Jesse Alt

4.3k total citations · 1 hit paper
80 papers, 3.0k citations indexed

About

Jesse Alt is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Cancer Research. According to data from OpenAlex, Jesse Alt has authored 80 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Molecular Biology, 18 papers in Cellular and Molecular Neuroscience and 15 papers in Cancer Research. Recurrent topics in Jesse Alt's work include Cancer, Hypoxia, and Metabolism (14 papers), Amino Acid Enzymes and Metabolism (10 papers) and Neuroscience and Neuropharmacology Research (10 papers). Jesse Alt is often cited by papers focused on Cancer, Hypoxia, and Metabolism (14 papers), Amino Acid Enzymes and Metabolism (10 papers) and Neuroscience and Neuropharmacology Research (10 papers). Jesse Alt collaborates with scholars based in United States, Czechia and China. Jesse Alt's co-authors include Barbara S. Slusher, Rana Rais, Camilo Rojas, Margaret M. McCarthy, Ajit G. Thomas, Marigo Stathis, Jonathan D. Powell, Eva Prchalová, Judson M. Englert and Liang Zhao and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Nature Communications.

In The Last Decade

Jesse Alt

77 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

2019 813 citations Robert D. Leone, Liang Zhao et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jesse Alt United States	26	1.2k	884	532	478	399	80	3.0k
Wei Hua China	32	1.8k 1.5×	950 1.1×	362 0.7×	215 0.4×	447 1.1×	139	3.5k
Tommaso Mello Italy	34	1.3k 1.1×	340 0.4×	270 0.5×	344 0.7×	471 1.2×	90	3.4k
Dara Ditsworth United States	19	2.0k 1.7×	781 0.9×	393 0.7×	117 0.2×	484 1.2×	21	3.2k
Camilo Rojas United States	37	1.9k 1.6×	910 1.0×	228 0.4×	830 1.7×	577 1.4×	108	4.6k
Jianxin Xie China	22	3.0k 2.5×	1.2k 1.4×	483 0.9×	692 1.4×	358 0.9×	40	4.1k
Ramandeep Rattan United States	34	2.1k 1.8×	805 0.9×	395 0.7×	309 0.6×	759 1.9×	81	3.4k
Masaya Ueno Japan	28	1.6k 1.3×	370 0.4×	356 0.7×	212 0.4×	364 0.9×	61	2.7k
María Salazar‐Roa Spain	24	1.8k 1.6×	416 0.5×	237 0.4×	469 1.0×	352 0.9×	38	3.7k
Ebbe Boedtkjer Denmark	28	1.7k 1.5×	649 0.7×	141 0.3×	237 0.5×	363 0.9×	73	2.9k
Bangyan L. Stiles United States	30	3.1k 2.7×	895 1.0×	335 0.6×	655 1.4×	871 2.2×	57	4.7k

Countries citing papers authored by Jesse Alt

Since Specialization

Citations

This map shows the geographic impact of Jesse Alt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jesse Alt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jesse Alt more than expected).

Fields of papers citing papers by Jesse Alt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jesse Alt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jesse Alt. The network helps show where Jesse Alt may publish in the future.

Co-authorship network of co-authors of Jesse Alt

This figure shows the co-authorship network connecting the top 25 collaborators of Jesse Alt. A scholar is included among the top collaborators of Jesse Alt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jesse Alt. Jesse Alt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chen, Jianan, Junhua Yang, Jiachen Chu, et al.. (2024). The SWELL1 Channel Promotes Ischemic Brain Damage by Mediating Neuronal Swelling and Glutamate Toxicity. Advanced Science. 11(36). e2401085–e2401085. 9 indexed citations

Thomas, Ajit G., Niyada Hin, Lukáš Tenora, et al.. (2023). Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold. European Journal of Medicinal Chemistry. 259. 115674–115674. 2 indexed citations

Parveen, Sadiya, Jessica Shen, Shichun Lun, et al.. (2023). Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis. Nature Communications. 14(1). 7427–7427. 19 indexed citations

