Bram Herpers

2.2k citations

34 papers · 1.6k indexed · h-index 22

Impact in

Pharmacology top 2%
- Drug-Induced Hepatotoxicity and Protection
- Pharmacogenetics and Drug Metabolism
Hepatology top 5%
- Liver physiology and pathology

Papers in ⓘ

Pharmacology 6
- Drug-Induced Hepatotoxicity and Protection 6
Oncology 11
- Cancer Cells and Metastasis 8
- Colorectal Cancer Treatments and Studies 3

Co-authors: Bob van de Water (14 shared papers)Cathérine Rabouille (6 shared papers)Jan N. M. Commandeur (3 shared papers)Leo Price (9 shared papers)Michiel W. den Braver (1 shared paper)Sreenivasa Ramaiahgari (1 shared paper)Valeska Terpstra (1 shared paper)Lisa Fredriksson (6 shared papers)
Journals: Archives of Toxicology (6 papers)Cancer Research (3 papers)International Journal of Molecular Sciences (2 papers)Annals of Oncology (2 papers)Developmental Cell (2 papers)
Partner nations: Netherlands United Kingdom United States

In The Last Decade

Bram Herpers

32 papers receiving 1.6k citations

Peers

Countries citing papers authored by Bram Herpers

Since Specialization

Citations

This map shows the geographic impact of Bram Herpers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bram Herpers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bram Herpers more than expected).

Fields of papers citing papers by Bram Herpers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bram Herpers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bram Herpers. The network helps show where Bram Herpers may publish in the future.

