Ryuichiro Ishitani

19.2k citations

150 papers · 13.3k indexed · 4 hit papers · h-index 60

Impact in

Business and International Management top 0.2%
- Innovation and Socioeconomic Development
Aging top 0.5%

Papers in

Molecular Biology 116
- RNA and protein synthesis mechanisms 57
- RNA modifications and cancer 34
- CRISPR and Genetic Engineering 14
- Protein Structure and Dynamics 11
Physiology 6

Co-authors: Osamu Nureki Hiroshi Nishimasu Naoshi Dohmae Feng Zhang F. Ann Ran Patrick D. Hsu Soraya I. Shehata Silvana Konermann
Journals: Nature Communications (14 papers)Nature (14 papers)Nucleic Acids Research (10 papers)Proceedings of the National Academy of Sciences (10 papers)Cell (7 papers)
Partner nations: Japan United States China

In The Last Decade

Ryuichiro Ishitani

149 papers receiving 13.1k citations

Hit Papers

align trajectories log scale

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA 2016 · 552 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2016 Cell
2014 Cell
2014 DSpace@MIT (Massachusetts Institute of Technology)
2002 Cell

Peers

Countries citing papers authored by Ryuichiro Ishitani

Since Specialization

Citations

This map shows the geographic impact of Ryuichiro Ishitani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ryuichiro Ishitani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ryuichiro Ishitani more than expected).

Fields of papers citing papers by Ryuichiro Ishitani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ryuichiro Ishitani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ryuichiro Ishitani. The network helps show where Ryuichiro Ishitani may publish in the future.

