Shinya Yamanaka

111.2k total citations · 34 hit papers
278 papers, 75.4k citations indexed

About

Shinya Yamanaka is a scholar working on Molecular Biology, Physiology and Surgery. According to data from OpenAlex, Shinya Yamanaka has authored 278 papers receiving a total of 75.4k indexed citations (citations by other indexed papers that have themselves been cited), including 229 papers in Molecular Biology, 52 papers in Physiology and 23 papers in Surgery. Recurrent topics in Shinya Yamanaka's work include Pluripotent Stem Cells Research (178 papers), CRISPR and Genetic Engineering (138 papers) and Renal and related cancers (56 papers). Shinya Yamanaka is often cited by papers focused on Pluripotent Stem Cells Research (178 papers), CRISPR and Genetic Engineering (138 papers) and Renal and related cancers (56 papers). Shinya Yamanaka collaborates with scholars based in Japan, United States and United Kingdom. Shinya Yamanaka's co-authors include Kazutoshi Takahashi, Tomoko Ichisaka, Keisuke Okita, Koji Tanabe, Megumi Narita, Mari Ohnuki, Kiichiro Tomoda, Masato Nakagawa, Hyenjong Hong and Takashi Aoi and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Shinya Yamanaka

270 papers receiving 73.8k citations

Hit Papers

Induction of Pluripotent Stem Cells from Mouse Embryonic ... 2003 2026 2010 2018 2006 2007 2007 2003 2007 5.0k 10.0k 15.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    2006 18.5k citations Kazutoshi Takahashi, Shinya Yamanaka profile →
  2. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    2007 14.5k citations Kazutoshi Takahashi, Mari Ohnuki et al. profile →
  3. Generation of germline-competent induced pluripotent stem cells
    2007 3.1k citations Keisuke Okita, Tomoko Ichisaka et al. profile →
  4. The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
    2003 2.4k citations Kazutoshi Takahashi, Shinya Yamanaka et al. profile →
  5. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    2007 2.0k citations Masato Nakagawa, Kazutoshi Takahashi et al. Nature Biotechnology profile →
  6. A more efficient method to generate integration-free human iPS cells
    2011 1.4k citations Keisuke Okita, Masato Nakagawa et al. Nature Methods profile →
  7. Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
    2008 1.4k citations Keisuke Okita, Masato Nakagawa et al. Science profile →
  8. Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
    2009 1.0k citations Kazutoshi Takahashi, Tomoko Ichisaka et al. profile →
  9. Induced pluripotent stem cell technology: a decade of progress
    2016 1.0k citations Haruhisa Inoue, Shinya Yamanaka et al. profile →
  10. Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges
    2020 788 citations Shinya Yamanaka profile →
  11. Nanog Is the Gateway to the Pluripotent Ground State
    2009 785 citations Shinya Yamanaka et al. profile →
  12. Induction of pluripotent stem cells from fibroblast cultures
    2007 782 citations Kazutoshi Takahashi, Keisuke Okita et al. Nature Protocols profile →
  13. Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
    2008 757 citations Takashi Aoi, Kojiro Yae et al. Science profile →
  14. Induction of Pluripotent Stem Cells From Adult Human Fibroblasts by Defined Factors
    2008 674 citations Kazutoshi Takahashi, Mari Ohnuki et al. profile →
  15. Variation in the safety of induced pluripotent stem cell lines
    2009 664 citations Yohei Okada, Takashi Aoi et al. Nature Biotechnology profile →
  16. A decade of transcription factor-mediated reprogramming to pluripotency
    2016 596 citations Kazutoshi Takahashi, Shinya Yamanaka profile →
  17. Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells
    2009 582 citations Yoshinori Yoshida, Kazutoshi Takahashi et al. profile →
  18. Induced Pluripotent Stem Cells: Past, Present, and Future
