Seth L. Alper

23.5k citations

323 papers · 16.3k indexed · 2 hit papers · h-index 71

Impact in

Nephrology top 0.2%
- Renal Diseases and Glomerulopathies
Molecular Biology top 0.5%
- Ion Transport and Channel Regulation
- Ion channel regulation and function

Papers in

Nephrology 38
- Renal Diseases and Glomerulopathies 16
Sensory Systems 22

Co-authors: Carlo Brugnara Alan K. Stuart-Tilley Marina N. Chernova Boris E. Shmukler Dennis Brown Harvey F. Lodish Lucia De Franceschi Alok K. Sharma
Journals: American Journal of Physiology-Cell Physiology (40 papers)Journal of Biological Chemistry (26 papers)Proceedings of the National Academy of Sciences (12 papers)Journal of Clinical Investigation (11 papers)American Journal of Physiology-Renal Physiology (11 papers)
Partner nations: United States Germany France

In The Last Decade

Seth L. Alper

319 papers receiving 16.0k citations

Hit Papers

align trajectories log scale

Glymphatic System Impairment in Alzheimer’s Disease and Idiopathic Normal Pressure Hydrocephalus 2020 · 266 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Trends in Molecular Medicine
2001 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Seth L. Alper

Since Specialization

Citations

This map shows the geographic impact of Seth L. Alper's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seth L. Alper with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seth L. Alper more than expected).

Fields of papers citing papers by Seth L. Alper

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seth L. Alper. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seth L. Alper. The network helps show where Seth L. Alper may publish in the future.

