Simon Knott

4.5k citations

44 papers · 2.1k indexed · h-index 23

Impact in

Cancer Research top 5%
Molecular Biology top 5%
- DNA Repair Mechanisms
- Genomics and Chromatin Dynamics
- CRISPR and Genetic Engineering
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- RNA Research and Splicing

Papers in ⓘ

Cancer Research 11
- Cancer Genomics and Diagnostics 4
Oncology 15
- Cancer Immunotherapy and Biomarkers 8

Co-authors: Gregory J. Hannon (8 shared papers)Oscar M. Aparicio (8 shared papers)Christopher J. Viggiani (6 shared papers)Simon Tavaré (6 shared papers)Jonathan J. Ipsaro (1 shared paper)Astrid D. Haase (1 shared paper)Leemor Joshua‐Tor (1 shared paper)Nicolas Erard (5 shared papers)
Journals: Xenobiotica (4 papers)Nature (3 papers)Cancer Research (3 papers)Genes & Development (3 papers)Cell Reports (2 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Simon Knott

43 papers receiving 2.1k citations

Peers

Countries citing papers authored by Simon Knott

Since Specialization

Citations

This map shows the geographic impact of Simon Knott's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Knott with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Knott more than expected).

Fields of papers citing papers by Simon Knott

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Knott. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Knott. The network helps show where Simon Knott may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon Knott, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon Knott Line = papers co-authored together Simon Knott links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 44 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis Nature ·Elvin Wagenblast, Mar Soto, Sara Gutiérrez-Ángel, Christina Hartl, Annika L. Gable, Ashley R. Maceli, Nicolas Erard, Alissa M. Williams, Sun Y. Kim, Steffen Dickopf, J. Chuck Harrell, Andrew D. Smith, Charles M. Perou, John E. Wilkinson, Gregory J. Hannon, Simon Knott	2015	310
2	The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis Nature ·Jonathan J. Ipsaro, Astrid D. Haase, Simon Knott, Leemor Joshua‐Tor, Gregory J. Hannon	2012	253
3	Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth Cell Metabolism ·Abigail S. Krall, Peter J. Mullen, Felicia Surjono, Milica Momcilovic, E. Schmid, Christopher J. Halbrook, Apisadaporn Thambundit, Steven D. Mittelman, Costas A. Lyssiotis, David B. Shackelford, Simon Knott, Heather R. Christofk	2021	177
4	Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae Cell ·Simon Knott, Jared M. Peace, A. Zachary Ostrow, Yan Gan, Alexandra E. Rex, Christopher J. Viggiani, Simon Tavaré, Oscar M. Aparicio	2012	156
5	Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae Genes & Development ·Simon Knott, Christopher J. Viggiani, Simon Tavaré, Oscar M. Aparicio	2009	105
6	An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer Nature Communications ·Kenneth Gouin, Nathan Ing, Jasmine Plummer, Charles J. Rosser, Bassem Ben Cheikh, Catherine Oh, Stephanie S. Chen, Keith Syson Chan, Hideki Furuya, Warren G. Tourtellotte, Simon Knott, Dan Theodorescu	2021	103
7	The level of origin firing inversely affects the rate of replication fork progression The Journal of Cell Biology ·Yuan Zhong, Tittu Thomas Nellimoottil, Jared M. Peace, Simon Knott, Sandra K. Villwock, Janis M. Yee, Jeffrey M. Jancuska, Sanket Rege, Marianne Tecklenburg, Robert A. Sclafani, Simon Tavaré, Oscar M. Aparicio	2013	79
8	Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae Genes & Development ·Shawn J. Szyjka, Jennifer G. Aparicio, Christopher J. Viggiani, Simon Knott, Weihong Xu, Simon Tavaré, Oscar M. Aparicio	2008	74
9	Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases Nature Genetics ·Johannes G. Reiter, Wei‐Ting Hung, I‐Hsiu Lee, Shriya V. Nagpal, Peter Giunta, Sebastian Degner, Gang Liu, Emma C. E. Wassenaar, William R. Jeck, Martin S. Taylor, Alexander Farahani, Hetal D. Marble, Simon Knott, Onno Kranenburg, Jochen K. Lennerz, Kamila Naxerova	2020	70
