Robert G. Vries

11.3k total citations · 5 hit papers
25 papers, 6.1k citations indexed

About

Robert G. Vries is a scholar working on Molecular Biology, Oncology and Surgery. According to data from OpenAlex, Robert G. Vries has authored 25 papers receiving a total of 6.1k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 11 papers in Oncology and 6 papers in Surgery. Recurrent topics in Robert G. Vries's work include Cancer Cells and Metastasis (10 papers), Liver physiology and pathology (5 papers) and Wnt/β-catenin signaling in development and cancer (4 papers). Robert G. Vries is often cited by papers focused on Cancer Cells and Metastasis (10 papers), Liver physiology and pathology (5 papers) and Wnt/β-catenin signaling in development and cancer (4 papers). Robert G. Vries collaborates with scholars based in Netherlands, United States and United Kingdom. Robert G. Vries's co-authors include Hans Clevers, Marc van de Wetering, Johan H. van Es, Toshiro Sato, Maaike van den Born, Nick Barker, Daniel E. Stange, Hugo J.G. Snippert, Noah F. Shroyer and Meritxell Huch and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Robert G. Vries

23 papers receiving 6.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

2010 1.9k citations Toshiro Sato, Johan H. van Es et al. Nature profile →
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

2013 1.1k citations Meritxell Huch, Craig Dorrell et al. Nature profile →
In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

2014 609 citations Sina Bartfeld, Marc van de Wetering et al. Gastroenterology profile →
Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

2010 585 citations Hugo J.G. Snippert, Andrea Haegebarth et al. Science profile →
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

2013 535 citations Meritxell Huch, Paola Bonfanti et al. The EMBO Journal profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert G. Vries Netherlands	16	3.0k	2.5k	1.2k	1.1k	945	25	6.1k
Nobuo Sasaki Japan	26	3.4k 1.1×	1.8k 0.7×	936 0.8×	869 0.8×	943 1.0×	59	5.9k
Stieneke van den Brink Netherlands	17	3.4k 1.1×	2.7k 1.1×	1.5k 1.3×	1.8k 1.7×	911 1.0×	19	6.9k
Christopher N. Mayhew United States	28	3.1k 1.0×	1.7k 0.7×	1.0k 0.9×	1.4k 1.3×	637 0.7×	60	5.1k
Kenji Kawabata Japan	42	3.6k 1.2×	2.1k 0.8×	1.1k 1.0×	743 0.7×	1.6k 1.7×	182	7.4k
Meritxell Huch United Kingdom	35	4.0k 1.3×	3.1k 1.2×	2.5k 2.1×	2.2k 2.1×	1.3k 1.3×	61	8.7k
Miranda Cozijnsen Netherlands	11	3.3k 1.1×	2.9k 1.1×	771 0.7×	370 0.3×	1.2k 1.3×	13	5.9k
Andrea Haegebarth Germany	24	5.4k 1.8×	4.1k 1.6×	1.1k 0.9×	454 0.4×	1.9k 2.0×	47	9.0k
Mami Matano Japan	18	1.7k 0.6×	2.4k 0.9×	366 0.3×	1.1k 1.0×	517 0.5×	29	4.0k
Henner F. Farin Germany	30	2.3k 0.8×	1.8k 0.7×	492 0.4×	545 0.5×	934 1.0×	47	4.1k
Ruben van Boxtel Netherlands	30	2.7k 0.9×	1.7k 0.7×	329 0.3×	640 0.6×	700 0.7×	84	5.0k

Countries citing papers authored by Robert G. Vries

Since Specialization

Citations

This map shows the geographic impact of Robert G. Vries's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert G. Vries with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert G. Vries more than expected).

Fields of papers citing papers by Robert G. Vries

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert G. Vries. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert G. Vries. The network helps show where Robert G. Vries may publish in the future.

Co-authorship network of co-authors of Robert G. Vries

This figure shows the co-authorship network connecting the top 25 collaborators of Robert G. Vries. A scholar is included among the top collaborators of Robert G. Vries based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert G. Vries. Robert G. Vries is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Ladstätter, Sabrina, René Overmeer, Péter Brázda, et al.. (2025). Single‐cell multi‐omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying CRC ‐unique features. International Journal of Cancer. 157(12). 2619–2634.

