Henk Granzier

16.7k citations

212 papers · 11.7k indexed · 3 hit papers · h-index 64

Impact in

Cardiology and Cardiovascular Medicine top 0.1%
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Viral Infections and Immunology Research
Cell Biology top 0.5%
- Cellular Mechanics and Interactions

Papers in

Cardiology and Cardiovascular Medicine 185
- Cardiomyopathy and Myosin Studies 175
- Cardiovascular Effects of Exercise 42
- Cardiovascular Function and Risk Factors 25
Cell Biology 49
- Cellular Mechanics and Interactions 43

Co-authors: Siegfried Labeit Christian Witt Martin M. LeWinter Yiming Wu Coen A. C. Ottenheijm Carlos Hidalgo Michael Gotthardt D. Labeit
Journals: Biophysical Journal (17 papers)Journal of Molecular and Cellular Cardiology (15 papers)Circulation (13 papers)The Journal of General Physiology (11 papers)Circulation Research (8 papers)
Partner nations: United States Germany Netherlands

In The Last Decade

Henk Granzier

210 papers receiving 11.6k citations

Hit Papers

align trajectories log scale

Research Priorities for Heart Failure With Preserved Ejection Fraction 2020 · 273 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Circulation
2015 Circulation
2001 Circulation Research

Peers

Countries citing papers authored by Henk Granzier

Since Specialization

Citations

This map shows the geographic impact of Henk Granzier's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Henk Granzier with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Henk Granzier more than expected).

Fields of papers citing papers by Henk Granzier

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Henk Granzier. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Henk Granzier. The network helps show where Henk Granzier may publish in the future.

