Brian A. Lanman

4.3k citations

25 papers · 506 indexed · h-index 12

Impact in

Organic Chemistry top 5%
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Synthesis and Catalytic Reactions
- Chemical synthesis and alkaloids
- Oxidative Organic Chemistry Reactions
Biotechnology top 10%
- Marine Sponges and Natural Products

Papers in ⓘ

Organic Chemistry 12
- Synthetic Organic Chemistry Methods 5
- Asymmetric Synthesis and Catalysis 5
Molecular Biology 19
- Ubiquitin and proteasome pathways 6
- Sphingolipid Metabolism and Signaling 5
- Protein Kinase Regulation and GTPase Signaling 5
- Chemical Synthesis and Analysis 3

Co-authors: Andrew G. Myers (5 shared papers)Larry E. Overman (2 shared papers)Mohammad Movassaghi (2 shared papers)Daniel W. Kung (2 shared papers)Soojin Kwon (2 shared papers)Boyu Zhong (2 shared papers)Stephan G. Zech (1 shared paper)Andrew T. Parsons (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Cancer Research (5 papers)Journal of the American Chemical Society (2 papers)Organic Letters (2 papers)ACS Medicinal Chemistry Letters (2 papers)
Partner nations: United States India Denmark

In The Last Decade

Brian A. Lanman

24 papers receiving 494 citations

Peers

Countries citing papers authored by Brian A. Lanman

Since Specialization

Citations

This map shows the geographic impact of Brian A. Lanman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian A. Lanman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian A. Lanman more than expected).

