Kenneth J. Pienta

83.6k total citations · 18 hit papers
675 papers, 49.8k citations indexed

About

Kenneth J. Pienta is a scholar working on Pulmonary and Respiratory Medicine, Oncology and Molecular Biology. According to data from OpenAlex, Kenneth J. Pienta has authored 675 papers receiving a total of 49.8k indexed citations (citations by other indexed papers that have themselves been cited), including 325 papers in Pulmonary and Respiratory Medicine, 233 papers in Oncology and 220 papers in Molecular Biology. Recurrent topics in Kenneth J. Pienta's work include Prostate Cancer Treatment and Research (301 papers), Prostate Cancer Diagnosis and Treatment (93 papers) and Radiopharmaceutical Chemistry and Applications (89 papers). Kenneth J. Pienta is often cited by papers focused on Prostate Cancer Treatment and Research (301 papers), Prostate Cancer Diagnosis and Treatment (93 papers) and Radiopharmaceutical Chemistry and Applications (89 papers). Kenneth J. Pienta collaborates with scholars based in United States, China and Germany. Kenneth J. Pienta's co-authors include Mark A. Rubin, Russell S. Taichman, Sooryanarayana Varambally, Saravana M. Dhanasekaran, Rajal B. Shah, Donald S. Coffey, Arul M. Chinnaiyan, Sarah R. Amend, Arul M. Chinnaiyan and Scott A. Tomlins and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Kenneth J. Pienta

655 papers receiving 48.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

2005 2.8k citations Scott A. Tomlins, Daniel R. Rhodes et al. Science profile →
The polycomb group protein EZH2 is involved in progression of prostate cancer

2002 2.1k citations Sooryanarayana Varambally, Saravana M. Dhanasekaran et al. profile →
Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

2008 1.7k citations Johann S. de Bono, Howard I. Scher et al. Clinical Cancer Research profile →
Delineation of prognostic biomarkers in prostate cancer

2001 1.3k citations Saravana M. Dhanasekaran, Rajal B. Shah et al. profile →
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone.

2002 837 citations Russell S. Taichman, Evan T. Keller et al. profile →
Targeting the tumour stroma to improve cancer therapy

2018 785 citations Kenneth C. Valkenburg, Kenneth J. Pienta et al. profile →
Integrative molecular concept modeling of prostate cancer progression

2006 694 citations Scott A. Tomlins, Rohit Mehra et al. profile →
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

2005 612 citations Sooryanarayana Varambally, Daniel R. Rhodes et al. profile →
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

2007 610 citations Scott A. Tomlins, Saravana M. Dhanasekaran et al. profile →
CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression

2010 605 citations Russell S. Taichman, Kenneth J. Pienta et al. profile →
Measuring quality of life in men with prostate cancer using the Functional Assessment of Cancer Therapy-prostate instrument

1997 565 citations Kenneth J. Pienta et al. profile →
Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

2016 541 citations Kevin J. Cheung, Veena Padmanaban et al. Proceedings of the National Academy of Sciences profile →
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

2011 534 citations Yusuke Shiozawa, Elisabeth A. Pedersen et al. profile →
A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth

2007 524 citations Kenneth J. Pienta et al. profile →
Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide

2017 340 citations Kenneth J. Pienta et al. Journal of Clinical Oncology profile →
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer

2012 336 citations Kenneth J. Pienta, Johann S. de Bono et al. profile →
Updating the Definition of Cancer

2023 263 citations Sarah R. Amend, Robert H. Austin et al. Molecular Cancer Research profile →
A Phase 2/3 Prospective Multicenter Study of the Diagnostic Accuracy of Prostate Specific Membrane Antigen PET/CT with ¹⁸ F-DCFPyL in Prostate Cancer Patients (OSPREY)

2021 244 citations Kenneth J. Pienta, Michael A. Gorin et al. profile →

Peers

Countries citing papers authored by Kenneth J. Pienta

Since Specialization

Citations

This map shows the geographic impact of Kenneth J. Pienta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth J. Pienta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth J. Pienta more than expected).

