Sakthivel Sadayappan

8.0k total citations · 1 hit paper
179 papers, 5.5k citations indexed

About

Sakthivel Sadayappan is a scholar working on Cardiology and Cardiovascular Medicine, Molecular Biology and Surgery. According to data from OpenAlex, Sakthivel Sadayappan has authored 179 papers receiving a total of 5.5k indexed citations (citations by other indexed papers that have themselves been cited), including 141 papers in Cardiology and Cardiovascular Medicine, 96 papers in Molecular Biology and 12 papers in Surgery. Recurrent topics in Sakthivel Sadayappan's work include Cardiomyopathy and Myosin Studies (112 papers), Cardiovascular Effects of Exercise (54 papers) and Muscle Physiology and Disorders (42 papers). Sakthivel Sadayappan is often cited by papers focused on Cardiomyopathy and Myosin Studies (112 papers), Cardiovascular Effects of Exercise (54 papers) and Muscle Physiology and Disorders (42 papers). Sakthivel Sadayappan collaborates with scholars based in United States, United Kingdom and Germany. Sakthivel Sadayappan's co-authors include David Y. Barefield, Jeffrey Robbins, Pieter P. de Tombe, Jeffery D. Molkentin, Michelle A. Sargent, James W. McNamara, Taejeong Song, Jonathan G. Seidman, James Gulick and Hanna Osińska and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Sakthivel Sadayappan

173 papers receiving 5.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An acute immune response underlies the benefit of cardiac stem cell therapy

2019 411 citations Sakthivel Sadayappan et al. profile →

Peers

Sakthivel Sadayappan

CCM

SURGE

PHYSI

Hendrik Milting Germany

Susumu Minamisawa Japan

Diane Fatkin Australia

Michelle A. Sargent United States

Christopher L. Antos Germany

Anthony O. Gramolini Canada

Lucie Carrier Germany

W. Matthijs Blankesteijn Netherlands

Toon A.B. van Veen Netherlands

Anne‐Marie Lompré France

Hendrik Milting Germany

Sakthivel Sadayappan

2.3k ×0.6

CCM

1.7k ×0.5

798 ×1.4

SURGE

426 ×1.2

253 ×0.8

PHYSI

Citations per year, relative to Sakthivel Sadayappan Sakthivel Sadayappan (= 1×) peers Hendrik Milting

Countries citing papers authored by Sakthivel Sadayappan

Since Specialization

Citations

This map shows the geographic impact of Sakthivel Sadayappan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sakthivel Sadayappan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sakthivel Sadayappan more than expected).

Fields of papers citing papers by Sakthivel Sadayappan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sakthivel Sadayappan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sakthivel Sadayappan. The network helps show where Sakthivel Sadayappan may publish in the future.

Co-authorship network of co-authors of Sakthivel Sadayappan

This figure shows the co-authorship network connecting the top 25 collaborators of Sakthivel Sadayappan. A scholar is included among the top collaborators of Sakthivel Sadayappan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sakthivel Sadayappan. Sakthivel Sadayappan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Du, Wa, Chenran Wang, Jun‐Lin Guan, et al.. (2025). Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction. Circulation. 153(9). 653–672.

Qiao, Jun, Lei Jiang, Can Wang, et al.. (2025). Shared genetic architecture contributes to risk of major cardiovascular diseases. Nature Communications. 16(1). 8368–8368. 1 indexed citations

Jani, Vivek, Taejeong Song, Henry Gong, et al.. (2024). The structural OFF and ON states of myosin can be decoupled from the biochemical super- and disordered-relaxed states. PNAS Nexus. 3(2). pgae039–pgae039. 15 indexed citations

Ohayon, Jacques, Diana M. Lindquist, Dipan J. Shah, et al.. (2024). In-silico heart model phantom to validate cardiac strain imaging. Computers in Biology and Medicine. 181. 109065–109065. 7 indexed citations

Song, Taejeong, et al.. (2024). MYBPC3 D389V Variant Induces Hypercontractility in Cardiac Organoids. Cells. 13(22). 1913–1913. 2 indexed citations

Landim-Vieira, Maicon, Weikang Ma, Taejeong Song, et al.. (2023). Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function. Proceedings of the National Academy of Sciences. 120(23). e2221244120–e2221244120. 15 indexed citations

Kumar, Mohit, et al.. (2023). Multiscale characterization of left ventricle active behavior in the mouse. Acta Biomaterialia. 162. 240–253. 10 indexed citations

Nelson, Shane R., Samantha Beck Previs, Sakthivel Sadayappan, Carl Tong, & David M. Warshaw. (2023). Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle. The Journal of General Physiology. 155(4). 14 indexed citations

Li, Amy, Shane R. Nelson, Filip Braet, et al.. (2019). Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems. Proceedings of the National Academy of Sciences. 116(43). 21882–21892. 29 indexed citations

10.

Barefield, David Y., James W. McNamara, Thomas L. Lynch, et al.. (2019). Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 129. 236–246. 20 indexed citations

11.

Kuster, Diederik W.D., Thomas L. Lynch, David Y. Barefield, et al.. (2019). Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy. Cardiovascular Research. 115(14). 1986–1997. 20 indexed citations

12.

Wakimoto, Hiroko, Amanda C. Garfinkel, Barbara McDonough, et al.. (2018). MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy. Circulation Research. 123. 1 indexed citations

13.

Dirkx, Ellen, Freek G. Bouwman, Didier Vertommen, et al.. (2013). Detection of cardiac myosin binding protein-C (cMyBP-C) by a phospho-specific PKD antibody in contracting rat cardiomyocytes. Advances in Bioscience and Biotechnology. 4(4). 1–6. 4 indexed citations

14.

Lin, Brian L., Suresh Govindan, Kyoung Hwan Lee, et al.. (2013). Cardiac Myosin Binding Protein-C Plays No Regulatory Role in Skeletal Muscle Structure and Function. PLoS ONE. 8(7). e69671–e69671. 30 indexed citations

15.

Verma, Suresh K, Prasanna Krishnamurthy, David Y. Barefield, et al.. (2012). Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB. Circulation. 126(4). 418–429. 162 indexed citations

16.

Reinhold, Johannes, Gajen Kanaganayagam, Sakthivel Sadayappan, et al.. (2010). Abstract 15438: Cardiac Myosin-Binding Protein C (cMyBPC) as a Potential New Serum Biomarker of Myocardial Infarction. Circulation. 122. 4 indexed citations

17.

Tong, Carl, Xin Wu, Sakthivel Sadayappan, et al.. (2010). Abstract 16507: Frequency Dependent Phosphorylation of Cardiac Myosin Binding Protein-C Mediates Acceleration of Myocardial Relaxation to Support Normal Diastolic Function. Circulation. 122. 2 indexed citations

18.

Senapathy, Periannan, et al.. (2010). Targeted Genome-Wide Enrichment of Functional Regions. PLoS ONE. 5(6). e11138–e11138. 11 indexed citations

19.

Sadayappan, Sakthivel, James Gulick, Lisa Martin, et al.. (2009). Abstract 3846: Hierarchical and Critical Functions of Ser282 Phosphorylation in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function. Circulation. 120(18). 2 indexed citations

20.

Wang, Hao, et al.. (2006). PKC-βII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144. Journal of Molecular and Cellular Cardiology. 41(5). 823–833. 79 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact