Clive Metcalfe

2.2k total citations · 1 hit paper
39 papers, 1.9k citations indexed

About

Clive Metcalfe is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Clive Metcalfe has authored 39 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Molecular Biology, 14 papers in Oncology and 11 papers in Immunology. Recurrent topics in Clive Metcalfe's work include Metal complexes synthesis and properties (9 papers), Porphyrin Metabolism and Disorders (7 papers) and Hemoglobin structure and function (7 papers). Clive Metcalfe is often cited by papers focused on Metal complexes synthesis and properties (9 papers), Porphyrin Metabolism and Disorders (7 papers) and Hemoglobin structure and function (7 papers). Clive Metcalfe collaborates with scholars based in United Kingdom, United States and Germany. Clive Metcalfe's co-authors include Jim A. Thomas, Emma Lloyd Raven, P.C.E. Moody, Emma J. Murphy, Harry Adams, Andrea Gumiero, A. Neil Barclay, Michelle Webb, Ihtshamul Haq and Jaswir Basran and has published in prestigious journals such as Science, Journal of the American Chemical Society and Chemical Society Reviews.

In The Last Decade

Clive Metcalfe

39 papers receiving 1.9k citations

Hit Papers

Kinetically inert transition metal complexes that reversi... 2003 2026 2010 2018 2003 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Kinetically inert transition metal complexes that reversibly bind to DNA
    2003 678 citations Clive Metcalfe, Jim A. Thomas Chemical Society Reviews profile →

Peers

Clive Metcalfe
Qiong Wu China
Julie A. Woods United Kingdom
Diran Herebıan Germany
Anne M. Whalen United States
Frederick T. Greenaway United States
José M. Pérez Spain
Alessio Terenzi Italy
Wukun Liu China
Leo F. Faucette United States
Haralabos Zorbas Germany
Qiong Wu China
Clive Metcalfe
Citations per year, relative to Clive Metcalfe Clive Metcalfe (= 1×) peers Qiong Wu

Countries citing papers authored by Clive Metcalfe

Since Specialization
Citations

This map shows the geographic impact of Clive Metcalfe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clive Metcalfe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clive Metcalfe more than expected).

Fields of papers citing papers by Clive Metcalfe

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clive Metcalfe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clive Metcalfe. The network helps show where Clive Metcalfe may publish in the future.

Co-authorship network of co-authors of Clive Metcalfe

This figure shows the co-authorship network connecting the top 25 collaborators of Clive Metcalfe. A scholar is included among the top collaborators of Clive Metcalfe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Clive Metcalfe. Clive Metcalfe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
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Wheeler, Jun X., Meenu Wadhwa, Robin Thorpe, et al.. (2019). The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies. Journal of Biological Chemistry. 294(51). 19616–19634. 11 indexed citations
3.
Metcalfe, Clive, et al.. (2016). Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation. PLoS ONE. 11(10). e0163006–e0163006. 18 indexed citations
4.
Holbrook, Lisa‐Marie, L.S. Kwong, Clive Metcalfe, et al.. (2016). OX133, a monoclonal antibody recognizing protein-bound N-ethylmaleimide for the identification of reduced disulfide bonds in proteins. mAbs. 8(4). 672–677. 7 indexed citations
5.
Banerji, Suneale, Clive Metcalfe, David C. Briggs, et al.. (2016). Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium. Journal of Biological Chemistry. 291(48). 25004–25018. 28 indexed citations
6.
Barclay, A. Neil, et al.. (2015). CD44 Binding to Hyaluronic Acid Is Redox Regulated by a Labile Disulfide Bond in the Hyaluronic Acid Binding Site. PLoS ONE. 10(9). e0138137–e0138137. 22 indexed citations
7.
Garner, Lee, Jun Yan, Clive Metcalfe, et al.. (2015). Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction. Structure. 23(8). 1426–1436. 55 indexed citations
8.
Casadei, Cecilia M., Andrea Gumiero, Clive Metcalfe, et al.. (2014). Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase. Science. 345(6193). 193–197. 118 indexed citations
9.
Metcalfe, Clive, Peter Cresswell, & A. Neil Barclay. (2012). Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor. Open Biology. 2(1). 110036–110036. 29 indexed citations
10.
Murphy, Emma J., et al.. (2011). Crystal structure of guaiacol and phenol bound to a heme peroxidase. FEBS Journal. 279(9). 1632–1639. 30 indexed citations
11.
Metcalfe, Clive, et al.. (2011). Labile disulfide bonds are common at the leucocyte cell surface. Open Biology. 1(3). 110010–110010. 67 indexed citations
12.
Gumiero, Andrea, Emma J. Murphy, Clive Metcalfe, P.C.E. Moody, & Emma Lloyd Raven. (2010). An analysis of substrate binding interactions in the heme peroxidase enzymes: A structural perspective. Archives of Biochemistry and Biophysics. 500(1). 13–20. 70 indexed citations
13.
Gumiero, Andrea, Clive Metcalfe, Arwen R. Pearson, Emma Lloyd Raven, & P.C.E. Moody. (2010). Nature of the Ferryl Heme in Compounds I and II. Journal of Biological Chemistry. 286(2). 1260–1268. 85 indexed citations
14.
Eaton, Graham, Sharad Mistry, Jaswir Basran, et al.. (2009). Evidence for Heme Oxygenase Activity in a Heme Peroxidase. Biochemistry. 48(22). 4738–4746. 5 indexed citations
15.
Murphy, Emma J., Clive Metcalfe, Jaswir Basran, P.C.E. Moody, & Emma Lloyd Raven. (2008). Engineering the Substrate Specificity and Reactivity of a Heme Protein: Creation of an Ascorbate Binding Site in Cytochrome c Peroxidase. Biochemistry. 47(52). 13933–13941. 50 indexed citations
16.
Metcalfe, Clive, Isabel Macdonald, Emma J. Murphy, et al.. (2007). The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. Journal of Biological Chemistry. 283(10). 6193–6200. 68 indexed citations
17.
Metcalfe, Clive, et al.. (2006). Studies on the interaction of extended terpyridyl and triazine metal complexes with DNA. Journal of Inorganic Biochemistry. 100(8). 1314–1319. 70 indexed citations
18.
Metcalfe, Clive, Harry Adams, Ihtshamul Haq, & Jim A. Thomas. (2003). A ruthenium dipyridophenazine complex that binds preferentially to GC sequences. Chemical Communications. 1152–1153. 50 indexed citations
19.
Metcalfe, Clive & Jim A. Thomas. (2003). Kinetically inert transition metal complexes that reversibly bind to DNA. Chemical Society Reviews. 32(4). 215–215. 678 indexed citations breakdown →
20.
Metcalfe, Clive, Michelle Webb, & Jim A. Thomas. (2002). A facile synthetic route to bimetallic ReI complexes containing two dppz DNA intercalating ligands. Chemical Communications. 2026–2027. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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