A. Middleton

1.8k citations

33 papers · 818 indexed · h-index 15

Impact in

Chemical Health and Safety top 10%
Plant Science top 10%
- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Light effects on plants

Papers in ⓘ

Molecular Biology 14
- Plant Reproductive Biology 4
- Gene Regulatory Network Analysis 4
Computational Theory and Mathematics 8
- Computational Drug Discovery Methods 8

Co-authors: Markus R. Owen (4 shared papers)John R. King (7 shared papers)Malcolm J. Bennett (3 shared papers)Paul L. Carmichael (7 shared papers)Susana Úbeda-Tomás (2 shared papers)Shuangqing Peng (3 shared papers)Qiang Zhang (3 shared papers)Jin Li (3 shared papers)
Journals: Toxicology in Vitro (3 papers)Toxicological Sciences (3 papers)Toxicology Letters (3 papers)Journal of Theoretical Biology (2 papers)Toxicology (2 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

A. Middleton

27 papers receiving 806 citations

Peers

Countries citing papers authored by A. Middleton

Since Specialization

Citations

This map shows the geographic impact of A. Middleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Middleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Middleton more than expected).

Fields of papers citing papers by A. Middleton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Middleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Middleton. The network helps show where A. Middleton may publish in the future.

Co-authors

The 25 scholars most cited alongside A. Middleton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with A. Middleton Line = papers co-authored together A. Middleton links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 33 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway Toxicology in Vitro ·Jian Yin, Jiabin Guo, Qiang Zhang, Lan Cui, Li Zhang, Tingfen Zhang, Jun Zhao, Jin Li, A. Middleton, Paul L. Carmichael, Shuangqing Peng	2018	165
2	Mathematical modeling elucidates the role of transcriptional feedback in gibberellin signaling Proceedings of the National Academy of Sciences ·A. Middleton, Susana Úbeda-Tomás, Jayne Griffiths, Tara J. Holman, Peter Hedden, Stephen G. Thomas, Andrew L. Phillips, Michael J. Holdsworth, Malcolm J. Bennett, John R. King, Markus R. Owen	2012	115
3	Growth-induced hormone dilution can explain the dynamics of plant root cell elongation Proceedings of the National Academy of Sciences ·Leah R. Band, Susana Úbeda-Tomás, Rosemary Dyson, A. Middleton, Charlie Hodgman, Markus R. Owen, Oliver E. Jensen, Malcolm J. Bennett, John R. King	2012	94
4	Bridging the Data Gap From in vitro Toxicity Testing to Chemical Safety Assessment Through Computational Modeling Frontiers in Public Health ·Qiang Zhang, Jin Li, A. Middleton, Sudin Bhattacharya, Rory B. Conolly	2018	63
5	Mathematical Modelling of the Aux/IAA Negative Feedback Loop Bulletin of Mathematical Biology ·A. Middleton, John R. King, Malcolm J. Bennett, Markus R. Owen	2010	51
6	A continuum approximation to an off-lattice individual-cell based model of cell migration and adhesion Journal of Theoretical Biology ·A. Middleton, Christian Fleck, Ramon Grima	2014	46
7	Identifying and Characterizing Stress Pathways of Concern for Consumer Safety in Next-Generation Risk Assessment Toxicological Sciences ·Sarah Hatherell, Maria Teresa Baltazar, Joe Reynolds, Paul L. Carmichael, Matthew Dent, Hequn Li, Stephanie Ryder, Andrew White, Paul Walker, A. Middleton	2020	45
8	Are Non-animal Systemic Safety Assessments Protective? A Toolbox and Workflow Toxicological Sciences ·A. Middleton, Joe Reynolds, S. Cable, Maria Teresa Baltazar, Hequn Li, Samantha Bevan, Paul L. Carmichael, Matthew Dent, Sarah Hatherell, Jade Houghton, Predrag Kukić, Mark Liddell, Sophie Malcomber, Beate Nicol, Benjamin Park, Hiral Patel, Sharon Scott, Chris Sparham, Paul Walker, Andrew White	2022	34
9	Modeling Regulatory Networks to Understand Plant Development: Small Is Beautiful The Plant Cell ·A. Middleton, Etienne Farcot, Markus R. Owen, Teva Vernoux	2012	27
10	Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non‐small cell lung cancer (NSCLC) cells The Journal of Pathology ·Benedikt Müller, Michael Bovet, Yi Yin, Damian Stichel, Mona Malz, Margarita González‐Vallinas, A. Middleton, Volker Ehemann, Jennifer Schmitt, Thomas Muley, Michael Meister, Esther Herpel, Stephan Singer, Arne Warth, Peter Schirmacher, Dirk Drasdo, Franziska Matthäus, Kai Breuhahn	2015	27
