Robert D. Leone

3.3k total citations · 2 hit papers
34 papers, 2.5k citations indexed

About

Robert D. Leone is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Robert D. Leone has authored 34 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 10 papers in Immunology and 7 papers in Oncology. Recurrent topics in Robert D. Leone's work include Immune Cell Function and Interaction (7 papers), Cancer, Hypoxia, and Metabolism (6 papers) and Adenosine and Purinergic Signaling (5 papers). Robert D. Leone is often cited by papers focused on Immune Cell Function and Interaction (7 papers), Cancer, Hypoxia, and Metabolism (6 papers) and Adenosine and Purinergic Signaling (5 papers). Robert D. Leone collaborates with scholars based in United States, Canada and Italy. Robert D. Leone's co-authors include Leisha A. Emens, Jonathan D. Powell, Chirag H. Patel, Min Hee Oh, Judson M. Englert, Jiayu Wen, Im‐Hong Sun, Barbara S. Slusher, Liang Zhao and Rana Rais and has published in prestigious journals such as Science, Nature Communications and Journal of Clinical Oncology.

In The Last Decade

Robert D. Leone

34 papers receiving 2.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

2019 813 citations Robert D. Leone, Liang Zhao et al. Science profile →
Targeting adenosine for cancer immunotherapy

2018 417 citations Robert D. Leone, Leisha A. Emens Journal for ImmunoTherapy of Cancer profile →

Peers

Countries citing papers authored by Robert D. Leone

Since Specialization

Citations

This map shows the geographic impact of Robert D. Leone's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert D. Leone with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert D. Leone more than expected).

Fields of papers citing papers by Robert D. Leone

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert D. Leone. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert D. Leone. The network helps show where Robert D. Leone may publish in the future.