2.

Wensink, G. Emerens, Carla S. Veríssimo, Esmee Koedoot, et al.. (2024). Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response. Journal of Experimental & Clinical Cancer Research. 43(1). 61–61. 26 indexed citations

3.

Veríssimo, Carla S., G. Emerens Wensink, Esmee Koedoot, et al.. (2023). Abstract 151: Optimization of screening conditions using patient-derived organoids for diagnostic purposes. Cancer Research. 83(7_Supplement). 151–151.

4.

Jelinsky, Scott A., Eric B. Bauman, Carla S. Veríssimo, et al.. (2022). Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier. Inflammatory Bowel Diseases. 29(2). 195–206. 35 indexed citations

5.

Veríssimo, Carla S., et al.. (2021). Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function. Journal of Visualized Experiments. 14 indexed citations

6.

Veríssimo, Carla S., et al.. (2021). Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function. Journal of Visualized Experiments. 4 indexed citations

7.

Tüysüz, Nesrin, Louis van Bloois, Stieneke van den Brink, et al.. (2017). Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells. Nature Communications. 8(1). 14578–14578. 59 indexed citations

8.

Schutgens, Frans, Maarten B. Rookmaaker, Francis Blokzijl, et al.. (2017). Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney. Proceedings of the National Academy of Sciences. 114(52). E11190–E11198. 18 indexed citations

9.

Pont, Margot J., M. Willy Honders, Anita N. Kremer, et al.. (2016). Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies. PLoS ONE. 11(5). e0155165–e0155165. 13 indexed citations

10.

Weeber, Fleur, Marc van de Wetering, Marlous Hoogstraat, et al.. (2015). Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases. Proceedings of the National Academy of Sciences. 112(43). 13308–13311. 349 indexed citations

11.

Bartfeld, Sina, Marc van de Wetering, Meritxell Huch, et al.. (2014). In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection. Gastroenterology. 148(1). 126–136.e6. 609 indexed citations breakdown →

12.

Huch, Meritxell, Paola Bonfanti, Sylvia F. Boj, et al.. (2013). Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. The EMBO Journal. 32(20). 2708–2721. 535 indexed citations breakdown →

13.

Huch, Meritxell, Craig Dorrell, Sylvia F. Boj, et al.. (2013). In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature. 494(7436). 247–250. 1149 indexed citations breakdown →

14.

Schepers, Arnout, Robert G. Vries, Maaike van den Born, Marc van de Wetering, & Hans Clevers. (2011). Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes. The EMBO Journal. 30(6). 1104–1109. 165 indexed citations

15.

Snippert, Hugo J.G., Andrea Haegebarth, Maria Kasper, et al.. (2010). Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin. Science. 327(5971). 1385–1389. 585 indexed citations breakdown →

16.

Mahmoudi, Tokameh, Sylvia F. Boj, Pantelis Hatzis, et al.. (2010). The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis. PLoS Biology. 8(11). e1000539–e1000539. 63 indexed citations

17.

Sato, Toshiro, Johan H. van Es, Hugo J.G. Snippert, et al.. (2010). Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature. 469(7330). 415–418. 1863 indexed citations breakdown →

18.

McLeod, Laura E., et al.. (2002). Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors. European Journal of Biochemistry. 269(12). 3076–3085. 144 indexed citations

19.

Wang, Xuemin, Andrea Flynn, Andrew J. Waskiewicz, et al.. (1998). The Phosphorylation of Eukaryotic Initiation Factor eIF4E in Response to Phorbol Esters, Cell Stresses, and Cytokines Is Mediated by Distinct MAP Kinase Pathways. Journal of Biological Chemistry. 273(16). 9373–9377. 258 indexed citations

20.

Vries, Robert G., et al.. (1997). Heat Shock Increases the Association of Binding Protein-1 with Initiation Factor 4E. Journal of Biological Chemistry. 272(52). 32779–32784. 67 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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