11	Data-Driven Modeling of Intracellular Auxin Fluxes Indicates a Dominant Role of the ER in Controlling Nuclear Auxin Uptake Cell Reports ·A. Middleton, Cristina Dal Bosco, Phillip Chlap, Robert Bensch, Hartmann Harz, Fugang Ren, Stefan Bergmann, Sabrina Wend, Wilfried Weber, Ken‐ichiro Hayashi, Matías D. Zurbriggen, Rainer Uhl, Olaf Ronneberger, Klaus Palme, Christian Fleck, Alexander Dovzhenko	2018	23
12	An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors npj Systems Biology and Applications ·Damian Stichel, A. Middleton, Benedikt Müller, Sofia Depner, Ursula Klingmüller, Kai Breuhahn, Franziska Matthäus	2017	20
13	Next generation risk assessment (NGRA): Bridging in vitro points-of-departure to human safety assessment using physiologically-based kinetic (PBK) modelling – A case study of doxorubicin with dose metrics considerations Toxicology in Vitro ·Hequn Li, Haitao Yuan, A. Middleton, Jin Li, Beate Nicol, Paul L. Carmichael, Jiabin Guo, Shuangqing Peng, Qiang Zhang	2021	17
14	Flutamide Induces Hepatic Cell Death and Mitochondrial Dysfunction via Inhibition of Nrf2‐Mediated Heme Oxygenase‐1 Oxidative Medicine and Cellular Longevity ·Li Zhang, Jiabin Guo, Qiang Zhang, Wei Zhou, Jin Li, Jian Yin, Lan Cui, Tingfen Zhang, Jun Zhao, Paul L. Carmichael, A. Middleton, Shuangqing Peng	2018	17
15	Exploring the effects of experimental parameters and data modeling approaches on in vitro transcriptomic point-of-departure estimates Toxicology ·Joshua Harrill, Logan J. Everett, Derik E. Haggard, Joseph L. Bundy, Clinton Willis, Imran Shah, Katie Paul Friedman, Danilo Basili, A. Middleton, Richard Judson	2023	15
16	Sources of off-types in pedigreed seed of common spring wheat Canadian Journal of Plant Science ·Pierre Hucl, M. A. Matus‐Cádiz, A. S. Sahota, A. Middleton, D. O. Mooney, J. L. Maruschak	2004	9
17	A (Y;17) translocation in a fibroblast culture from a female with 46 chromosomes Cytogenetic and Genome Research ·J.M. Rary, A. Middleton, R.A. Mulivor, A.E. Greene, L.L. Coriell	1979	9
18	Latent Variables Capture Pathway-Level Points of Departure in High-Throughput Toxicogenomic Data Chemical Research in Toxicology ·Danilo Basili, Joe Reynolds, Jade Houghton, Sophie Malcomber, Bryant Chambers, Mark Liddell, Iris Müller, Andrew White, Imran Shah, Logan J. Everett, A. Middleton, Andreas Bender	2022	9
19	Bistability in a model of mesoderm and anterior mesendoderm specification in Xenopus laevis Journal of Theoretical Biology ·A. Middleton, John R. King, Matthew Loose	2009	7
20	Advancing systemic toxicity risk assessment: Evaluation of a NAM-based toolbox approach Toxicological Sciences ·S. Cable, Maria Teresa Baltazar, Fazila Bunglawala, Paul L. Carmichael, Leonardo Contreas, Matthew Dent, Jade Houghton, Predrag Kukić, Sophie Malcomber, Beate Nicol, Katarzyna R. Przybylak, Ans Punt, G. Reynolds, Joe Reynolds, Sharon Scott, Dawei Tang, A. Middleton	2024	6

About A. Middleton

A. Middleton is a scholar working on Molecular Biology, Computational Theory and Mathematics, Small Animals, Plant Science and Health, Toxicology and Mutagenesis, having authored 33 papers that have together received 818 indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (8 papers), Animal testing and alternatives (6 papers), Plant Molecular Biology Research (4 papers), Plant Reproductive Biology (4 papers), Effects and risks of endocrine disrupting chemicals (4 papers), Gene Regulatory Network Analysis (4 papers), Cellular Mechanics and Interactions (3 papers) and Plant nutrient uptake and metabolism (2 papers). The work is most often cited by research in Chemical Health and Safety (7 citations), Plant Science (335 citations), Small Animals (63 citations), Modeling and Simulation (39 citations) and Biophysics (38 citations). A. Middleton has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Markus R. Owen, John R. King, Malcolm J. Bennett, Paul L. Carmichael, Susana Úbeda-Tomás, Shuangqing Peng, Qiang Zhang, Jin Li, Jiabin Guo and Christian Fleck. Their work appears in journals such as Toxicology in Vitro, Toxicological Sciences, Toxicology Letters, Journal of Theoretical Biology and Toxicology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact