Mark Ptashne

36.4k total citations · 15 hit papers
204 papers, 30.7k citations indexed

About

Mark Ptashne is a scholar working on Molecular Biology, Genetics and Ecology. According to data from OpenAlex, Mark Ptashne has authored 204 papers receiving a total of 30.7k indexed citations (citations by other indexed papers that have themselves been cited), including 183 papers in Molecular Biology, 72 papers in Genetics and 52 papers in Ecology. Recurrent topics in Mark Ptashne's work include RNA and protein synthesis mechanisms (78 papers), Genomics and Chromatin Dynamics (68 papers) and Bacterial Genetics and Biotechnology (61 papers). Mark Ptashne is often cited by papers focused on RNA and protein synthesis mechanisms (78 papers), Genomics and Chromatin Dynamics (68 papers) and Bacterial Genetics and Biotechnology (61 papers). Mark Ptashne collaborates with scholars based in United States, United Kingdom and Germany. Mark Ptashne's co-authors include Jun Ma, Alexander Gann, Roger Brent, Grace Gill, Ivan Sadowski, Stephen C. Harrison, Edward Giniger, Michael Carey, Barbara J Meyer and Ann Hochschild and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Mark Ptashne

202 papers receiving 29.3k citations

Hit Papers

How eukaryotic transcriptional activators work 1981 2026 1996 2011 1988 1988 1997 1987 1986 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. How eukaryotic transcriptional activators work
    1988 1.7k citations Mark Ptashne Nature profile →
  2. GAL4-VP16 is an unusually potent transcriptional activator
    1988 1.2k citations Jun Ma, Mark Ptashne et al. Nature profile →
  3. Transcriptional activation by recruitment
    1997 951 citations Mark Ptashne, Alexander Gann Nature profile →
  4. Deletion analysis of GAL4 defines two transcriptional activating segments
    1987 812 citations Jun Ma, Mark Ptashne profile →
  5. Gene regulation by proteins acting nearby and at a distance
    1986 761 citations Mark Ptashne Nature profile →
  6. Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli
    1983 725 citations Mark Ptashne et al. profile →
  7. Specific DNA binding of GAL4, a positive regulatory protein of yeast
    1985 671 citations Mark Ptashne et al. profile →
  8. A new class of yeast transcriptional activators
    1987 620 citations Jun Ma, Mark Ptashne profile →
  9. Negative effect of the transcriptional activator GAL4
    1988 600 citations Grace Gill, Mark Ptashne Nature profile →
  10. A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor
    1985 573 citations Mark Ptashne et al. profile →
  11. DNA recognition by GAL4: structure of a protein-DNA complex
    1992 560 citations Michael Carey, Mark Ptashne et al. Nature profile →
  12. A vector for expressing GAL4(1–147) fusions tn mammalian cells
    1989 534 citations Mark Ptashne et al. profile →
  13. Activators and targets
    1990 516 citations Mark Ptashne, Alexander Gann Nature profile →
  14. Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein
    1986 509 citations Liam P. Keegan, Grace Gill et al. Science profile →
  15. Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae.
    1981 500 citations Mark Ptashne et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Mark Ptashne United States 91 26.5k 9.4k 3.6k 2.8k 2.0k 204 30.7k
Walter Gilbert United States 57 27.0k 1.0× 7.6k 0.8× 3.4k 0.9× 4.0k 1.4× 2.3k 1.2× 120 34.7k
Allan M. Maxam United States 20 18.3k 0.7× 6.2k 0.7× 3.0k 0.8× 2.9k 1.0× 1.9k 0.9× 25 24.1k
F. William Studier United States 60 26.8k 1.0× 11.7k 1.2× 8.2k 2.2× 3.2k 1.1× 1.9k 0.9× 98 36.5k
Paul Berg United States 85 25.6k 1.0× 9.1k 1.0× 3.4k 0.9× 3.9k 1.4× 3.0k 1.5× 217 35.8k
Carl O. Pabo United States 61 19.4k 0.7× 5.1k 0.5× 1.9k 0.5× 1.7k 0.6× 1.1k 0.6× 89 22.1k
Hamilton O. Smith United States 54 16.2k 0.6× 5.7k 0.6× 4.0k 1.1× 2.2k 0.8× 638 0.3× 125 20.5k
Clyde A. Hutchison United States 55 15.5k 0.6× 5.1k 0.5× 3.4k 0.9× 3.1k 1.1× 768 0.4× 145 20.7k
Susan Gottesman United States 93 20.2k 0.8× 14.5k 1.5× 7.3k 2.0× 1.6k 0.6× 929 0.5× 204 26.6k
Thomas A. Kunkel United States 113 42.0k 1.6× 9.1k 1.0× 2.3k 0.6× 3.9k 1.4× 2.3k 1.2× 405 51.9k
Peter H. von Hippel United States 82 23.1k 0.9× 6.5k 0.7× 3.2k 0.9× 1.1k 0.4× 573 0.3× 250 28.3k

Countries citing papers authored by Mark Ptashne

Since Specialization
Citations

This map shows the geographic impact of Mark Ptashne's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Ptashne with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Ptashne more than expected).