Fields of papers citing papers by Kenneth J. Pienta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth J. Pienta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth J. Pienta. The network helps show where Kenneth J. Pienta may publish in the future.

Co-authorship network of co-authors of Kenneth J. Pienta

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth J. Pienta. A scholar is included among the top collaborators of Kenneth J. Pienta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth J. Pienta. Kenneth J. Pienta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Oncogenic signaling in the Drosophila prostate-like accessory gland activates a pro-tumorigenic program in the absence of proliferation 2025 ·Disease Models & Mechanisms ·(unknown), Ajai J. Pulianmackal, (unknown), Luke V. Loftus, Sarah R. Amend, Kenneth J. Pienta, Frank C. Cackowski, Laura Buttitta	0
2	Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report 2024 ·Urology Case Reports ·(unknown), Diane K. Reyes, Kenneth J. Pienta	0
3	Identification of a Predictive Genomic Biomarker for Prostate-directed Therapy in Synchronous Low-volume Metastatic Castration-sensitive Prostate Cancer 2023 ·European Urology Oncology ·Philip Sutera, Amol C. Shetty, Yang Song, (unknown), (unknown), Zaker Rana, Kenneth J. Pienta, Felix Y. Feng, Daniel Y. Song, Theodore L. DeWeese, Silke Gillessen, Christopher Sweeney, Nicholas D. James, Gerhardt Attard, Matthew P. Deek, Phuoc T. Tran	6
4	Escherichia coli survival in response to ciprofloxacin antibiotic stress correlates with increased nucleoid length and effective misfolded protein management 2023 ·Royal Society Open Science ·George B. Butler, Julia Bos, Robert H. Austin, Sarah R. Amend, Kenneth J. Pienta	3
5	Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone 2019 ·Journal of Clinical Oncology ·Rana R. McKay, Huihui Ye, Wanling Xie, Rosina T. Lis, Carla Calagua, Zhenwei Zhang, Quoc‐Dien Trinh, Steven L. Chang, Lauren C. Harshman, Ashley E. Ross, Kenneth J. Pienta, Daniel W. Lin, William J. Ellis, Bruce Montgomery, Peter Chang, Andrew A. Wagner, Glenn J. Bubley, Adam S. Kibel, Mary-Ellen Taplin	76
6	AXL Is a Putative Tumor Suppressor and Dormancy Regulator in Prostate Cancer 2018 ·Molecular Cancer Research ·(unknown), Kenneth C. Valkenburg, Sarah R. Amend, Jessica Hicks, Princy Parsana, Gonzalo Torga, Angelo M. De Marzo, Kenneth J. Pienta	40
7	CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes 2018 ·Cancer Research ·Younghun Jung, Frank C. Cackowski, Kenji Yumoto, Ann M. Decker, Jingcheng Wang, Jin Koo Kim, Eunsohl Lee, Yugang Wang, Jae‐Seung Chung, Amy Gursky, Paul H. Krebsbach, Kenneth J. Pienta, Todd M. Morgan, Russell S. Taichman	42
8	TWIST1-WDR5- Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis 2017 ·Cancer Research ·Reem Malek, Rajendra P. Gajula, Russell D. Williams, Belinda Nghiem, Brian W. Simons, Katriana Nugent, Hailun Wang, Kekoa Taparra, (unknown), A‐Rum Yoon, Lawrence D. True, Steven S. An, Theodore L. DeWeese, Ashley E. Ross, Edward M. Schaeffer, Kenneth J. Pienta, Paula J. Hurley, Colm Morrissey, Phuoc T. Tran	93
9	Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters breakdown → 2016 ·Proceedings of the National Academy of Sciences ·Kevin J. Cheung, Veena Padmanaban, Vanesa L. Silvestri, Koen Schipper, Joshua D. Cohen, (unknown), Michael A. Gorin, James E. Verdone, Kenneth J. Pienta, Joel S. Bader, Andrew J. Ewald	541
