Mercedes Tkach

21.4k total citations · 3 hit papers
25 papers, 8.3k citations indexed

About

Mercedes Tkach is a scholar working on Molecular Biology, Immunology and Cancer Research. According to data from OpenAlex, Mercedes Tkach has authored 25 papers receiving a total of 8.3k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 13 papers in Immunology and 9 papers in Cancer Research. Recurrent topics in Mercedes Tkach's work include Extracellular vesicles in disease (13 papers), MicroRNA in disease regulation (7 papers) and Immunotherapy and Immune Responses (7 papers). Mercedes Tkach is often cited by papers focused on Extracellular vesicles in disease (13 papers), MicroRNA in disease regulation (7 papers) and Immunotherapy and Immune Responses (7 papers). Mercedes Tkach collaborates with scholars based in France, Argentina and United States. Mercedes Tkach's co-authors include Clotilde Théry, Joanna Kowal, Mabel Jouve, Damarys Loew, Florent Dingli, Marina Colombo, Bjarke Primdal-Bengtson, Guillaume Arras, Lorena Martín‐Jaular and Roxana Schillaci and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Mercedes Tkach

25 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

2016 2.7k citations Mercedes Tkach, Clotilde Théry Cell profile →
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

2016 2.6k citations Joanna Kowal, Guillaume Arras et al. Proceedings of the National Academy of Sciences profile →
Biogenesis and secretion of exosomes

2014 1.4k citations Joanna Kowal, Mercedes Tkach et al. Current Opinion in Cell Biology profile →

Peers

Mercedes Tkach

IMMUN

Marina Colombo France

Cecilia Lässer Sweden

David W. Greening Australia

Jeffrey L. Franklin United States

Kenneth W. Witwer United States

Joanna Kowal Poland

Alicia Llorente Norway

Gisela D’Angelo France

Imre Mäger United Kingdom

D. Michiel Pegtel Netherlands

Marina Colombo France

Mercedes Tkach

9.3k ×1.3

4.9k ×1.3

1.6k ×1.0

IMMUN

828 ×1.1

607 ×1.1

Citations per year, relative to Mercedes Tkach Mercedes Tkach (= 1×) peers Marina Colombo

Countries citing papers authored by Mercedes Tkach

Since Specialization

Citations

This map shows the geographic impact of Mercedes Tkach's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mercedes Tkach with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mercedes Tkach more than expected).

Fields of papers citing papers by Mercedes Tkach

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mercedes Tkach. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mercedes Tkach. The network helps show where Mercedes Tkach may publish in the future.

Co-authorship network of co-authors of Mercedes Tkach

This figure shows the co-authorship network connecting the top 25 collaborators of Mercedes Tkach. A scholar is included among the top collaborators of Mercedes Tkach based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mercedes Tkach. Mercedes Tkach is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cocozza, Federico, Lorena Martín‐Jaular, Lien Lippens, et al.. (2023). Extracellular vesicles and co‐isolated endogenous retroviruses from murine cancer cells differentially affect dendritic cells. The EMBO Journal. 42(24). e113590–e113590. 21 indexed citations

Tkach, Mercedes, Cláudio Pinheiro, Ilkka Miinalainen, et al.. (2023). Depletion of soluble cytokines unlocks the immunomodulatory bioactivity of extracellular vesicles. Journal of Extracellular Vesicles. 12(8). e12339–e12339. 13 indexed citations

Tkach, Mercedes, Jessie Thalmensi, Eleonora Timperi, et al.. (2022). Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome. Proceedings of the National Academy of Sciences. 119(17). e2107394119–e2107394119. 83 indexed citations

Tkach, Mercedes, Caroline Hego, Marc Michel, et al.. (2022). Circulating extracellular vesicles provide valuable protein, but not DNA, biomarkers in metastatic breast cancer. SHILAP Revista de lepidopterología. 1(7). e51–e51. 6 indexed citations

