Piero Crespo

8.6k total citations · 4 hit papers
97 papers, 7.2k citations indexed

About

Piero Crespo is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Piero Crespo has authored 97 papers receiving a total of 7.2k indexed citations (citations by other indexed papers that have themselves been cited), including 84 papers in Molecular Biology, 23 papers in Cell Biology and 13 papers in Oncology. Recurrent topics in Piero Crespo's work include Protein Kinase Regulation and GTPase Signaling (55 papers), Melanoma and MAPK Pathways (36 papers) and Receptor Mechanisms and Signaling (14 papers). Piero Crespo is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (55 papers), Melanoma and MAPK Pathways (36 papers) and Receptor Mechanisms and Signaling (14 papers). Piero Crespo collaborates with scholars based in Spain, United States and United Kingdom. Piero Crespo's co-authors include J. Silvio Gutkind, Ningzhi Xu, Hidemi Teramoto, Omar A. Coso, Xosé R. Bustelo, M Chiariello, Jin‐Chen Yu, Toru Miki, William F. Simonds and Berta Casar and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Piero Crespo

97 papers receiving 7.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 1.5k citations Omar A. Coso, M Chiariello et al. Cell profile →
Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits

1994 720 citations Piero Crespo, Ningzhi Xu et al. profile →
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1997 679 citations Piero Crespo, J. Silvio Gutkind et al. profile →
Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase γ

1997 601 citations Piero Crespo, J. Silvio Gutkind et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Piero Crespo Spain	38	5.6k	1.4k	1.3k	987	736	97	7.2k
Tuula Kallunki Denmark	31	4.3k 0.8×	1000 0.7×	1.2k 1.0×	1.1k 1.1×	615 0.8×	52	6.3k
Kent L. Rossman United States	37	6.9k 1.2×	2.8k 2.0×	1.5k 1.2×	693 0.7×	920 1.3×	51	8.8k
Tomohiko Maehama Japan	32	6.2k 1.1×	1.5k 1.0×	1.1k 0.9×	937 0.9×	431 0.6×	66	7.6k
Tung O. Chan United States	31	4.7k 0.8×	713 0.5×	1.2k 1.0×	985 1.0×	467 0.6×	51	6.6k
Shubha Bagrodia United States	27	5.5k 1.0×	2.3k 1.6×	1.3k 1.0×	753 0.8×	406 0.6×	39	7.4k
Shigeyuki Nada Japan	34	4.7k 0.8×	1.5k 1.1×	853 0.7×	1.2k 1.2×	407 0.6×	71	6.8k
Rosana Kapeller United States	26	4.1k 0.7×	1.0k 0.7×	1.1k 0.9×	1.0k 1.0×	288 0.4×	41	5.9k
Jane McGlade Canada	23	5.0k 0.9×	1.1k 0.8×	1.4k 1.1×	1.2k 1.2×	723 1.0×	26	6.6k
Benoit Dérijard France	10	5.2k 0.9×	825 0.6×	1.5k 1.2×	1.2k 1.2×	546 0.7×	11	6.8k
Stuart J. Decker United States	37	5.3k 1.0×	867 0.6×	2.1k 1.7×	1.1k 1.1×	963 1.3×	67	7.8k

Countries citing papers authored by Piero Crespo

Since Specialization

Citations

This map shows the geographic impact of Piero Crespo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Piero Crespo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Piero Crespo more than expected).

Fields of papers citing papers by Piero Crespo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Piero Crespo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Piero Crespo. The network helps show where Piero Crespo may publish in the future.

Co-authorship network of co-authors of Piero Crespo

This figure shows the co-authorship network connecting the top 25 collaborators of Piero Crespo. A scholar is included among the top collaborators of Piero Crespo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Piero Crespo. Piero Crespo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Conde, Javier, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, et al.. (2024). The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis. Molecular Oncology. 19(1). 56–80. 4 indexed citations

Rodríguez, Javier, Alex von Kriegsheim, Michael Grusch, et al.. (2024). ERK 1/2 mitogen‐activated protein kinase dimerization is essential for the regulation of cell motility. Molecular Oncology. 19(2). 452–473. 5 indexed citations

Moreno-Rodriguez, Thaidy, Laura González-Silva, Carlos Revilla, et al.. (2021). ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer. Oncogene. 40(16). 2923–2935. 24 indexed citations

Shackleton, Sue, et al.. (2020). RAC1 induces nuclear alterations through the LINC complex to enhance melanoma invasiveness. Molecular Biology of the Cell. 31(25). 2768–2778. 11 indexed citations

