Siegfried Labeit

25.9k total citations · 3 hit papers
233 papers, 20.2k citations indexed

About

Siegfried Labeit is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Cell Biology. According to data from OpenAlex, Siegfried Labeit has authored 233 papers receiving a total of 20.2k indexed citations (citations by other indexed papers that have themselves been cited), including 164 papers in Molecular Biology, 154 papers in Cardiology and Cardiovascular Medicine and 56 papers in Cell Biology. Recurrent topics in Siegfried Labeit's work include Cardiomyopathy and Myosin Studies (146 papers), Muscle Physiology and Disorders (105 papers) and Cellular Mechanics and Interactions (39 papers). Siegfried Labeit is often cited by papers focused on Cardiomyopathy and Myosin Studies (146 papers), Muscle Physiology and Disorders (105 papers) and Cellular Mechanics and Interactions (39 papers). Siegfried Labeit collaborates with scholars based in Germany, United States and United Kingdom. Siegfried Labeit's co-authors include Henk Granzier, Bernhard Kolmerer, Henk Granzier, Christian Witt, Carol C. Gregorio, Mathias Gautel, D. Labeit, Yiming Wu, K Trombitás and Hiroyuki Sorimachi and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Siegfried Labeit

233 papers receiving 19.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity

1995 977 citations Siegfried Labeit et al. profile →
Cloning of the T gene required in mesoderm formation in the mouse

1990 723 citations Siegfried Labeit et al. profile →
The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking System

2001 523 citations D. Labeit, Henk Granzier et al. Circulation Research profile →

Peers

Countries citing papers authored by Siegfried Labeit

Since Specialization

Citations

This map shows the geographic impact of Siegfried Labeit's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Siegfried Labeit with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Siegfried Labeit more than expected).

Fields of papers citing papers by Siegfried Labeit

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Siegfried Labeit. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Siegfried Labeit. The network helps show where Siegfried Labeit may publish in the future.

