Glen Spraggon

7.2k citations

70 papers · 4.0k indexed · h-index 37

Impact in

Molecular Biology top 5%
- RNA and protein synthesis mechanisms
- Protein Structure and Dynamics
- Chemical Synthesis and Analysis
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
Hematology top 5%

Papers in

Molecular Biology 47
- Protein Structure and Dynamics 11
- RNA and protein synthesis mechanisms 9
- Biochemical and Molecular Research 7
- Glycosylation and Glycoproteins Research 4
Cancer Research 9
- Protease and Inhibitor Mechanisms 8

Co-authors: Stephen J. Everse Russell F. Doolittle Peter G. Schultz Scott A. Lesley Andreas Kreusch S. Atwell Eric Meggers Jennifer L. Harris
Journals: Biochemistry (6 papers)Proceedings of the National Academy of Sciences (6 papers)Structure (6 papers)Journal of the American Chemical Society (5 papers)Biochemical Journal (4 papers)
Partner nations: United States United Kingdom Italy

In The Last Decade

Glen Spraggon

68 papers receiving 3.9k citations

Peers

Countries citing papers authored by Glen Spraggon

Since Specialization

Citations

This map shows the geographic impact of Glen Spraggon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Glen Spraggon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Glen Spraggon more than expected).

Fields of papers citing papers by Glen Spraggon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Glen Spraggon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Glen Spraggon. The network helps show where Glen Spraggon may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Glen Spraggon, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Glen Spraggon Line = papers co-authored together Glen Spraggon links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cryo-EM structures of Nipah virus polymerases and high-throughput RdRp assay development enable anti-NiV drug discovery Nature Communications ·Zhenhang Chen, Jaquelin P. Dudley, Takuya Kageyama, Cosmo Z. Buffalo, Yimam Zenebu, Dongdong Cao, James Hunt, 王利珍, Debapriya Sengupta, Lan Wen, Tiffany Tsang, Lili Xie, Michael DiDonato, Glen Spraggon, Matthew C. Clifton, M. Yomoda, Judith Straimer, Bo Liang	2025	0
2	Discovery of small molecules that target a tertiary-structured RNA Proceedings of the National Academy of Sciences ·重美田本, Bianca J. Lam, Yu Wang, M Skrobisch, Jennifer Shaffer, Katrina F. Tjhung, Badry Bursulaya, Squalen Buletin, Todd Vo, 雄大永松, R. A. Keller, David H. Jones, Glen Spraggon, Pierre‐Yves Michellys, 석재은, Gerald F. Joyce, Jeff Rogers	2022	23
3	Development of a virtual reality platform for effective communication of structural data in drug discovery Journal of Molecular Graphics and Modelling ·Laura J. Kingsley, Vincent Brunet, G. Lelais, Luis de Nicolás y Martínez, 律志佃, 藤野裕美, Stephen R. Fuhs, Kai Wang, Riemann, Glen Spraggon	2019	51
4	Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody PLoS ONE ·Martina Maritan, Daniele Veggi, Roberta Cozzi, Kenneth W. Kinosian, Erika Bartolini, Paola Lo Surdo, Giulietta Maruggi, Glen Spraggon, Matthew J. Bottomley, E. Malito	2018	7
5	Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824 Structure ·Susan E. Cellitti, Jennifer Shaffer, David H. Jones, Tathagata Mukherjee, Meera Gurumurthy, Badry Bursulaya, Helena I. Boshoff, Inhee Choi, Amit Nayyar, Yong Sok Lee, Joseph Cherian, Pornwaratt Niyomrattanakit, Thomas Dick, Ujjini H. Manjunatha, Clifton E. Barry, Glen Spraggon, Bernhard H. Geierstanger	2012	80
6	Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations Protein Science ·Glen Spraggon, Michael Hornsby, Aaron Shipway, David C. Tully, Badry Bursulaya, Henry Danahay, Jennifer L. Harris, Scott A. Lesley	2009	36
7	In vivo Incorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy Journal of the American Chemical Society ·Susan E. Cellitti, David H. Jones, Leanna Lagpacan, Xueshi Hao, Qiong Zhang, Huiyong Hu, Scott M. Brittain, Achim Brinker, Jeremy S. Caldwell, Badry Bursulaya, Glen Spraggon, Ansgar Brock, Youngha Ryu, Tetsuo Uno, Peter G. Schultz, Bernhard H. Geierstanger	2008	158
8	Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design Bioorganic & Medicinal Chemistry Letters ·David C. Tully, Thanakan Kitnithiprapha, Arnab K. Chatterjee, Jennifer Williams, Michael J. Roberts, H. Michael Petrassi, Glen Spraggon, Badry Bursulaya, S. Comes, Aaron Shipway, Andrew M. Schumacher, Henry Danahay, Jennifer L. Harris	2008	15