Ferrer‐Mayorga, Gemma, María Jesús Larriba, Piero Crespo, & Alberto Múñoz. (2018). Mechanisms of action of vitamin D in colon cancer. The Journal of Steroid Biochemistry and Molecular Biology. 185. 1–6. 102 indexed citations

Domı́nguez, Carmen, Sales Ibiza, Natalia J. Martinez, et al.. (2016). PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death and Disease. 7(7). e2311–e2311. 8 indexed citations

Fuentes‐Calvo, Isabel, Piero Crespo, Eugenio Santos, José M. López‐Novoa, & Carlos Martı́nez-Salgado. (2013). The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833(12). 2734–2744. 16 indexed citations

Casar, Berta, Imanol Arozarena, Victoria Sanz‐Moreno, et al.. (2008). Ras Subcellular Localization Defines Extracellular Signal-Regulated Kinase 1 and 2 Substrate Specificity through Distinct Utilization of Scaffold Proteins. Molecular and Cellular Biology. 29(5). 1338–1353. 98 indexed citations

Martínez, Susana E., Francisco Lázaro‐Diéguez, Javier Selva, et al.. (2007). Lysophosphatidic acid rescues RhoA activation and phosphoinositides levels in astrocytes exposed to ethanol. Journal of Neurochemistry. 102(4). 1044–1052. 21 indexed citations

10.

Matallanas, David, Victoria Sanz‐Moreno, Imanol Arozarena, et al.. (2005). Distinct Utilization of Effectors and Biological Outcomes Resulting from Site-Specific Ras Activation: Ras Functions in Lipid Rafts and Golgi Complex Are Dispensable for Proliferation and Transformation. Molecular and Cellular Biology. 26(1). 100–116. 107 indexed citations

11.

Arozarena, Imanol, David Matallanas, Marı́a T. Berciano, et al.. (2004). Activation of H-Ras in the Endoplasmic Reticulum by the RasGRF Family Guanine Nucleotide Exchange Factors. Molecular and Cellular Biology. 24(4). 1516–1530. 83 indexed citations

12.

Vaqué, José P., Yuzuru Shiio, Marikki Laiho, et al.. (2004). Myc Antagonizes Ras-mediated Growth Arrest in Leukemia Cells through the Inhibition of the Ras-ERK-p21Cip1 Pathway. Journal of Biological Chemistry. 280(2). 1112–1122. 39 indexed citations

13.

Matallanas, David, Imanol Arozarena, Marı́a T. Berciano, et al.. (2003). Differences on the Inhibitory Specificities of H-Ras, K-Ras, and N-Ras (N17) Dominant Negative Mutants Are Related to Their Membrane Microlocalization. Journal of Biological Chemistry. 278(7). 4572–4581. 100 indexed citations

14.

Arozarena, Imanol, et al.. (2000). Distinct carboxy‐termini confer divergent characteristics to the mitogen‐activated protein kinase p38α and its splice isoform Mxi2. FEBS Letters. 474(2-3). 169–174. 25 indexed citations

15.

Gutkind, J. Silvio, Piero Crespo, Ningzhi Xu, Hidemi Teramoto, & Omar A. Coso. (1997). The pathway connecting m2 receptors to the nucleus involves small GTP-binding proteins acting on divergent map kinase cascades. Life Sciences. 60(13-14). 999–1006. 17 indexed citations

16.

Crespo, Piero, Teresa G. Cachero, Ningzhi Xu, & J. Silvio Gutkind. (1995). Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase. Journal of Biological Chemistry. 270(42). 25259–25265. 204 indexed citations

17.

Crespo, Piero, Harald Mischak, & J. Silvio Gutkind. (1995). Overexpression of Mammalian Protein Kinase C-ζ Does Not Affect the Growth Characteristics of NIH 3T3 Cells. Biochemical and Biophysical Research Communications. 213(1). 266–272. 23 indexed citations

18.

Coso, Omar A., M Chiariello, Jin‐Chen Yu, et al.. (1995). The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway. Cell. 81(7). 1137–1146. 1508 indexed citations breakdown →

19.

Berciano, Marı́a T., Piero Crespo, Carmen Rodríguez, et al.. (1995). Expression of apolipoprotein e in cholesterol-loaded macrophages of extrahepatic tissues during experimental hypercholesterolemia. Life Sciences. 56(22). 1865–1875. 4 indexed citations

20.

Lafarga, Miguel, Piero Crespo, Marı́a T. Berciano, M.A. Andrés, & Javier León. (1994). Apolipoprotein E expression in the cerebellum of normal and hypercholesterolemic rabbits. Molecular Brain Research. 21(1-2). 115–123. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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