Philip Newsholme

22.3k citations

241 papers · 15.7k indexed · 4 hit papers · h-index 66

Molecular Biology top 1%
Physiology top 0.2%
Surgery top 0.5%
Nutrition and Dietetics top 0.1%
Endocrinology, Diabetes and Metabolism top 0.5%

Co-authors: Rui Curi Vínicius Fernandes Cruzat Kevin N. Keane Eric A. Newsholme Rodrigo Carlessi Paulo Ivo Homem de Bittencourt Tânia Cristina Pithon‐Curi Colin Murphy
Topics: Pancreatic function and diabetes (62 papers)Adipose Tissue and Metabolism (46 papers)Diabetes and associated disorders (28 papers)
Cited by: Physiology Nutrition and Dietetics Biochemistry
Journals: Journal of Biological Chemistry Physiological Reviews The Journal of Immunology
Partner nations: Australia Ireland Brazil

In The Last Decade

Philip Newsholme

238 papers receiving 15.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

2018 811 citations Vínicius Fernandes Cruzat, Kevin N. Keane et al. Nutrients profile →
Molecular mechanisms of ROS production and oxidative stress in diabetes

2016 675 citations Philip Newsholme, Vínicius Fernandes Cruzat et al. profile →
Diabetes associated cell stress and dysfunction: role of mitochondrial and non‐mitochondrial ROS production and activity

2007 543 citations Philip Newsholme, Rui Curi et al. profile →
Glutamine and glutamate—their central role in cell metabolism and function

2002 523 citations Philip Newsholme, Rui Curi et al. profile →

Peers

Countries citing papers authored by Philip Newsholme

Since Specialization

Citations

This map shows the geographic impact of Philip Newsholme's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip Newsholme with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip Newsholme more than expected).

Fields of papers citing papers by Philip Newsholme

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip Newsholme. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip Newsholme. The network helps show where Philip Newsholme may publish in the future.

