Seema Gupta

3.7k citations

163 papers · 2.8k · 1 hit paper · h-index 24

Impact in

Oncology top 2%
- Drug Transport and Resistance Mechanisms
Hepatology top 5%
- Liver physiology and pathology

Papers in

Molecular Biology 37
- dental development and anomalies 12
- Cell death mechanisms and regulation 6
Oral Surgery 28
- Dental Radiography and Imaging 19

Co-authors: Phillip B. Hylemon (7 shared papers)Paul Dent (11 shared papers)Elaine Studer (9 shared papers)J P Singh (2 shared papers)Steven Grant (8 shared papers)Paul Dent (1 shared paper)R. Todd Stravitz (1 shared paper)Philip B. Hylemon (7 shared papers)
Journals: Hepatology (8 papers)Journal of Biological Chemistry (3 papers)Cancer Biology & Therapy (3 papers)Planta Medica (3 papers)American Journal of Orthodontics and Dentofacial Orthopedics (2 papers)
Partner nations: India United States United Kingdom

In The Last Decade

Seema Gupta

137 papers receiving 2.7k citations

Hit Papers

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Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis 2014 · 384 citations

Peers

Countries citing papers authored by Seema Gupta

Since Specialization

Citations

This map shows the geographic impact of Seema Gupta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seema Gupta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seema Gupta more than expected).

Fields of papers citing papers by Seema Gupta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seema Gupta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seema Gupta. The network helps show where Seema Gupta may publish in the future.

Co-authors

The 25 scholars most cited alongside Seema Gupta, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Seema Gupta Line = papers co-authored together Seema Gupta links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 163 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis Journal of Translational Medicine ·Alpha A. Fowler, Aamer Syed, Shelley Knowlson, Robin Sculthorpe, Don Farthing, Christine DeWilde, Christine Farthing, Terri Larus, Erika J. Martin, Donald F. Brophy, Seema Gupta, Bernard Fisher, Ramesh Natarajan Hit paper breakdown →	2014	384
2	Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes Is Mediated by the c-Jun N-terminal Kinase Pathway Journal of Biological Chemistry ·Seema Gupta, R. Todd Stravitz, Paul Dent, Phillip B. Hylemon	2001	281
3	Deoxycholic Acid (DCA) Causes Ligand-independent Activation of Epidermal Growth Factor Receptor (EGFR) and FAS Receptor in Primary Hepatocytes: Inhibition of EGFR/Mitogen-activated Protein Kinase-Signaling Module Enhances DCA-induced Apoptosis Molecular Biology of the Cell ·Liang Qiao, Elaine Studer, Kevin Leach, Robert McKinstry, Seema Gupta, Roy H. Decker, Rakesh C. Kukreja, Kristoffer Valerie, Prakash Nagarkatti, Wafik S. El‐Deiry, Jeffery D. Molkentin, Rupert Schmidt‐Ullrich, Paul B. Fisher, Steven Grant, Philip B. Hylemon, Paul Dent	2001	195
4	Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH₂-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes Molecular and Cellular Biology ·Liang Qiao, Song Iy Han, Youwen Fang, Jong Sung Park, Seema Gupta, Donna Gilfor, George P. Amorino, Kristoffer Valerie, Linda Sealy, John F. Engelhardt, Steven Grant, Philip B. Hylemon, Paul Dent	2003	127
5	A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4. Proceedings of the National Academy of Sciences ·Seema Gupta, Tillmann Hassel, J P Singh	1995	124
6	Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes Hepatology ·Liang Qiao, Adly Yacoub, Elaine Studer, Seema Gupta, Xin Pei, Steven Grant, Philip B. Hylemon, Paul Dent	2002	123
7	Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes Hepatology ·Youwen Fang, Song Iy Han, Clint Mitchell, Seema Gupta, Elaine Studer, Steven Grant, Phillip B. Hylemon, Paul Dent	2004	109
8	LXRα is the dominant regulator of CYP7A1 transcription Biochemical and Biophysical Research Communications ·Seema Gupta, William M. Pandak, Phillip B. Hylemon	2002	107
9	Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin–sensitive mechanism in murine and human hepatocytes† Hepatology ·Paul Dent, Youwen Fang, Seema Gupta, Elaine Studer, Clint Mitchell, Sarah Spiegel, Philip B. Hylemon	2005	100
10	Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression. The Journal of Cell Biology ·Seema Gupta, J P Singh	1994	98
11	Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes Hepatology ·Yi-Ping Rao, Elaine Studer, Todd R. Stravitz, Seema Gupta, Liang Qiao, Paul Dent, Phillip B. Hylemon	2002	88
12	mymAoperon ofMycobacterium tuberculosis: its regulation and importance in the cell envelope FEMS Microbiology Letters ·Amit Singh, Shruti Jain, Seema Gupta, Taposh K. Das, Akhilesh K. Tyagi	2003	74
13	Deoxycholic Acid Activates the c-Jun N-terminal Kinase Pathway via FAS Receptor Activation in Primary Hepatocytes Journal of Biological Chemistry ·Seema Gupta, Ramesh Natarajan, Shawn G. Payne, Elaine Studer, Sarah Spiegel, Paul Dent, Phillip B. Hylemon	2004	70
14	Use of natural carotenoids for pigmentation in fishes Seema Gupta, Ashish Kumar Jha, Anugunj Pal, G. Venkateshwarlu	2007	65
15	Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes Hepatology ·Song Iy Han, Elaine Studer, Seema Gupta, Youwen Fang, Liang Qiao, Weiqun Li, Steven Grant, Philip B. Hylemon, Paul Dent	2004	52
16	Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes Hepatology ·Youwen Fang, Song Iy Han, Clint Mitchell, Seema Gupta, Elaine Studer, Steven Grant, Phillip B. Hylemon, Paul Dent	2004	48
17	Phase I-II study of high-dose epirubicin in advanced non-small-cell lung cancer. Journal of Clinical Oncology ·Ronald Feld, Ryszard Wierzbicki, P L Walde, Frances A. Shepherd, William K. Evans, Seema Gupta, P. Shannon, M. Lassus	1992	42
18	Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53 Hepatology ·Liang Qiao, Robert McKinstry, Seema Gupta, Donna Gilfor, Jolene J. Windle, Philip B. Hylemon, Steven Grant, Paul B. Fisher, Paul Dent	2002	40
19	Multiple Cyclin Kinase Inhibitors Promote Bile Acid-induced Apoptosis and Autophagy in Primary Hepatocytes via p53-CD95-dependent Signaling Journal of Biological Chemistry ·Guo Zhang, Margaret A. Park, Clint Mitchell, Teneille Walker, Hossein A. Hamed, Elaine Studer, Martin Graf, Mohamed Rahmani, Seema Gupta, Philip B. Hylemon, Paul B. Fisher, Steven Grant, Paul Dent	2008	37
20	Lipid peroxide levels and antioxidant status in alcoholic liver disease Indian Journal of Clinical Biochemistry ·Seema Gupta, Rajesh Pandey, R Katyal, Hari Krishan Aggarwal, Rakesh Aggarwal, Sameer Aggarwal	2005	34

About Seema Gupta

Seema Gupta is a scholar working on Molecular Biology, Oral Surgery, Surgery, Epidemiology and Orthodontics, having authored 163 papers that have together received 2.8k indexed citations. Recurring topics across this work include Orthodontics and Dentofacial Orthopedics (20 papers), Dental Radiography and Imaging (19 papers), dental development and anomalies (12 papers), Drug Transport and Resistance Mechanisms (11 papers), Temporomandibular Joint Disorders (10 papers), Liver Disease Diagnosis and Treatment (7 papers), Cell death mechanisms and regulation (6 papers) and Study of Mite Species (6 papers). The work is most often cited by research in Oncology (1.0k citations), Hepatology (242 citations), Nutrition and Dietetics (381 citations), Critical Care and Intensive Care Medicine (127 citations) and Complementary and Manual Therapy (53 citations). Seema Gupta has collaborated with scholars based in India, United States and United Kingdom. Frequent co-authors include Phillip B. Hylemon, Paul Dent, Elaine Studer, J P Singh, Steven Grant, Paul Dent, R. Todd Stravitz, Philip B. Hylemon, Liang Qiao and Youwen Fang. Their work appears in journals such as Hepatology, Journal of Biological Chemistry, Cancer Biology & Therapy, Planta Medica and American Journal of Orthodontics and Dentofacial Orthopedics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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