Ajit G. Thomas

6.8k total citations · 1 hit paper
84 papers, 5.0k citations indexed

About

Ajit G. Thomas is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Neurology. According to data from OpenAlex, Ajit G. Thomas has authored 84 papers receiving a total of 5.0k indexed citations (citations by other indexed papers that have themselves been cited), including 51 papers in Molecular Biology, 29 papers in Cellular and Molecular Neuroscience and 15 papers in Neurology. Recurrent topics in Ajit G. Thomas's work include Neuroscience and Neuropharmacology Research (17 papers), Neuroinflammation and Neurodegeneration Mechanisms (14 papers) and Neuropeptides and Animal Physiology (14 papers). Ajit G. Thomas is often cited by papers focused on Neuroscience and Neuropharmacology Research (17 papers), Neuroinflammation and Neurodegeneration Mechanisms (14 papers) and Neuropeptides and Animal Physiology (14 papers). Ajit G. Thomas collaborates with scholars based in United States, Czechia and Japan. Ajit G. Thomas's co-authors include Barbara S. Slusher, Camilo Rojas, Brent R. Stockwell, Miki Hayano, Eric D. Lee, Caroline E. Gleason, Matthew Welsch, Nicholas P. Tatonetti, Rachid Skouta and Scott J. Dixon and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Medicine and PLoS ONE.

In The Last Decade

Ajit G. Thomas

82 papers receiving 4.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

2014 1.6k citations Ajit G. Thomas, Barbara S. Slusher et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ajit G. Thomas United States	34	2.7k	1.7k	1.4k	706	580	84	5.0k
Camilo Rojas United States	37	1.9k 0.7×	910 0.5×	638 0.4×	636 0.9×	577 1.0×	108	4.6k
Nicolai Savaskan Germany	38	2.2k 0.8×	977 0.6×	1.1k 0.7×	730 1.0×	372 0.6×	90	4.9k
Sriram Venneti United States	35	2.8k 1.0×	1.8k 1.1×	345 0.2×	400 0.6×	470 0.8×	71	5.1k
Shan Zhu China	34	2.9k 1.1×	1.3k 0.8×	1.1k 0.8×	293 0.4×	846 1.5×	89	5.3k
Shan Zhu China	24	2.6k 1.0×	1.4k 0.8×	1.5k 1.0×	840 1.2×	520 0.9×	86	5.3k
Przemysław Sapieha Canada	43	3.0k 1.1×	627 0.4×	470 0.3×	630 0.9×	244 0.4×	96	5.8k
Peter W. Gout Canada	36	3.2k 1.2×	1.4k 0.9×	1000 0.7×	223 0.3×	1.3k 2.3×	99	5.8k
Peter R. Allegrini Switzerland	37	2.8k 1.0×	554 0.3×	446 0.3×	679 1.0×	622 1.1×	75	5.3k

Countries citing papers authored by Ajit G. Thomas

Since Specialization

Citations

This map shows the geographic impact of Ajit G. Thomas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ajit G. Thomas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ajit G. Thomas more than expected).

Fields of papers citing papers by Ajit G. Thomas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ajit G. Thomas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ajit G. Thomas. The network helps show where Ajit G. Thomas may publish in the future.

Co-authorship network of co-authors of Ajit G. Thomas

This figure shows the co-authorship network connecting the top 25 collaborators of Ajit G. Thomas. A scholar is included among the top collaborators of Ajit G. Thomas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ajit G. Thomas. Ajit G. Thomas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Li, Yannan, Ajit G. Thomas, A. Sharma, et al.. (2025). Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits. Neurotherapeutics. 22(6). e00759–e00759.

Uniyal, Ankit, Niyada Hin, Qian Xu, et al.. (2025). An orally bioavailable MrgprX1-positive allosteric modulator alleviates certain neuropathic pain–related behaviors in humanized mice. Science Translational Medicine. 17(829). eadw9446–eadw9446.

