Patrick J. Lupardus

7.8k total citations · 2 hit papers
54 papers, 4.8k citations indexed

About

Patrick J. Lupardus is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Patrick J. Lupardus has authored 54 papers receiving a total of 4.8k indexed citations (citations by other indexed papers that have themselves been cited), including 31 papers in Molecular Biology, 26 papers in Oncology and 22 papers in Immunology. Recurrent topics in Patrick J. Lupardus's work include Cytokine Signaling Pathways and Interactions (15 papers), Immune Cell Function and Interaction (9 papers) and DNA Repair Mechanisms (7 papers). Patrick J. Lupardus is often cited by papers focused on Cytokine Signaling Pathways and Interactions (15 papers), Immune Cell Function and Interaction (9 papers) and DNA Repair Mechanisms (7 papers). Patrick J. Lupardus collaborates with scholars based in United States, France and United Kingdom. Patrick J. Lupardus's co-authors include K. Christopher García, Karlene A. Cimprich, Zora Modrušan, Heidi J.A. Wallweber, Domagoj Vucic, Xinquan Wang, Sherry L. LaPorte, Ali A. Zarrin, Katherine Bao and Ryan Ferrao and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Patrick J. Lupardus

50 papers receiving 4.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

2014 881 citations Mahesh Yadav, Suchit Jhunjhunwala et al. Nature profile →
Kinase inhibition in autoimmunity and inflammation

2020 305 citations Patrick J. Lupardus et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Patrick J. Lupardus United States	34	2.6k	1.9k	1.8k	432	414	54	4.8k
Bharat Joshi United States	42	2.8k 1.1×	1.1k 0.6×	1.6k 0.9×	488 1.1×	352 0.9×	109	5.5k
Terry Farrah United States	22	3.0k 1.2×	855 0.5×	2.0k 1.1×	610 1.4×	212 0.5×	28	5.8k
Jeffrey J. Babon Australia	38	2.7k 1.1×	1.8k 1.0×	2.0k 1.1×	496 1.1×	99 0.2×	96	5.6k
Leslie J. Berg United States	50	2.2k 0.9×	2.0k 1.1×	5.6k 3.0×	324 0.8×	478 1.2×	114	7.9k
Wolfgang W. Schamel Germany	44	2.4k 0.9×	1.6k 0.9×	3.6k 1.9×	228 0.5×	768 1.9×	141	6.3k
Kuo‐I Lin Taiwan	37	2.5k 1.0×	737 0.4×	3.1k 1.7×	569 1.3×	196 0.5×	80	5.8k
Simon N. Willis Australia	24	4.9k 1.9×	1.7k 0.9×	2.0k 1.1×	626 1.4×	191 0.5×	36	7.2k
Allen Oliff United States	43	4.1k 1.6×	2.6k 1.4×	883 0.5×	562 1.3×	439 1.1×	107	6.7k
Karen Kozarsky United States	40	3.9k 1.5×	1.2k 0.7×	837 0.5×	657 1.5×	253 0.6×	74	7.3k
Nicolai S. C. van Oers United States	35	1.4k 0.6×	922 0.5×	3.1k 1.7×	249 0.6×	525 1.3×	81	4.4k

Countries citing papers authored by Patrick J. Lupardus

Since Specialization

Citations

This map shows the geographic impact of Patrick J. Lupardus's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick J. Lupardus with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick J. Lupardus more than expected).

Fields of papers citing papers by Patrick J. Lupardus

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick J. Lupardus. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick J. Lupardus. The network helps show where Patrick J. Lupardus may publish in the future.

Co-authorship network of co-authors of Patrick J. Lupardus

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick J. Lupardus. A scholar is included among the top collaborators of Patrick J. Lupardus based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick J. Lupardus. Patrick J. Lupardus is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Trenker, Raphael, Deepti Rokkam, Andrew Morin, et al.. (2025). Structure-Guided Stapling of Dimeric Conformations and Linker Engineering Enhance Thermostability and Fine-Tune Activity of Bispecific VHH Cytokine Agonists. Antibodies. 14(3). 74–74.

