Steven Wink

849 citations

20 papers · 518 · h-index 11

Impact in

Pharmacology top 5%
- Drug-Induced Hepatotoxicity and Protection
- Pharmacogenetics and Drug Metabolism
Computational Theory and Mathematics top 5%
- Computational Drug Discovery Methods

Papers in

Molecular Biology 15
- Genomics, phytochemicals, and oxidative stress 6
- Viral Infectious Diseases and Gene Expression in Insects 3
Computational Theory and Mathematics 7
- Computational Drug Discovery Methods 7

Co-authors: Bob van de Water (18 shared papers)Steven Hiemstra (8 shared papers)Bram Herpers (4 shared papers)Hans de Bont (5 shared papers)Harry Vrieling (2 shared papers)Marije Niemeijer (5 shared papers)Erik H.J. Danen (2 shared papers)Lisa Fredriksson (2 shared papers)
Journals: Archives of Toxicology (4 papers)Chemical Research in Toxicology (2 papers)Toxicology in Vitro (2 papers)Biochemical Pharmacology (2 papers)Liver International (1 paper)
Partner nations: Netherlands United Kingdom United States

In The Last Decade

Steven Wink

20 papers receiving 517 citations

Peers

Countries citing papers authored by Steven Wink

Since Specialization

Citations

This map shows the geographic impact of Steven Wink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven Wink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven Wink more than expected).

Fields of papers citing papers by Steven Wink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven Wink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven Wink. The network helps show where Steven Wink may publish in the future.

