Hitoshi Endou

33.5k total citations · 5 hit papers
404 papers, 26.1k citations indexed

About

Hitoshi Endou is a scholar working on Molecular Biology, Biochemistry and Oncology. According to data from OpenAlex, Hitoshi Endou has authored 404 papers receiving a total of 26.1k indexed citations (citations by other indexed papers that have themselves been cited), including 198 papers in Molecular Biology, 159 papers in Biochemistry and 127 papers in Oncology. Recurrent topics in Hitoshi Endou's work include Amino Acid Enzymes and Metabolism (153 papers), Drug Transport and Resistance Mechanisms (120 papers) and Metabolism and Genetic Disorders (93 papers). Hitoshi Endou is often cited by papers focused on Amino Acid Enzymes and Metabolism (153 papers), Drug Transport and Resistance Mechanisms (120 papers) and Metabolism and Genetic Disorders (93 papers). Hitoshi Endou collaborates with scholars based in Japan, United States and South Korea. Hitoshi Endou's co-authors include Yoshikatsu Kanai, Takashi Sekine, Naohiko Anzai, Seok Ho, Makoto Hosoyamada, Michio Takeda, Atsushi Enomoto, Arthit Chairoungdua, Yuichi Sugiyama and Hiroyuki Kusuhara and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Journal of Clinical Oncology.

In The Last Decade

Hitoshi Endou

387 papers receiving 25.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Molecular identification of a renal urate–anion exchanger that regulates blood urate levels

2002 1.1k citations Promsuk Jutabha, Michio Takeda et al. profile →
Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

1998 921 citations Yoshikatsu Kanai, Hitoshi Endou et al. profile →
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines

2001 617 citations Jun Inatomi, Isao Okayasu et al. profile →
CATs and HATs: the SLC7 family of amino acid transporters

2004 563 citations Manuel Palacı́n, Hitoshi Endou et al. profile →
Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter

1997 527 citations Yoshikatsu Kanai, Hitoshi Endou et al. profile →

Peers

Countries citing papers authored by Hitoshi Endou

Since Specialization

Citations

This map shows the geographic impact of Hitoshi Endou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hitoshi Endou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hitoshi Endou more than expected).

Fields of papers citing papers by Hitoshi Endou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hitoshi Endou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hitoshi Endou. The network helps show where Hitoshi Endou may publish in the future.

