Patrick S. Mitchell

15.2k citations

35 papers · 12.3k indexed · 3 hit papers · h-index 21

Impact in

Cancer Research top 0.05%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Molecular Biology top 0.2%
- Circular RNAs in diseases
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- RNA modifications and cancer
- Advanced biosensing and bioanalysis techniques
- Inflammasome and immune disorders

Papers in ⓘ

Virology 4
- HIV Research and Treatment 4
Cancer Research 10
- MicroRNA in disease regulation 10
- Cancer-related molecular mechanisms research 6

Co-authors: Muneesh Tewari (11 shared papers)Evan M. Kroh (6 shared papers)Rachael K. Parkin (5 shared papers)Era L. Pogosova‐Agadjanyan (2 shared papers)Derek L. Stirewalt (2 shared papers)Brian R. Fritz (4 shared papers)Stacia K. Wyman (3 shared papers)Beatrice S. Knudsen (3 shared papers)
Journals: eLife (4 papers)Proceedings of the National Academy of Sciences (4 papers)Molecular Cancer Research (2 papers)PLoS Pathogens (2 papers)PLoS ONE (2 papers)
Partner nations: United States South Africa United Kingdom

In The Last Decade

Patrick S. Mitchell

33 papers receiving 12.2k citations

Hit Papers

align trajectories log scale

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma 2011 · 2.7k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Proceedings of the National Academy of Sciences
2010 Methods
2008 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Patrick S. Mitchell

Since Specialization

Citations

This map shows the geographic impact of Patrick S. Mitchell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick S. Mitchell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick S. Mitchell more than expected).

Fields of papers citing papers by Patrick S. Mitchell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick S. Mitchell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick S. Mitchell. The network helps show where Patrick S. Mitchell may publish in the future.