Co-authors

The 25 scholars most cited alongside Steven Wink, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Steven Wink Line = papers co-authored together Steven Wink links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Drug-Induced Endoplasmic Reticulum and Oxidative Stress Responses Independently Sensitize Toward TNFα-Mediated Hepatotoxicity Toxicological Sciences ·Lisa Fredriksson, Steven Wink, Bram Herpers, Giulia Benedetti, Mackenzie Hadi, Hans de Bont, Geny M. M. Groothuis, Mirjam Luijten, Erik H.J. Danen, Marjo de Graauw, John H.N. Meerman, Bob van de Water	2014	71
2	Quantitative High Content Imaging of Cellular Adaptive Stress Response Pathways in Toxicity for Chemical Safety Assessment Chemical Research in Toxicology ·Steven Wink, Steven Hiemstra, Suzanna Huppelschoten, Erik H.J. Danen, Marije Niemeijer, Giel Hendriks, Harry Vrieling, Bram Herpers, Bob van de Water	2014	66
3	Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes Nature Communications ·Esmee Koedoot, Michiel Fokkelman, Vasiliki-Maria Rogkoti, Marcel Smid, Iris van de Sandt, Hans de Bont, Chantal Pont, Janna E. Klip, Steven Wink, Mieke Timmermans, Erik A.C. Wiemer, Peter Stoilov, John A. Foekens, Sylvia E. Le Dévédec, John W.M. Martens, Bob van de Water	2019	60
4	High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities Archives of Toxicology ·Steven Wink, Steven Hiemstra, Bram Herpers, Bob van de Water	2016	50
5	Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity Archives of Toxicology ·Bram Herpers, Steven Wink, Lisa Fredriksson, Zi Di, Giel Hendriks, Harry Vrieling, Hans de Bont, Bob van de Water	2015	48
6	Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury Archives of Toxicology ·Steven Wink, Steven Hiemstra, S. Huppelschoten, Janna E. Klip, Bob van de Water	2018	45
7	High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability Archives of Toxicology ·Steven Hiemstra, Sreenivasa Ramaiahgari, Steven Wink, Giulia Callegaro, Maarten Coonen, John H.N. Meerman, Danyel Jennen, Karen van den Nieuwendijk, Anita C. A. Dankers, Jan Snoeys, Hans de Bont, Leo Price, Bob van de Water	2019	40
8	Mining a human transcriptome database for chemical modulators of NRF2 PLoS ONE ·John P. Rooney, Brian N. Chorley, Steven Hiemstra, Steven Wink, Xuting Wang, Douglas A. Bell, Bob van de Water, J. Christopher Corton	2020	30
9	Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage Chemical Research in Toxicology ·Steven Hiemstra, Marije Niemeijer, Esmee Koedoot, Steven Wink, Janna E. Klip, Matthijs Vlasveld, Elisabeth de Zeeuw, Bram W. van Os, Andrew White, Bob van de Water	2016	27
10	Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases Frontiers in Genetics ·Elias Zgheib, Alice Limonciel, Xiaoqi Jiang, Anja Wilmes, Steven Wink, Bob van de Water, Annette Kopp‐Schneider, Frédéric Y. Bois, Paul Jennings	2018	22
11	Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury Biochemical Pharmacology ·Lukas S. Wijaya, Panuwat Trairatphisan, Attila Gábor, Marije Niemeijer, Jason Keet, Ariadna Alcalà Morera, Kirsten E Snijders, Steven Wink, Huan Yang, Stefan Schildknecht, James Stevens, Peter Bouwman, Hennicke Kamp, Jan G. Hengstler, Joost B. Beltman, Marcel Leist, Sylvia E. Le Dévédec, Julio Sáez-Rodríguez, Bob van de Water	2021	19
12	Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes Toxicology in Vitro ·Bas ter Braak, Marije Niemeijer, Ruben Boon, C. Parmentier, Audrey Baze, Lysiane Richert, Suzanna Huppelschoten, Steven Wink, Catherine M. Verfaillie, Bob van de Water	2021	10
13	FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells Biochemical Pharmacology ·Jichao He, Steven Wink, Hans de Bont, Sylvia E. Le Dévédec, Ying-Hui Zhang, Bob van de Water	2019	8
14	Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells Breast Cancer Research ·Bas ter Braak, Steven Wink, Esmee Koedoot, Chantal Pont, Christine L. E. Siezen, Jan Willem van der Laan, Bob van de Water	2015	6
15	System Microscopy of Stress Response Pathways in Cholestasis Research Methods in molecular biology ·Johannes P. Schimming, Bas ter Braak, Marije Niemeijer, Steven Wink, Bob van de Water	2019	4
16	The integrated stress response‐related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability Liver International ·Matthijs Vlasveld, Giulia Callegaro, Ciarán Fisher, Julie Eakins, Paul Walker, Samantha Lok, Siddh van Oost, Brechtje de Jong, Damiano Pellegrino‐Coppola, Gerhard A. Burger, Steven Wink, Bob van de Water	2024	4
17	Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses Toxicology in Vitro ·Bas ter Braak, Janna E. Klip, Steven Wink, Steven Hiemstra, Sarah Cooper, A. Middleton, Andrew White, Bob van de Water	2022	3
18	Collaborative SAR Modeling and Prospective In Vitro Validation of Oxidative Stress Activation in Human HepG2 Cells Journal of Chemical Information and Modeling ·Olivier J. M. Béquignon, José Carlos Gómez-Tamayo, Eelke B. Lenselink, Steven Wink, Steven Hiemstra, Chi Chung Lam, Domenico Gadaleta, Alessandra Roncaglioni, Ulf Norinder, Bob van de Water, Manuel Pastor, Gerard J. P. van Westen	2023	3
19	Systems microscopy to unravel cellular stress response signalling in drug induced liver injury Leiden Repository (Leiden University) ·Steven Wink	2015	1
20	Functional analysis of high-content high-throughput imaging data Journal of Applied Statistics ·Xiaoqi Jiang, Steven Wink, Bob van de Water, Annette Kopp‐Schneider	2016	1

About Steven Wink

Steven Wink is a scholar working on Molecular Biology, Computational Theory and Mathematics, Pharmacology, Cell Biology and Cancer Research, having authored 20 papers that have together received 518 indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (7 papers), Drug-Induced Hepatotoxicity and Protection (7 papers), Genomics, phytochemicals, and oxidative stress (6 papers), Endoplasmic Reticulum Stress and Disease (3 papers), Pharmacogenetics and Drug Metabolism (3 papers), Viral Infectious Diseases and Gene Expression in Insects (3 papers), MicroRNA in disease regulation (2 papers) and Cell Image Analysis Techniques (2 papers). The work is most often cited by research in Pharmacology (136 citations), Computational Theory and Mathematics (96 citations), Hepatology (48 citations), Small Animals (37 citations) and Cancer Research (71 citations). Steven Wink has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Bob van de Water, Steven Hiemstra, Bram Herpers, Hans de Bont, Harry Vrieling, Marije Niemeijer, Erik H.J. Danen, Lisa Fredriksson, John H.N. Meerman and Esmee Koedoot. Their work appears in journals such as Archives of Toxicology, Chemical Research in Toxicology, Toxicology in Vitro, Biochemical Pharmacology and Liver International.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Steven Wink

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Steven Wink

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