9	Crystal Structure of Human Pus10, A Novel Pseudouridine Synthase Journal of Molecular Biology ·S. Abyazi, Michael Hornsby, Glen Spraggon, Andreas Kreusch	2007	75
10	Evolution of Vertebrate Fibrin Formation and the Process of its Dissolution Novartis Foundation symposium ·Russell F. Doolittle, Glen Spraggon, Stephen J. Everse	2007	6
11	Integration of Inositol Phosphate Signaling Pathways via Human ITPK1 Journal of Biological Chemistry ·Philip P. Chamberlain, Xun Qian, Amanda R. Stiles, Jaiesoon Cho, David H. Jones, Scott A. Lesley, Elizabeth A. Grabau, Stephen B. Shears, Glen Spraggon	2007	38
12	A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase Molecular Cell ·Francis Kinderman, Choel Kim, Sventja von Daake, Yuliang Ma, Renfeng Yu, Glen Spraggon, Nguyen‐Huu Xuong, Patricia A. Jennings, Susan S. Taylor	2006	165
13	A General Strategy for Creating “Inactive-Conformation” Abl Inhibitors Chemistry & Biology ·Okram Barun, A. S. Nagle, Francisco Adrián, Christian Lee, Pingda Ren, Xia Wang, Taebo Sim, Yongping Xie, Xing Wang, Gang Xia, Glen Spraggon, Markus Warmuth, Yi Liu, Nathanael S. Gray	2006	124
14	Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae Structure ·Christian C. Lee, Xiaofeng Zhu, Kenneth Ng, Carsten Andersen, Yi Liu, Peter Luginbühl, Glen Spraggon, Fumiaki Katagiri	2004	37
15	On the use of DXMS to produce more crystallizable proteins: Structures of the T. maritima proteins TM0160 and TM1171 Protein Science ·Glen Spraggon, Dennis Pantazatos, Heath E. Klock, Ian A. Wilson, Virgil L. Woods, Scott A. Lesley	2004	44
16	Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against theThermotoga maritimaproteome Acta Crystallographica Section D Biological Crystallography ·Rebecca Page, Slawomir K. Grzechnik, Jaume M. Cánaves, Glen Spraggon, Andreas Kreusch, Peter Kühn, Raymond C. Stevens, Scott A. Lesley	2003	74
17	The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum FEBS Letters ·Choel Kim, N.-H. Xuong, Steven L. Edwards, M. D. Madhusudan, Naoaki Sahako, Glen Spraggon, Stanley E. Mills	2002	25
18	The crystal structure of the catalytic domain of human urokinase-type plasminogen activator Structure ·Glen Spraggon, Christopher Phillips, Lene Fogt Lundbo, Chris P. Ponting, Derek Saunders, Daan B. Beetsma, David I. Stuart, E. Yvonne Jones	1995	124
19	Crystallization and X-ray Diffraction Study of Recombinant Platelet-derived Endothelial Cell Growth Factor Journal of Molecular Biology ·Glen Spraggon, David I. Stuart, Chris P. Ponting, Gavin Weightman, Darrell Sleep, E. Yvonne Jones	1993	6
20	Human platelet‐derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase Protein Science ·Geoffrey J. Barton, Chris P. Ponting, Glen Spraggon, Gavin Weightman, Darrell Sleep	1992	43

About Glen Spraggon

Glen Spraggon is a scholar working on Molecular Biology, Cancer Research, Biotechnology, Infectious Diseases and Biophysics, having authored 70 papers that have together received 4.0k indexed citations. Recurring topics across this work include Enzyme Structure and Function (14 papers), Protein Structure and Dynamics (11 papers), Blood properties and coagulation (10 papers), RNA and protein synthesis mechanisms (9 papers), Protease and Inhibitor Mechanisms (8 papers), Biochemical and Molecular Research (7 papers), Glycosylation and Glycoproteins Research (4 papers) and Mass Spectrometry Techniques and Applications (4 papers). The work is most often cited by research in Molecular Biology (2.3k citations), Hematology (339 citations), Cancer Research (327 citations), Endocrinology (107 citations) and Pulmonary and Respiratory Medicine (674 citations). Glen Spraggon has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Stephen J. Everse, Russell F. Doolittle, Peter G. Schultz, Scott A. Lesley, Andreas Kreusch, S. Atwell, Eric Meggers, Jennifer L. Harris, Michael Hornsby and Choel Kim. Their work appears in journals such as Biochemistry, Proceedings of the National Academy of Sciences, Structure, Journal of the American Chemical Society and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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