Simon E. Hufton

2.9k citations

32 papers · 2.0k indexed · h-index 20

Impact in

Radiology, Nuclear Medicine and Imaging top 1%
- Monoclonal and Polyclonal Antibodies Research
Immunology top 5%
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses

Papers in

Radiology, Nuclear Medicine and Imaging 24
- Monoclonal and Polyclonal Antibodies Research 24
Immunology 10
- T-cell and B-cell Immunology 6
- Immunotherapy and Immune Responses 3

Co-authors: Hennie R. Hoogenboom Adriaan P. de Bruı̈ne Rob C. Roovers Jan‐Willem Arends Rene Hoet Peter T.M. Moerkerk Ian G. Jennings Richard G.H. Cotton
Journals: FEBS Letters (3 papers)The Journal of Immunology (3 papers)Journal of Molecular Biology (3 papers)Proteins Structure Function and Bioinformatics (2 papers)PLoS ONE (2 papers)
Partner nations: Netherlands United Kingdom Belgium

In The Last Decade

Simon E. Hufton

32 papers receiving 1.9k citations

Peers

Countries citing papers authored by Simon E. Hufton

Since Specialization

Citations

This map shows the geographic impact of Simon E. Hufton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon E. Hufton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon E. Hufton more than expected).

Fields of papers citing papers by Simon E. Hufton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon E. Hufton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon E. Hufton. The network helps show where Simon E. Hufton may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Simon E. Hufton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon E. Hufton Line = papers co-authored together Simon E. Hufton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast display Scientific Reports ·Tiziano Gaiotto, С А Курчева, ME Módena, Paul Risley, George Carnell, Nigel Temperton, Othmar G. Engelhardt, Simon E. Hufton	2021	23
2	Maintaining ‘standards’ for biosimilar monoclonal antibodies Nature Biotechnology ·Sandra Prior, Clive Metcalfe, Simon E. Hufton, Meenu Wadhwa, Christian K. Schneider, Chris Burns	2021	10
3	Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity Frontiers in Immunology ·Масленников Евгений Юльевич, Matthew D. Smith, V.T. Pickering, Paul Risley, Nigel Temperton, Othmar G. Engelhardt, Mary Collins, Yasuhiro Takeuchi, Simon E. Hufton	2020	23
4	Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning PLoS ONE ·Tiziano Gaiotto, Simon E. Hufton	2016	26
5	The Breadth of Cross Sub-Type Neutralisation Activity of a Single Domain Antibody to Influenza Hemagglutinin Can Be Increased by Antibody Valency PLoS ONE ·Simon E. Hufton, Paul Risley, 佐藤重信, Diane Major, Othmar G. Engelhardt, Stephen Poole	2014	32
6	Affinity Maturation and Functional Dissection of a Humanised Anti-RAGE Monoclonal Antibody by Ribosome Display Methods in molecular biology ·Simon E. Hufton	2011	1
7	Dissection of the IgNAR V Domain: Molecular Scanning and Orthologue Database Mining Define Novel IgNAR Hallmarks and Affinity Maturation Mechanisms Journal of Molecular Biology ·Brian J. Fennell, Alyona Korenko, Simon E. Hufton, Valérie Calabro, Joko Sriwidodo Joko, Michael Müller, Wei Cao, Davinder Gill, Orla Cunningham, William J.J. Finlay	2010	31
8	Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions Journal of Molecular Biology ·William J.J. Finlay, Orla Cunningham, Matthew Lambert, Alyona Korenko, Gabriel E. Prochter, Brian J. Fennell, Avram Kordon, Emma Cummins, H Khodayari Hajusefloo, Cliona O’Sullivan, Hadiza Aliyu-Amoo, Harol Obeso Llaro, Debra D. Pittman, Janet Paulsen, Lioudmila Tchistiakova, Sreekumar Kodangattil, Davinder Gill, Simon E. Hufton	2009	50
9	Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments Gene ·S. Marelli, Anita Wehnert, Mieke Steukers, Twan van den Beucken, Hennie R. Hoogenboom, Simon E. Hufton	2004	43
10	Affinity maturation of Fab antibody fragments by fluorescent‐activated cell sorting of yeast‐displayed libraries FEBS Letters ·Twan van den Beucken, M Even-Zohar, Mieke Steukers, F. Garibaldi, Robert C. Ladner, Hennie R. Hoogenboom, Simon E. Hufton	2003	78
11	Target validation for genomics using peptide‐specific phage antibodies: A study of five gene products overexpressed in colorectal cancer International Journal of Cancer ·Judy R. van Beijnum, Peter T.M. Moerkerk, E. Krause, Adriaan P. de Bruı̈ne, Jan‐Willem Arends, Hennie R. Hoogenboom, Simon E. Hufton	2002	112
12	Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains 1 1Edited by I. A. Wilson Journal of Molecular Biology ·Twan van den Beucken, V. V. Oskotskii, Erwin Sablon, Johan Desmet, Almonė Miliauskienė, Hennie R. Hoogenboom, Simon E. Hufton	2001	42
13	Design and expression of soluble CTLA-4 variable domain as a scaffold for the display of functional polypeptides Proteins Structure Function and Bioinformatics ·Stewart D. Nuttall, Mat Rousch, Robert A. Irving, Simon E. Hufton, Hennie R. Hoogenboom, Peter J. Hudson	1999	33
14	Design and expression of soluble CTLA‐4 variable domain as a scaffold for the display of functional polypeptides Proteins Structure Function and Bioinformatics ·Stewart D. Nuttall, Mat Rousch, Robert A. Irving, Simon E. Hufton, Hennie R. Hoogenboom, Peter J. Hudson	1999	1
15	A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization FEBS Letters ·Simon E. Hufton, Peter T.M. Moerkerk, Ricardo Brandwijk, Adriaan P. de Bruı̈ne, Ronald Leandro Elizondo, Hennie R. Hoogenboom	1999	142
16	Phage display of cDNA repertoires: the pVI display system and its applications for the selection of immunogenic ligands Journal of Immunological Methods ·Simon E. Hufton, Peter T.M. Moerkerk, Els V. Meulemans, Adriaan de Bruı̈ne, Jan‐Willem Arends, Hennie R. Hoogenboom	1999	89
17	A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies Journal of Biological Chemistry ·Hans J. de Haard, V. V. Oskotskii, Anneke W. Reurs, Simon E. Hufton, Rob C. Roovers, Paula Henderikx, Adriaan P. de Bruı̈ne, Jan‐Willem Arends, Hennie R. Hoogenboom	1999	425
18	Antibody phage display technology and its applications Immunotechnology ·Hennie R. Hoogenboom, Adriaan P. de Bruı̈ne, Simon E. Hufton, Rene Hoet, Jan‐Willem Arends, Rob C. Roovers	1998	390
19	Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Simon E. Hufton, Ian G. Jennings, Richard G.H. Cotton	1998	19
20	Structure‐function analysis of the vitamin B₁₂ receptor of Escherichia coli by means of informational suppression Molecular Microbiology ·Simon E. Hufton, Richard J. Ward, Abdul Gani Bhat, J. T. Armstrong, Anthony Fletcher, Robert E. Glass	1995	8