Martín‐Jaular, Lorena, Nathalie Névo, Julia P. Schessner, et al.. (2021). Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV‐1 infection. The EMBO Journal. 40(8). e105492–e105492. 44 indexed citations

Cocozza, Federico, Nathalie Névo, Xavier Lahaye, et al.. (2020). Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus. Journal of Extracellular Vesicles. 10(2). e12050–e12050. 108 indexed citations

Kowal, Joanna & Mercedes Tkach. (2019). Dendritic cell extracellular vesicles. International review of cell and molecular biology. 349. 213–249. 55 indexed citations

Tkach, Mercedes, Joanna Kowal, Andrés E. Zucchetti, et al.. (2017). Qualitative differences in T‐cell activation by dendritic cell‐derived extracellular vesicle subtypes. The EMBO Journal. 36(20). 3012–3028. 292 indexed citations

Tkach, Mercedes, Joanna Kowal, & Clotilde Théry. (2017). Why the need and how to approach the functional diversity of extracellular vesicles. Philosophical Transactions of the Royal Society B Biological Sciences. 373(1737). 20160479–20160479. 254 indexed citations

10.

Tkach, Mercedes & Clotilde Théry. (2016). Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. Cell. 164(6). 1226–1232. 2684 indexed citations breakdown →

11.

Kowal, Joanna, Guillaume Arras, Marina Colombo, et al.. (2016). Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proceedings of the National Academy of Sciences. 113(8). E968–77. 2625 indexed citations breakdown →

12.

Russo, Rosalía I. Cordo, Wendy Béguelin, María C. Díaz Flaqué, et al.. (2014). Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance. Oncogene. 34(26). 3413–3428. 42 indexed citations

13.

Kowal, Joanna, Mercedes Tkach, & Clotilde Théry. (2014). Biogenesis and secretion of exosomes. Current Opinion in Cell Biology. 29. 116–125. 1432 indexed citations breakdown →

14.

Izzo, Franco, María F. Mercogliano, Leandro Venturutti, et al.. (2014). Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. Breast Cancer Research. 16(6). 491–491. 27 indexed citations

15.

Tkach, Mercedes, Cinthia Rosemblit, Martín A. Rivas, et al.. (2013). p42/p44 MAPK-mediated Stat3Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth. Endocrine Related Cancer. 20(2). 197–212. 77 indexed citations

16.

Tkach, Mercedes, Mariya I. Meschaninova, Martín A. Rivas, et al.. (2012). Small Interfering RNA Targeted to IGF-IR Delays Tumor Growth and Induces Proinflammatory Cytokines in a Mouse Breast Cancer Model. PLoS ONE. 7(1). e29213–e29213. 38 indexed citations

17.

Tkach, Mercedes, Lorena M. Coria, Cinthia Rosemblit, et al.. (2012). Targeting Stat3 Induces Senescence in Tumor Cells and Elicits Prophylactic and Therapeutic Immune Responses against Breast Cancer Growth Mediated by NK Cells and CD4+ T Cells. The Journal of Immunology. 189(3). 1162–1172. 43 indexed citations

18.

Béguelin, Wendy, María C. Díaz Flaqué, Cecilia J. Proietti, et al.. (2010). Progesterone Receptor Induces ErbB-2 Nuclear Translocation To Promote Breast Cancer Growth via a Novel Transcriptional Effect: ErbB-2 Function as a Coactivator of Stat3. Molecular and Cellular Biology. 30(23). 5456–5472. 85 indexed citations

19.

Proietti, Cecilia J., Wendy Béguelin, María C. Díaz Flaqué, et al.. (2010). Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer. Steroids. 76(4). 381–392. 23 indexed citations

20.

Rivas, Martín A., Mercedes Tkach, Wendy Béguelin, et al.. (2009). Transactivation of ErbB-2 induced by tumor necrosis factor α promotes NF-κB activation and breast cancer cell proliferation. Breast Cancer Research and Treatment. 122(1). 111–124. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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