James E. Bradner	1
6	Transcription control by the ENL YEATS domain in acute leukaemia 2017 ·Nature ·Michael A. Erb, Thomas G. Scott, Bin E. Li, Huafeng Xie, Joshiawa Paulk, Hyuk‐Soo Seo, Amanda Souza, Justin M. Roberts, Shiva Dastjerdi, Dennis L. Buckley, Neville E. Sanjana, Ophir Shalem, Behnam Nabet, Rhamy Zeid, (unknown), Sirano Dhe‐Paganon, Feng Zhang, Stuart H. Orkin, Georg Winter, James E. Bradner	204
7	Loss of Ezh2 synergizes with JAK2 -V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis 2016 ·The Journal of Experimental Medicine ·Takafumi Shimizu, Lucia Kubovčáková, Ronny Nienhold, Jakub Zmajkovic, Sara C. Meyer, Hui Hao-Shen, Florian Geier, Stephan Dirnhofer, Paola Guglielmelli, Alessandro M. Vannucchi, Jelena D. Milosevic Feenstra, Róbert Královics, Stuart H. Orkin, Radek C. Skoda	82
8	Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer 2016 ·Cancer Cell ·Michela Serresi, Gaetano Gargiulo, Natalie Proost, Bjørn Siteur, Matteo Cesaroni, Martijn Koppens, Huafeng Xie, (unknown), Danielle Hulsman, Elisabetta Citterio, Stuart H. Orkin, Anton Berns, Maarten van Lohuizen	5
9	Mapping Cellular Hierarchy by Single-Cell Analysis of the Cell Surface Repertoire 2013 ·Cell stem cell ·Guoji Guo, Sidinh Luc, Eugenio Marco, (unknown), Cong Peng, Marc A. Kerenyi, Semir Beyaz, Woojin Kim, Jian Xu, Partha Pratim Das, Tobias Neff, Keyong Zou, Guo‐Cheng Yuan, Stuart H. Orkin	175
10	Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas 2011 ·Oncogene ·Upal Basu-Roy, (unknown), Lalitha Ramanathapuram, Timothy Rapp, Judith A. Perry, Stuart H. Orkin, Alka Mansukhani, Claudio Basilico	198
11	DNA Methyltransferase 1 Is Essential for and Uniquely Regulates Hematopoietic Stem and Progenitor Cells 2009 ·Cell stem cell ·Jennifer J. Trowbridge, Jonathan W. Snow, Jonghwan Kim, Stuart H. Orkin	277
12	SnapShot: Hematopoiesis 2008 ·Cell ·Stuart H. Orkin, Leonard I. Zon	39
13	Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment 2007 ·Cell ·Carl R. Walkley, Jeremy M. Shea, Natalie A. Sims, Louise E. Purton, Stuart H. Orkin	329
14	ETV6-NTRK3 Fusion Oncogene Initiates Breast Cancer from Committed Mammary Progenitors via Activation of AP1 Complex 2007 ·Cancer Cell ·Zhe Li, Cristina E. Tognon, Frank J. Godinho, Laura Yasaitis, Hanno Hock, Jason I. Herschkowitz, (unknown), Eun-Ah Cho, Seong‐Jin Kim, Roderick T. Bronson, Charles M. Perou, Poul H. Sorensen, Stuart H. Orkin	108
15	Epigenetic Regulation of Hematopoietic Differentiation by Gfi-1 and Gfi-1b Is Mediated by the Cofactors CoREST and LSD1 2007 ·Molecular Cell ·Shireen Saleque, Jonghwan Kim, Heather M. Rooke, Stuart H. Orkin	315
16	Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production breakdown → 1995 ·Nature Genetics ·Jonathan Pollock, David A. Williams, (unknown), (unknown), Xunxiang Du, Jason S. Fisherman, Stuart H. Orkin, Claire M. Doerschuk, Mary C. Dinauer	792
17	Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice. 1995 ·The Journal of Experimental Medicine ·Radek C. Skoda, S F Tsai, Stuart H. Orkin, Philip Leder	27
18	Restriction of Neuroblastoma to the Prostate Gland In Transgenic Mice 1991 ·Molecular and Cellular Biology ·David G. Skalnik, David M. Dorfman, David A. Williams, Stuart H. Orkin	6
19	Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages 1990 ·Nature ·David I. K. Martin, (unknown), George L. Mutter, Stuart H. Orkin	415
20	Partial Correction of the Phagocyte Defect in Patients with X-Linked Chronic Granulomatous Disease by Subcutaneous Interferon Gamma 1988 ·New England Journal of Medicine ·R. Alan B. Ezekowitz, Mary C. Dinauer, Howard S. Jaffe, Stuart H. Orkin, Peter E. Newburger	200

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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