Steven M. Sine

13.4k total citations · 2 hit papers
161 papers, 10.8k citations indexed

About

Steven M. Sine is a scholar working on Molecular Biology, Neurology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Steven M. Sine has authored 161 papers receiving a total of 10.8k indexed citations (citations by other indexed papers that have themselves been cited), including 152 papers in Molecular Biology, 32 papers in Neurology and 30 papers in Cellular and Molecular Neuroscience. Recurrent topics in Steven M. Sine's work include Ion channel regulation and function (120 papers), Nicotinic Acetylcholine Receptors Study (116 papers) and Receptor Mechanisms and Signaling (71 papers). Steven M. Sine is often cited by papers focused on Ion channel regulation and function (120 papers), Nicotinic Acetylcholine Receptors Study (116 papers) and Receptor Mechanisms and Signaling (71 papers). Steven M. Sine collaborates with scholars based in United States, Argentina and United Kingdom. Steven M. Sine's co-authors include Andrew G. Engel, Palmer Taylor, F.J. Sigworth, Kinji Ohno, Cecilia Bouzat, Joe Henry Steinbach, Hailong Wang, Nina Bren, Won Yong Lee and Xin‐Ming Shen and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Steven M. Sine

159 papers receiving 10.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Data transformations for improved display and fitting of single-channel dwell time histograms

1987 736 citations Steven M. Sine et al. Biophysical Journal profile →
Congenital myasthenic syndromes: pathogenesis, diagnosis, and treatment

2015 361 citations Andrew G. Engel, Xin‐Ming Shen et al. profile →

Peers

Countries citing papers authored by Steven M. Sine

Since Specialization

Citations

This map shows the geographic impact of Steven M. Sine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven M. Sine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven M. Sine more than expected).

Fields of papers citing papers by Steven M. Sine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven M. Sine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven M. Sine. The network helps show where Steven M. Sine may publish in the future.

Co-authorship network of co-authors of Steven M. Sine

This figure shows the co-authorship network connecting the top 25 collaborators of Steven M. Sine. A scholar is included among the top collaborators of Steven M. Sine based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven M. Sine. Steven M. Sine is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Ion transport in muscle acetylcholine receptor maintained by conserved salt bridges between the pore and lipid membrane 2024 ·Proceedings of the National Academy of Sciences ·(unknown), Steven M. Sine	1
2	Functional α7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics 2023 ·American Journal of Physiology-Lung Cellular and Molecular Physiology ·Latifa Khalfaoui, Nuriya Mukhtasimova, Brian M. Kelley, (unknown), Jacob J. Teske, (unknown), (unknown), Emily Zhang, Steven M. Sine, Y. S. Prakash, Christina M. Pabelick	6
3	Nicotinic receptors in airway disease 2023 ·American Journal of Physiology-Lung Cellular and Molecular Physiology ·(unknown), Michael A. Thompson, (unknown), Latifa Khalfaoui, Steven M. Sine, Venkatachalem Sathish, Y. S. Prakash, Christina M. Pabelick	4
4	Mechanism of calcium potentiation of the α7 nicotinic acetylcholine receptor 2020 ·The Journal of General Physiology ·Kathiresan Natarajan, Nuriya Mukhtasimova, Jeremías Corradi, (unknown), Cecilia Bouzat, Steven M. Sine	14
5	Stoichiometry for drug potentiation of a pentameric ion channel 2013 ·Proceedings of the National Academy of Sciences ·Corrie J.B. daCosta, Steven M. Sine	23
6	Nicotinic Receptor Transduction Zone: Invariant Arginine Couples to Multiple Electron-Rich Residues 2013 ·Biophysical Journal ·Nuriya Mukhtasimova, Steven M. Sine	25
7	Binding to Gating Transduction in Nicotinic Receptors: Cys-Loop Energetically Couples to Pre-M1 and M2–M3 Regions 2009 ·Journal of Neuroscience ·Won Yong Lee, (unknown), Steven M. Sine	85
8	On the Origin of Ion Selectivity in the Cys-Loop Receptor Family 2009 ·Journal of Molecular Neuroscience ·Steven M. Sine, Hailong Wang, Scott B. Hansen, Palmer Taylor	22
9	Detection and trapping of intermediate states priming nicotinic receptor channel opening 2009 ·Nature ·Nuriya Mukhtasimova, Won Yong Lee, Hailong Wang, Steven M. Sine	177
10	An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance 2008 ·Journal of Biological Chemistry ·Scott B. Hansen, Hailong Wang, Palmer Taylor, Steven M. Sine	53
11	Congenital myasthenia–related AChR δ subunit mutation interferes with intersubunit communication essential for channel gating 2008 ·Journal of Clinical Investigation ·Xin‐Ming Shen, Taku Fukuda, Kinji Ohno, Steven M. Sine, Andrew G. Engel	41
12	Nanosecond-Timescale Conformational Dynamics of the Human α7 Nicotinic Acetylcholine Receptor 2007 ·Biophysical Journal ·Xiaolin Cheng, Ivaylo Ivanov, Hailong Wang, Steven M. Sine, J. Andrew McCammon	57
13	Targeted Molecular Dynamics Study of C-Loop Closure and Channel Gating in Nicotinic Receptors 2006 ·PLoS Computational Biology ·Xiaolin Cheng, Hailong Wang, Barry J. Grant, Steven M. Sine, J. Andrew McCammon	105
14	Principal pathway coupling agonist binding to channel gating in nicotinic receptors 2005 ·Nature ·Won Yong Lee, Steven M. Sine	239
15	Toward Atomic-Scale Understanding of Ligand Recognition in the Muscle Nicotinic Receptor 2004 ·Current Medicinal Chemistry ·Steven M. Sine, Hailong Wang, Fan Gao	7
16	Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating 2003 ·Journal of Clinical Investigation ·Xin‐Ming Shen, Kinji Ohno, Akira Tsujino, Joan M. Brengman, Monique Gingold, Steven M. Sine, Andrew G. Engel	60
17	Novel Modulation of Neuronal Nicotinic Acetylcholine Receptors by Association with the Endogenous Prototoxin lynx1 2002 ·Neuron ·Inés Ibáñez-Tallon, Julie M. Miwa, Hailong Wang, Niels C. Adams, Gregg W. Crabtree, Steven M. Sine, Nathaniel Heintz	163
18	Subunit-Selective Contribution to Channel Gating of the M4 Domain of the Nicotinic Receptor 2002 ·Biophysical Journal ·Cecilia Bouzat, Fernanda Gumilar, María del Carmen Esandi, Steven M. Sine	46
19	Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors 1994 ·Neuron ·Cecilia Bouzat, Nina Bren, Steven M. Sine	132
20	Functional consequences of agonist-mediated state transitions in the cholinergic receptor 1979 ·Federation Proceedings ·Steven M. Sine, Palmer Taylor	52

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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