    2012 550 citations Shinya Yamanaka profile →
  19. Strategies and New Developments in the Generation of Patient-Specific Pluripotent Stem Cells
    2007 541 citations Shinya Yamanaka profile →
  20. An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
    2012 540 citations Keisuke Okita, Akira Watanabe et al. profile →
  21. Nuclear reprogramming to a pluripotent state by three approaches
    2010 536 citations Shinya Yamanaka et al. profile →
  22. A Fresh Look at iPS Cells
    2009 494 citations Shinya Yamanaka profile →
  23. mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells
    2004 494 citations Tomoko Ichisaka, Shinya Yamanaka et al. profile →
  24. A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells
    2014 480 citations Masato Nakagawa, Tomoko Ichisaka et al. profile →
  25. Modeling familial Alzheimer's disease with induced pluripotent stem cells
    2011 476 citations Yohei Okada, Wado Akamatsu et al. profile →
  26. Reactivation of the Paternal X Chromosome in Early Mouse Embryos
    2004 428 citations Shinya Yamanaka et al. Science profile →
  27. Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
    2011 418 citations Satoshi Nori, Yohei Okada et al. profile →
  28. Elite and stochastic models for induced pluripotent stem cell generation
    2009 362 citations Shinya Yamanaka profile →
  29. Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells
    2008 345 citations Keisuke Okita, Shinya Yamanaka et al. Circulation profile →
  30. Generation of retinal cells from mouse and human induced pluripotent stem cells
    2009 322 citations Kazutoshi Takahashi, Keisuke Okita et al. profile →
  31. Promotion of direct reprogramming by transformation-deficient Myc
    2010 299 citations Masato Nakagawa, Megumi Narita et al. profile →
  32. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
    2011 294 citations Tomoko Ichisaka, Shinya Yamanaka et al. profile →
  33. Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
    2009 286 citations Shinya Yamanaka et al. profile →
  34. Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
    2012 246 citations Takashi Aoi, Keisuke Okita et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Shinya Yamanaka Japan 99 61.9k 13.7k 10.5k 7.7k 7.6k 278 75.4k
James A. Thomson United States 87 50.7k 0.8× 10.2k 0.7× 10.0k 1.0× 5.2k 0.7× 4.9k 0.6× 253 60.2k
Kazutoshi Takahashi Japan 52 41.2k 0.7× 9.1k 0.7× 6.9k 0.7× 4.7k 0.6× 4.7k 0.6× 127 49.7k
Austin Smith United Kingdom 101 42.4k 0.7× 5.6k 0.4× 5.4k 0.5× 2.8k 0.4× 2.8k 0.4× 224 50.0k
Peter Carmeliet Belgium 151 53.1k 0.9× 9.4k 0.7× 5.7k 0.5× 7.0k 0.9× 6.4k 0.8× 729 100.0k
Irving L. Weissman United States 182 59.2k 1.0× 11.7k 0.9× 6.0k 0.6× 3.5k 0.5× 9.3k 1.2× 836 131.7k
George Q. Daley United States 103 36.8k 0.6× 4.8k 0.3× 4.0k 0.4× 2.5k 0.3× 4.1k 0.5× 391 50.3k
Hideyuki Okano Japan 122 32.0k 0.5× 5.3k 0.4× 2.4k 0.2× 14.9k 1.9× 4.5k 0.6× 1.2k 60.9k
Joseph C. Wu United States 108 24.6k 0.4× 9.2k 0.7× 7.8k 0.7× 4.2k 0.5× 2.2k 0.3× 671 40.1k
Eric N. Olson United States 199 109.1k 1.8× 13.4k 1.0× 2.3k 0.2× 9.3k 1.2× 10.2k 1.3× 761 135.3k
George D. Yancopoulos United States 161 55.1k 0.9× 7.9k 0.6× 2.0k 0.2× 18.5k 2.4× 12.2k 1.6× 430 103.1k

Countries citing papers authored by Shinya Yamanaka

Since Specialization
Citations

This map shows the geographic impact of Shinya Yamanaka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shinya Yamanaka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shinya Yamanaka more than expected).

Fields of papers citing papers by Shinya Yamanaka

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shinya Yamanaka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shinya Yamanaka. The network helps show where Shinya Yamanaka may publish in the future.

