Yoshikatsu Kanai

37.4k total citations · 9 hit papers
324 papers, 27.9k citations indexed

About

Yoshikatsu Kanai is a scholar working on Biochemistry, Molecular Biology and Clinical Biochemistry. According to data from OpenAlex, Yoshikatsu Kanai has authored 324 papers receiving a total of 27.9k indexed citations (citations by other indexed papers that have themselves been cited), including 203 papers in Biochemistry, 201 papers in Molecular Biology and 75 papers in Clinical Biochemistry. Recurrent topics in Yoshikatsu Kanai's work include Amino Acid Enzymes and Metabolism (202 papers), Epigenetics and DNA Methylation (118 papers) and Metabolism and Genetic Disorders (75 papers). Yoshikatsu Kanai is often cited by papers focused on Amino Acid Enzymes and Metabolism (202 papers), Epigenetics and DNA Methylation (118 papers) and Metabolism and Genetic Disorders (75 papers). Yoshikatsu Kanai collaborates with scholars based in Japan, United States and South Korea. Yoshikatsu Kanai's co-authors include Hitoshi Endou, Matthias A. Hediger, Takashi Sekine, Seok Ho, Arthit Chairoungdua, Naohiko Anzai, Makoto Hosoyamada, Manuel Palacı́n, Hiroko Segawa and Shushi Nagamori and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Yoshikatsu Kanai

320 papers receiving 27.4k citations

Hit Papers

Knockout of Glutamate Transporters Reveals a Major Role f... 1992 2026 2003 2014 1996 1992 2002 1998 1994 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate
    1996 2.1k citations Yoshikatsu Kanai, Matthias A. Hediger et al. profile →
  2. Primary structure and functional characterization of a high-affinity glutamate transporter
    1992 1.1k citations Yoshikatsu Kanai, Matthias A. Hediger profile →
  3. Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
    2002 1.1k citations Arthit Chairoungdua, Promsuk Jutabha et al. profile →
  4. Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)
    1998 921 citations Yoshikatsu Kanai, Hiroko Segawa et al. Journal of Biological Chemistry profile →
  5. Expression cloning of a mammalian proton-coupled oligopeptide transporter
    1994 748 citations Yoshikatsu Kanai, Matthias A. Hediger et al. profile →
  6. CATs and HATs: the SLC7 family of amino acid transporters
    2004 563 citations Hitoshi Endou, Yoshikatsu Kanai et al. Pflügers Archiv - European Journal of Physiology profile →
  7. The SLC3 and SLC7 families of amino acid transporters
    2013 531 citations Yoshikatsu Kanai et al. profile →
  8. Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter
    1997 527 citations Yoshikatsu Kanai, Hitoshi Endou et al. Journal of Biological Chemistry profile →
  9. Amino acid transporters revisited: New views in health and disease
    2018 337 citations Gergely Gyimesi, Yoshikatsu Kanai et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Yoshikatsu Kanai Japan 85 13.3k 10.6k 6.7k 5.0k 3.8k 324 27.9k
Hitoshi Endou Japan 89 10.9k 0.8× 8.2k 0.8× 9.1k 1.4× 1.5k 0.3× 4.1k 1.1× 404 26.1k
Matthias A. Hediger United States 90 14.8k 1.1× 4.8k 0.5× 4.0k 0.6× 5.9k 1.2× 1.6k 0.4× 256 33.5k
Hermann Koepsell Germany 71 6.7k 0.5× 2.8k 0.3× 7.4k 1.1× 2.3k 0.5× 1.8k 0.5× 233 19.1k
Ronald J. A. Wanders Netherlands 102 32.0k 2.4× 4.3k 0.4× 2.3k 0.3× 1.4k 0.3× 14.8k 3.9× 828 42.4k
Andrew P. Halestrap United Kingdom 97 22.5k 1.7× 2.5k 0.2× 2.6k 0.4× 4.1k 0.8× 3.7k 1.0× 228 35.3k
William C. Sessa United States 112 21.5k 1.6× 4.4k 0.4× 2.4k 0.3× 2.1k 0.4× 584 0.2× 336 46.8k
António Zorzano Spain 78 14.6k 1.1× 4.9k 0.5× 1.3k 0.2× 1.8k 0.4× 3.3k 0.9× 345 23.0k
Ernest M. Wright United States 84 13.2k 1.0× 3.0k 0.3× 2.8k 0.4× 2.7k 0.5× 858 0.2× 289 22.9k
Walter Wahli Switzerland 96 28.5k 2.1× 3.8k 0.4× 3.0k 0.5× 1.8k 0.4× 1.2k 0.3× 325 42.0k
Manuel Palacı́n Spain 67 10.7k 0.8× 5.8k 0.5× 1.4k 0.2× 1.3k 0.3× 3.2k 0.9× 255 17.1k

Countries citing papers authored by Yoshikatsu Kanai

Since Specialization
Citations

This map shows the geographic impact of Yoshikatsu Kanai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yoshikatsu Kanai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yoshikatsu Kanai more than expected).