Lal, Bachchu, Rana Rais, Jesse Alt, et al.. (2023). Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma. Clinical Cancer Research. 29(20). 4209–4218. 4 indexed citations

Peters, Diane E., Lukáš Tenora, Xiaolei Zhu, et al.. (2023). A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis. Science Translational Medicine. 15(708). eabn7491–eabn7491. 9 indexed citations

Zhang, Fan, Zhi Zhang, Jesse Alt, et al.. (2023). Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity and improves motor function in a rabbit model of cerebral palsy. Journal of Controlled Release. 358. 27–42. 6 indexed citations

Rais, Rana, Kathryn M. Lemberg, Lukáš Tenora, et al.. (2022). Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug. Science Advances. 8(46). eabq5925–eabq5925. 77 indexed citations

Alt, Jesse, Kathryn M. Lemberg, Arindom Pal, et al.. (2021). Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement. Current Drug Metabolism. 22(9). 735–745. 3 indexed citations

Thomas, Ajit G., Jesse Alt, Niyada Hin, et al.. (2021). High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan Disease. ACS Chemical Neuroscience. 12(18). 3445–3455. 6 indexed citations

10.

Tallon, Carolyn, Silvia Picciolini, Seung‐Wan Yoo, et al.. (2021). Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury. Biochemical Pharmacology. 194. 114796–114796. 24 indexed citations

11.

Leone, Robert D., Liang Zhao, Judson M. Englert, et al.. (2019). Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 366(6468). 1013–1021. 813 indexed citations breakdown →

12.

Lemberg, Kathryn M., Liang Zhao, Ying Wu, et al.. (2019). The Novel Glutamine Antagonist Prodrug JHU395 Has Antitumor Activity in Malignant Peripheral Nerve Sheath Tumor. Molecular Cancer Therapeutics. 19(2). 397–408. 16 indexed citations

13.

Wang, Sabrina, Brad Poore, Jesse Alt, et al.. (2019). Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine. Clinical Cancer Research. 25(19). 5925–5936. 23 indexed citations

14.

Hollinger, Kristen R., Matthew D. Smith, Leslie A. Kirby, et al.. (2019). Glutamine antagonism attenuates physical and cognitive deficits in a model of MS. Neurology Neuroimmunology & Neuroinflammation. 6(6). 17 indexed citations

15.

Fahey, Jed W., Mark E. Olson, Katherine K. Stephenson, et al.. (2018). The Diversity of Chemoprotective Glucosinolates in Moringaceae (Moringa spp.). Scientific Reports. 8(1). 7994–7994. 65 indexed citations

16.

Alt, Jesse, Marigo Stathis, Camilo Rojas, & Barbara S. Slusher. (2013). Glutamate carboxypeptidase II is not an amyloid peptide‐degrading enzyme. The FASEB Journal. 27(7). 2620–2625. 4 indexed citations

17.

Raje, Mithun, Niyada Hin, Bridget Duvall, et al.. (2013). Synthesis of kojic acid derivatives as secondary binding site probes of d-amino acid oxidase. Bioorganic & Medicinal Chemistry Letters. 23(13). 3910–3913. 20 indexed citations

18.

Rais, Rana, Randall Hoover, Krystyna M. Wozniak, et al.. (2012). Reversible Disulfide Formation of the Glutamate Carboxypeptidase II Inhibitor E2072 Results in Prolonged Systemic Exposures In Vivo. Drug Metabolism and Disposition. 40(12). 2315–2323. 7 indexed citations

19.

Alt, Jesse, Camilo Rojas, Krystyna M. Wozniak, et al.. (2011). Development of a high-throughput method for the determination of pharmacological levels of plasma d-serine. Analytical Biochemistry. 419(2). 106–109. 6 indexed citations

20.

Rojas, Camilo, Ying Li, Jie Zhang, et al.. (2010). The Antiemetic 5-HT3 Receptor Antagonist Palonosetron Inhibits Substance P-Mediated Responses In Vitro and In Vivo. Journal of Pharmacology and Experimental Therapeutics. 335(2). 362–368. 108 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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