Co-authorship network of co-authors of Hitoshi Endou

This figure shows the co-authorship network connecting the top 25 collaborators of Hitoshi Endou. A scholar is included among the top collaborators of Hitoshi Endou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hitoshi Endou. Hitoshi Endou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Benzbromarone Analog SAR: Potent hURAT1 (SLC22A12) Inhibitors and Drug Transporter Interaction Studies 2025 ·Drug Design Development and Therapy ·Promsuk Jutabha, Vijay Kumar, Naohiko Anzai, Peter J. Rice, Janet Lightner, Hitoshi Endou, Michael F. Wempe	2
2	Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation 2024 ·Journal of Pharmacological Sciences ·Xinyu Zhou, Ryuichi Ohgaki, Chunhuan Jin, Minhui Xu, Hiroki Okanishi, Hitoshi Endou, Yoshikatsu Kanai	4
3	Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells 2024 ·Journal of Pharmacological Sciences ·Yu Ma, Suguru Okuda, Hiroki Okanishi, Minhui Xu, Chunhuan Jin, Hitoshi Endou, Ryuichi Ohgaki, Yoshikatsu Kanai	1
4	Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models 2023 ·Scientific Reports ·Zitong Shi, Kazuko Kaneda‐Nakashima, Ryuichi Ohgaki, Minhui Xu, Hiroki Okanishi, Hitoshi Endou, Shushi Nagamori, Yoshikatsu Kanai	12
5	Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells 2022 ·Journal of Cellular and Molecular Medicine ·(unknown), Ryuichi Ohgaki, Hiroki Okanishi, Suguru Okuda, Minhui Xu, Hitoshi Endou, Yoshikatsu Kanai	23
6	Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer 2020 ·Journal of Clinical Pathology ·Masaaki Ichinoe, Tetuo Mikami, Nobuyuki Yanagisawa, Tsutomu Yoshida, Kiyomi Hana, Hitoshi Endou, Isao Okayasu, (unknown), Hideaki Ogata, Makoto Saegusa, Kazutoshi Shibuya, Yoshiki Murakumo	12
7	Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation 2020 ·Journal of Experimental & Clinical Cancer Research ·Lili Quan, Ryuichi Ohgaki, (unknown), Suguru Okuda, Ling Wei, Hiroki Okanishi, Shushi Nagamori, Hitoshi Endou, Yoshikatsu Kanai	53
8	Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor 2020 ·Cancer Science ·Hiroki Okanishi, Ryuichi Ohgaki, Suguru Okuda, Hitoshi Endou, Yoshikatsu Kanai	21
9	Inhibition of the amino‐acid transporter LAT1 demonstrates anti‐neoplastic activity in medulloblastoma 2019 ·Journal of Cellular and Molecular Medicine ·Yann Cormerais, (unknown), (unknown), Sandy Giuliano, Éric Tambutté, Hitoshi Endou, Michael F. Wempe, Gilles Pagès, Jacques Pouysségur, Vincent Picco	37
10	Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc 2019 ·Nature Structural & Molecular Biology ·Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin, Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazumasa Oda, Ryuichiro Ishitani, Takeshi Yokoyama, Takanori Nakane, Mikako Shirouzu, Hitoshi Endou, Shushi Nagamori, Yoshikatsu Kanai, Osamu Nureki	128
11	Gene cloning and thermal properties of isocitrate dehydrogenase isozymes from a psychrotrophic bacterium, Psychrobacter okhotskensis 2018 ·Yuki Matsumoto, Toshiaki Aoshima, Hitoshi Endou, Yasuhiro Takada	1
12	Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth 2016 ·Cancer Research ·Yann Cormerais, Sandy Giuliano, Renaud LeFloch, (unknown), Jérôme Durivault, Éric Tambutté, (unknown), Laura Rodríguez de la Ballina, Hitoshi Endou, Michael F. Wempe, Manuel Palacı́n, Scott K. Parks, Jacques Pouysségur	140
13	High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas 2012 ·Journal of Clinical Pathology ·Nobuyuki Yanagisawa, Masaaki Ichinoe, Tetuo Mikami, Norihiro Nakada, Kiyomi Hana, Wasaburo Koizumi, Hitoshi Endou, Isao Okayasu	64
14	Human Drug Transporter Gene-expressing Cells are Useful Alternatives to Predict Pharmacokinetics in Man 2011 ·Naohiko Anzai, Shin Wakui, Promsuk Jutabha, Tomoko Muto, (unknown), Keitaro Hayashi, (unknown), Kohsuke Uchida, Michael F. Wempe, Hitoshi Endou	1
15	Human urate transporter 1 (URAT1) mediates orotic acid transport 2007 ·Naohiko Anzai, Daisaku Miura, (unknown), Hitoshi Endou, Yoshikatsu Kanai	1
16	Characterization of Human Orgnic Anion Transporter 4 (hOAT4) as a Low Affinity p-aminohippurate (PAH) Transporter 2007 ·Md. Rafiqul Islam, Naohiko Anzai, (unknown), (unknown), Chun Ji Jin, (unknown), (unknown), (unknown), Toshiyuki Fukutomi, Yoshikatsu Kanai, Hitoshi Endou	2
17	New insights into renal transport of urate 2007 ·Current Opinion in Rheumatology ·Naohiko Anzai, Yoshikatsu Kanai, Hitoshi Endou	140
18	Expression of Human Organic Anion Transporters in the Choroid Plexus and Their Interactions With Neurotransmitter Metabolites 2003 ·SHILAP Revista de lepidopterología ·M. Alebouyeh, Michio Takeda, Maristela L. Onozato, Akihiro Tojo, Rie Noshiro, Habib Hasannejad, Jun Inatomi, Shinichi Narikawa, Xiu-Lin Huang, Suparat Khamdang, Naohiko Anzai, Hitoshi Endou	1
19	Pharmacology. The Bridge to the 21st Century. Molecular mechanisms of drug transport. 2000 ·Folia Pharmacologica Japonica ·Hitoshi Endou	3
20	MICROPUNCTURE STUDY OF PROTEIN CONCENTRATION IN GLOMERULAR FLUID IN THE NEWT 1971 ·The Japanese Journal of Pharmacology ·Hitoshi Endou, Fuminori Sakai	0

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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