Co-authorship network of co-authors of Siegfried Labeit

This figure shows the co-authorship network connecting the top 25 collaborators of Siegfried Labeit. A scholar is included among the top collaborators of Siegfried Labeit based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Siegfried Labeit. Siegfried Labeit is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Discovery of Titin and Its Role in Heart Function and Disease 2025 ·Circulation Research ·Henk Granzier, Siegfried Labeit	10
2	Small-molecule mediated MuRF1 inhibition protects from doxorubicin-induced cardiac atrophy and contractile dysfunction 2024 ·European Journal of Pharmacology ·(unknown), (unknown), Volker Adams, Anselmo Sigari Moriscot, Siegfried Labeit	3
3	Modulation of Titin and Contraction-Regulating Proteins in a Rat Model of Heart Failure with Preserved Ejection Fraction: Limb vs. Diaphragmatic Muscle 2024 ·International Journal of Molecular Sciences ·(unknown), (unknown), Antje Schauer, Antje Augstein, (unknown), Peggy Barthel, Norman Mangner, Siegfried Labeit, T. Scott Bowen, Axel Linke, Volker Adams	2
4	Class I and II Histone Deacetylase Inhibitors as Therapeutic Modulators of Dilated Cardiac Tissue-Derived Mesenchymal Stem/Stromal Cells 2024 ·International Journal of Molecular Sciences ·(unknown), Siegfried Labeit, Daiva Bironaitė	3
5	Small-Molecule Inhibition of MuRF1 Prevents Early Disuse-Induced Diaphragmatic Dysfunction and Atrophy 2023 ·International Journal of Molecular Sciences ·(unknown), (unknown), Luiz Roberto Grassmann Bechara, Julio Cesar Batista Ferreira, Siegfried Labeit, Anselmo Sigari Moriscot	11
6	Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis 2023 ·Biomedicines ·(unknown), (unknown), Jennifer R. Fleming, Vasiliki Zouvelou, (unknown), Francesca Andreetta, Elena Rinaldi, Ornella Simoncini, Renato Mantegazza, Julius Bogomolovas, John Tzartos, Siegfried Labeit, Olga Mayans, Socrates J. Tzartos	2
7	Removal of MuRF1 Increases Muscle Mass in Nemaline Myopathy Models, but Does Not Provide Functional Benefits 2022 ·International Journal of Molecular Sciences ·Johan Lindqvist, Justin Kolb, (unknown), Paola Tonino, (unknown), Siegfried Labeit, Coen A. C. Ottenheijm, Henk Granzier	4
8	miR-29c Increases Protein Synthesis in Skeletal Muscle Independently of AKT/mTOR 2022 ·International Journal of Molecular Sciences ·(unknown), (unknown), (unknown), Siegfried Labeit, Anselmo Sigari Moriscot	5
9	The Effect of Heat Shock on Myogenic Differentiation of Human Skeletal-Muscle-Derived Mesenchymal Stem/Stromal Cells 2022 ·Cells ·(unknown), Siegfried Labeit, Daiva Bironaitė	1
10	The skeletal muscle circadian clock regulates titin splicing through RBM20 2022 ·eLife ·Lance A. Riley, Xiping Zhang, Collin M. Douglas, (unknown), David W. Hammers, Christopher A. Wolff, (unknown), Hailey Olafson, Ping Du, Siegfried Labeit, Michael J. Previs, Eric T. Wang, Karyn A. Esser	13
11	Genetic Ablation of Ankrd1 Mitigates Cardiac Damage during Experimental Autoimmune Myocarditis in Mice 2022 ·Biomolecules ·(unknown), Egidijus Šimoliūnas, (unknown), (unknown), Siegfried Labeit, Virginija Bukelskienė, Julius Bogomolovas	3
12	Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator 2021 ·The Journal of General Physiology ·Robbert van der Pijl, Marloes van den Berg, (unknown), (unknown), Sylvia J. P. Bogaards, (unknown), Paul R. Langlais, Pleuni E. Hooijman, Siegfried Labeit, Leo Heunks, Henk Granzier, Coen A. C. Ottenheijm	22
13	Cardiomyogenic Differentiation Potential of Human Dilated Myocardium-Derived Mesenchymal Stem/Stromal Cells: The Impact of HDAC Inhibitor SAHA and Biomimetic Matrices 2021 ·International Journal of Molecular Sciences ·(unknown), Rūta Aldonytė, (unknown), (unknown), (unknown), (unknown), (unknown), Ramu̅nas Valiokas, Kęstutis Ručinskas, Vilius Janušauskas, Siegfried Labeit, Daiva Bironaitė	5
14	Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells 2020 ·International Journal of Molecular Sciences ·(unknown), Kęstutis Ručinskas, Vilius Janušauskas, Siegfried Labeit, Daiva Bironaitė	6
15	Dysregulated IER3 Expression is Associated with Enhanced Apoptosis in Titin-Based Dilated Cardiomyopathy 2017 ·International Journal of Molecular Sciences ·Qifeng Zhou, (unknown), (unknown), (unknown), Siegfried Labeit, Meinrad Gawaz, Michael Gramlich	10
16	Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease 2016 ·Proceedings of the National Academy of Sciences ·Muzamil Majid Khan, Danilo Lustrino, Wilian A. Silveira, Franziska Wild, (unknown), (unknown), (unknown), Dan Cox, Markus Reischl, Till Marquardt, Dittmar Labeit, Siegfried Labeit, Évelyne Benoit, Jordi Molgó, Hanns Lochmüller, Veit Witzemann, Ísis do Carmo Kettelhut, Luiz Carlos Carvalho Navegantes, Tullio Pozzan, Rüdiger Rudolf	127
17	Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I 2016 ·Open Biology ·Julius Bogomolovas, Jennifer R. Fleming, Brian Anderson, (unknown), Stephan Lange, Bernd Simon, Muzamil Majid Khan, Rüdiger Rudolf, Barbara Franke, Belinda Bullard, Daniel J. Rigden, Henk Granzier, Siegfried Labeit, Olga Mayans	15
18	Multiple Molecular Interactions Implicate the Connectin/Titin N2A Region as a Modulating Scaffold for p94/Calpain 3 Activity in Skeletal Muscle 2008 ·Journal of Biological Chemistry ·Chikako Hayashi, Yasuko Ono, Naoko Doi, Fujiko Kitamura, (unknown), Reiko Mineki, Takao Arai, Hayao Taguchi, Mitsuaki Yanagida, Stephanie Hirner, D. Labeit, Siegfried Labeit, Hiroyuki Sorimachi	91
19	Evidence that nebulin is a protein‐ruler in muscle thin filaments 1991 ·FEBS Letters ·Siegfried Labeit, Toby J. Gibson, A. Lakey, Kevin Leonard, Massimo Zeviani, Peter J. Knight, John Wardale, John Trinick	165
20	A New Method of DNA Sequencing Using Deoxynucleoside α-Thiotriphosphates 1986 ·DNA ·Siegfried Labeit, Hans Lehrach, Roger S. Goody	16

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact