Ruth Isserlin

15.2k total citations · 4 hit papers
40 papers, 4.7k citations indexed

About

Ruth Isserlin is a scholar working on Molecular Biology, Spectroscopy and Cancer Research. According to data from OpenAlex, Ruth Isserlin has authored 40 papers receiving a total of 4.7k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Molecular Biology, 10 papers in Spectroscopy and 5 papers in Cancer Research. Recurrent topics in Ruth Isserlin's work include Bioinformatics and Genomic Networks (13 papers), Advanced Proteomics Techniques and Applications (10 papers) and Gene expression and cancer classification (5 papers). Ruth Isserlin is often cited by papers focused on Bioinformatics and Genomic Networks (13 papers), Advanced Proteomics Techniques and Applications (10 papers) and Gene expression and cancer classification (5 papers). Ruth Isserlin collaborates with scholars based in Canada, United States and Australia. Ruth Isserlin's co-authors include Gary D. Bader, Daniele Merico, Andrew Emili, Oliver Stueker, Mike Kucera, Changjiang Xu, Jüri Reimand, Mona Meyer, Lina Wadi and Véronique Voisin and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ruth Isserlin

40 papers receiving 4.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

2010 1.5k citations Daniele Merico, Ruth Isserlin et al. PLoS ONE profile →
Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap

2019 1.1k citations Ruth Isserlin, Daniele Merico et al. profile →
Single-cell transcriptomic profiling of the aging mouse brain

2019 439 citations Methodios Ximerakis, Scott Lipnick et al. Nature Neuroscience profile →
A Call for Systematic Research on Solute Carriers

2015 423 citations Ruth Isserlin, A.M. Edwards et al. profile →

Peers

Countries citing papers authored by Ruth Isserlin

Since Specialization

Citations

This map shows the geographic impact of Ruth Isserlin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruth Isserlin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruth Isserlin more than expected).

Fields of papers citing papers by Ruth Isserlin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruth Isserlin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruth Isserlin. The network helps show where Ruth Isserlin may publish in the future.