Co-authorship network of co-authors of Philip Newsholme

This figure shows the co-authorship network connecting the top 25 collaborators of Philip Newsholme. A scholar is included among the top collaborators of Philip Newsholme based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philip Newsholme. Philip Newsholme is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Immunometabolic Roles of Various Fatty Acids in Macrophages and Lymphocytes 2021 ·International Journal of Molecular Sciences ·José Cesar Rosa Neto,Philip C. Calder,Rui Curi,Philip Newsholme,Jaswinder K. Sethi,Loreana Sanches Silveira	34
2	Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy 2021 ·Journal of Clinical Medicine ·Ahlima Roumane,George D. Mcilroy,(unknown),Weiping Han,Mirela Delibegović,Massimiliano Baldassarre,Philip Newsholme,Justin J. Rochford	5
3	Vitamin D Supplementation Does Not Impact Resting Metabolic Rate, Body Composition and Strength in Vitamin D Sufficient Physically Active Adults 2020 ·Nutrients ·(unknown),Vínicius Fernandes Cruzat,(unknown),Angela Jacques,Philip Newsholme,Kagan J. Ducker	8
4	Use of virus-like particles as a native membrane model to study the interaction of insulin with the insulin receptor 2019 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·(unknown),Erik Helmerhorst,(unknown),(unknown),Kylie Munyard,Philip Newsholme,Cyril Mamotte	4
5	Regulation of Cancer Stem Cell Metabolism by Secreted Frizzled-Related Protein 4 (sFRP4) 2018 ·Cancers ·Abhijeet Deshmukh,Frank Arfuso,Philip Newsholme,Arun Dharmarajan	29
6	Insulin and IGF-1 receptor autocrine loops are not required for Exendin-4 induced changes to pancreatic β-cell bioenergetic parameters and metabolism in BRIN-BD11 cells 2018 ·Peptides ·Jordan Rowlands,Vínicius Fernandes Cruzat,Rodrigo Carlessi,Philip Newsholme	8
7	GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation 2017 ·Scientific Reports ·Rodrigo Carlessi,Younan Chen,Jordan Rowlands,Vínicius Fernandes Cruzat,Kevin N. Keane,(unknown),Cyril Mamotte,Rebecca Stokes,Jenny E. Gunton,Paulo Ivo Homem de Bittencourt,Philip Newsholme	95
8	Therapeutic approach to target mesothelioma cancer cells using the Wnt antagonist, secreted frizzled-related protein 4: Metabolic state of cancer cells 2016 ·Experimental Cell Research ·(unknown),Sebastian Pohl,Kevin N. Keane,Frank Arfuso,Philip Newsholme,Simon A. Fox,Arun Dharmarajan	11
9	The Impact of Vitamin D Levels on Inflammatory Status: A Systematic Review of Immune Cell Studies 2015 ·PLoS ONE ·Emily Calton,Kevin N. Keane,Philip Newsholme,Mário J. Soares	296
10	Metabolic Regulation of Insulin Secretion 2014 ·Vitamins and hormones ·Kevin N. Keane,Philip Newsholme	33
11	Mechanisms of PEDF-mediated protection against reactive oxygen species damage in diabetic retinopathy and neuropathy 2014 ·Journal of Endocrinology ·Mina Elahy,(unknown),Vínicius Fernandes Cruzat,Philip Newsholme,Crispin R. Dass	47
12	l-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge 2011 ·Journal of Endocrinology ·Maurício Krause,Neville H. McClenaghan,Peter R. Flatt,Paulo Ivo Homem de Bittencourt,Colin Murphy,Philip Newsholme	72
13	Nutrient Regulation of Insulin Secretion and β-Cell Functional Integrity 2010 ·Advances in experimental medicine and biology ·Philip Newsholme,Céline Gaudel,Neville H. McClenaghan	63
14	In vivo and in vitro studies of GAD-antibody positive subjects with Type 2 diabetes: A distinct sub-phenotype 2008 ·Diabetes Research and Clinical Practice ·Donal J. O’Gorman,Obada Yousif,Gordon H. Dixon,Siobhán McQuaid,Elaine Murphy,(unknown),D. Gasparro,Giovanni Pacini,Philip Newsholme,John J. Nolan	3
15	Prolonged alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic beta cells 2007 ·Diabetologia ·Lorraine Brennan,(unknown),(unknown),(unknown),J. Paul G. Malthouse,Peter R. Flatt,Philip Newsholme,Neville H. McClenaghan	2
16	Amino acid metabolism, insulin secretion and diabetes 2007 ·Proceedings of The Physiological Society ·Aoife P. Kiely,(unknown),Lorraine Brennan,Philip Newsholme	1
17	Glucose metabolism in lymphoid and inflammatory cells and tissues 2007 ·Current Opinion in Clinical Nutrition & Metabolic Care ·Philip C. Calder,George Dimitriadis,Philip Newsholme	111
18	Why Is L-Glutamine Metabolism Important to Cells of the Immune System in Health, Postinjury, Surgery or Infection? 2001 ·Journal of Nutrition ·Philip Newsholme	478
19	Influence of cell culture conditions on diet-induced changes in lymphocyte fatty acid composition 1995 ·Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ·Parveen Yaqoob,Philip Newsholme,Philip C. Calder	66
20	Motifs of protein phosphorylation and mechanisms of reversible covalent regulation 1991 ·Physiological Reviews ·Donal A. Walsh,Philip Newsholme,(unknown),Scott M. Van Patten,(unknown)	19

About Philip Newsholme

Philip Newsholme is a scholar working on Physiology, Biochemistry and Nutrition and Dietetics, having authored 241 papers that have together received 15.7k indexed citations. Recurring topics across this work include Pancreatic function and diabetes (62 papers), Adipose Tissue and Metabolism (46 papers) and Diabetes and associated disorders (28 papers). The work is most often cited by research in Physiology (4.6k citations), Nutrition and Dietetics (2.4k citations) and Biochemistry (986 citations). Philip Newsholme has collaborated with scholars based in Australia, Ireland and Brazil. Frequent co-authors include Rui Curi, Vínicius Fernandes Cruzat, Kevin N. Keane, Eric A. Newsholme, Rodrigo Carlessi, Paulo Ivo Homem de Bittencourt, Tânia Cristina Pithon‐Curi, Colin Murphy, Maurício Krause and Philip C. Calder. Their work appears in journals such as Journal of Biological Chemistry, Physiological Reviews and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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