Aspuria, Paul‐Joseph, Ivan Cheng, Navneet Ratti, et al.. (2023). 228 Engineered human IL-2/IL-2Rß orthogonal pairs selectively enhance anti-GPC3 CAR T cells in vivo to drive complete responses in solid epithelial tumor models. SHILAP Revista de lepidopterología. A260–A260. 1 indexed citations

Glassman, Caleb R., Naotaka Tsutsumi, Robert A. Saxton, et al.. (2022). Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation. Science. 376(6589). 163–169. 101 indexed citations

Glassman, Caleb R., Kevin M. Jude, Leon Su, et al.. (2021). Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells. Cell. 184(4). 983–999.e24. 113 indexed citations

Aspuria, Paul‐Joseph, Sandro Vivona, Michele Bauer, et al.. (2021). An orthogonal IL-2 and IL-2Rβ system drives persistence and activation of CAR T cells and clearance of bulky lymphoma. Science Translational Medicine. 13(625). eabg7565–eabg7565. 61 indexed citations

Fong, Rina, Kimberly K. Kajihara, Isidro Hötzel, et al.. (2018). Structural investigation of humanS. aureus-targeting antibodies that bind wall teichoic acid. mAbs. 10(7). 1–13. 24 indexed citations

Ferrao, Ryan, Heidi J.A. Wallweber, & Patrick J. Lupardus. (2018). Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation. eLife. 7. 42 indexed citations

Chai, Ning, Lee R. Swem, Summer Park, et al.. (2017). A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action. Nature Communications. 8(1). 14234–14234. 49 indexed citations

Wang, Tzu-Ming, Brandon M. Brown, Lunbin Deng, et al.. (2017). A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain. Neuropharmacology. 121. 204–218. 32 indexed citations

10.

Hackos, David H., Patrick J. Lupardus, Teddy Grand, et al.. (2016). Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron. 89(5). 983–999. 139 indexed citations

11.

Yadav, Mahesh, Suchit Jhunjhunwala, Qui Phung, et al.. (2014). Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 515(7528). 572–576. 881 indexed citations breakdown →

12.

Ramirez-Carrozzi, Vladimir, Amy Dressen, Patrick J. Lupardus, Brian L. Yaspan, & Rajita Pappu. (2014). Functional analysis of protective IL1RL1 variants associated with asthma risk. Journal of Allergy and Clinical Immunology. 135(4). 1080–1083.e3. 6 indexed citations

13.

Junttila, Ilkka, Rémi J. Creusot, Ignacio Moraga, et al.. (2012). Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines. Nature Chemical Biology. 8(12). 990–998. 66 indexed citations

14.

Shen, Aimee, Patrick J. Lupardus, Malte Gersch, et al.. (2011). Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins. Nature Structural & Molecular Biology. 18(3). 364–371. 51 indexed citations

15.

Puri, Aaron W., Patrick J. Lupardus, Edgar Deu, et al.. (2010). Rational Design of Inhibitors and Activity-Based Probes Targeting Clostridium difficile Virulence Factor TcdB. Chemistry & Biology. 17(11). 1201–1211. 51 indexed citations

16.

Lupardus, Patrick J., Michael E. Birnbaum, & K. Christopher García. (2010). Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2. Structure. 18(3). 332–342. 120 indexed citations

17.

Shen, Aimee, Patrick J. Lupardus, Montse Morell, et al.. (2009). Simplified, Enhanced Protein Purification Using an Inducible, Autoprocessing Enzyme Tag. PLoS ONE. 4(12). e8119–e8119. 67 indexed citations

18.

Lupardus, Patrick J. & K. Christopher García. (2008). The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12. Journal of Molecular Biology. 382(4). 931–941. 111 indexed citations

19.

Bomgarden, Ryan, Patrick J. Lupardus, Deena V. Soni, et al.. (2006). Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase η on ATR checkpoint signaling. The EMBO Journal. 25(11). 2605–2614. 77 indexed citations

20.

Wilke, Russell A., et al.. (1999). K⁺ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors. The Journal of Physiology. 517(2). 391–406. 50 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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