Fields of papers citing papers by Mark Ptashne

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Ptashne. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Ptashne. The network helps show where Mark Ptashne may publish in the future.

Co-authorship network of co-authors of Mark Ptashne

This figure shows the co-authorship network connecting the top 25 collaborators of Mark Ptashne. A scholar is included among the top collaborators of Mark Ptashne based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark Ptashne. Mark Ptashne is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Narayan, Santosh, et al.. (2017). OCT4 and SOX2 Work as Transcriptional Activators in Reprogramming Human Fibroblasts. Cell Reports. 20(7). 1585–1596. 30 indexed citations
2.
Ptashne, Mark. (2014). Francois Jacob 1920–2013. Research in Microbiology. 165(5). 396–398. 1 indexed citations
3.
Wang, Xin, Lu Bai, Gene O. Bryant, & Mark Ptashne. (2011). Nucleosomes and the accessibility problem. Trends in Genetics. 27(12). 487–492. 28 indexed citations
4.
Floer, Monique, Gene O. Bryant, & Mark Ptashne. (2008). HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast. Proceedings of the National Academy of Sciences. 105(8). 2975–2980. 62 indexed citations
5.
Ptashne, Mark. (2007). On learning to write. Current Biology. 17(11). R394–R395. 1 indexed citations
6.
Ptashne, Mark. (2007). On the use of the word ‘epigenetic’. Current Biology. 17(7). R233–R236. 254 indexed citations
7.
Ansari, Aseem Z., et al.. (2000). An artificial transcriptional activating region with unusual properties. Proceedings of the National Academy of Sciences. 97(5). 1988–1992. 29 indexed citations
8.
Ptashne, Mark & Alexander Gann. (1998). Imposing specificity by localization: mechanism and evolvability. Current Biology. 8(24). R896–R897. 12 indexed citations
9.
Ptashne, Mark & Alexander Gann. (1998). Imposing specificity by localization: mechanism and evolvability. Current Biology. 8(22). R812–R822. 57 indexed citations
10.
Saha, Shamol, Joshua M. Brickman, Norbert Lehming, & Mark Ptashne. (1993). New eukaryotic transcriptional repressers. Nature. 363(6430). 648–652. 81 indexed citations
11.
Gann, Alexander, Howard J. Himmelfarb, & Mark Ptashne. (1992). 35 GAL11, GAL11P, and the Action of GAL4. Cold Spring Harbor Monograph Archive. 931–946. 3 indexed citations
12.
Ruden, Douglas M., et al.. (1991). Generating yeast transcriptional activators containing no yeast protein sequences. Nature. 350(6315). 250–252. 164 indexed citations
13.
Chasman, Daniel I., Janet Leatherwood, Michael Carey, Mark Ptashne, & Roger D. Kornberg. (1989). Activation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro. Molecular and Cellular Biology. 9(11). 4746–4749. 55 indexed citations
14.
Ma, Jun, et al.. (1988). Yeast activators stimulate plant gene expression. Nature. 334(6183). 631–633. 139 indexed citations
15.
Keegan, Liam P., Grace Gill, & Mark Ptashne. (1986). Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein. Science. 231(4739). 699–704. 509 indexed citations breakdown →
16.
Yocum, R. Rogers, et al.. (1984). Use of lacZ Fusions to Delimit Regulatory Elements of the Inducible Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae. Molecular and Cellular Biology. 4(10). 1985–1998. 89 indexed citations
17.
Ptashne, Mark. (1980). λ Repressor Function and Structure. Cold Spring Harbor Monograph Archive. 7. 325–343. 12 indexed citations
18.
Hopkins, Nancy & Mark Ptashne. (1971). Genetics of Virulence. Cold Spring Harbor Monograph Archive. 2. 571–574. 29 indexed citations
19.
Eisen, Harvey & Mark Ptashne. (1971). Chapter 12 Regulation of Repressor Synthesis. Cold Spring Harbor Monograph Archive. 2. 239–245. 4 indexed citations
20.
Ptashne, Mark. (1971). Chapter 11 Repressor and Its Action. Cold Spring Harbor Monograph Archive. 2. 221–237. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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