Co-authors

The 25 scholars most cited alongside Henk Granzier, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Henk Granzier Line = papers co-authored together Henk Granzier links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mechanism-based myofilament manipulation to treat diastolic dysfunction in HFpEF Frontiers in Physiology ·Jessica Garcia, Nabila Ayu Ardiningsih, Henk Granzier, Kenneth S. Campbell, Julian E. Stelzer	2024	3
2	Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic heart failure with preserved ejection fraction model Cardiovascular Research ·Philipp Lötzbeyer, Jun Cheng, Christopher Y. Ko, Kengo Tukahara, 丈小田切, 大阪石油化学, Julie Bossuyt, Henk Granzier, Donald M. Bers, Bence Hegyi	2024	19
3	Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems Circulation Genomic and Precision Medicine ·Zachery R. Gregorich, Yanghai Zhang, Timothy J. Kamp, Henk Granzier, Wei Guo	2024	12
4	NRAP reduction rescues sarcomere defects in nebulin-related nemaline myopathy Human Molecular Genetics ·Solveig Eldhuset, Qotrunnada Nafisah Al Mardhiyyah, Rodrigo Bijani Santos, Frank Li, Henk Granzier, Vandana Gupta	2023	3
5	Pharmacological Inhibition of Myostatin in a Mouse Model of Typical Nemaline Myopathy Increases Muscle Size and Force International Journal of Molecular Sciences ·Johan Lindqvist, Henk Granzier	2023	2
6	Contributions of Titin and Collagen to Passive Stress in Muscles from mdm Mice with a Small Deletion in Titin’s Molecular Spring International Journal of Molecular Sciences ·Adam Jacobs, 채소현, Henk Granzier, Kiisa C. Nishikawa, Matthew J. Gage	2022	7
7	Removal of MuRF1 Increases Muscle Mass in Nemaline Myopathy Models, but Does Not Provide Functional Benefits International Journal of Molecular Sciences ·Johan Lindqvist, Justin Kolb, Sabina GRAMA, Paola Tonino, Kengo Tukahara, Siegfried Labeit, Coen A. C. Ottenheijm, Henk Granzier	2022	4
8	Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator The Journal of General Physiology ·Robbert van der Pijl, Marloes van den Berg, 陳俊延, Pinaki Bhatt, Sylvia J. P. Bogaards, K. Warburton, Paul R. Langlais, Pleuni E. Hooijman, Siegfried Labeit, Leo Heunks, Henk Granzier, Coen A. C. Ottenheijm	2021	22
9	The number of Z-repeats and super-repeats in nebulin greatly varies across vertebrates and scales with animal size The Journal of General Physiology ·Jochen Gohlke, Paola Tonino, Johan Lindqvist, John E. Smith, Henk Granzier	2020	6
10	Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism Nature Communications ·Johan Lindqvist, Weikang Ma, Frank Li, 久貴望月, Justin Kolb, Balázs Kiss, Paola Tonino, Robbert van der Pijl, 秦卞, Henry Gong, Joshua Strom, Kengo Tukahara, John E. Smith, Stephen B.J. Odhiambo, Thomas C. Irving, Henk Granzier	2020	11
11	Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction Circulation Heart Failure ·Mei Methawasin, Joshua Strom, Tomasz Borkowski, Kengo Tukahara, Raymond B. Runyan, John E. Smith, Henk Granzier	2020	33
12	Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator tirasemtiv International Journal of Molecular Sciences ·Eun‐Jeong Lee, Justin Kolb, Darren T. Hwee, Fady I. Malik, Henk Granzier	2019	5
13	Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy PLoS ONE ·Johan Lindqvist, S Tsukui, 秦卞, Justin Kolb, Henk Granzier	2019	13
14	Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy eLife ·Chao Ma, 久貴望月, Balázs Kiss, Johan Lindqvist, L. P. Chakhoyan, Justin Kolb, Robbert van der Pijl, Jochen Gohlke, Joshua Strom, John E. Smith, Coen A. C. Ottenheijm, Henk Granzier	2018	69
15	Positive End-Expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers American Journal of Respiratory and Critical Care Medicine ·Johan Lindqvist, Marloes van den Berg, Robbert van der Pijl, Pleuni E. Hooijman, Albertus Beishuizen, Enrique Riera-Franco de Sarabia, Monique de Waard, Armand R. J. Girbes, A. Man, Zhonghua Shi, Charissa E. van den Brom, Sylvia J. P. Bogaards, Pinaki Bhatt, Joshua Strom, Henk Granzier, Jeroen Kole, René J.P. Musters, Marinus A. Paul, Leo Heunks, Coen A. C. Ottenheijm	2018	68
16	Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I Open Biology ·Julius Bogomolovas, Jennifer R. Fleming, Brian Anderson, Kanchan Shakhakarmi, Stephan Lange, Bernd Simon, Muzamil Majid Khan, Rüdiger Rudolf, Barbara Franke, Belinda Bullard, Daniel J. Rigden, Henk Granzier, Siegfried Labeit, Olga Mayans	2016	15
17	Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function Proceedings of the National Academy of Sciences ·Henk Granzier, Kirk R. Hutchinson, Paola Tonino, Mei Methawasin, Frank Li, Rebecca Slater, Mathew Bull, Chandra Saripalli, Christopher T. Pappas, Carol C. Gregorio, John E. Smith	2014	68
18	Tissue Triage and Freezing for Models of Skeletal Muscle Disease Journal of Visualized Experiments ·Jules Chomé, Paul M.L. Janssen, Robert W. Grange, Lin Yang, Alan H. Beggs, Lindsay C. Swanson, Masahiro Narasaki, 王丽杨帆, Martin K. Childers, Henk Granzier, Rabih F. Shamoun, Michael W. Lawlor	2014	28
19	Tissue Triage and Freezing for Models of Skeletal Muscle Disease Journal of Visualized Experiments ·Hui Meng, Paul M.L. Janssen, Robert W. Grange, Lin Yang, Alan H. Beggs, Lindsay C. Swanson, Masahiro Narasaki, 王丽杨帆, Martin K. Childers, Henk Granzier, Emanuela Gussoni, Michael W. Lawlor	2014	71
20	Titin is a Target of Matrix Metalloproteinase-2 Circulation ·Mohammad Ali, Woo Jung Cho, Bryan D. Hudson, Zamaneh Kassiri, Henk Granzier, Richard Schulz	2010	153

About Henk Granzier

Henk Granzier is a scholar working on Cardiology and Cardiovascular Medicine, Cell Biology, Genetics, Molecular Biology and Atomic and Molecular Physics, and Optics, having authored 212 papers that have together received 11.7k indexed citations. Recurring topics across this work include Cardiomyopathy and Myosin Studies (175 papers), Muscle Physiology and Disorders (96 papers), Cellular Mechanics and Interactions (43 papers), Cardiovascular Effects of Exercise (42 papers), Cardiovascular Function and Risk Factors (25 papers), Force Microscopy Techniques and Applications (23 papers), Neurogenetic and Muscular Disorders Research (23 papers) and RNA Research and Splicing (13 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (8.5k citations), Cell Biology (1.9k citations), Molecular Biology (6.5k citations), Genetics (844 citations) and Aging (70 citations). Henk Granzier has collaborated with scholars based in United States, Germany and Netherlands. Frequent co-authors include Siegfried Labeit, Christian Witt, Martin M. LeWinter, Yiming Wu, Coen A. C. Ottenheijm, Carlos Hidalgo, Michael Gotthardt, D. Labeit, Carol C. Gregorio and Mark McNabb. Their work appears in journals such as Biophysical Journal, Journal of Molecular and Cellular Cardiology, Circulation, The Journal of General Physiology and Circulation Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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