Co-authorship network of co-authors of Ruth Isserlin

This figure shows the co-authorship network connecting the top 25 collaborators of Ruth Isserlin. A scholar is included among the top collaborators of Ruth Isserlin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ruth Isserlin. Ruth Isserlin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Control of tissue development and cell diversity by cell cycle-dependent transcriptional filtering 2021 ·eLife ·Maria Abou Chakra, Ruth Isserlin, Thinh Ngoc Tran, Gary D. Bader	9
2	Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer 2021 ·Scientific Reports ·(unknown), Misha Bilenky, Alastair Davies, Ruth Isserlin, Gary D. Bader, Neil Fleshner, Martin Hirst, Amina Zoubeidi, Bharati Bapat	12
3	netDx: interpretable patient classification using integrated patient similarity networks 2019 ·Molecular Systems Biology ·Shraddha Pai, Shirley Hui, Ruth Isserlin, (unknown), (unknown), Gary D. Bader	58
4	Single-cell transcriptomic profiling of the aging mouse brain breakdown → 2019 ·Nature Neuroscience ·Methodios Ximerakis, Scott Lipnick, Brendan T. Innes, Sean Simmons, Xian Adiconis, Danielle Dionne, (unknown), Lan Nguyễn, Zachary Niziolek, Ceren Ozek, Vincent L. Butty, Ruth Isserlin, Sean M. Buchanan, Stuart S. Levine, Aviv Regev, Gary D. Bader, Joshua Z. Levin, Lee L. Rubin	439
5	Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression 2019 ·Clinical Epigenetics ·(unknown), Ruth Isserlin, Theodorus van der Kwast, Alexandre R. Zlotta, Gary D. Bader, Neil Fleshner, Bharati Bapat	31
6	Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells 2019 ·Journal of Neuro-Oncology ·Parvez Vora, Mathieu Seyfrid, Chitra Venugopal, Maleeha Qazi, (unknown), Ruth Isserlin, Minomi Subapanditha, (unknown), Sujeivan Mahendram, Mohini Singh, David Bakhshinyan, Chirayu Chokshi, Nicole McFarlane, Anna Dvorkin‐Gheva, Kevin R. Brown, Naresh Murty, Jason Moffat, Gary D. Bader, Sheila K. Singh	19
7	Integrative Cancer Pharmacogenomics to Infer Large-Scale Drug Taxonomy 2017 ·Cancer Research ·Nehmé El-Hachem, Deena M.A. Gendoo, Laleh Soltan Ghoraie, Zhaleh Safikhani, Petr Smirnov, Christina Chung, (unknown), (unknown), (unknown), (unknown), Ruth Isserlin, Gary D. Bader, Anna Goldenberg, Benjamin Haibe‐Kains	28
8	Exercise-responsive phosphoproteins in the heart 2017 ·Journal of Molecular and Cellular Cardiology ·Hongbo Guo, Ruth Isserlin, Andrew Emili, Jatin G. Burniston	12
9	Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis 2016 ·Clinical Epigenetics ·(unknown), Linh Ho, Ken J. Kron, Ruth Isserlin, Theodorus van der Kwast, Alexandre R. Zlotta, Neil Fleshner, Gary D. Bader, Bharati Bapat	21
10	Systems analysis reveals down-regulation of a network of pro-survival miRNAs drives the apoptotic response in dilated cardiomyopathy 2014 ·Molecular BioSystems ·Ruth Isserlin, Daniele Merico, Dingyan Wang, Dajana Vuckovic, Nicolas Bousette, Anthony O. Gramolini, Gary D. Bader, Andrew Emili	21
11	Discovery of Novel Disease-specific and Membrane-associated Candidate Markers in a Mouse Model of Multiple Sclerosis 2013 ·Molecular & Cellular Proteomics ·Laura F. Dagley, Nathan P. Croft, Ruth Isserlin, Jonathan B. Olsen, Vincent Fong, Andrew Emili, Anthony W. Purcell	12
12	Global Proteomic Profiling and Enrichment Maps of Dilated Cardiomyopathy 2013 ·Methods in molecular biology ·Ruth Isserlin, Daniele Merico, Andrew Emili	1
13	Too many roads not taken 2011 ·Nature ·A.M. Edwards, Ruth Isserlin, Gary D. Bader, Stephen V. Frye, Timothy M. Willson, Frank H. Yu	273
14	WordCloud: a Cytoscape plugin to create a visual semantic summary of networks 2011 ·SHILAP Revista de lepidopterología ·Layla Oesper, Daniele Merico, Ruth Isserlin, Gary D. Bader	110
15	Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation breakdown → 2010 ·PLoS ONE ·Daniele Merico, Ruth Isserlin, Oliver Stueker, Andrew Emili, Gary D. Bader	1512
16	Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps 2010 ·PROTEOMICS ·Ruth Isserlin, Daniele Merico, (unknown), Anthony O. Gramolini, Gary D. Bader, Andrew Emili	49
17	A Lentiviral Functional Proteomics Approach Identifies Chromatin Remodeling Complexes Important for the Induction of Pluripotency 2010 ·Molecular & Cellular Proteomics ·Anthony B. Mak, Zuyao Ni, Johannes A. Hewel, Ginny I. Chen, Guoqing Zhong, Konstantina Karamboulas, (unknown), (unknown), Edyta Marcon, (unknown), Joyce Li, Jonathan B. Olsen, Cuihong Wan, (unknown), Ruth Isserlin, Sergei Chetyrkin, Anne‐Claude Gingras, Andrew Emili, Jack Greenblatt, Jason Moffat	65
18	Nine steps to proteomic wisdom: A practical guide to using protein‐protein interaction networks and molecular pathways as a framework for interpreting disease proteomic profiles 2007 ·PROTEOMICS - CLINICAL APPLICATIONS ·Ruth Isserlin, Andrew Emili	4
19	Analysis of domain correlations in yeast protein complexes 2004 ·Bioinformatics ·Doron Betel, Ruth Isserlin, Christopher W.V. Hogue	11
20	SeqHound: biological sequence and structure database as a platform for bioinformatics research 2002 ·BMC Bioinformatics ·Katerina Michalickova, Gary D. Bader, Michel Dumontier, (unknown), Doron Betel, Ruth Isserlin, Christopher W.V. Hogue	39

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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