Fields of papers citing papers by Yoshikatsu Kanai

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yoshikatsu Kanai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yoshikatsu Kanai. The network helps show where Yoshikatsu Kanai may publish in the future.

Co-authorship network of co-authors of Yoshikatsu Kanai

This figure shows the co-authorship network connecting the top 25 collaborators of Yoshikatsu Kanai. A scholar is included among the top collaborators of Yoshikatsu Kanai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yoshikatsu Kanai. Yoshikatsu Kanai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hoshi, Namiko, Yuta Inoue, Makoto Ooi, et al.. (2025). The role of LAT1 in AOM/DSS-induced colorectal tumorigenesis. Biochemical and Biophysical Research Communications. 751. 151446–151446. 1 indexed citations
2.
Ma, Yu, Suguru Okuda, Hiroki Okanishi, et al.. (2024). Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells. Journal of Pharmacological Sciences. 155(1). 14–20. 1 indexed citations
3.
Shi, Zitong, Kazuko Kaneda‐Nakashima, Ryuichi Ohgaki, et al.. (2023). Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models. Scientific Reports. 13(1). 13943–13943. 12 indexed citations
4.
Kurozumi, Sasagu, Kyoichi Kaira, Hiroshi Matsumoto, et al.. (2022). Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer. Scientific Reports. 12(1). 2742–2742. 29 indexed citations
5.
Kongpracha, Pornparn, Pattama Wiriyasermkul, Noriyoshi Isozumi, et al.. (2022). Simple But Efficacious Enrichment of Integral Membrane Proteins and Their Interactions for In-Depth Membrane Proteomics. Molecular & Cellular Proteomics. 21(5). 100206–100206. 20 indexed citations
6.
Ohgaki, Ryuichi, Hiroki Okanishi, Suguru Okuda, et al.. (2022). Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells. Journal of Cellular and Molecular Medicine. 26(20). 5246–5256. 23 indexed citations
7.
Fukui, Kenji, Yuki Fujii, T. Murakawa, et al.. (2022). Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8. Journal of Structural Biology. 214(4). 107904–107904. 1 indexed citations
8.
Quan, Lili, Ryuichi Ohgaki, Suguru Okuda, et al.. (2020). Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation. Journal of Experimental & Clinical Cancer Research. 39(1). 266–266. 53 indexed citations
9.
Kaneda‐Nakashima, Kazuko, Zijian Zhang, Yoshiyuki Manabe, et al.. (2020). α‐Emitting cancer therapy using 211At‐AAMT targeting LAT1. Cancer Science. 112(3). 1132–1140. 35 indexed citations
10.
Okanishi, Hiroki, Ryuichi Ohgaki, Suguru Okuda, Hitoshi Endou, & Yoshikatsu Kanai. (2020). Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor. Cancer Science. 112(2). 871–883. 21 indexed citations
11.
Gyimesi, Gergely, Jonai Pujol‐Giménez, Yoshikatsu Kanai, & Matthias A. Hediger. (2020). Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application. Pflügers Archiv - European Journal of Physiology. 472(9). 1177–1206. 78 indexed citations
12.
Kaira, Kyoichi, Osamu Kawashima, Kazuyoshi Imaizumi, et al.. (2018). Expression of amino acid transporter (LAT1 and 4F2hc) in pulmonary pleomorphic carcinoma. Human Pathology. 84. 142–149. 32 indexed citations
13.
14.
Mori, Yasuo, Shigeki Kiyonaka, & Yoshikatsu Kanai. (2011). Transportsomes and channelsomes: Are they functional units for physiological responses?. Channels. 5(5). 387–390. 7 indexed citations
15.
Miyagi, Kyoko, Shigeki Kiyonaka, Kazunori Yamada, et al.. (2009). A Pathogenic C Terminus-truncated Polycystin-2 Mutant Enhances Receptor-activated Ca2+ Entry via Association with TRPC3 and TRPC7. Journal of Biological Chemistry. 284(49). 34400–34412. 30 indexed citations
16.
Kanai, Yoshikatsu. (2008). Expression of Amino Acid Transporters in Cancers and Their Application to Cancer Diagnosis and Therapuitics. MEMBRANE. 33(3). 108–117. 1 indexed citations
17.
Ito, Kousei, Masashi Honma, Yuki Ikebuchi, et al.. (2008). Posttranslational regulation of Abcc2 expression by SUMOylation system. American Journal of Physiology-Gastrointestinal and Liver Physiology. 296(2). G406–G413. 19 indexed citations
18.
Anzai, Naohiko, Promsuk Jutabha, Yoshikatsu Kanai, & Hitoshi Endou. (2005). Integrated physiology of proximal tubular organic anion transport. Current Opinion in Nephrology & Hypertension. 14(5). 472–479. 35 indexed citations
19.
Kim, Do Kyung, Yoshikatsu Kanai, Hye Won Choi, et al.. (2002). Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1565(1). 112–122. 119 indexed citations
20.
Segawa, Hiroko, Yoshiki Fukasawa, Ken‐ichi Miyamoto, et al.. (1999). Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity. Journal of Biological Chemistry. 274(28). 19745–19751. 430 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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