10	Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis 2014 ·Cancer Research ·Liling Wan, Guohong Hu, Yong Wei, Min Yuan, Roderick T. Bronson, Qifeng Yang, Javed Siddiqui, Kenneth J. Pienta, Yibin Kang	35
11	Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype 2012 ·Molecular Cancer Research ·Jeena Joseph, Yusuke Shiozawa, Younghun Jung, Jin Koo Kim, Elisabeth A. Pedersen, Anjali Mishra, (unknown), Jingcheng Wang, Evan T. Keller, Kenneth J. Pienta, Russell S. Taichman	37
12	Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation 2012 ·Cancer Research ·Steven R. Barthel, (unknown), (unknown), Matthew Opperman, Kempland C. Walley, Leonardo Nimrichter, Monica M. Burdick, Bryan M. Gillard, Michael T. Moser, Klaus Pantel, Barbara A. Foster, Kenneth J. Pienta, Charles J. Dimitroff	60
13	Characterization of Bone Metastases from Rapid Autopsies of Prostate Cancer Patients 2011 ·Clinical Cancer Research ·Rohit Mehra, Chandan Kumar‐Sinha, Sunita Shankar, Robert J. Lonigro, Xiaojun Jing, Neena Philips, Javed Siddiqui, Bo Han, Xuhong Cao, David C. Smith, Rajal B. Shah, Arul M. Chinnaiyan, Kenneth J. Pienta	67
14	Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer 2011 ·Cancer Research ·Terence W. Friedlander, Ritu Roy, Scott A. Tomlins, Vy Ngo, Yasuko Kobayashi, (unknown), Mark A. Rubin, Kenneth J. Pienta, Arul M. Chinnaiyan, Michael Ittmann, Charles J. Ryan, Pamela L. Paris	88
15	Treatment-Dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy 2009 ·Cancer Research ·Mara P. Steinkamp, (unknown), Michele Brogley, Haniya Rehman, Elizabeth W. LaPensee, Saravana M. Dhanasekaran, Matthias D. Hofer, Rainer Kuefer, Arul M. Chinnaiyan, Mark A. Rubin, Kenneth J. Pienta, Diane M. Robins	159
16	A Destructive Cascade Mediated by CCL2 Facilitates Prostate Cancer Growth in Bone 2009 ·Cancer Research ·Xin Li, Robert D. Loberg, Jinhui Liao, Ying Chi, Linda A. Snyder, Kenneth J. Pienta, Laurie K. McCauley	131
17	Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer breakdown → 2008 ·Clinical Cancer Research ·Johann S. de Bono, Howard I. Scher, Bruce Montgomery, Christopher Parker, Michael Craig Miller, H. Tissing, Gerald V. Doyle, Leon W.M.M. Terstappen, Kenneth J. Pienta, Derek Raghavan	1744
18	Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa 2008 ·Molecular Cancer Therapeutics ·Yang Meng, Wenhua Tang, Yao Dai, Xiaoqing Wu, Meilan Liu, Qing Ji, Min Ji, Kenneth J. Pienta, Theodore S. Lawrence, Liang Xu	167
19	TMPRSS2:ERG Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer 2006 ·Cancer Research ·Sven Perner, Francesca Demichelis, Rameen Beroukhim, Folke Schmidt, Juan Miguel Mosquera, Sunita R. Setlur, Joëlle Tchinda, Scott A. Tomlins, Matthias D. Hofer, Kenneth J. Pienta, Rainer Kuefer, Robert L. Vessella, Xiao Sun, Matthew Meyerson, Charles Lee, William R. Sellers, Arul M. Chinnaiyan, Mark A. Rubin	388
20	Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer breakdown → 2005 ·Science ·Scott A. Tomlins, Daniel R. Rhodes, Sven Perner, Saravana M. Dhanasekaran, Rohit Mehra, Xiao Sun, Sooryanarayana Varambally, Xuhong Cao, Joëlle Tchinda, Rainer Kuefer, Charles Lee, James E. Montie, Rajal B. Shah, Kenneth J. Pienta, Mark A. Rubin, Arul M. Chinnaiyan	2820

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