Scott Classen

2.5k citations

20 papers · 2.0k indexed · h-index 16

Impact in

Structural Biology top 5%
Molecular Biology top 5%
- DNA Repair Mechanisms
- DNA and Nucleic Acid Chemistry
- Cancer therapeutics and mechanisms
- CRISPR and Genetic Engineering
- Protein Structure and Dynamics
- Genomics and Chromatin Dynamics

Papers in ⓘ

Molecular Biology 15
- DNA Repair Mechanisms 8
- Protein Structure and Dynamics 5
- Genomics and Chromatin Dynamics 3
- DNA and Nucleic Acid Chemistry 3
- RNA and protein synthesis mechanisms 2
- RNA modifications and cancer 2
- Advanced biosensing and bioanalysis techniques 1
Materials Chemistry 6
- Enzyme Structure and Function 6

Co-authors: John A. Tainer (11 shared papers)James M. Berger (2 shared papers)Stéphane Olland (1 shared paper)Greg L. Hura (5 shared papers)Michal Hammel (5 shared papers)Grant Guenther (3 shared papers)Susan E. Tsutakawa (3 shared papers)James M. Holton (3 shared papers)
Journals: Cell (2 papers)Biochemistry (2 papers)Journal of the American Chemical Society (1 paper)Nature Structural & Molecular Biology (1 paper)FEBS Journal (1 paper)
Partner nations: United States United Kingdom Canada

In The Last Decade

Scott Classen

20 papers receiving 2.0k citations

Peers

Countries citing papers authored by Scott Classen

Since Specialization

Citations

This map shows the geographic impact of Scott Classen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Scott Classen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Scott Classen more than expected).

Fields of papers citing papers by Scott Classen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Scott Classen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Scott Classen. The network helps show where Scott Classen may publish in the future.

