Shigeo Matsuda

4.7k citations

41 papers · 2.9k indexed · 1 hit paper · h-index 26

Co-authors: Floyd E. Romesberg Martin A. Maier Muthiah Manoharan Kallanthottathil G. Rajeev Aaron M. Leconte Akin Akinc Steven M. Ansell Ismail M. Hafez
Topics: DNA and Nucleic Acid Chemistry (31 papers)Advanced biosensing and bioanalysis techniques (29 papers)RNA Interference and Gene Delivery (14 papers)
Cited by: Molecular Biology Cancer Research Organic Chemistry
Journals: Journal of the American Chemical Society Nucleic Acids Research Angewandte Chemie International Edition
Partner nations: United States Japan Canada

In The Last Decade

Shigeo Matsuda

41 papers receiving 2.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**

2012 973 citations Muthusamy Jayaraman, Steven M. Ansell et al. Angewandte Chemie International Edition profile →

Peers

Countries citing papers authored by Shigeo Matsuda

Since Specialization

Citations

This map shows the geographic impact of Shigeo Matsuda's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shigeo Matsuda with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shigeo Matsuda more than expected).

Fields of papers citing papers by Shigeo Matsuda

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shigeo Matsuda. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shigeo Matsuda. The network helps show where Shigeo Matsuda may publish in the future.