Fields of papers citing papers by Brian A. Lanman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian A. Lanman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian A. Lanman. The network helps show where Brian A. Lanman may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian A. Lanman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian A. Lanman Line = papers co-authored together Brian A. Lanman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 25 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Synthesis of highly epimerizable N-protected α-amino aldehydes of high enantiomeric excess Tetrahedron Letters ·Andrew G. Myers, Boyu Zhong, Mohammad Movassaghi, Daniel W. Kung, Brian A. Lanman, Soojin Kwon	2000	89
2	On the Structure of Palau'amine: Evidence for the Revised Relative Configuration from Chemical Synthesis Journal of the American Chemical Society ·Brian A. Lanman, Larry E. Overman, Ralph Paulini, Nicole S. White	2007	67
3	Efficient, Stereoselective Synthesis of trans-2,5-Disubstituted Morpholines Organic Letters ·Brian A. Lanman, Andrew G. Myers	2004	64
4	Addressing Atropisomerism in the Development of Sotorasib, a Covalent Inhibitor of KRAS G12C: Structural, Analytical, and Synthetic Considerations Accounts of Chemical Research ·Brian A. Lanman, Andrew T. Parsons, Stephan G. Zech	2022	53
5	A Solid-Supported, Enantioselective Synthesis Suitable for the Rapid Preparation of Large Numbers of Diverse Structural Analogues of (−)-Saframycin A Journal of the American Chemical Society ·Andrew G. Myers, Brian A. Lanman	2002	49
6	The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Huiling Wang, Victor J. Cee, Frank Chavez, Brian A. Lanman, Anthony B. Reed, Bin Wu, Nadia Guerrero, J. Russell Lipford, Christine Sastri, Jeff Winston, Kristin L. Andrews, Xin Huang, Matthew R. Lee, Christopher Mohr, Yang Xu, Yihong Zhou, Andrew S. Tasker	2014	27
7	Synthesis of C-Protected α-Amino Aldehydes of High Enantiomeric Excess from Highly Epimerizable N-Protected α-Amino Aldehydes Organic Letters ·Andrew G. Myers, Boyu Zhong, Daniel W. Kung, Mohammad Movassaghi, Brian A. Lanman, Soojin Kwon	2000	23
8	Evaluation of Strategies for the Synthesis of the Guanidine Hemiaminal Portion of Palau’amine Heterocycles ·Larry E. Overman, Brian A. Lanman	2006	22
9	Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors Bioorganic & Medicinal Chemistry Letters ·Bin Wu, Huiling Wang, Victor J. Cee, Brian A. Lanman, Thomas Nixey, Liping H. Pettus, Anthony B. Reed, Ryan P. Wurz, Nadia Guerrero, Christine Sastri, Jeff Winston, J. Russell Lipford, Matthew R. Lee, Christopher Mohr, Kristin L. Andrews, Andrew S. Tasker	2015	20
10	Optimization of a Potent, Orally Active S1P₁ Agonist Containing a Quinolinone Core ACS Medicinal Chemistry Letters ·Paul E. Harrington, Michael D. Croghan, Christopher Fotsch, Mike Frohn, Brian A. Lanman, Lewis D. Pennington, Alexander J. Pickrell, Anthony B. Reed, Kelvin Sham, Andrew S. Tasker, Heather A. Arnett, Michael Fiorino, Matthew R. Lee, Michele McElvain, Henry Morrison, Han Xu, Yang Xu, Xuxia Zhang, Min Wong, Victor J. Cee	2011	13
11	Abstract 4484: Discovery and in vitro characterization of AMG 510–a potent and selective covalent small-molecule inhibitor of KRASG12C Cancer Research ·Anne Y. Saiki, Kevin Gaida, Karen Rex, Pragathi Achanta, Tisha San Miguel, Neelima Koppada, Dhanashri Bagal, Brian A. Lanman, R. Foti, John D. McCarter, Laurie P. Volak, Jude Canon, Victor J. Cee, J. Russell Lipford	2019	13
12	4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P₁ ACS Medicinal Chemistry Letters ·Lewis D. Pennington, Kelvin Sham, Alexander J. Pickrell, Paul E. Harrington, Michael Frohn, Brian A. Lanman, Anthony B. Reed, Michael D. Croghan, Matthew R. Lee, Han Xu, Michele McElvain, Yang Xu, Xuxia Zhang, Michael Fiorino, Michelle Horner, Henry Morrison, Heather A. Arnett, Christopher Fotsch, Min Wong, Victor J. Cee	2011	12
13	Novel 5- and 6-subtituted benzothiazoles with improved physicochemical properties: Potent S1P1 agonists with in vivo lymphocyte-depleting activity Bioorganic & Medicinal Chemistry Letters ·Mike Frohn, Victor J. Cee, Brian A. Lanman, Alexander J. Pickrell, Jennifer E. Golden, Dalia Rivenzon‐Segal, Scot Middleton, Mike Fiorino, Han Xu, Michael Schrag, Yang Xu, Michele McElvain, Kristine Muller, Jerry Siu, Roland W. Bürli	2011	9
14	Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation Bioorganic & Medicinal Chemistry Letters ·Anthony B. Reed, Brian A. Lanman, Jerry Ryan Holder, Bryant H. Yang, Ji Ma, Sara C. Humphreys, Zhican Wang, Joyce Chan, Les P. Miranda, Gayathri Swaminath, John G. Allen	2020	8
15	Modeling receptor flexibility in the structure-based design of KRASG12C inhibitors Journal of Computer-Aided Molecular Design ·Kai Zhu, Li Cui, Kingsley Y Wu, Christopher Mohr, Xun Li, Brian A. Lanman	2022	8
16	Abstract 4455: Discovery of AMG 510, a first-in-human covalent inhibitor of KRASG12C for the treatment of solid tumors Cancer Research ·Brian A. Lanman, Jian Jeffrey Chen, Longbin Liu, Patrícia Luciana da Costa Lopez, Alexander J. Pickrell, Anthony B. Reed, Huiling Wang, Pragathi Achanta, Jude Canon, Daniel A. Erlanson, Raymond V. Fucini, Joon Won Jeong, Christopher Mohr, Anne Y. Saiki, Victor J. Cee, J. Russell Lipford, Karen Rex, Laurie P. Volak	2019	7
17	Abstract 3090: In vivo characterization of AMG 510 - a potent and selective KRASG12Ccovalent small molecule inhibitor in preclinical KRASG12Ccancer models Cancer Research ·Karen Rex, Anne Y. Saiki, Ji-Rong Sun, Tyler Holt, Neelima Koppada, Brian A. Lanman, Laurie P. Volak, R. Foti, Victor J. Cee, J. Russell Lipford, Jude Canon	2019	6
18	Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups Bioorganic & Medicinal Chemistry Letters ·Anthony B. Reed, Brian A. Lanman, Susana Neira, Paul E. Harrington, Kelvin Sham, Mike Frohn, Alexander J. Pickrell, Andrew S. Tasker, Anu Gore, Mike Fiorino, Andrea Itano, Michele McElvain, Scot Middleton, Henry Morrison, Han Xu, Yang Xu, Min Wong, Victor J. Cee	2011	5
19	Phosphoinositide-3-kinase inhibitors: Evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511 Bioorganic & Medicinal Chemistry Letters ·Brian A. Lanman, Anthony B. Reed, Victor J. Cee, Fang‐Tsao Hong, Liping H. Pettus, Ryan P. Wurz, Kristin L. Andrews, Jian Jiang, John D. McCarter, Erin L. Mullady, Tisha San Miguel, Raju Subramanian, Ling Wang, Douglas A. Whittington, Tian Wu, Leeanne Zalameda, Nancy Zhang, Andrew S. Tasker, Paul E. Hughes, Mark H. Norman	2014	3
20	Abstract 1285: In vitro characterization of sotorasib and other RAS ‘His95-groove' binders and investigation of resistance mechanisms Cancer Research ·Anne Y. Saiki, Deanna Mohn, Yu Li, Tao Osgood, Karen Rex, Huiling Wang, Ivonne Archibeque, Christopher Mohr, Pragathi Achanta, Andres Plata Stapper, Aaron S. Rapaport, Jude Canon, Victor J. Cee, Brian A. Lanman, J. Russell Lipford	2021	3

About Brian A. Lanman

Brian A. Lanman is a scholar working on Organic Chemistry, Molecular Biology, Oncology, Biotechnology and Cancer Research, having authored 25 papers that have together received 506 indexed citations. Recurring topics across this work include Ubiquitin and proteasome pathways (6 papers), Synthetic Organic Chemistry Methods (5 papers), Sphingolipid Metabolism and Signaling (5 papers), Protein Kinase Regulation and GTPase Signaling (5 papers), Asymmetric Synthesis and Catalysis (5 papers), Colorectal Cancer Treatments and Studies (3 papers), Cancer Treatment and Pharmacology (3 papers) and Chemical Synthesis and Analysis (3 papers). The work is most often cited by research in Organic Chemistry (367 citations), Biotechnology (59 citations), Pharmacology (55 citations), Molecular Biology (221 citations) and Pharmacology (22 citations). Brian A. Lanman has collaborated with scholars based in United States, India and Denmark. Frequent co-authors include Andrew G. Myers, Larry E. Overman, Mohammad Movassaghi, Daniel W. Kung, Soojin Kwon, Boyu Zhong, Stephan G. Zech, Andrew T. Parsons, Ralph Paulini and Victor J. Cee. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Cancer Research, Journal of the American Chemical Society, Organic Letters and ACS Medicinal Chemistry Letters.

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