Robert T. Manguso

6.8k total citations · 3 hit papers
19 papers, 1.9k citations indexed

About

Robert T. Manguso is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Robert T. Manguso has authored 19 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 9 papers in Immunology and 7 papers in Oncology. Recurrent topics in Robert T. Manguso's work include CAR-T cell therapy research (7 papers), CRISPR and Genetic Engineering (4 papers) and Cancer Immunotherapy and Biomarkers (3 papers). Robert T. Manguso is often cited by papers focused on CAR-T cell therapy research (7 papers), CRISPR and Genetic Engineering (4 papers) and Cancer Immunotherapy and Biomarkers (3 papers). Robert T. Manguso collaborates with scholars based in United States, Denmark and Germany. Robert T. Manguso's co-authors include W. Nicholas Haining, Natalie B. Collins, Vikram R. Juneja, Arlene H. Sharpe, Martin W. LaFleur, Gordon J. Freeman, Kathleen A. McGuire, Kathleen B. Yates, David E. Root and John G. Doench and has published in prestigious journals such as Nature, Cell and Nucleic Acids Research.

In The Last Decade

Robert T. Manguso

17 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

2017 774 citations Robert T. Manguso, Hans W. Pope et al. Nature profile →
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

2017 612 citations Vikram R. Juneja, Kathleen A. McGuire et al. The Journal of Experimental Medicine profile →
Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits

2025 18 citations Loïc Binan, Aiping Jiang et al. Cell profile →

Peers

Countries citing papers authored by Robert T. Manguso

Since Specialization

Citations

This map shows the geographic impact of Robert T. Manguso's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert T. Manguso with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert T. Manguso more than expected).

Fields of papers citing papers by Robert T. Manguso

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert T. Manguso. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert T. Manguso. The network helps show where Robert T. Manguso may publish in the future.