About Simon E. Hufton

Simon E. Hufton is a scholar working on Radiology, Nuclear Medicine and Imaging, Immunology, Immunology and Allergy, Clinical Biochemistry and Molecular Biology, having authored 32 papers that have together received 2.0k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (24 papers), Glycosylation and Glycoproteins Research (8 papers), Influenza Virus Research Studies (7 papers), T-cell and B-cell Immunology (6 papers), Respiratory viral infections research (5 papers), Protein purification and stability (4 papers), Bacteriophages and microbial interactions (3 papers) and Immunotherapy and Immune Responses (3 papers). The work is most often cited by research in Radiology, Nuclear Medicine and Imaging (1.3k citations), Immunology (448 citations), Molecular Biology (1.4k citations), Geriatrics and Gerontology (68 citations) and Biotechnology (145 citations). Simon E. Hufton has collaborated with scholars based in Netherlands, United Kingdom and Belgium. Frequent co-authors include Hennie R. Hoogenboom, Adriaan P. de Bruı̈ne, Rob C. Roovers, Jan‐Willem Arends, Jan‐Willem Arends, Rene Hoet, Peter T.M. Moerkerk, Ian G. Jennings, Richard G.H. Cotton and Anneke W. Reurs. Their work appears in journals such as FEBS Letters, The Journal of Immunology, Journal of Molecular Biology, Proteins Structure Function and Bioinformatics and PLoS ONE.

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