Paula Kaplan‐Lefko

2.5k citations

26 papers · 1.3k indexed · h-index 13

Hepatology top 5%
- Liver physiology and pathology 7
Oncology top 5%
- CAR-T cell therapy research 7
- Pancreatic and Hepatic Oncology Research 3
Immunology top 10%
- Immunotherapy and Immune Responses 6
Cancer Research top 10%
- Cancer, Hypoxia, and Metabolism 6
Pulmonary and Respiratory Medicine top 10%
Genetics
- Virus-based gene therapy research 5
Endocrinology, Diabetes and Metabolism
- Growth Hormone and Insulin-like Growth Factors 4
Molecular Biology
- Cell death mechanisms and regulation 3

Co-authors: Norman M. Greenberg Barbara A. Foster Gustavo E. Ayala Wendy J. Huss Lisette A. Maddison Roberto Barrios Michael Ittmann Angela Coxon
Cited by: Hepatology Oncology Immunology
Journals: Journal of Biological Chemistry (1 paper)Journal of Clinical Oncology (1 paper)Cancer Research (6 papers)
Partner nations: United States Canada France

In The Last Decade

Paula Kaplan‐Lefko

26 papers receiving 1.3k citations

Peers

Countries citing papers authored by Paula Kaplan‐Lefko

Since Specialization

Citations

This map shows the geographic impact of Paula Kaplan‐Lefko's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paula Kaplan‐Lefko with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paula Kaplan‐Lefko more than expected).

Fields of papers citing papers by Paula Kaplan‐Lefko

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paula Kaplan‐Lefko. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paula Kaplan‐Lefko. The network helps show where Paula Kaplan‐Lefko may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Paula Kaplan‐Lefko, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paula Kaplan‐Lefko Line = papers co-authored together Paula Kaplan‐Lefko links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Immunotherapy resistance driven by loss of NY-ESO-1 expression in response to transgenic adoptive cellular therapy with PD-1 blockade Journal for ImmunoTherapy of Cancer ·Luke Frankiw,Arun S. Singh,Cole W. Peters,Begoña Comı́n-Anduix,Beata Berent-Maoz,Mignonette H. Macabali,Kiana Shammaie,Crystal Quiros,Paula Kaplan‐Lefko,Ignacio Baselga-Carretero,Antoni Ribas,Theodore S. Nowicki	2023	11
2	Infusion Product TNFα, Th2, and STAT3 Activities Are Associated with Clinical Responses to Transgenic T-cell Receptor Cell Therapy Cancer Immunology Research ·Theodore S. Nowicki,Cole W. Peters,Crystal Quiros,Conner K. Kidd,Moe Kawakami,Alexandra M. Klomhaus,Ignacio Baselga-Carretero,Paula Kaplan‐Lefko,Mignonette H. Macabali,Ivan Perez Garcilazo,Beata Berent-Maoz,Begoña Comı́n-Anduix,Antoni Ribas	2023	2
3	Abstract CT008: A pilot trial of the combination of transgenic NY-ESO-1-reactive adoptive cellular therapy with dendritic cell vaccination with or without ipilimumab in patients with sarcoma and melanoma Cancer Research ·Theodore S. Nowicki,Beata Berent-Maoz,Rong Huang,Xiaoyan Wang,Gardenia Cheung-Lau,Paula Kaplan‐Lefko,Paula Cabrera,Justin Tran,Ignacio Baselga-Carretero,Catherine S. Grasso,Siwen Hu‐Lieskovan,Bartosz Chmielowski,Begoña Comı́n-Anduix,Arun S. Singh,Antoni Ribas	2018	2
4	A phase I, open-label, dose-escalation and cohort expansion study evaluating the safety and immune response to autologous dendritic cells transduced with AdGMCA9 in patients with metastatic renal cell carcinoma. Journal of Clinical Oncology ·Izak Faiena,Nazy Zomorodian,Begonya Comin-Anduix,Ankush Sachadeva,Adrian Bot,Fariouz Kabinnivar,Jonathan Said,Gardenia Cheung-Lau,Jia Pang,Mignonette H. Macabali,Paula Cabrera,Paula Kaplan‐Lefko,Beata Berent-Maoz,Sandy Liu,Allan J. Pantuck,Arie S. Belldegrun,Karim Chamie,Alexandra Drakaki	2018	1
5	In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models Molecular Cancer Therapeutics ·Paul E. Hughes,Karen Rex,Sean Caenepeel,Yajing Yang,Yihong Zhang,Martin A. Broome,Hue T. Kha,Teresa L. Burgess,Benny Amore,Paula Kaplan‐Lefko,Jodi Moriguchi,Jonathan Werner,Michael A. Damore,D. N. Baker,Deborah M. Choquette,Jean-Christophe Harmange,Robert Radinsky,Richard Kendall,Isabelle Dussault,Angela Coxon	2016	44
6	PD-1 Blockade Expands Intratumoral Memory T Cells Cancer Immunology Research ·Antoni Ribas,Daniel Sanghoon Shin,Jesse M. Zaretsky,Juliet Frederiksen,Andrew Cornish,Earl Avramis,Elizabeth Seja,Christine Kivork,Janet Siebert,Paula Kaplan‐Lefko,Xiaoyan Wang,Bartosz Chmielowski,John A. Glaspy,Paul C. Tumeh,Thinle Chodon,Dana Pe’er,Begoña Comı́n-Anduix	2016	302
7	Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method Laboratory Investigation ·Marc Payton,Toni Jun,William C. Wayne,Dongyin Yu,Raffi Manoukian,Grace Chung,Nancy R. Zhang,Ji-Rong Sun,Paula Kaplan‐Lefko,Sheila Scully,Gwyneth Van,Robert Radinsky,Richard Kendall,Jonathan D. Oliner,Angela Coxon	2014	5
8	Characterization of ⁶⁴Cu-DOTA-Conatumumab: A PET Tracer for In Vivo Imaging of Death Receptor 5 Journal of Nuclear Medicine ·Raffaella Rossin,Tadahiko Kohno,Aviv Hagooly,Terry L. Sharp,Brian Gliniak,Thomas Arroll,Qing Chen,Art Hewig,Paula Kaplan‐Lefko,Greg Friberg,Robert Radinsky,Jeffrey L. Evelhoch,Michael J. Welch,Dah‐Ren Hwang	2011	12
9	Safety, Pharmacokinetics, and Pharmacodynamics of AMG 102, a Fully Human Hepatocyte Growth Factor–Neutralizing Monoclonal Antibody, in a First-in-Human Study of Patients with Advanced Solid Tumors Clinical Cancer Research ·Michael S. Gordon,Christopher J. Sweeney,David S. Mendelson,S. Gail Eckhardt,Abraham Anderson,Darrin M. Beaupre,Daniel Branstetter,Teresa L. Burgess,Angela Coxon,Hongjie Deng,Paula Kaplan‐Lefko,Ian M. Leitch,Kelly S. Oliner,Lucy Yan,Min Zhu,Lia Gore	2010	133