Co-authorship network of co-authors of Shigeo Matsuda

This figure shows the co-authorship network connecting the top 25 collaborators of Shigeo Matsuda. A scholar is included among the top collaborators of Shigeo Matsuda based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shigeo Matsuda. Shigeo Matsuda is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Role of a “Magic” Methyl: 2′-Deoxy-2′-α-F-2′-β-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5′-Phosphate Mimics and Mitigation of Off-Target Effects 2022 ·Journal of the American Chemical Society ·Dale C. Guenther,S. Mori,Shigeo Matsuda,Jason A. Gilbert,Jennifer L. S. Willoughby,(unknown),Anna Bisbe,Yongfeng Jiang,Saket Agarwal,(unknown),Maja M. Janas,Klaus Charissé,Martin A. Maier,Martin Egli,Muthiah Manoharan	21
2	RNAs Containing Carbocyclic Ribonucleotides 2021 ·Organic Letters ·(unknown),(unknown),Joel M. Harp,Mark K. Schlegel,Shigeo Matsuda,Martin Egli,Muthiah Manoharan	6
3	siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs 2021 ·Nucleic Acids Research ·(unknown),(unknown),Pawan Kumar,(unknown),Jason A. Gilbert,June Qin,(unknown),(unknown),Yongfeng Jiang,Maja M. Janas,Derek K. O’Flaherty,Ivan Zlatev,Mark K. Schlegel,Shigeo Matsuda,Martin Egli,Muthiah Manoharan	15
4	Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs 2021 ·Nucleic Acids Research ·Mark K. Schlegel,Shigeo Matsuda,Christopher R. Brown,Joel M. Harp,Joseph D. Barry,(unknown),Adam Castoreno,Sally Schofield,(unknown),Muthiah Manoharan,Klaus Charissé,Martin Egli,Martin A. Maier	19
5	Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo 2021 ·Nucleic Acids Research ·(unknown),Nate Taneja,Jennifer L. S. Willoughby,(unknown),Christopher R. Brown,Tuyen Nguyen,Anna Bisbe,Shigeo Matsuda,(unknown),Rajar M. Manoharan,Kallanthottathil G. Rajeev,Martin A. Maier,Ivan Zlatev,Klaus Charissé,Martin Egli,Muthiah Manoharan	55
6	Synthesis, chirality-dependent conformational and biological properties of siRNAs containing 5′-(R)- and 5′-(S)-C-methyl-guanosine 2020 ·Nucleic Acids Research ·Atsushi Mikami,(unknown),Shigeo Matsuda,Alexander V. Kel’in,(unknown),(unknown),Pradeep S. Pallan,Mark K. Schlegel,Ivan Zlatev,Martin Egli,Muthiah Manoharan	19
7	Synthesis and Biophysical Characterization of RNAs Containing 2′-Fluorinated Northern Methanocarbacyclic Nucleotides 2019 ·Organic Letters ·(unknown),Pawan Kumar,(unknown),(unknown),Shigeo Matsuda,Martin Egli,Muthiah Manoharan	12
8	Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity 2018 ·Nucleic Acids Research ·Joel M. Harp,Dale C. Guenther,Anna Bisbe,Lydia A. Perkins,Shigeo Matsuda,Gopal R. Bommineni,Ivan Zlatev,Donald J. Foster,Nate Taneja,Klaus Charissé,Martin A. Maier,Kallanthottathil G. Rajeev,Muthiah Manoharan,Martin Egli	37
9	Reversal of siRNA-mediated gene silencing in vivo 2018 ·Nature Biotechnology ·Ivan Zlatev,Adam Castoreno,Christopher R. Brown,June Qin,(unknown),Mark K. Schlegel,(unknown),Svetlana Shulga‐Morskaya,Huilei Xu,Swati Gupta,Shigeo Matsuda,Akin Akinc,Kallanthottathil G. Rajeev,Muthiah Manoharan,Martin A. Maier,Vasant Jadhav	69
10	Batch ion-exchange membrane electrodialysis of mother liquid discharged from a salt-manufacturing process. Experiment and simulation 2015 ·Separation and Purification Technology ·Yoshinobu Tanaka,(unknown),Shigeo Matsuda,Yoshihiro Sato	11
11	Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo*breakdown → 2012 ·Angewandte Chemie International Edition* ·Muthusamy Jayaraman,Steven M. Ansell,Barbara L. Mui,Ying K. Tam,Jianxin Chen,Xinyao Du,David Butler,(unknown),Shigeo Matsuda,(unknown),Kallanthottathil G. Rajeev,Ismail M. Hafez,Akin Akinc,Martin A. Maier,Mark A. Tracy,Pieter R. Cullis,Thomas D. Madden,Muthiah Manoharan,Michael J. Hope	973
12	Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo** 2012 ·Angewandte Chemie ·Muthusamy Jayaraman,Steven M. Ansell,Barbara L. Mui,Ying K. Tam,Jianxin Chen,Xinyao Du,David Butler,(unknown),Shigeo Matsuda,(unknown),Kallanthottathil G. Rajeev,Ismail M. Hafez,Akin Akinc,Martin A. Maier,Mark A. Tracy,Pieter R. Cullis,Thomas D. Madden,Muthiah Manoharan,Michael J. Hope	122
13	Reversible photopadlocking on double-stranded DNA 2007 ·Chemical Communications ·Kenzo Fujimoto,Shigeo Matsuda,Yoshinaga Yoshimura,(unknown),Isao Saito	11
14	Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs 2007 ·Journal of the American Chemical Society ·Shigeo Matsuda,(unknown),Allison A. Henry,Priyamvada Rai,Steven J. Wilkens,Tammy J. Dwyer,Bernhard H. Geierstanger,David E. Wemmer,Peter G. Schultz,Glen Spraggon,Floyd E. Romesberg	79
15	Site-specific transition of cytosine to uracil via reversible DNA photoligation 2006 ·Chemical Communications ·Kenzo Fujimoto,Shigeo Matsuda,Yoshinaga Yoshimura,Takashi Matsumura,Masayuki Hayashi,Isao Saito	12
16	Efforts towards Expansion of the Genetic Alphabet: Pyridone and Methyl Pyridone Nucleobases 2006 ·Angewandte Chemie ·Aaron M. Leconte,Shigeo Matsuda,Gil Tae Hwang,Floyd E. Romesberg	13
17	Template-directed reversible photocircularization of DNA via 5-vinyldeoxycytidine 2000 ·Tetrahedron Letters ·Kenzo Fujimoto,Shigeo Matsuda,N Ogawa,Masayuki Hayashi,Isao Saito	24
18	Reversible DNA photocircularization on triple helix: effect of vinyl substituent on base stacking 2000 ·Tetrahedron Letters ·Kenzo Fujimoto,Shigeo Matsuda,Masayuki Hayashi,Isao Saito	17
19	Conjugates of a Dinuclear Zinc(II) Complex and DNA Oligomers as Novel Sequence-Selective Artificial Ribonucleases 1998 ·Angewandte Chemie International Edition ·Shigeo Matsuda,(unknown),Akinori Kuzuya,Morio Yashiro,Makoto Komiyama	67
20	Conjugates of a Dinuclear Zinc(II) Complex and DNA Oligomers as Novel Sequence-Selective Artificial Ribonucleases 1998 ·Angewandte Chemie International Edition ·Shigeo Matsuda,(unknown),Akinori Kuzuya,Morio Yashiro,Makoto Komiyama	1

About Shigeo Matsuda

Shigeo Matsuda is a scholar working on Molecular Biology, Cancer Research and Ecology, having authored 41 papers that have together received 2.9k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (31 papers), Advanced biosensing and bioanalysis techniques (29 papers) and RNA Interference and Gene Delivery (14 papers). The work is most often cited by research in Molecular Biology (2.6k citations), Cancer Research (236 citations) and Organic Chemistry (341 citations). Shigeo Matsuda has collaborated with scholars based in United States, Japan and Canada. Frequent co-authors include Floyd E. Romesberg, Martin A. Maier, Muthiah Manoharan, Kallanthottathil G. Rajeev, Aaron M. Leconte, Akin Akinc, Steven M. Ansell, Ismail M. Hafez, Muthusamy Jayaraman and Ying K. Tam. Their work appears in journals such as Journal of the American Chemical Society, Nucleic Acids Research and Angewandte Chemie International Edition.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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