Seung‐Jae Lee

17.4k total citations · 6 hit papers
132 papers, 13.8k citations indexed

About

Seung‐Jae Lee is a scholar working on Neurology, Physiology and Molecular Biology. According to data from OpenAlex, Seung‐Jae Lee has authored 132 papers receiving a total of 13.8k indexed citations (citations by other indexed papers that have themselves been cited), including 80 papers in Neurology, 54 papers in Physiology and 35 papers in Molecular Biology. Recurrent topics in Seung‐Jae Lee's work include Parkinson's Disease Mechanisms and Treatments (80 papers), Alzheimer's disease research and treatments (36 papers) and Neurological disorders and treatments (22 papers). Seung‐Jae Lee is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (80 papers), Alzheimer's disease research and treatments (36 papers) and Neurological disorders and treatments (22 papers). Seung‐Jae Lee collaborates with scholars based in South Korea, United States and Ethiopia. Seung‐Jae Lee's co-authors include He-Jin Lee, Eun-Jin Bae, Eliezer Masliah, Peter T. Lansbury, Tomas T. Ding, Jean‐Christophe Rochet, Smita S. Patel, Changyoun Kim, Paula Desplats and Kelly A. Conway and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Seung‐Jae Lee

128 papers receiving 13.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

2000 1.3k citations Seung‐Jae Lee et al. Proceedings of the National Academy of Sciences profile →
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

2009 1.2k citations Paula Desplats, He-Jin Lee et al. Proceedings of the National Academy of Sciences profile →
Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

2010 680 citations He-Jin Lee, Christina Patrick et al. Journal of Biological Chemistry profile →
Intravesicular Localization and Exocytosis of α-Synuclein and its Aggregates

2005 653 citations He-Jin Lee, Seung‐Jae Lee et al. profile →
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

2013 650 citations Changyoun Kim, Dong Hwan Ho et al. profile →
Vesicle Permeabilization by Protofibrillar α-Synuclein: Implications for the Pathogenesis and Treatment of Parkinson's Disease

2001 581 citations Seung‐Jae Lee et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Seung‐Jae Lee South Korea	53	8.7k	5.6k	4.3k	4.0k	3.3k	132	13.8k
Robert L. Nussbaum United States	39	9.6k 1.1×	4.2k 0.8×	4.4k 1.0×	5.2k 1.3×	2.3k 0.7×	54	14.1k
Michael G. Schlossmacher United States	47	6.9k 0.8×	5.0k 0.9×	3.7k 0.9×	3.3k 0.8×	1.8k 0.5×	81	11.6k
Benoit I. Giasson United States	78	14.0k 1.6×	8.8k 1.6×	5.5k 1.3×	6.8k 1.7×	4.5k 1.4×	206	20.6k
Michael K. Lee United States	61	8.0k 0.9×	7.6k 1.4×	8.0k 1.9×	5.6k 1.4×	3.2k 1.0×	155	20.0k
Andrew B. West United States	55	6.9k 0.8×	2.6k 0.5×	5.0k 1.2×	2.9k 0.7×	2.3k 0.7×	129	11.9k
Mel Β. Feany United States	54	5.2k 0.6×	4.8k 0.9×	5.4k 1.3×	4.8k 1.2×	1.8k 0.5×	106	13.4k
Poul Henning Jensen Denmark	52	5.7k 0.7×	3.2k 0.6×	2.8k 0.7×	2.6k 0.6×	1.5k 0.5×	191	9.8k
Leonidas Stefanis Greece	55	7.4k 0.9×	3.6k 0.6×	4.8k 1.1×	3.6k 0.9×	1.8k 0.5×	277	13.4k
Luc Bousset France	48	5.3k 0.6×	3.7k 0.7×	3.6k 0.9×	2.4k 0.6×	2.3k 0.7×	109	9.3k
Veerle Baekelandt Belgium	58	4.7k 0.5×	2.7k 0.5×	5.3k 1.2×	3.4k 0.8×	1.8k 0.5×	218	11.7k

Countries citing papers authored by Seung‐Jae Lee

Since Specialization

Citations

This map shows the geographic impact of Seung‐Jae Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seung‐Jae Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seung‐Jae Lee more than expected).

Fields of papers citing papers by Seung‐Jae Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seung‐Jae Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seung‐Jae Lee. The network helps show where Seung‐Jae Lee may publish in the future.

Co-authorship network of co-authors of Seung‐Jae Lee

This figure shows the co-authorship network connecting the top 25 collaborators of Seung‐Jae Lee. A scholar is included among the top collaborators of Seung‐Jae Lee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Seung‐Jae Lee. Seung‐Jae Lee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Kim, Jae‐Seok, et al.. (2025). A 3D-Printed Aqueous Drainage Tube with an Expandable Inner Diameter to Accommodate the Intraocular Pressure (IOP) Fluctuations After Glaucoma Surgery. Polymers. 17(1). 118–118.