10	Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types Cancer Biology & Therapy ·Paula Kaplan‐Lefko,Jonathan D. Graves,Stephen J. Zoog,Yang Pan,Jason Wall,Daniel Branstetter,Jodi Moriguchi,Angela Coxon,Justin Huard,Ren Xu,Matthew Peach,Gloria Juan,Stephen A. Kaufman,Qing Chen,Allison Bianchi,Jennifer J. Kordich,Mark Ma,Ian N. Foltz,Brian Gliniak	2010	100
11	Measurement of conatumumab‐induced apoptotic activity in tumors by fine needle aspirate sampling Cytometry Part A ·Stephen J. Zoog,Y. Connie,Paula Kaplan‐Lefko,Jennifer M. Hawkins,Jodi Moriguchi,Lei Zhou,Yang Pan,Cheng‐Pang Hsu,Greg Friberg,Roy S. Herbst,John S. Hill,Gloria Juan	2010	14
12	Conditional Deletion of Insulin-like Growth Factor-I Receptor in Prostate Epithelium Cancer Research ·Brent W. Sutherland,Sue E. Knoblaugh,Paula Kaplan‐Lefko,Fen Wang,Martin Holzenberger,Norman M. Greenberg	2008	54
13	Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity In vivo Cancer Research ·Yihong Zhang,Paula Kaplan‐Lefko,Karen Rex,Yajing Yang,Jodi Moriguchi,Tao Osgood,Bethany Mattson,Angela Coxon,Monica Reese,Tae‐Seong Kim,Jasmine Lin,April Chen,Teresa L. Burgess,Isabelle Dussault	2008	47
14	AMG 655, a fully human agonistic antibody against TRAIL receptor-2, induces apoptosis via caspase activation in vitro and in vivo Cancer Research ·Paula Kaplan‐Lefko,Yongmei Gan,Justin Huard,Matt Colloton,Steve Zoog,Gloria Juan,Taska Dobson,Matt Peach,Yang Pan,Steve Kaufman,Dan Branstetter,Angela Coxon,Allison Bianchi,Sharon Wong-Madden,Ian N. Foltz,Brian Gliniak	2007	3
15	Identification and characterization of a novel RON/c-Met small molecule inhibitor Molecular Cancer Therapeutics ·Yihong Zhang,Paula Kaplan‐Lefko,Karen Rex,Yajing Yang,Jodi Moriguchi,Tao Osgood,Bethany Mattson,Angela Coxon,Teresa L. Burgess,Isabelle Dussault	2007	2
16	c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations Journal of Biological Chemistry ·Steven F. Bellon,Paula Kaplan‐Lefko,Yajing Yang,Yihong Zhang,Jodi Moriguchi,Karen Rex,Carol W. Johnson,Paul Rose,Alexander Long,Anne O’Connor,Yan Gu,Angela Coxon,Tae‐Seong Kim,Andrew S. Tasker,Teresa L. Burgess,Isabelle Dussault	2007	113
17	Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis Oncogene ·Paula Kaplan‐Lefko,Brent W. Sutherland,Andreas Evangelou,Darryl L. Hadsell,R Barrios,Barbara A. Foster,Francesco J. DeMayo,Norman M. Greenberg	2007	26
18	Identification of genes potentially involved in the acquisition of androgen‐independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model The Prostate ·Sharon D. Morgenbesser,Rajashree McLaren,Brenda Richards,Mindy Zhang,Viatcheslav R. Akmaev,Scott F. Winter,Nora D. Mineva,Paula Kaplan‐Lefko,Barbara A. Foster,Brian P. Cook,Michael R. Dufault,Xiahong Cao,Clarence J. Wang,Beverly A. Teicher,K. Klinger,Norman M. Greenberg,Stephen F. Madden	2006	23
19	A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model Oncogene ·Noreen Majeed,Marie‐José Blouin,Paula Kaplan‐Lefko,Jane Barry-Shaw,Norman M. Greenberg,Pierrette Gaudreau,Tarek A. Bismar,Michaël Pollak	2005	49
20	Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model The Prostate ·Paula Kaplan‐Lefko,T C Chen,Michael Ittmann,Roberto Barrios,Gustavo E. Ayala,Wendy J. Huss,Lisette A. Maddison,Barbara A. Foster,Norman M. Greenberg	2003	359

About Paula Kaplan‐Lefko

Paula Kaplan‐Lefko is a scholar working on Hepatology, Immunology and Cancer Research, having authored 26 papers that have together received 1.3k indexed citations. Recurring topics across this work include CAR-T cell therapy research (7 papers), Liver physiology and pathology (7 papers), Cancer, Hypoxia, and Metabolism (6 papers), Immunotherapy and Immune Responses (6 papers), Virus-based gene therapy research (5 papers), Growth Hormone and Insulin-like Growth Factors (4 papers), Pancreatic and Hepatic Oncology Research (3 papers) and Cell death mechanisms and regulation (3 papers). The work is most often cited by research in Hepatology (202 citations), Oncology (557 citations) and Immunology (348 citations). Paula Kaplan‐Lefko has collaborated with scholars based in United States, Canada and France. Frequent co-authors include Norman M. Greenberg, Barbara A. Foster, Gustavo E. Ayala, Wendy J. Huss, Lisette A. Maddison, Roberto Barrios, Michael Ittmann, Angela Coxon, Teresa L. Burgess and Begoña Comı́n-Anduix. Their work appears in journals such as Journal of Biological Chemistry, Journal of Clinical Oncology and Cancer Research.

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