Co-authorship network of co-authors of Robert D. Leone

This figure shows the co-authorship network connecting the top 25 collaborators of Robert D. Leone. A scholar is included among the top collaborators of Robert D. Leone based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert D. Leone. Robert D. Leone is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	QRICH1 mediates an intracellular checkpoint for CD8 ⁺ T cell activation via the CARD11 signalosome 2025 ·Science Immunology ·Nicole Carter, (unknown), Yongkang Yang, Chao Yang, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Robert D. Leone, Joel L. Pomerantz	1
2	Analysis of Processes for Olive Oil Mill Wastewater Treatment 2025 ·Journal of Information Systems Engineering & Management ·Robert D. Leone	1
3	E-Cadherin Induces Serine Synthesis to Support Progression and Metastasis of Breast Cancer 2024 ·Cancer Research ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Jung-Woo Kim, (unknown), Cholsoon Jang, Moonjung Jung, Robert D. Leone, Κωνσταντίνος Κωνσταντόπουλος, Andrew J. Ewald, Denis Wirtz, Sangmoo Jeong	13
4	Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis 2023 ·Nature Communications ·Sadiya Parveen, Jessica Shen, Shichun Lun, Liang Zhao, Jesse Alt, (unknown), Robert D. Leone, Rana Rais, Jonathan D. Powell, John R. Murphy, Barbara S. Slusher, William R. Bishai	19
5	Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug 2022 ·Science Advances ·Rana Rais, Kathryn M. Lemberg, Lukáš Tenora, Matthew L. Arwood, Arindom Pal, Jesse Alt, Ying Wu, Jenny Lam, (unknown), Liang Zhao, Diane E. Peters, Carolyn Tallon, Rajeev Pandey, Ajit G. Thomas, Ranjeet Prasad Dash, Tanguy Y. Seiwert, Pavel Majer, Robert D. Leone, Jonathan D. Powell, Barbara S. Slusher	77
6	Interrogation of T Cell–enriched Tumors Reveals Prognostic and Immunotherapeutic Implications of Polyamine Metabolism 2022 ·Cancer Research Communications ·R. Alex Harbison, Rajeev Pandey, Michael Considine, Robert D. Leone, Tracy Murray Stewart, Rossin Erbe, (unknown), Mark R. Burns, Robert A. Casero, Tanguy Y. Seiwert, Carole Fakhry, Drew M. Pardoll, Elana J. Fertig, Jonathan D. Powell	4
7	Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion breakdown → 2019 ·Science ·Robert D. Leone, Liang Zhao, Judson M. Englert, (unknown), Min Hee Oh, Im‐Hong Sun, Matthew L. Arwood, Ian A. Bettencourt, Chirag H. Patel, Jiayu Wen, Ada Tam, Richard L. Blosser, Eva Prchalová, Jesse Alt, Rana Rais, Barbara S. Slusher, Jonathan D. Powell	813
8	Targeting metabolism to regulate immune responses in autoimmunity and cancer 2019 ·Nature Reviews Drug Discovery ·Chirag H. Patel, Robert D. Leone, Maureen R. Horton, Jonathan D. Powell	196
9	Targeting adenosine for cancer immunotherapy breakdown → 2018 ·Journal for ImmunoTherapy of Cancer ·Robert D. Leone, Leisha A. Emens	417
10	Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models 2018 ·Cancer Immunology Immunotherapy ·Robert D. Leone, (unknown), Min Hee Oh, Im‐Hong Sun, Jiayu Wen, Judson M. Englert, Jonathan D. Powell	148
11	Adenosine A2A receptor antagonist, CPI-444, blocks adenosine-mediated T cell suppression and exhibits anti-tumor activity alone and in combination with anti-PD-1 and anti-PD-L1 2016 ·Annals of Oncology ·Stephen B. Willingham, Po Y. Ho, Robert D. Leone, (unknown), Jonathan D. Powell, Ian McCaffery, Richard A. Miller	2
12	Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma 2014 ·Autophagy ·Reshma Rangwala, Robert D. Leone, Yunyoung C Chang, Leslie A. Fecher, Lynn M. Schuchter, Amy Kramer, (unknown), Daniel F. Heitjan, (unknown), Maryann Gallagher, Shengfu Piao, Andrea B. Troxel, Tracey L. Evans, Angela DeMichele, Katherine L. Nathanson, Peter J. O’Dwyer, (unknown), Laura Pontiggia, Lisa E. Davis, Ravi K. Amaravadi	294
13	Autophagy: a targetable linchpin of cancer cell metabolism 2013 ·Trends in Endocrinology and Metabolism ·Robert D. Leone, Ravi K. Amaravadi	50
14	Encapsulation of crystalline topotecan in sphingosomes: a formulation suitable for clinical development 2005 ·Cancer Research ·Barbara L. Mui, (unknown), Robert D. Leone, Kim F. Wong, Kieu Lam, (unknown), Qiang Hu, Michael J. Hope	1
15	Liposome-encapsulated vincristine, vinblastine and vinorelbine: A comparative study of drug loading and retention 2005 ·Journal of Controlled Release ·Igor V. Zhigaltsev, Norbert Maurer, (unknown), Robert D. Leone, (unknown), Jinfang Wang, Sean C. Semple, Pieter R. Cullis	156
16	Optimization and Characterization of a Sphingomyelin/Cholesterol Liposome Formulation of Vinorelbine with Promising Antitumor Activity 2005 ·Journal of Pharmaceutical Sciences ·Sean C. Semple, Robert D. Leone, Jinfang Wang, (unknown), Sandra K. Klimuk, (unknown), (unknown), Katarina Edwards, Norbert Maurer, Michael J. Hope, Pieter R. Cullis, (unknown)	86
17	605 Encapsulation of vinorelbine in sphingomyelin/cholesterol liposomes enhances the tumor exposure and antitumor activity of vinorelbine in human mammary and non-small cell lung cancer solid tumor models 2004 ·European Journal of Cancer Supplements ·Sean C. Semple, (unknown), Zheng Yuan, Marianne Eisenhardt, Robert D. Leone, Heather Sweet, Preet Dhaliwal, Rostam Namdari, (unknown), Sandra K. Klimuk	1
18	Are aspen sterols and steryl esters changed structurally by kraft pulping and bleaching 1999 ·TAPPI Journal ·Junpeng Peng, Robert D. Leone, (unknown), Colette Breuil	12
19	Why fungal growth is less effective in aspen heartwood than in aspen sapwood 1997 ·Digital Commons - USU (Utah State University) ·(unknown), Robert D. Leone, Colette Breuil	3
20	Cisplatin Pharmacokinetics in Elderly Patients 1994 ·Therapeutic Drug Monitoring ·Andrea Bonetti, (unknown), P Apostoli, Gian Luigi Cetto, (unknown), A. Molino, Robert D. Leone	22

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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