Co-authorship network of co-authors of Shinya Yamanaka

This figure shows the co-authorship network connecting the top 25 collaborators of Shinya Yamanaka. A scholar is included among the top collaborators of Shinya Yamanaka based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shinya Yamanaka. Shinya Yamanaka is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Ohta, Shigeki, Yoichi Imaizumi, Yohei Okada, et al.. (2025). Correction: Generation of Human Melanocytes from Induced Pluripotent Stem Cells. PLoS ONE. 20(11). e0337375–e0337375.
2.
Yamanaka, Shinya, et al.. (2025). Protocol for generating transgene-free naive human induced pluripotent stem cells from somatic cells using modified Sendai viral system. STAR Protocols. 6(2). 103700–103700. 1 indexed citations
3.
4.
Yamanaka, Shinya, Naoki Nishimura, Tomoaki Nakamura, et al.. (2024). Successful thoracoscopic operative approach for refractory pneumothorax in interstitial lung disease under local anaesthesia. SHILAP Revista de lepidopterología. 12(3). e01331–e01331. 1 indexed citations
5.
Takahashi, Kazutoshi, Michiko Nakamura, Chikako Okubo, et al.. (2021). The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency. PLoS Genetics. 17(5). e1009587–e1009587. 15 indexed citations
6.
Nakagawa, Masato, Peter Karagiannis, & Shinya Yamanaka. (2016). When Myc's asleep, embryonic stem cells are dormant. The EMBO Journal. 35(8). 801–802. 2 indexed citations
7.
Okada, Yohei, Shinsuke Shibata, Noriyuki Kishi, et al.. (2014). Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes. Stem Cell Reports. 2(5). 648–661. 97 indexed citations
8.
Andrews, Peter W., Joy Cavagnaro, Robert Deans, et al.. (2014). Harmonizing standards for producing clinical-grade therapies from pluripotent stem cells. Nature Biotechnology. 32(8). 724–726. 44 indexed citations
9.
Karagiannis, Peter & Shinya Yamanaka. (2014). The fate of cell reprogramming. Nature Methods. 11(10). 1006–1008. 21 indexed citations
10.
Funakoshi, Shunsuke, Masaki Nomura, Chikako Okubo, et al.. (2014). Abstract 16184: Single Cell RNA Sequencing Reveals Dynamic and Heterogeneous Changes of Transcriptome During Cardiac Differentiation in vitro. Circulation.
11.
Matsumoto, Yoshihisa, Yohei Hayashi, Christopher R. Schlieve, et al.. (2013). Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet Journal of Rare Diseases. 8(1). 190–190. 89 indexed citations
12.
Kobayashi, Yoshiomi, Yohei Okada, Go Itakura, et al.. (2012). Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity. PLoS ONE. 7(12). e52787–e52787. 227 indexed citations
13.
Terada, Yoshio, Yuto Shimamura, Keisuke Hamada, et al.. (2012). Serum levels of soluble secreted [alpha]-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis. 15th International & 14th European Congress of Endocrinology. 29. 17 indexed citations
14.
Inoue, Haruhisa & Shinya Yamanaka. (2011). The Use of Induced Pluripotent Stem Cells in Drug Development. Clinical Pharmacology & Therapeutics. 89(5). 655–661. 160 indexed citations
15.
Nakahata, Tatsutoshi, Tomonari Awaya, Akira Niwa, et al.. (2010). Derivation of Engraftable Myogenic Precursors from Murine ES/iPS cells and Generation of Disease-specific iPS cells from Patients with Duchenne Muscular dystrophy (DMD) and Other Diseases. Rinsho Shinkeigaku. 50(11). 889–889. 3 indexed citations
16.
Miki, Kenji, Atsuhiro Saito, Shigeru Miyagawa, et al.. (2009). Abstract 2965: Cardiomyocyte Sheets Derived From Induced Pluripotent Stem (iPS) Cells Improve Cardiac Function and Attenuate Cardiac Remodeling in Myocardial Infarction in Mice. Circulation. 120. 2 indexed citations
17.
Aoi, Takashi, Kojiro Yae, Masato Nakagawa, et al.. (2008). Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells. Science. 321(5889). 699–702. 757 indexed citations breakdown →
18.
Takahashi, Kazutoshi, Keisuke Okita, Masato Nakagawa, & Shinya Yamanaka. (2007). Induction of pluripotent stem cells from fibroblast cultures. Nature Protocols. 2(12). 3081–3089. 782 indexed citations breakdown →
19.
Hamazaki, Takashi, Masahiro Oka, Shinya Yamanaka, & Naohiro Terada. (2004). Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation. Journal of Cell Science. 117(23). 5681–5686. 90 indexed citations
20.
Yamanaka, Shinya, Xiaoying Zhang, Katsuyuki Miura, Shokei Kim, & Hiroshi Iwao. (1998). The Human Gene Encoding the Lectin-Type Oxidized LDL Receptor (OLR1) Is a Novel Member of the Natural Killer Gene Complex with a Unique Expression Profile. Genomics. 54(2). 191–199. 65 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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