Thomas, Ajit G., Niyada Hin, Lukáš Tenora, et al.. (2023). Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold. European Journal of Medicinal Chemistry. 259. 115674–115674. 2 indexed citations

Lee, Kyungho, Elizabeth A. Thompson, Chirag H. Patel, et al.. (2023). T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade. JCI Insight. 8(12). 14 indexed citations

Tallon, Carolyn, Xiaolei Zhu, Silvia Picciolini, et al.. (2023). Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice. Pharmaceutics. 15(9). 2364–2364. 5 indexed citations

Peters, Diane E., Lukáš Tenora, Xiaolei Zhu, et al.. (2023). A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis. Science Translational Medicine. 15(708). eabn7491–eabn7491. 9 indexed citations

Zhang, Fan, Zhi Zhang, Jesse Alt, et al.. (2023). Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity and improves motor function in a rabbit model of cerebral palsy. Journal of Controlled Release. 358. 27–42. 6 indexed citations

Rais, Rana, Kathryn M. Lemberg, Lukáš Tenora, et al.. (2022). Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug. Science Advances. 8(46). eabq5925–eabq5925. 77 indexed citations

Tallon, Carolyn, Anjali Sharma, Arindom Pal, et al.. (2022). Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice. Pharmaceutics. 14(10). 2066–2066. 15 indexed citations

10.

Zhu, Xiaolei, Kristen R. Hollinger, Yiyao Huang, et al.. (2022). Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV. Neurobiology of Disease. 169. 105734–105734. 16 indexed citations

11.

Thomas, Ajit G., Jesse Alt, Niyada Hin, et al.. (2021). High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan Disease. ACS Chemical Neuroscience. 12(18). 3445–3455. 6 indexed citations

12.

Yoo, Seung-Wan, Amit Agarwal, Matthew D. Smith, et al.. (2020). Inhibition of neutral sphingomyelinase 2 promotes remyelination. Science Advances. 6(40). 30 indexed citations

13.

Lo, Ying-Chun, Chih‐Hsien Cheng, Georg J. Furtmüller, et al.. (2015). Preventing Allograft Rejection by Targeting Immune Metabolism. Cell Reports. 13(4). 760–770. 144 indexed citations

14.

Yang, Wan Seok, et al.. (2015). Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility. Bioorganic & Medicinal Chemistry Letters. 25(21). 4787–4792. 105 indexed citations

15.

Raje, Mithun, Niyada Hin, Bridget Duvall, et al.. (2013). Synthesis of kojic acid derivatives as secondary binding site probes of d-amino acid oxidase. Bioorganic & Medicinal Chemistry Letters. 23(13). 3910–3913. 20 indexed citations

16.

Seltzer, Meghan J., Bryson D. Bennett, Avadhut D. Joshi, et al.. (2010). Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1. Cancer Research. 70(22). 8981–8987. 410 indexed citations

17.

Thomas, Ajit G., Camilo Rojas, Jeanette R. Hill, M.C. Shaw, & Barbara S. Slusher. (2010). Bioanalysis of N-acetyl-aspartyl-glutamate as a marker of glutamate carboxypeptidase II inhibition. Analytical Biochemistry. 404(1). 94–96. 7 indexed citations

18.

Thomas, Ajit G., Krystyna M. Wozniak, Takashi Tsukamoto, et al.. (2006). Glutamate Carboxypeptidase II (NAALADase) Inhibition as a Novel Therapeutic Strategy. Advances in experimental medicine and biology. 576. 327–337. 23 indexed citations

19.

Rojas, Camilo, Ajit G. Thomas, Pavel Majer, et al.. (2005). Glutamate Carboxypeptidase II Inhibition as a Novel Therapeutic Target. Kluwer Academic Publishers eBooks. 524. 205–213. 4 indexed citations

20.

Stoermer, Doris, Qun Liu, Ajit G. Thomas, et al.. (2003). Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II. Bioorganic & Medicinal Chemistry Letters. 13(13). 2097–2100. 40 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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