Ronald J. Mandel

15.3k citations

95 papers · 12.2k indexed · 5 hit papers · h-index 50

Molecular Biology top 0.5%
Cellular and Molecular Neuroscience top 0.2%
Genetics top 0.2%
Neurology top 0.2%
Physiology top 2%

Co-authors: Didier Trono Romain Zufferey Luigi Naldini Corinna Bürger Nicholas Muzyczka Anders Björklund Deniz Kirik Minh Nguyen
Topics: Virus-based gene therapy research (40 papers)Nerve injury and regeneration (37 papers)Parkinson's Disease Mechanisms and Treatments (22 papers)
Cited by: Cellular and Molecular Neuroscience Neurology Developmental Neuroscience
Journals: Proceedings of the National Academy of Sciences Neuron Journal of Neuroscience
Partner nations: United States Sweden United Kingdom

In The Last Decade

Ronald J. Mandel

95 papers receiving 12.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Third-Generation Lentivirus Vector with a Conditional Packaging System

1998 2.5k citations Ronald J. Mandel et al. profile →
Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

1998 1.5k citations Ronald J. Mandel et al. profile →
Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System

2004 597 citations Corinna Bürger, Carmen S. Peden et al. Molecular Therapy profile →
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

2002 550 citations Deniz Kirik, Carl Rosenblad et al. PubMed profile →
Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System

2002 519 citations Deniz Kirik, Carl Rosenblad et al. Journal of Neuroscience profile →

Peers

Countries citing papers authored by Ronald J. Mandel

Since Specialization

Citations

This map shows the geographic impact of Ronald J. Mandel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ronald J. Mandel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ronald J. Mandel more than expected).

Fields of papers citing papers by Ronald J. Mandel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ronald J. Mandel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ronald J. Mandel. The network helps show where Ronald J. Mandel may publish in the future.

