Jürgen Scheller

21.4k total citations · 5 hit papers
195 papers, 16.7k citations indexed

About

Jürgen Scheller is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Jürgen Scheller has authored 195 papers receiving a total of 16.7k indexed citations (citations by other indexed papers that have themselves been cited), including 111 papers in Oncology, 107 papers in Immunology and 41 papers in Molecular Biology. Recurrent topics in Jürgen Scheller's work include Cytokine Signaling Pathways and Interactions (87 papers), Immune Cell Function and Interaction (27 papers) and Toxin Mechanisms and Immunotoxins (24 papers). Jürgen Scheller is often cited by papers focused on Cytokine Signaling Pathways and Interactions (87 papers), Immune Cell Function and Interaction (27 papers) and Toxin Mechanisms and Immunotoxins (24 papers). Jürgen Scheller collaborates with scholars based in Germany, United States and United Kingdom. Jürgen Scheller's co-authors include Stefan Rose‐John, Athena Chalaris, Dirk Schmidt‐Arras, Christoph Garbers, Simon A. Jones, Joachim Grötzinger, Udo Conrad, Doreen M. Floß, Georg H. Waetzig and Lars Eckmann and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Jürgen Scheller

191 papers receiving 16.4k citations

Hit Papers

The pro- and anti-inflammatory properties of the cytokine... 2006 2026 2012 2019 2011 2009 2006 2011 2023 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The pro- and anti-inflammatory properties of the cytokine interleukin-6
    2011 2.5k citations Jürgen Scheller, Athena Chalaris et al. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research profile →
  2. IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
    2009 1.7k citations Jürgen Scheller, Stefan Rose‐John et al. profile →
  3. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer
    2006 529 citations Stefan Rose‐John, Jürgen Scheller et al. profile →
  4. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
    2011 528 citations Simon A. Jones, Jürgen Scheller et al. Journal of Clinical Investigation profile →
  5. Targeting IL-6 trans-signalling: past, present and future prospects
    2023 271 citations Stefan Rose‐John, Brendan J. Jenkins et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jürgen Scheller Germany 59 6.4k 5.7k 5.0k 1.8k 1.7k 195 16.7k
Simon A. Jones United Kingdom 66 7.9k 1.2× 5.1k 0.9× 3.7k 0.7× 1.9k 1.1× 1.3k 0.8× 160 16.7k
Tadashi Matsuda Japan 52 5.2k 0.8× 4.8k 0.9× 5.0k 1.0× 1.1k 0.6× 1.4k 0.8× 276 14.6k
Masashi Narazaki Japan 44 5.0k 0.8× 4.9k 0.9× 4.1k 0.8× 1.4k 0.8× 1.1k 0.6× 92 14.2k
Angela Santoni Italy 73 12.2k 1.9× 5.2k 0.9× 5.2k 1.0× 1.5k 0.8× 1.3k 0.7× 406 19.9k
Lionel B. Ivashkiv United States 72 9.7k 1.5× 4.5k 0.8× 6.5k 1.3× 1.6k 0.9× 2.1k 1.2× 174 18.2k
Thomas Giese Germany 67 7.6k 1.2× 3.4k 0.6× 4.3k 0.8× 2.2k 1.2× 1.2k 0.7× 246 15.4k
Yang Liu China 84 11.4k 1.8× 7.1k 1.3× 8.8k 1.7× 1.6k 0.9× 3.0k 1.7× 707 24.4k
Hui Wang China 62 3.7k 0.6× 2.7k 0.5× 6.7k 1.3× 2.1k 1.2× 2.0k 1.2× 708 16.0k
Emilio Hirsch Italy 73 5.4k 0.8× 2.9k 0.5× 9.6k 1.9× 1.2k 0.6× 1.5k 0.9× 297 19.0k
Etty Benveniste United States 80 7.5k 1.2× 3.8k 0.7× 6.0k 1.2× 1.3k 0.7× 2.2k 1.3× 233 18.5k

Countries citing papers authored by Jürgen Scheller

Since Specialization
Citations

This map shows the geographic impact of Jürgen Scheller's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jürgen Scheller with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jürgen Scheller more than expected).

Fields of papers citing papers by Jürgen Scheller

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jürgen Scheller. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jürgen Scheller. The network helps show where Jürgen Scheller may publish in the future.

Co-authorship network of co-authors of Jürgen Scheller

This figure shows the co-authorship network connecting the top 25 collaborators of Jürgen Scheller. A scholar is included among the top collaborators of Jürgen Scheller based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jürgen Scheller. Jürgen Scheller is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Becker, Stefan, Jürgen Rödel, Jürgen Scheller, et al.. (2025). Taming interleukin‐12: Engineering of bispecific antibody‐based IL‐12 mimetics with biased agonism capacities. Protein Science. 34(3). e70072–e70072. 4 indexed citations
2.
Scheller, Jürgen, et al.. (2024). Intratumoral Delivery of Genetically Engineered Anti-IL-6 Trans-signaling Therapeutics. Molecular Biotechnology. 67(7). 2696–2708. 1 indexed citations
3.
Liu, Xueqing, Hongyan Jiang, Jianfeng Zhao, et al.. (2024). A refined TTC assay precisely detects cardiac injury and cellular viability in the infarcted mouse heart. Scientific Reports. 14(1). 25214–25214. 2 indexed citations
4.
Behnke, Kristina, Philip Kirschner, Sonja Hartwig, et al.. (2024). Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes. Nature Communications. 15(1). 1076–1076. 7 indexed citations
5.
Castorina, Alessandro, Jürgen Scheller, Kevin A. Keay, et al.. (2024). Increased Expression of the Neuropeptides PACAP/VIP in the Brain of Mice with CNS Targeted Production of IL-6 Is Mediated in Part by Trans-Signalling. International Journal of Molecular Sciences. 25(17). 9453–9453. 3 indexed citations
6.
Alter, Christina, Julia Hesse, Zhaoping Ding, et al.. (2023). IL-6 in the infarcted heart is preferentially formed by fibroblasts and modulated by purinergic signaling. Journal of Clinical Investigation. 133(11). 34 indexed citations
7.
Lang, Alexander, et al.. (2023). CoCl 2 ‐triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299. FEBS Open Bio. 13(12). 2187–2199. 1 indexed citations
8.
Scheller, Jürgen, et al.. (2023). Exploring the landscape of synthetic IL‐6‐type cytokines. FEBS Journal. 291(10). 2030–2050. 6 indexed citations
9.
Matsumura, Fumio, et al.. (2021). Investigation of Fascin1, a Marker of Mature Dendritic Cells, Reveals a New Role for IL-6 Signaling in CCR7-Mediated Chemotaxis. The Journal of Immunology. 207(3). 938–949. 8 indexed citations
10.
Schwerd, Tobias, Stephen R.F. Twigg, Dominik Aschenbrenner, et al.. (2020). A variant in IL6ST with a selective IL-11 signaling defect in human and mouse. Bone Research. 8(1). 24–24. 21 indexed citations
11.
Lamertz, Larissa, Robin Polz, Paul Baran, et al.. (2018). Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses. Science Signaling. 11(550). 57 indexed citations
12.
Dewitz, Christin, Katja Möller‐Hackbarth, Ahmad Trad, et al.. (2013). Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843(2). 275–287. 32 indexed citations
13.
Dewitz, Christin, Katja Möller‐Hackbarth, Jürgen Scheller, et al.. (2012). Effects of Blockade of Peripheral Interleukin-6 Trans-Signaling on Hippocampus-Dependent and Independent Memory in Mice. Journal of Interferon & Cytokine Research. 33(5). 254–260. 7 indexed citations
14.
Barkhausen, Tanja, Thomas Tschernig, Philip Rosenstiel, et al.. (2011). Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*. Critical Care Medicine. 39(6). 1407–1413. 127 indexed citations
15.
Bender, Markus, Sebastian Hofmann, David Stegner, et al.. (2010). Differentially regulated GPVI ectodomain shedding by multiple platelet–expressed proteinases. Blood. 116(17). 3347–3355. 98 indexed citations
16.
Jones, Gareth W., Rachel M. McLoughlin, Victoria J. Hammond, et al.. (2010). Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells. The Journal of Immunology. 184(4). 2130–2139. 147 indexed citations
17.
Rabe, Björn, et al.. (2009). Interleukin-6 Trans-Signaling Regulates Glycogen Consumption After d -Galactosamine-Induced Liver Damage. Journal of Interferon & Cytokine Research. 29(11). 711–718. 13 indexed citations
18.
19.
Nowell, Mari A., Anwen S. Williams, Jürgen Scheller, et al.. (2009). Therapeutic Targeting of IL-6 Trans Signaling Counteracts STAT3 Control of Experimental Inflammatory Arthritis. The Journal of Immunology. 182(1). 613–622. 175 indexed citations
20.
Fantini, Massimo Claudio, Clemens Neufert, Alexei Nikolaev, et al.. (2007). Cutting Edge: Trans- Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25− T Cells. The Journal of Immunology. 179(4). 2041–2045. 189 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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