10	A Computational Algorithm to Predict shRNA Potency Molecular Cell ·Simon Knott, Ashley R. Maceli, Nicolas Erard, Kenneth Chang, Krista Marran, Xin Zhou, Assaf Gordon, Osama E. Demerdash, Elvin Wagenblast, Sun Y. Kim, Christof Fellmann, Gregory J. Hannon	2014	69
11	lncRNA requirements for mouse acute myeloid leukemia and normal differentiation eLife ·M. Joaquina Delás, Leah R. Sabin, Egor Dolzhenko, Simon Knott, Ester Munera-Maravilla, Benjamin T. Jackson, Sophia A. Wild, Tatjana Kovačević, Eva Maria Stork, Meng Zhou, Nicolas Erard, Emily Lee, David R. Kelley, Mareike Roth, Inês Amorim Monteiro Barbosa, Johannes Zuber, John L. Rinn, Andrew D. Smith, Gregory J. Hannon	2017	60
12	Species differences in blood profiles, metabolism and excretion of ¹⁴ C-propofol after intravenous dosing to rat, dog and rabbit Xenobiotica ·Peter J. Simons, I. D. Cockshott, Elaine Douglas, Emma Gordon, Simon Knott, R. J. Ruane	1991	59
13	Dynamic, mating-induced gene expression changes in female head and brain tissues of Drosophila melanogaster BMC Genomics ·Justin E Dalton, Tanvi S Kacheria, Simon Knott, Matthew S. Lebo, Allison Nishitani, Laura E. Sanders, Emma J Stirling, Ari Winbush, Michelle N Arbeitman	2010	51
14	Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains BMC Genomics ·Justin E Dalton, Justin M. Fear, Simon Knott, Bruce S. Baker, Lauren M. McIntyre, Michelle N Arbeitman	2013	50
15	Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors OncoImmunology ·Erika J. Crosby, Jun-Ping Wei, Xiao Yang, Gangjun Lei, Tao Wang, Cong-Xiao Liu, Pankaj Agarwal, Alan J. Korman, Michael A. Morse, Kenneth Gouin, Simon Knott, H. Kim Lyerly, Zachary C. Hartman	2017	46
16	RNF17 blocks promiscuous activity of PIWI proteins in mouse testes Genes & Development ·Kaja A. Wasik, Oliver H. Tam, Simon Knott, Ilaria Falciatori, Molly Hammell, Vasily V. Vagin, Gregory J. Hannon	2015	44
17	TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer Proceedings of the National Academy of Sciences ·Neeraj Agarwal, Sébastien Rinaldetti, Bassem Ben Cheikh, Qiong Zhou, Evan P. Hass, Robert T. Jones, Molishree Joshi, Daniel V. LaBarbera, Simon Knott, Thomas R. Cech, Dan Theodorescu	2021	42
18	Fkh1 and Fkh2 Bind Multiple Chromosomal Elements in the S. cerevisiae Genome with Distinct Specificities and Cell Cycle Dynamics PLoS ONE ·A. Zachary Ostrow, Tittu Thomas Nellimoottil, Simon Knott, Catherine A. Fox, Simon Tavaré, Oscar M. Aparicio	2014	40
19	Genome-Wide Network Analysis Reveals the Global Properties of IFN-β Immediate Transcriptional Effects in Humans The Journal of Immunology ·Guy Haskin Fernald, Simon Knott, Andrew R. Pachner, Stacy J. Caillier, Kavitha Narayan, Jorge R. Oksenberg, Parvin Mousavi, Sergio E. Baranzini	2007	33
20	A CRISPR Resource for Individual, Combinatorial, or Multiplexed Gene Knockout Molecular Cell ·Nicolas Erard, Simon Knott, Gregory J. Hannon	2017	33

About Simon Knott

Simon Knott is a scholar working on Cancer Research, Oncology, Anesthesiology and Pain Medicine, Molecular Biology and Biochemistry, having authored 44 papers that have together received 2.1k indexed citations. Recurring topics across this work include Cancer Immunotherapy and Biomarkers (8 papers), DNA Repair Mechanisms (7 papers), Genomics and Chromatin Dynamics (6 papers), Epigenetics and DNA Methylation (5 papers), Fungal and yeast genetics research (4 papers), CRISPR and Genetic Engineering (4 papers), Cancer Genomics and Diagnostics (4 papers) and RNA modifications and cancer (4 papers). The work is most often cited by research in Cancer Research (447 citations), Molecular Biology (1.5k citations), Oncology (424 citations), Aging (25 citations) and Anesthesiology and Pain Medicine (73 citations). Simon Knott has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Gregory J. Hannon, Oscar M. Aparicio, Christopher J. Viggiani, Simon Tavaré, Jonathan J. Ipsaro, Astrid D. Haase, Leemor Joshua‐Tor, Nicolas Erard, Elvin Wagenblast and Jared M. Peace. Their work appears in journals such as Xenobiotica, Nature, Cancer Research, Genes & Development and Cell Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact