Steven M. Sine

13.4k citations

161 papers · 10.8k indexed · 2 hit papers · h-index 61

Cellular and Molecular Neuroscience top 0.5%
- Neuroscience and Neuropharmacology Research 15
Molecular Biology top 0.5%
- Ion channel regulation and function 120
- Nicotinic Acetylcholine Receptors Study 116
- Receptor Mechanisms and Signaling 71
Neurology top 0.5%
- Myasthenia Gravis and Thymoma 32
Insect Science top 0.5%
- Insect and Pesticide Research 14
Cell Biology top 1%
- Cellular transport and secretion 14
Pharmacology
- Cholinesterase and Neurodegenerative Diseases 13

Co-authors: Andrew G. Engel Palmer Taylor F.J. Sigworth Kinji Ohno Cecilia Bouzat Joe Henry Steinbach Hailong Wang Nina Bren
Cited by: Cellular and Molecular Neuroscience Molecular Biology Neurology
Journals: Nature (4 papers)Science (2 papers)Cell (2 papers)
Partner nations: United States Argentina United Kingdom

In The Last Decade

Steven M. Sine

159 papers receiving 10.6k citations

Hit Papers

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Peers

Countries citing papers authored by Steven M. Sine

Since Specialization

Citations

This map shows the geographic impact of Steven M. Sine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven M. Sine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven M. Sine more than expected).

Fields of papers citing papers by Steven M. Sine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven M. Sine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven M. Sine. The network helps show where Steven M. Sine may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Steven M. Sine, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Steven M. Sine Line = papers co-authored together Steven M. Sine links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Ion transport in muscle acetylcholine receptor maintained by conserved salt bridges between the pore and lipid membrane Proceedings of the National Academy of Sciences ·Lina Alhalhooly,Steven M. Sine	2024	1
2	Functional α7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics American Journal of Physiology-Lung Cellular and Molecular Physiology ·Latifa Khalfaoui,Nuriya Mukhtasimova,Brian M. Kelley,Natalya M. Wells,Jacob J. Teske,B. Roos,Niyati A. Borkar,Emily Zhang,Steven M. Sine,Y. S. Prakash,Christina M. Pabelick	2023	6
3	Nicotinic receptors in airway disease American Journal of Physiology-Lung Cellular and Molecular Physiology ·Niyati A. Borkar,Michael A. Thompson,Colleen M. Bartman,Latifa Khalfaoui,Steven M. Sine,Venkatachalem Sathish,Y. S. Prakash,Christina M. Pabelick	2023	4
4	Mechanism of calcium potentiation of the α7 nicotinic acetylcholine receptor The Journal of General Physiology ·Kathiresan Natarajan,Nuriya Mukhtasimova,Jeremías Corradi,Matías Lasala,Cecilia Bouzat,Steven M. Sine	2020	14
5	Stoichiometry for drug potentiation of a pentameric ion channel Proceedings of the National Academy of Sciences ·Corrie J.B. daCosta,Steven M. Sine	2013	23
6	Nicotinic Receptor Transduction Zone: Invariant Arginine Couples to Multiple Electron-Rich Residues Biophysical Journal ·Nuriya Mukhtasimova,Steven M. Sine	2013	25
7	Binding to Gating Transduction in Nicotinic Receptors: Cys-Loop Energetically Couples to Pre-M1 and M2–M3 Regions Journal of Neuroscience ·Won Yong Lee,Chris R. Free,Steven M. Sine	2009	85
8	On the Origin of Ion Selectivity in the Cys-Loop Receptor Family Journal of Molecular Neuroscience ·Steven M. Sine,Hailong Wang,Scott B. Hansen,Palmer Taylor	2009	22
9	Detection and trapping of intermediate states priming nicotinic receptor channel opening Nature ·Nuriya Mukhtasimova,Won Yong Lee,Hailong Wang,Steven M. Sine	2009	177
10	An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance Journal of Biological Chemistry ·Scott B. Hansen,Hailong Wang,Palmer Taylor,Steven M. Sine	2008	53
11	Congenital myasthenia–related AChR δ subunit mutation interferes with intersubunit communication essential for channel gating Journal of Clinical Investigation ·Xin‐Ming Shen,Taku Fukuda,Kinji Ohno,Steven M. Sine,Andrew G. Engel	2008	41
12	Nanosecond-Timescale Conformational Dynamics of the Human α7 Nicotinic Acetylcholine Receptor Biophysical Journal ·Xiaolin Cheng,Ivaylo Ivanov,Hailong Wang,Steven M. Sine,J. Andrew McCammon	2007	57
13	Targeted Molecular Dynamics Study of C-Loop Closure and Channel Gating in Nicotinic Receptors PLoS Computational Biology ·Xiaolin Cheng,Hailong Wang,Barry J. Grant,Steven M. Sine,J. Andrew McCammon	2006	105
14	Principal pathway coupling agonist binding to channel gating in nicotinic receptors Nature ·Won Yong Lee,Steven M. Sine	2005	239
15	Toward Atomic-Scale Understanding of Ligand Recognition in the Muscle Nicotinic Receptor Current Medicinal Chemistry ·Steven M. Sine,Hailong Wang,Fan Gao	2004	7
16	Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating Journal of Clinical Investigation ·Xin‐Ming Shen,Kinji Ohno,Akira Tsujino,Joan M. Brengman,Monique Gingold,Steven M. Sine,Andrew G. Engel	2003	60
17	Novel Modulation of Neuronal Nicotinic Acetylcholine Receptors by Association with the Endogenous Prototoxin lynx1 Neuron ·Inés Ibáñez-Tallon,Julie M. Miwa,Hailong Wang,Niels C. Adams,Gregg W. Crabtree,Steven M. Sine,Nathaniel Heintz	2002	163
18	Subunit-Selective Contribution to Channel Gating of the M4 Domain of the Nicotinic Receptor Biophysical Journal ·Cecilia Bouzat,Fernanda Gumilar,María del Carmen Esandi,Steven M. Sine	2002	46
19	Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors Neuron ·Cecilia Bouzat,Nina Bren,Steven M. Sine	1994	132
20	Functional consequences of agonist-mediated state transitions in the cholinergic receptor Federation Proceedings ·Steven M. Sine,Palmer Taylor	1979	52

About Steven M. Sine

Steven M. Sine is a scholar working on Molecular Biology, Neurology and Cellular and Molecular Neuroscience, having authored 161 papers that have together received 10.8k indexed citations. Recurring topics across this work include Ion channel regulation and function (120 papers), Nicotinic Acetylcholine Receptors Study (116 papers), Receptor Mechanisms and Signaling (71 papers), Myasthenia Gravis and Thymoma (32 papers), Neuroscience and Neuropharmacology Research (15 papers), Insect and Pesticide Research (14 papers), Cellular transport and secretion (14 papers) and Cholinesterase and Neurodegenerative Diseases (13 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (2.9k citations), Molecular Biology (9.6k citations) and Neurology (1.6k citations). Steven M. Sine has collaborated with scholars based in United States, Argentina and United Kingdom. Frequent co-authors include Andrew G. Engel, Palmer Taylor, F.J. Sigworth, Kinji Ohno, Cecilia Bouzat, Joe Henry Steinbach, Hailong Wang, Nina Bren, Won Yong Lee and Xin‐Ming Shen. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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