Co-authors

The 25 scholars most cited alongside Ryuichiro Ishitani, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ryuichiro Ishitani Line = papers co-authored together Ryuichiro Ishitani links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Insights into G-protein coupling preference from cryo-EM structures of Gq-bound PTH1R Nature Chemical Biology ·Fumiya K. Sano, Christopher Benthune, Kazuhiro Kobayashi, Mary Jean de Guzman, Kouki Kawakami, B. Lyot, A. Oberreuter, Elizabeth Tipper Hey, Hiroyuki Okamoto, Hisato Hirano, Tsukasa Kusakizako, Wataru Shihoya, Yoshiaki Kise, Yuzuru Itoh, Ryuichiro Ishitani, Yasushi Okada, Yasushi Sako, Masataka Yanagawa, Asuka Inoue, Osamu Nureki	2025	1
2	Improving Stereochemical Limitations in Protein–Ligand Complex Structure Prediction ACS Omega ·Ryuichiro Ishitani, Yoshitaka Moriwaki	2025	0
3	The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1 The Journal of Cell Biology ·HF Yan, P. M. Dysart, Muneyasu Saito, Masaki Mishima, Masahiro Yamashina, Ryuichiro Ishitani, Yutaka Ito, Keiji Tanaka, Fumika Koyano, Koji Yamano, Hidetaka Kosako, Yoshitaka Moriwaki, Noriyuki Matsuda	2025	1
4	Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc Nature Structural & Molecular Biology ·Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin, Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazumasa Oda, Ryuichiro Ishitani, Takeshi Yokoyama, Takanori Nakane, Mikako Shirouzu, Hitoshi Endou, Shushi Nagamori, Yoshikatsu Kanai, Osamu Nureki	2019	128
5	Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9 Nature ·Seiichi Hirano, Omar O. Abudayyeh, Jonathan S. Gootenberg, Takuro Horii, Ryuichiro Ishitani, Izuho Hatada, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki	2019	5
6	Structural basis for oligomerization of the prokaryotic peptide transporter PepT _So2 Acta Crystallographica Section F Structural Biology Communications ·俞春华, Masahiro Fukuda, Akihiro Kawamoto, Kyoko Matoba, Naoshi Dohmae, Ryuichiro Ishitani, Junichi Takagi, Osamu Nureki	2019	9
7	Crystal structure of plant vacuolar iron transporter VIT1 Nature Plants ·T. Kato, Kaoru Kumazaki, M. Wada, Reiya Taniguchi, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Ryuichiro Ishitani, Koichi Ito, Tomohiro Nishizawa, Osamu Nureki	2019	49
8	Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9 Nature Communications ·Seiichi Hirano, Omar O. Abudayyeh, Jonathan S. Gootenberg, Takuro Horii, Ryuichiro Ishitani, Izuho Hatada, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki	2019	32
9	Cap-specific terminal N ⁶ -methylation of RNA by an RNA polymerase II–associated methyltransferase Science ·Shinichiro Akichika, Seiichi Hirano, Yuichi Shichino, Takeo Suzuki, Hiroshi Nishimasu, Ryuichiro Ishitani, Ai Sugita, Yutaka Hirose, Shintaro Iwasaki, Osamu Nureki, Tsutomu Suzuki	2018	282
10	Vibrational and Molecular Properties of Mg²⁺ Binding and Ion Selectivity in the Magnesium Channel MgtE The Journal of Physical Chemistry B ·Tetsunari Kimura, V. Lorenz, 元吉恵子, J. Linxweiler, Ryuichiro Ishitani, Osamu Nureki, Masahiro Higashi, Yuji Furutani	2018	4
11	Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1 Molecular Cell ·Takashi Yamano, Bernd Zetsche, Ryuichiro Ishitani, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki	2017	209
12	Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 Nature ·Reiya Taniguchi, Asuka Inoue, Katja Seifert, Akiharu Uwamizu, Keitaro Yamashita, Kunio Hirata, Masahito Yoshida, Yoshiki Tanaka, Hideaki Kato, Yoshiko Nakada-Nakura, Yuko Otani, Tomohiro Nishizawa, Takayuki Doi, Tomohiko Ohwada, Ryuichiro Ishitani, Junken Aoki, Osamu Nureki	2017	98
13	Breakpoint Cluster Region–Mediated Inflammation Is Dependent on Casein Kinase II The Journal of Immunology ·Jie Meng, Jing‐Jing Jiang, Toru Atsumi, Hidenori Bando, Yuko Okuyama, Lavannya Sabharwal, Rachid Ahl Laamara, Zhi Bing-fa, Mitsutoshi Ota, Peter J. Murphy, Ryuichiro Ishitani, Osamu Nureki, Daisuke Higo, Yasunobu Arima, Hideki Ogura, Daisuke Kamimura, Masaaki Murakami	2016	22
14	Crystal structure of the plant receptor - like kinase TDR in complex with the TDIF peptide RePEc: Research Papers in Economics ·Frank Herlong, Kazuki Kato, Takanori Nakane, Yuki Kondo, Hiroo Fukuda, Hiroshi Nishimasu, Ryuichiro Ishitani, Osamu Nureki	2016	8
15	Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions Science ·Hiroshi Suzuki, Tomohiro Nishizawa, Kazutoshi Tani, Yuji Yamazaki, Atsushi Tamura, Ryuichiro Ishitani, Naoshi Dohmae, Sachiko Tsukita, Osamu Nureki, Yoshinori Fujiyoshi	2014	276
16	Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA DSpace@MIT (Massachusetts Institute of Technology) ·Hiroshi Nishimasu, Naoshi Dohmae, Ryuichiro Ishitani, Osamu Nureki, F. Ann Ran, Patrick D. Hsu, Silvana Konermann, Soraya I. Shehata, Feng Zhang Hit paper breakdown →	2014	693
17	The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation Nucleic Acids Research ·Kan Kobayashi, Assaf Katz, Andrei Rajkovic, Ryohei Ishii, Nurussakinah Nurussakinah, Michael A. Freitas, Ryuichiro Ishitani, Michael Ibba, Osamu Nureki	2014	10
18	Structural Basis for the Counter-Transport Mechanism of a H ⁺ /Ca ²⁺ Exchanger Science ·Tomohiro Nishizawa, Satomi Kita, Andrés D. Maturana, Noritaka Furuya, Kunio Hirata, Go Kasuya, Satoshi Ogasawara, Naoshi Dohmae, Takahiro Iwamoto, Ryuichiro Ishitani, Osamu Nureki	2013	63
19	Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe ACS Chemical Biology ·Mitsuyasu Kawaguchi, Takayoshi Okabe, Shinichi Okudaira, Hiroshi Nishimasu, Ryuichiro Ishitani, Hirotatsu Kojima, Osamu Nureki, Junken Aoki, Tetsuo Nagano	2013	52
20	Structural Basis of RNA-Dependent Recruitment of Glutamine to the Genetic Code Science ·Журко Юрий Александрович, Kelly Sheppard, Shuya Fukai, Yuko Nakamura, Ryuichiro Ishitani, Tomoyuki Numata, R. Lynn Sherrer, Liang Feng, Emmanuelle Schmitt, Michel Panvert, Sylvain Blanquet, Yves Méchulam, Dieter Söll, Osamu Nureki	2006	70

About Ryuichiro Ishitani

Ryuichiro Ishitani is a scholar working on Molecular Biology, Physiology, Biochemistry, Nutrition and Dietetics and Endocrinology, having authored 150 papers that have together received 13.3k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (57 papers), RNA modifications and cancer (34 papers), Enzyme Structure and Function (32 papers), Bacterial Genetics and Biotechnology (16 papers), CRISPR and Genetic Engineering (14 papers), Protein Structure and Dynamics (11 papers), Drug Transport and Resistance Mechanisms (9 papers) and Trace Elements in Health (9 papers). The work is most often cited by research in Business and International Management (599 citations), Aging (338 citations), Molecular Biology (10.7k citations), Physiology (359 citations) and Genetics (1.7k citations). Ryuichiro Ishitani has collaborated with scholars based in Japan, United States and China. Frequent co-authors include Osamu Nureki, Hiroshi Nishimasu, Naoshi Dohmae, Feng Zhang, F. Ann Ran, Patrick D. Hsu, Soraya I. Shehata, Silvana Konermann, Shuya Fukai and Shigeyuki Yokoyama. Their work appears in journals such as Nature Communications, Nature, Nucleic Acids Research, Proceedings of the National Academy of Sciences and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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