Co-authorship network of co-authors of Ronald J. Mandel

This figure shows the co-authorship network connecting the top 25 collaborators of Ronald J. Mandel. A scholar is included among the top collaborators of Ronald J. Mandel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ronald J. Mandel. Ronald J. Mandel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Site-specific modifications to AAV8 capsid yields enhanced brain transduction in the neonatal MPS IIIB mouse 2020 ·Gene Therapy ·(unknown),(unknown),(unknown),Ronald J. Mandel,Sanford L. Boye,Arun Srivastava,Coy D. Heldermon	12
2	The Future of GDNF in Parkinson's Disease 2020 ·Frontiers in Aging Neuroscience ·Fredric P. Manfredsson,Nicole K. Polinski,Thyagarajan Subramanian,Nicholas M. Boulis,Dustin R. Wakeman,Ronald J. Mandel	33
3	Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease 2019 ·Experimental Neurology ·(unknown),Macarena Vergara,José A. Pino,(unknown),Habibeh Khoshbouei,Ronald J. Mandel,Gonzalo E. Torres	88
4	Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates 2017 ·Acta Neuropathologica Communications ·Ronald J. Mandel,David J. Marmion,Deniz Kirik,Yaping Chu,Clifford Heindel,Thomas J. McCown,Steven J. Gray,Jeffrey H. Kordower	37
5	Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways 2014 ·Gene Therapy ·Sara E. Gombash,Fredric P. Manfredsson,Ronald J. Mandel,Timothy J. Collier,D. Luke Fischer,Christopher J. Kemp,(unknown),Susan L. Wohlgenant,Sheila M. Fleming,Caryl E. Sortwell	25
6	Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model 2011 ·Molecular Therapy ·Sara E. Gombash,Jack W. Lipton,Timothy J. Collier,Lalitha Madhavan,Kathy Steece‐Collier,Allyson Cole-Strauss,Brian T. Terpstra,Anne L. Spieles-Engemann,Brian F. Daley,Susan L. Wohlgenant,(unknown),Fredric P. Manfredsson,Ronald J. Mandel,Caryl E. Sortwell	27
7	Striatal Readministration of rAAV Vectors Reveals an Immune Response Against AAV2 Capsids That Can Be Circumvented 2009 ·Molecular Therapy ·Carmen S. Peden,Fredric P. Manfredsson,Sharon Reimsnider,Amy Poirier,Corinna Bürger,Nicholas Muzyczka,Ronald J. Mandel	39
8	Sustained striatal ciliary neurotrophic factor expression negatively affects behavior and gene expression in normal and R6/1 mice 2008 ·Journal of Neuroscience Research ·Eileen M. Denovan‐Wright,(unknown),Edgardo Rodríguez-Lebrón,Ronald J. Mandel	11
9	Viral vectors for in vivo gene transfer in Parkinson's disease: Properties and clinical grade production 2007 ·Experimental Neurology ·Ronald J. Mandel,Corinna Bürger,Richard O. Snyder	33
10	LRRK2 mutations in a clinic‐based cohort of Parkinson's disease 2006 ·European Journal of Neurology ·Sonja W. Scholz,Ronald J. Mandel,Hubert H. Fernandez,Kelly D. Foote,Ramon L. Rodriguez,Elisabeth R. Barton,Sarah Munson,A. B. Singleton,Michael S. Okun	6
11	Continuous Low-Level Glial Cell Line-Derived Neurotrophic Factor Delivery Using Recombinant Adeno-Associated Viral Vectors Provides Neuroprotection and Induces Behavioral Recovery in a Primate Model of Parkinson's Disease 2005 ·Journal of Neuroscience ·Andisheh Eslamboli,Biljana Georgievska,R.M. Ridley,Harry F. Baker,Nicholas Muzyczka,Corinna Bürger,Ronald J. Mandel,Lucy E. Annett,Deniz Kirik	189
12	Clinical trials in neurological disorders using AAV vectors: promises and challenges. 2004 ·PubMed ·Ronald J. Mandel,Corinna Bürger	68
13	Gene Therapy for Pyruvate Dehydrogenase E1α Deficiency Using Recombinant Adeno-Associated Virus 2 (rAAV2) Vectors 2002 ·Molecular Therapy ·Renius Owen,Ronald J. Mandel,(unknown),Thomas J. Conlon,Douglas S. Kerr,Peter W. Stacpoole,Terence R. Flotte	11
14	Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model11Published on the World Wide Web on 10 October 2000. 2000 ·Brain Research ·Anders Björklund,Deniz Kirik,Carl Rosenblad,Biljana Georgievska,Cecilia Lundberg,Ronald J. Mandel	274
15	Long-Term rAAV-Mediated Gene Transfer of GDNF in the Rat Parkinson's Model: Intrastriatal But Not Intranigral Transduction Promotes Functional Regeneration in the Lesioned Nigrostriatal System 2000 ·Journal of Neuroscience ·Deniz Kirik,Carl Rosenblad,Anders Björklund,Ronald J. Mandel	342
16	Recombinant Adeno-associated Viral Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Protects Nigral Dopamine Neurons after Onset of Progressive Degeneration in a Rat Model of Parkinson's Disease 1999 ·Experimental Neurology ·Ronald J. Mandel,Richard O. Snyder,Stuart E. Leff	77
17	Viral Gene Delivery Selectively Restores Feeding and Prevents Lethality of Dopamine-Deficient Mice 1999 ·Neuron ·Mark S. Szczypka,Ronald J. Mandel,Brian A. Donahue,Richard O. Snyder,Stuart E. Leff,(unknown)	102
18	Behavioral quantification of striatal dopaminergic supersensitivity after bilateral 6-hydroxydopamine lesions in the mouse 1992 ·Pharmacology Biochemistry and Behavior ·Ronald J. Mandel,Richard E. Wilcox,Patrick K. Randall	9
19	Independent effects of age and nucleus basalis magnocellularis lesion: Maze learning, cortical neurochemistry, and morphometry. 1992 ·Behavioral Neuroscience ·Donald J. Connor,Leon J. Thal,Ronald J. Mandel,Philip J. Langlais,et al	15
20	Spatial learning in rats: Correlation with cortical choline acetyltransferase and improvement with NGF following NBM damage 1989 ·Experimental Neurology ·Ronald J. Mandel,Fred H. Gage,L. J. Thal	105

About Ronald J. Mandel

Ronald J. Mandel is a scholar working on Cellular and Molecular Neuroscience, Neurology and Genetics, having authored 95 papers that have together received 12.2k indexed citations. Recurring topics across this work include Virus-based gene therapy research (40 papers), Nerve injury and regeneration (37 papers) and Parkinson's Disease Mechanisms and Treatments (22 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (4.7k citations), Neurology (3.0k citations) and Developmental Neuroscience (718 citations). Ronald J. Mandel has collaborated with scholars based in United States, Sweden and United Kingdom. Frequent co-authors include Didier Trono, Romain Zufferey, Luigi Naldini, Corinna Bürger, Nicholas Muzyczka, Anders Björklund, Deniz Kirik, Minh Nguyen, Michael T. Kelly and Carl Rosenblad. Their work appears in journals such as Proceedings of the National Academy of Sciences, Neuron and Journal of Neuroscience.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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