Co-authors

The 25 scholars most cited alongside Seth L. Alper, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Seth L. Alper Line = papers co-authored together Seth L. Alper links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel K _Ca 3.1 Proceedings of the National Academy of Sciences ·Seow Theng Ong, Youngwoo Nam, Joshua A. Nasburg, Alena Ramanishka, Xuan Rui Ng, Zhong Zhuang, Stephanie Shee Min Goay, Hai M. Nguyen, Latika Singh, Vikrant Singh, Alicia Rivera, M. Elaine Eyster, Yang Xu, Seth L. Alper, Heike Wulff, Miao Zhang, K. George Chandy	2025	2
2	Role of ecto‐5′‐nucleotidase in bladder function The FASEB Journal ·Sagar Barge, Ali Wu, Lanlan Zhang, Simon C. Robson, Aria F. Olumi, Seth L. Alper, Mark L. Zeidel, Weiqun Yu	2024	2
3	Computational drug repositioning of clopidogrel as a novel therapeutic option for focal segmental glomerulosclerosis Translational research ·Christoph A. Gebeshuber, Lisa Daniel-Fischer, Heinz Regele, Helga Schachner, Christoph Aufricht, Christoph Kornauth, Matthias Ley, Seth L. Alper, Rebecca Herzog, Klaus Kratochwill, Paul Perco	2023	6
4	Hereditary anemia caused by multilocus inheritance of <i>PIEZO1</i>, <i>SLC4A1</i> and <i>ABCB6</i> mutations: a diagnostic and therapeutic challenge Haematologica ·Barbara Eleni Rosato, Seth L. Alper, Giovanna Tomaiuolo, Roberta Russo, Achille Iolascon, Immacolata Andolfo	2022	4
5	Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis Antioxidants ·Enrica Federti, Alessandro Mattè, Veronica Riccardi, Kevin Peikert, Seth L. Alper, Adrian Danek, Ruth H. Walker, Angela Siciliano, Iana Iatcenko, Andreas Hermann, Lucia De Franceschi	2021	8
6	Nobel prize in physiology or medicine 2021, receptors for temperature and touch: Implications for hematology American Journal of Hematology ·Immacolata Andolfo, Seth L. Alper, Achille Iolascon	2021	7
7	Lithium preserves peritoneal membrane integrity by suppressing mesothelial cell αB-crystallin Science Translational Medicine ·Rebecca Herzog, Juan Manuel Sacnun, Guadalupe Tirma Gónzalez-Mateo, Maria Bartosova, Katarzyna Bialas, Anja Wagner, Markus Unterwurzacher, Isabel J. Sobieszek, Lisa Daniel-Fischer, Krisztina Rusai, Lucía Pascual‐Antón, Klaus Kaczirek, Andreas Vychytil, Claus Peter Schmitt, Manuel López‐Cabrera, Seth L. Alper, Christoph Aufricht, Klaus Kratochwill	2021	23
8	Peritoneal Dialysis Fluid Supplementation with Alanyl-Glutamine Attenuates Conventional Dialysis Fluid-Mediated Endothelial Cell Injury by Restoring Perturbed Cytoprotective Responses Biomolecules ·Rebecca Herzog, Maria Bartosova, Silvia Tarantino, Anja Wagner, Markus Unterwurzacher, Juan Manuel Sacnun, Anton Lichtenauer, Lilian Kuster, Betti Schaefer, Seth L. Alper, Christoph Aufricht, Claus Peter Schmitt, Klaus Kratochwill	2020	18
9	Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis Journal of the American Society of Nephrology ·Di Feng, Mukesh Kumar, Jan Muntel, Susan B. Gurley, Gabriel Birrane, Isaac E. Stillman, Lai Ding, Minxian Wang, Saima Ahmed, Johannes Schlöndorff, Seth L. Alper, Tom Ferrante, Susan L. Marquez, Carlos F. Ng, Richard Novák, Donald E. Ingber, Hanno Steen, Martin R. Pollak	2020	22
10	Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus Nature Medicine ·Jason K. Karimy, Jinwei Zhang, David B. Kurland, Brianna C. Theriault, Daniel Durán, Jesse A. Stokum, Charuta G. Furey, Xu Zhou, M. Shahid Mansuri, Julio D. Montejo, Alberto Vera, Michael L. DiLuna, Eric Delpire, Seth L. Alper, Murat Günel, Volodymyr Gerzanich, Ruslan Medzhitov, J. Marc Simard, Kristopher T. Kahle	2017	253
11	Functional and Transcriptomic Characterization of Peritoneal Immune-Modulation by Addition of Alanyl-Glutamine to Dialysis Fluid Scientific Reports ·Rebecca Herzog, Lilian Kuster, Julia Powers Becker, Tobias Gluexam, Dietmar Pils, Andreas Spittler, Manoj Bhasin, Seth L. Alper, Andreas Vychytil, Christoph Aufricht, Klaus Kratochwill	2017	14
12	A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis Blood ·Francesca Lupo, Elena Tibaldi, Alessandro Mattè, Alok K. Sharma, Anna Maria Brunati, Seth L. Alper, Carlo Zancanaro, Donatella Benati, Angela Siciliano, Mariarita Bertoldi, Francesca Zonta, Alexander Storch, Ruth H. Walker, Adrian Danek, Benedikt Bader, Andreas Hermann, Lucia De Franceschi	2016	48
13	Metastatic Infiltrating Ductal Carcinoma of the Breast to the Colon: A Case Report and Literature Review SHILAP Revista de lepidopterología ·Salih Samo, Muhammed Sherid, Husein Husein, Samian Sulaiman, Jeffrey V. Brower, Seth L. Alper, Margaret Yungbluth, John A. Vainder	2013	6
14	Deletion of the Chloride Transporter Slc26a7 Causes Distal Renal Tubular Acidosis and Impairs Gastric Acid Secretion Journal of Biological Chemistry ·Jie Xu, Penghong Song, Suguru Nakamura, Marian L. Miller, Sharon Barone, Seth L. Alper, Brigitte Riederer, Janina Bonhagen, Lois J. Arend, Hassane Amlal, Ursula Seidler, Manoocher Soleimani	2009	81
15	Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach Proceedings of the National Academy of Sciences ·Jie Xu, Penghong Song, Marian L. Miller, Franck Borgèse, Sharon Barone, Brigitte Riederer, Zhaohui Wang, Seth L. Alper, John G. Forte, Gary E. Shull, J. Ehrenfeld, Ursula Seidler, Manoocher Soleimani	2008	88
16	Drought- and salt-tolerant plants result from overexpression of the AVP1 H ⁺ -pump Proceedings of the National Academy of Sciences ·Roberto A. Gaxiola, Jisheng Li, Soledad Undurraga, Lien M. Dang, Gethyn J. Allen, Seth L. Alper, Gerald R. Fink Hit paper breakdown →	2001	565
17	Novel AE1 mutations in recessive distal renal tubular acidosis. Loss-of-function is rescued by glycophorin A. Journal of Clinical Investigation ·V S Tanphaichitr, Achra Sumboonnanonda, Hiroshi Ideguchi, Chairat Shayakul, Carlo Brugnara, Motoshi Takao, Gavivann Veerakul, Seth L. Alper	1998	135
18	The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells. Journal of Clinical Investigation ·Paul A. Rufo, Liang Jiang, S Moe, Carlo Brugnara, Seth L. Alper, Wayne I. Lencer	1996	57
19	Duplication of 10 nucleotides in the erythroid band 3 (AE1) gene in a kindred with hereditary spherocytosis and band 3 protein deficiency (band 3PRAGUE). Journal of Clinical Investigation ·Petr Jarolı́m, Hillard Rubin, S C Liu, Michael Cho, V Brabec, Laura H. Derick, S J Yi, Sara Teresinha Olalla Saad, Seth L. Alper, Carlo Brugnara	1994	82
20	The fodrin-ankyrin cytoskeleton of choroid plexus preferentially colocalizes with apical Na+K(+)-ATPase rather than with basolateral anion exchanger AE2. Journal of Clinical Investigation ·Seth L. Alper, Alan K. Stuart-Tilley, Charles F. Simmons, Dennis Brown, Detlev Drenckhahn	1994	89

About Seth L. Alper

Seth L. Alper is a scholar working on Nephrology, Sensory Systems, Physiology, Molecular Biology and Genetics, having authored 323 papers that have together received 16.3k indexed citations. Recurring topics across this work include Ion channel regulation and function (108 papers), Ion Transport and Channel Regulation (107 papers), Erythrocyte Function and Pathophysiology (85 papers), Neuroscience and Neuropharmacology Research (27 papers), Hemoglobinopathies and Related Disorders (25 papers), Pancreatic function and diabetes (24 papers), Renal Diseases and Glomerulopathies (16 papers) and Neonatal Health and Biochemistry (16 papers). The work is most often cited by research in Nephrology (1.8k citations), Molecular Biology (9.8k citations), Physiology (3.6k citations), Sensory Systems (670 citations) and Genetics (1.4k citations). Seth L. Alper has collaborated with scholars based in United States, Germany and France. Frequent co-authors include Carlo Brugnara, Alan K. Stuart-Tilley, Marina N. Chernova, Boris E. Shmukler, Dennis Brown, Harvey F. Lodish, Lucia De Franceschi, Alok K. Sharma, Lianwei Jiang and Gerald R. Fink. Their work appears in journals such as American Journal of Physiology-Cell Physiology, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and American Journal of Physiology-Renal Physiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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