Co-authors

The 25 scholars most cited alongside Scott Classen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Scott Classen Line = papers co-authored together Scott Classen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair Cell ·R. Scott Williams, Gerald E. Dodson, Oliver Limbo, Yoshiki Yamada, Jessica S. Williams, Grant Guenther, Scott Classen, J. N. Mark Glover, Hiroshi Iwasaki, Paul Russell, John A. Tainer	2009	254
2	Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily Cell ·Susan E. Tsutakawa, Scott Classen, B.R. Chapados, A.S. Arvai, L. David Finger, Grant Guenther, Christopher G. Tomlinson, Peter Thompson, Altaf H. Sarker, Binghui Shen, Priscilla K. Cooper, Jane A. Grasby, John A. Tainer	2011	239
3	Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 Proceedings of the National Academy of Sciences ·Scott Classen, Stéphane Olland, James M. Berger	2003	218
4	Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source Journal of Applied Crystallography ·Scott Classen, Greg L. Hura, James M. Holton, Robert P. Rambo, Ivan Rodic, Patrick J. McGuire, Kevin Dyer, Michal Hammel, G. Meigs, Kenneth A. Frankel, John A. Tainer	2013	202
5	High-Throughput SAXS for the Characterization of Biomolecules in Solution: A Practical Approach Methods in molecular biology ·Kevin Dyer, Michal Hammel, Robert P. Rambo, Susan E. Tsutakawa, Ivan Rodic, Scott Classen, John A. Tainer, Greg L. Hura	2013	162
6	A Microfluidic Device for Kinetic Optimization of Protein Crystallization and In Situ Structure Determination Journal of the American Chemical Society ·Carl L. Hansen, Scott Classen, James M. Berger, Stephen R. Quake	2006	151
7	XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair Journal of Biological Chemistry ·Michal Hammel, Martial Rey, Yaping Yu, Rajam S. Mani, Scott Classen, Mona Liu, Michael E. Pique, Shujuan Fang, Brandi L. Mahaney, Michael Weinfeld, David C. Schriemer, Susan P. Lees‐Miller, John A. Tainer	2011	133
8	A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA Molecular Cell ·John M. Pascal, Oleg V. Tsodikov, Greg L. Hura, Wei Song, Elizabeth A. Cotner, Scott Classen, Alan E. Tomkinson, John A. Tainer, Tom Ellenberger	2006	133
9	ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling The EMBO Journal ·Rajashree A. Deshpande, Gareth J. Williams, Oliver Limbo, R. Scott Williams, Jeff Kuhnlein, Ji‐Hoon Lee, Scott Classen, Grant Guenther, Paul Russell, John A. Tainer, Tanya T. Paull	2014	126
10	The R‐factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures FEBS Journal ·James M. Holton, Scott Classen, Kenneth A. Frankel, John A. Tainer	2014	69
11	An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases eLife ·Jeffrey I. Boucher, Joseph R. Jacobowitz, Brian C Beckett, Scott Classen, Douglas L. Theobald	2014	64
12	Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element Nature Structural & Molecular Biology ·In‐Kwon Kim, James R. Kiefer, Chris Ho, Roderick A. Stegeman, Scott Classen, John A. Tainer, Tom Ellenberger	2012	58
13	The Wonders of Flap Endonucleases: Structure, Function, Mechanism and Regulation Sub-cellular biochemistry ·L. David Finger, John M. Atack, Susan E. Tsutakawa, Scott Classen, John A. Tainer, Jane A. Grasby, Binghui Shen	2012	51
14	Software for the high-throughput collection of SAXS data using an enhancedBlu-Ice/DCScontrol system Journal of Synchrotron Radiation ·Scott Classen, Ivan Rodic, James M. Holton, Greg L. Hura, Michal Hammel, John A. Tainer	2010	40
15	Crystal structure of the N-terminal domain of Oxytricha nova telomere end-binding protein α subunit both uncomplexed and complexed with telomeric ssDNA Journal of Molecular Biology ·Scott Classen, James A. Ruggles, Steve C. Schultz	2001	38
16	Sequence-Specific and 3‘-End Selective Single-Strand DNA Binding by the Oxytricha nova Telomere End Binding Protein α Subunit Biochemistry ·Scott Classen, Dan Lyons, Thomas R. Cech, Steve C. Schultz	2003	16
17	Functional and Structural Resilience of the Active Site Loop in the Evolution of Plasmodium Lactate Dehydrogenase Biochemistry ·Jacob D. Wirth, Jeffrey I. Boucher, Joseph R. Jacobowitz, Scott Classen, Douglas L. Theobald	2018	12
18	Visualizing and accessing correlated SAXS data sets with Similarity Maps and Simple Scattering web resources Methods in enzymology on CD-ROM/Methods in enzymology ·Daniel T. Murray, David Shin, Scott Classen, Chris A. Brosey, Greg L. Hura	2022	6
19	Phase behavior and structure formation in ternary blends: studies on blends of PVDF/PMMA/PVAC Polymers for Advanced Technologies ·Scott Classen, Maximilian Vogt, Joachim H. Wendorff	1995	4
20	Predicting RNA structure and dynamics with deep learning and solution scattering Biophysical Journal ·Edan Patt, Scott Classen, Michal Hammel, Dina Schneidman‐Duhovny	2024	2

About Scott Classen

Scott Classen is a scholar working on Molecular Biology, Materials Chemistry, Oncology, Public Health, Environmental and Occupational Health and Structural Biology, having authored 20 papers that have together received 2.0k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (8 papers), Enzyme Structure and Function (6 papers), Protein Structure and Dynamics (5 papers), Genomics and Chromatin Dynamics (3 papers), DNA and Nucleic Acid Chemistry (3 papers), RNA and protein synthesis mechanisms (2 papers), RNA modifications and cancer (2 papers) and Advanced biosensing and bioanalysis techniques (1 paper). The work is most often cited by research in Structural Biology (44 citations), Molecular Biology (1.6k citations), Toxicology (48 citations), Oncology (364 citations) and Cancer Research (131 citations). Scott Classen has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include John A. Tainer, James M. Berger, Stéphane Olland, Greg L. Hura, Michal Hammel, Grant Guenther, Susan E. Tsutakawa, James M. Holton, Robert P. Rambo and Kevin Dyer. Their work appears in journals such as Cell, Biochemistry, Journal of the American Chemical Society, Nature Structural & Molecular Biology and FEBS Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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