Co-authors

The 25 scholars most cited alongside Patrick S. Mitchell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick S. Mitchell Line = papers co-authored together Patrick S. Mitchell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 35 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Circulating microRNAs as stable blood-based markers for cancer detection Proceedings of the National Academy of Sciences ·Patrick S. Mitchell, Rachael K. Parkin, Evan M. Kroh, Brian R. Fritz, Stacia K. Wyman, Era L. Pogosova‐Agadjanyan, Amelia C. Peterson, Jennifer Noteboom, Kathy O'Briant, April N. Allen, Daniel W. Lin, Nicole Urban, Charles W. Drescher, Beatrice S. Knudsen, Derek L. Stirewalt, Robert Gentleman, Robert L. Vessella, Peter S. Nelson, Daniel Martin, Muneesh Tewari Hit paper breakdown →	2008	6512
2	Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma Proceedings of the National Academy of Sciences ·Jason D. Arroyo, John R. Chevillet, Evan M. Kroh, Ingrid K. Ruf, Colin C. Pritchard, Donald Gibson, Patrick S. Mitchell, Christopher F. Bennett, Era L. Pogosova‐Agadjanyan, Derek L. Stirewalt, Jonathan F. Tait, Muneesh Tewari Hit paper breakdown →	2011	2675
3	Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR) Methods ·Evan M. Kroh, Rachael K. Parkin, Patrick S. Mitchell, Muneesh Tewari Hit paper breakdown →	2010	989
4	Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes Science ·Andrew Sandstrom, Patrick S. Mitchell, Lisa Goers, Edward Mu, Cammie F. Lesser, Russell E. Vance	2019	271
5	MicroRNA Discovery and Profiling in Human Embryonic Stem Cells by Deep Sequencing of Small RNA Libraries Stem Cells ·Merav Bar, Stacia K. Wyman, Brian R. Fritz, Junlin Qi, Kavita S. Garg, Rachael K. Parkin, Evan M. Kroh, Ausra Bendoraite, Patrick S. Mitchell, Angelique M. Nelson, Walter L. Ruzzo, Carol B. Ware, Jerald P. Radich, Robert Gentleman, Hannele Ruohola‐Baker, Muneesh Tewari	2008	247
6	Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer Oncogene ·William M. Grady, Rachael K. Parkin, Patrick S. Mitchell, J. H. Lee, Y-H Kim, Karen D. Tsuchiya, M. Kay Washington, Christos Paraskeva, James K. V. Willson, Andrew M. Kaz, Evan M. Kroh, April N. Allen, Brian R. Fritz, Sanford D. Markowitz, Muneesh Tewari	2008	233
7	Repertoire of microRNAs in Epithelial Ovarian Cancer as Determined by Next Generation Sequencing of Small RNA cDNA Libraries PLoS ONE ·Stacia K. Wyman, Rachael K. Parkin, Patrick S. Mitchell, Brian R. Fritz, Kathy O'Briant, Andrew K. Godwin, Nicole Urban, Charles W. Drescher, Beatrice S. Knudsen, Muneesh Tewari	2009	193
8	Circulating microRNA Profiling Identifies a Subset of Metastatic Prostate Cancer Patients with Evidence of Cancer-Associated Hypoxia PLoS ONE ·Heather H. Cheng, Patrick S. Mitchell, Evan M. Kroh, Alexander E. Dowell, Lisly Chéry, Javed Siddiqui, Peter S. Nelson, Robert L. Vessella, Beatrice S. Knudsen, Arul M. Chinnaiyan, Kenneth J. Pienta, Colm Morrissey, Muneesh Tewari	2013	153
9	The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries Current Opinion in Immunology ·Patrick S. Mitchell, Andrew Sandstrom, Russell E. Vance	2019	138
10	MicroRNA-138 Modulates DNA Damage Response by Repressing Histone H2AX Expression Molecular Cancer Research ·Yemin Wang, Jen‐Wei Huang, Ming Li, Webster K. Cavenee, Patrick S. Mitchell, Xiaofeng Zhou, Muneesh Tewari, Frank B. Furnari, Toshiyasu Taniguchi	2011	121
11	Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA Cell Host & Microbe ·Patrick S. Mitchell, Corinna Patzina, Michael Emerman, Otto Haller, Harmit S. Malik, Georg Kochs	2012	117
12	Multiple Integrated Copies and High-Level Production of the Human Retrovirus XMRV (Xenotropic Murine Leukemia Virus-Related Virus) from 22Rv1 Prostate Carcinoma Cells Journal of Virology ·Emily C. Knouf, Michael J. Metzger, Patrick S. Mitchell, Jason D. Arroyo, John R. Chevillet, Muneesh Tewari, A. Dusty Miller	2009	103
13	Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation PLoS Pathogens ·Joseph Chavarría‐Smith, Patrick S. Mitchell, Alvin M. Ho, Matthew D. Daugherty, Russell E. Vance	2016	94
14	Systematic Screen Identifies miRNAs That Target RAD51 and RAD51D to Enhance Chemosensitivity Molecular Cancer Research ·Jen‐Wei Huang, Yemin Wang, Kiranjit K. Dhillon, Philamer Calses, Emily Villegas, Patrick S. Mitchell, Muneesh Tewari, Christopher J. Kemp, Toshiyasu Taniguchi	2013	81
15	NAIP–NLRC4-deficient mice are susceptible to shigellosis eLife ·Patrick S. Mitchell, Justin L. Roncaioli, Elizabeth A Turcotte, Lisa Goers, Roberto A. Chavez, Angus Y. Lee, Cammie F. Lesser, Isabella Rauch, Russell E. Vance	2020	65
16	MiR‐221 and MiR‐222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B, CDKNIC and overall survival Genes Chromosomes and Cancer ·Kaitlyn Wurz, Rochelle L. Garcia, Barbara A. Goff, Patrick S. Mitchell, Jun Haeng Lee, Muneesh Tewari, Elizabeth M. Swisher	2010	65
17	Molecular characterization of a fungal gasdermin-like protein Proceedings of the National Academy of Sciences ·Asen Daskalov, Patrick S. Mitchell, Andrew Sandstrom, Russell E. Vance, N. Louise Glass	2020	57
18	An evolutionary perspective on the broad antiviral specificity of MxA Current Opinion in Microbiology ·Patrick S. Mitchell, Michael Emerman, Harmit S. Malik	2013	55
19	Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction PLoS Pathogens ·Patrick S. Mitchell, Janet M. Young, Michael Emerman, Harmit S. Malik	2015	37
20	Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome PLoS Biology ·Brian V. Tsu, Rimjhim Agarwal, Nandan S. Gokhale, Jessie Kulsuptrakul, Andrew P. Ryan, Elizabeth J. Fay, Lennice K. Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A Turcotte, Sofia E. Delgado-Rodriguez, Russell E. Vance, Jennifer Hyde, Ram Savan, Patrick S. Mitchell, Matthew D. Daugherty	2023	26

About Patrick S. Mitchell

Patrick S. Mitchell is a scholar working on Virology, Cancer Research, Immunology, Biological Psychiatry and Endocrinology, having authored 35 papers that have together received 12.3k indexed citations. Recurring topics across this work include Inflammasome and immune disorders (13 papers), MicroRNA in disease regulation (10 papers), Cancer-related molecular mechanisms research (6 papers), Circular RNAs in diseases (5 papers), HIV Research and Treatment (4 papers), Heme Oxygenase-1 and Carbon Monoxide (4 papers), Immune Cell Function and Interaction (4 papers) and interferon and immune responses (4 papers). The work is most often cited by research in Cancer Research (9.1k citations), Molecular Biology (10.1k citations), Immunology (1.1k citations), Obstetrics and Gynecology (252 citations) and Nephrology (155 citations). Patrick S. Mitchell has collaborated with scholars based in United States, South Africa and United Kingdom. Frequent co-authors include Muneesh Tewari, Evan M. Kroh, Rachael K. Parkin, Era L. Pogosova‐Agadjanyan, Derek L. Stirewalt, Brian R. Fritz, Stacia K. Wyman, Beatrice S. Knudsen, Kathy O'Briant and Nicole Urban. Their work appears in journals such as eLife, Proceedings of the National Academy of Sciences, Molecular Cancer Research, PLoS Pathogens and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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