Co-authors

The 25 scholars most cited alongside Bram Herpers, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bram Herpers Line = papers co-authored together Bram Herpers links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 34 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies Archives of Toxicology ·Sreenivasa Ramaiahgari, Michiel W. den Braver, Bram Herpers, Valeska Terpstra, Jan N. M. Commandeur, Bob van de Water, Leo Price	2014	300
2	Drosophila Squid/hnRNP Helps Dynein Switch from a gurken mRNA Transport Motor to an Ultrastructural Static Anchor in Sponge Bodies Developmental Cell ·Rénald Delanoue, Bram Herpers, Jan Soetaert, Ilan Davis, Cathérine Rabouille	2007	94
3	Drosophila patterning is established by differential association of mRNAs with P bodies Nature Cell Biology ·Timothy T Weil, Richard M. Parton, Bram Herpers, Jan Soetaert, Tineke Veenendaal, Despina Xanthakis, Ian M. Dobbie, James M. Halstead, Rippei Hayashi, Cathérine Rabouille, Ilan Davis	2012	93
4	Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance Annals of Oncology ·Jolieke G. van Oosterwijk, Bram Herpers, D. W. Meijer, Inge H. Briaire‐de Bruijn, Anne‐Marie Cleton-Jansen, Hans Gelderblom, Bob van de Water, Judith V.M.G. Bovée	2011	92
5	mRNA Localization and ER-based Protein Sorting Mechanisms Dictate the Use of Transitional Endoplasmic Reticulum-Golgi Units Involved in Gurken Transport in Drosophila Oocytes Molecular Biology of the Cell ·Bram Herpers, Cathérine Rabouille	2004	77
6	Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·Juan Daniel Hernández Vargas, Bram Herpers, Andrew T. McKie, Sarah Gledhill, James M. McDonnell, Mieke van den Heuvel, K E Davies, Chris P. Ponting	2003	73
7	TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells Biochemical Pharmacology ·Giulia Benedetti, Lisa Fredriksson, Bram Herpers, John H.N. Meerman, Bob van de Water, Marjo de Graauw	2012	73
8	Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis Hepatology ·Lisa Fredriksson, Bram Herpers, Giulia Benedetti, Quraisha Matadin, Jordi Carreras‐Puigvert, Hans de Bont, Sanja Dragović, Nico Vermeulen, Jan N. M. Commandeur, Erik H.J. Danen, Marjo de Graauw, Bob van de Water	2011	73
9	Drug-Induced Endoplasmic Reticulum and Oxidative Stress Responses Independently Sensitize Toward TNFα-Mediated Hepatotoxicity Toxicological Sciences ·Lisa Fredriksson, Steven Wink, Bram Herpers, Giulia Benedetti, Mackenzie Hadi, Hans de Bont, Geny M. M. Groothuis, Mirjam Luijten, Erik H.J. Danen, Marjo de Graauw, John H.N. Meerman, Bob van de Water	2014	71
10	Quantitative High Content Imaging of Cellular Adaptive Stress Response Pathways in Toxicity for Chemical Safety Assessment Chemical Research in Toxicology ·Steven Wink, Steven Hiemstra, Suzanna Huppelschoten, Erik H.J. Danen, Marije Niemeijer, Giel Hendriks, Harry Vrieling, Bram Herpers, Bob van de Water	2014	66
11	The Golgi Comprises a Paired Stack that Is Separated at G2 by Modulation of the Actin Cytoskeleton through Abi and Scar/WAVE Developmental Cell ·Vangelis Kondylis, Hezder E. van Nispen tot Pannerden, Bram Herpers, Florence Friggi‐Grelin, Cathérine Rabouille	2007	63
12	Differential range and activity of various forms of the Hedgehog protein BMC Developmental Biology ·Rebecca J. Dawber, Stephen Hebbes, Bram Herpers, France Docquier, Marcel van den Heuvel	2005	57
13	Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells British Journal of Cancer ·Jolieke G. van Oosterwijk, Maayke A.J.H. van Ruler, Inge H. Briaire‐de Bruijn, Bram Herpers, Hans Gelderblom, Bob van de Water, Judith V.M.G. Bovée	2013	53
14	High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities Archives of Toxicology ·Steven Wink, Steven Hiemstra, Bram Herpers, Bob van de Water	2016	50
15	Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity Archives of Toxicology ·Bram Herpers, Steven Wink, Lisa Fredriksson, Zi Di, Giel Hendriks, Harry Vrieling, Hans de Bont, Bob van de Water	2015	48
16	AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver Archives of Toxicology ·Mackenzie Hadi, Sanja Dragović, Rachel van Swelm, Bram Herpers, Bob van de Water, Frans G. M. Rüssel, Jan N. M. Commandeur, Geny M. M. Groothuis	2012	42
17	Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling Molecular Cancer ·Alan M. Sandercock, Steven Rust, Sandrine Guillard, Kris F. Sachsenmeier, Nick Holoweckyj, Carl Hay, Matt Flynn, Qihui Huang, Kuan Yan, Bram Herpers, Leo Price, Jo Soden, Jim Freeth, Lutz Jermutus, Robert E. Hollingsworth, Ralph Minter	2015	35
18	New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids Archives of Toxicology ·Daniela Rodrigues, Terezinha de Souza, Luke Coyle, Matteo Piazza, Bram Herpers, Sofia Ferreira, Mian Zhang, Johanna Vappiani, Daniel C. Sévin, Attila Gábor, Anthony Lynch, Seung‐Wook Chung, Julio Sáez-Rodríguez, Danyel Jennen, Jos Kleinjans, Theo M. de Kok	2021	35
19	Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility Antibodies ·Tero Satomaa, Henna Pynnönen, Anja Vilkman, Titta Kotiranta, Virve Pitkänen, Annamari Heiskanen, Bram Herpers, Leo Price, Jari Helin, Juhani Saarinen	2018	35
20	Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening PLoS ONE ·Zi Di, Bram Herpers, Lisa Fredriksson, Kuan Yan, Bob van de Water, Fons J. Verbeek, John H.N. Meerman	2012	29

About Bram Herpers

Bram Herpers is a scholar working on Pharmacology, Oncology, Immunology and Allergy, Nephrology and Cancer Research, having authored 34 papers that have together received 1.6k indexed citations. Recurring topics across this work include Cancer Cells and Metastasis (8 papers), 3D Printing in Biomedical Research (7 papers), Drug-Induced Hepatotoxicity and Protection (6 papers), Colorectal Cancer Treatments and Studies (3 papers), Computational Drug Discovery Methods (3 papers), RNA Research and Splicing (3 papers), Chemotherapy-induced organ toxicity mitigation (3 papers) and Cell death mechanisms and regulation (3 papers). The work is most often cited by research in Pharmacology (214 citations), Hepatology (165 citations), Cell Biology (244 citations), Molecular Biology (763 citations) and Cancer Research (151 citations). Bram Herpers has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Bob van de Water, Cathérine Rabouille, Jan N. M. Commandeur, Leo Price, Michiel W. den Braver, Sreenivasa Ramaiahgari, Valeska Terpstra, Lisa Fredriksson, Steven Wink and Giulia Benedetti. Their work appears in journals such as Archives of Toxicology, Cancer Research, International Journal of Molecular Sciences, Annals of Oncology and Developmental Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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