Co-authorship network of co-authors of Robert T. Manguso

This figure shows the co-authorship network connecting the top 25 collaborators of Robert T. Manguso. A scholar is included among the top collaborators of Robert T. Manguso based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert T. Manguso. Robert T. Manguso is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits breakdown → 2025 ·Cell ·Loïc Binan, Aiping Jiang, (unknown), Vera Valakh, Brooke Simonton, (unknown), Robert T. Manguso, Kathleen B. Yates, Ralda Nehme, Brian Cleary, Samouil L. Farhi	18
2	Abstract 34: Improving CAR T cell efficacy in pancreatic cancer using an in vivo CRISPR Cas9 screen 2024 ·Cancer Research ·(unknown), Felix Korell, Nelson H. Knudsen, Kathleen B. Yates, (unknown), Debattama R. Sen, Marcela V. Maus, Robert T. Manguso	0
3	Protocol for in vivo CRISPR screening using selective CRISPR antigen removal lentiviral vectors 2023 ·STAR Protocols ·Sarah Kate Lane-Reticker, Emily Kessler, Audrey J. Muscato, Sarah Kim, John G. Doench, Kathleen B. Yates, Robert T. Manguso, Juan Dubrot	2
4	ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy 2023 ·Genes & Development ·Mingchao Wang, Xiaojuan Ran, Wendy Leung, Ajinkya S. Kawale, Sneha Saxena, Jian Ouyang, Parasvi S. Patel, Yuting Dong, Tao Yin, Jian Shu, Robert T. Manguso, Li Lan, Xiao‐Fan Wang, Michael S. Lawrence, Lee Zou	15
5	A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy 2023 ·Blood ·William M. Lin, (unknown), (unknown), Nelson H. Knudsen, (unknown), (unknown), (unknown), (unknown), (unknown), Amanda A. Bouffard, Marcela V. Maus, Robert T. Manguso, Max Jan	0
6	Extracellular matrix proteins regulate NK cell function in peripheral tissues 2022 ·Science Advances ·Mark D. Bunting, (unknown), Marta Requesens, Adam Langenbucher, (unknown), Robert T. Manguso, Michael S. Lawrence, Shadmehr Demehri	38
7	PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment 2022 ·Journal for ImmunoTherapy of Cancer ·Natalie B. Collins, Rose Al Abosy, Brian C. Miller, Kevin Bi, Qihong Zhao, Michael Quigley, (unknown), Kathleen B. Yates, Hans W. Pope, Robert T. Manguso, Yashaswi Shrestha, Marc H. Wadsworth, Tudor Hughes, Alex K. Shalek, Jesse S. Boehm, William C. Hahn, John G. Doench, W. Nicholas Haining	47
8	Abstract ND06: ABBV-CLS-484: An active site PTPN2/N1 inhibitor that augments the immune response and sensitizes tumors to immune-mediated killing 2022 ·Cancer Research ·Christina K. Baumgartner, Marcia N. Paddock, Jennifer M. Frost, Keith M. Hamel, Kathleen A. McGuire, Kyle Halliwill, (unknown), (unknown), Kelly L. Klinge, Prasanthi Geda, (unknown), Marinka Bulic, Elliot P. Farney, Kathleen B. Yates, Robert T. Manguso, Clay Beauregard, Philip R. Kym	4
9	In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma 2021 ·Immunity ·Juan Dubrot, Sarah Kate Lane-Reticker, Emily Kessler, (unknown), Gargi Mishra, Clara Wolfe, Margaret D. Zimmer, Peter P. Du, (unknown), Kyle Ockerman, Thomas Davis, Ian C. Kohnle, Hans W. Pope, Peter M. Allen, Kira E. Olander, Arvin Iracheta‐Vellve, John G. Doench, W. Nicholas Haining, Kathleen B. Yates, Robert T. Manguso	51
10	TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response 2021 ·Nucleic Acids Research ·Zexian Zeng, (unknown), Lin Yang, (unknown), Dian Li, Wubing Zhang, Shengqing Gu, Yi Zhang, Yang Liu, Xiaoqing Wang, Jingxin Fu, Liye Zhou, Boning Zhang, Sarah Kim, Kathleen B. Yates, Myles Brown, Gordon J. Freeman, Ravindra Uppaluri, Robert T. Manguso, X. Shirley Liu	73
11	Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer 2020 ·Cell Metabolism ·Douglas E. Biancur, Kevin S. Kapner, Keisuke Yamamoto, Robert S. Banh, Jasper E. Neggers, Albert S.W. Sohn, Warren Wu, Robert T. Manguso, Adam Brown, David E. Root, Andrew J. Aguirre, Alec C. Kimmelman	58
12	Abstract 1810: The mutant IDH1 inhibitor ivosidenib promotes tumor cell differentiation and anti-tumor immunity in intrahepatic cholangiocarcinoma 2020 ·Cancer Research ·(unknown), Lei Shi, Juan Dubrot, Christine C. Hudson, (unknown), (unknown), Qibiao Wu, Sébastien Ronseaux, Rohini Narayanaswamy, Robert T. Manguso, Brandon Nicolay, Nabeel Bardeesy	1
13	PI3K activated tumors evade tumor immunity by promoting an inhibitory myeloid microenvironment 2019 ·The Journal of Immunology ·Natalie B. Collins, Rose Al Abosy, Brian C. Miller, Kevin Bi, Robert T. Manguso, Kathleen B. Yates, W. Nicholas Haining	4
14	In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target breakdown → 2017 ·Nature ·Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer, Flavian D. Brown, Kathleen B. Yates, Brian C. Miller, Natalie B. Collins, Kevin Bi, Martin W. LaFleur, Vikram R. Juneja, Sarah A. Weiss, Jennifer A. Lo, David E. Fisher, Diana Miao, Eliezer M. Van Allen, David E. Root, Arlene H. Sharpe, John G. Doench, W. Nicholas Haining	774
15	PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity breakdown → 2017 ·The Journal of Experimental Medicine ·Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso, Martin W. LaFleur, Natalie B. Collins, W. Nicholas Haining, Gordon J. Freeman, Arlene H. Sharpe	612
16	Primary cilia and aberrant cell signaling in epithelial ovarian cancer 2012 ·SHILAP Revista de lepidopterología ·Dorte L Egeberg, (unknown), Robert T. Manguso, Linda Schneider, A. Awan, (unknown), Anne Grete Byskov, Lotte B. Pedersen, Søren T. Christensen	74
17	EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms 2011 ·Journal of Cell Science ·Jacob M. Schrøder, Jesper Larsen, Yulia Komarova, Anna Akhmanova, (unknown), Ilya Grigoriev, Robert T. Manguso, Søren T. Christensen, Stine F. Pedersen, Stefan Geimer, Lotte B. Pedersen	93
18	EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms 2011 ·Development ·Jacob M. Schrøder, Jesper Larsen, Yulia Komarova, Anna Akhmanova, (unknown), Ilya Grigoriev, Robert T. Manguso, Søren T. Christensen, Stine F. Pedersen, Stefan Geimer, Lotte B. Pedersen	1
19	Common variable hypogammaglobulinemia with T-cell nodular lymphoid interstitial pneumonitis and B-cell nodular lymphoid hyperplasia: Different lymphocyte populations with a similar response to prednisone therapy 1982 ·Journal of Allergy and Clinical Immunology ·Peter F. Köhler, (unknown), (unknown), Robert T. Manguso	45

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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