Lee, Seung‐Jae & Woojoo Lee. (2025). A Review of Mendelian Randomization: Assumptions, Methods, and Application to Obesity-Related Diseases. Journal of Obesity & Metabolic Syndrome. 34(1). 14–26. 2 indexed citations

Lee, Seung‐Jae, Hee‐Seung Lee, Joonho Park, et al.. (2025). Lead‐Free Tin‐Based Perovskite LEDs Toward Rec. 2020: Organic Anion Coordination for Oxidation Suppression. Advanced Science. 13(2). e11006–e11006.

Ahn, Jeeyun, et al.. (2023). Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils. Acta Neuropathologica Communications. 11(1). 83–83. 8 indexed citations

Strohäker, Timo, Lars Tatenhorst, Lucas Caldi Gomes, et al.. (2023). Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain. Brain Pathology. 33(5). e13196–e13196. 8 indexed citations

Frieg, Benedikt, Timo Strohäker, Christian Dienemann, et al.. (2022). Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology. 5(1). 1040–1040. 16 indexed citations

Bae, Eun-Jin, Min-Sun Choi, Jeong Tae Kim, et al.. (2022). TNF-α promotes α-synuclein propagation through stimulation of senescence-associated lysosomal exocytosis. Experimental & Molecular Medicine. 54(6). 788–800. 56 indexed citations

You, Jueng Soo, et al.. (2022). Senescence and impaired DNA damage responses in alpha-synucleinopathy models. Experimental & Molecular Medicine. 54(2). 115–128. 43 indexed citations

Yoo, Dallah, Won‐Jae Lee, Seung‐Jae Lee, et al.. (2021). A Novel TFG Mutation in a Korean Family with α‐Synucleinopathy and Amyotrophic Lateral Sclerosis. Movement Disorders. 37(2). 384–391. 8 indexed citations

10.

Jo, Junghyun, Weonjin Yu, Alfred Xuyang Sun, et al.. (2021). Lewy Body–like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α‐Synuclein Mutations. Annals of Neurology. 90(3). 490–505. 58 indexed citations

11.

Wulansari, Noviana, Mi‐Yoon Chang, Eun-Jin Bae, et al.. (2021). Neurodevelopmental defects and neurodegenerative phenotypes in human brain organoids carrying Parkinson’s disease-linked DNAJC6 mutations. Science Advances. 7(8). 94 indexed citations

12.

Bae, Eun-Jin, Dong Hwan Ho, Jin Woo Jung, et al.. (2012). Lipid Peroxidation Product 4-Hydroxy-2-Nonenal Promotes Seeding-Capable Oligomer Formation and Cell-to-Cell Transfer of α-Synuclein. Antioxidants and Redox Signaling. 18(7). 770–783. 98 indexed citations

13.

Lee, Seung‐Jae, Yon-Suk Kim, Seong-Eun Kim, et al.. (2012). Purification and Characterization of a Novel Angiotensin I-Converting Enzyme Inhibitory Peptide Derived from an Enzymatic Hydrolysate of Duck Skin Byproducts. Journal of Agricultural and Food Chemistry. 60(40). 10035–10040. 23 indexed citations

14.

Kim, Kwang S., Yu Ree Choi, Ji Young Park, et al.. (2012). Proteolytic Cleavage of Extracellular α-Synuclein by Plasmin. Journal of Biological Chemistry. 287(30). 24862–24872. 62 indexed citations

15.

Lee, He-Jin, et al.. (2011). Enzyme-linked immunosorbent assays for alpha-synuclein with species and multimeric state specificities. Journal of Neuroscience Methods. 199(2). 249–257. 23 indexed citations

16.

Lee, Seung‐Jae, Ji Hoon Phi, D. G. Kim, et al.. (2011). Prognostic classification of pediatric medulloblastoma based on chromosome 17p loss, expression of MYCC and MYCN, and Wnt pathway activation. Neuro-Oncology. 14(2). 203–214. 34 indexed citations

17.

Jung, Jin‐Woo, et al.. (2010). Non‐classical exocytosis of α‐synuclein is sensitive to folding states and promoted under stress conditions. Journal of Neurochemistry. 113(5). 1263–1274. 235 indexed citations

18.

Desplats, Paula, He-Jin Lee, Eun-Jin Bae, et al.. (2009). Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein. Proceedings of the National Academy of Sciences. 106(31). 13010–13015. 1156 indexed citations breakdown →

19.

Shin, Soon Young, Haengseok Song, Chang Gun Kim, et al.. (2009). Egr-1 Is Necessary for Fibroblast Growth Factor-2-induced Transcriptional Activation of the Glial Cell Line-derived Neurotrophic Factor in Murine Astrocytes. Journal of Biological Chemistry. 284(44). 30583–30593. 23 indexed citations

20.

Kim, Eun‐Kyung, et al.. (2009). Protective Effects Against H ₂ O ₂ -Induced Damage by Enzymatic Hydrolysates of an Edible Brown Seaweed, Sea Tangle ( Laminaria japonica ). Journal of Medicinal Food. 12(1). 159–166. 25 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact