Patrick J. Casey

23.8k total citations · 8 hit papers
247 papers, 19.3k citations indexed

About

Patrick J. Casey is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Patrick J. Casey has authored 247 papers receiving a total of 19.3k indexed citations (citations by other indexed papers that have themselves been cited), including 168 papers in Molecular Biology, 45 papers in Oncology and 44 papers in Cell Biology. Recurrent topics in Patrick J. Casey's work include Protein Kinase Regulation and GTPase Signaling (66 papers), Ubiquitin and proteasome pathways (34 papers) and Receptor Mechanisms and Signaling (18 papers). Patrick J. Casey is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (66 papers), Ubiquitin and proteasome pathways (34 papers) and Receptor Mechanisms and Signaling (18 papers). Patrick J. Casey collaborates with scholars based in United States, Singapore and New Zealand. Patrick J. Casey's co-authors include Alfred G. Gilman, Miguel C. Seabra, Timothy A. Fields, Mei Wang, Janice E. Buss, L.S. Beese, John F. Moomaw, Patrick Kelly, Channing J. Der and Michael S. Brown and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Patrick J. Casey

246 papers receiving 18.9k citations

Hit Papers

PROTEIN PRENYLATION: Molecular Mechanisms and Functional ... 1988 2026 2000 2013 1996 1989 1990 1995 1996 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. PROTEIN PRENYLATION: Molecular Mechanisms and Functional Consequences
    1996 1.7k citations Patrick J. Casey et al. Annual Review of Biochemistry profile →
  2. p21ras is modified by a farnesyl isoprenoid.
    1989 735 citations Patrick J. Casey et al. Proceedings of the National Academy of Sciences profile →
  3. Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
    1990 699 citations Patrick J. Casey et al. profile →
  4. Protein Lipidation in Cell Signaling
    1995 645 citations Patrick J. Casey profile →
  5. Protein Prenyltransferases
    1996 611 citations Patrick J. Casey et al. Journal of Biological Chemistry profile →
  6. Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors
    1992 605 citations Patrick J. Casey et al. profile →
  7. G protein involvement in receptor-effector coupling.
    1988 516 citations Patrick J. Casey et al. Journal of Biological Chemistry profile →
  8. G proteins control diverse pathways of transmembrane signaling 1
    1989 344 citations Patrick J. Casey et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Patrick J. Casey United States 74 14.8k 3.5k 3.4k 1.8k 1.4k 247 19.3k
Stevan R. Hubbard United States 52 9.6k 0.6× 3.7k 1.0× 2.5k 0.7× 899 0.5× 771 0.6× 89 14.4k
Lorenzo A. Pinna Italy 74 15.9k 1.1× 2.8k 0.8× 3.4k 1.0× 784 0.4× 757 0.5× 448 21.6k
George Thomas Switzerland 83 18.4k 1.2× 2.9k 0.8× 3.0k 0.9× 1.5k 0.8× 1.8k 1.3× 162 24.4k
Robert Roskoski United States 57 9.9k 0.7× 1.3k 0.4× 4.1k 1.2× 1.2k 0.7× 1.4k 1.0× 173 16.3k
Edwin G. Krebs United States 71 14.4k 1.0× 3.9k 1.1× 1.9k 0.6× 1.4k 0.8× 1.4k 1.0× 150 20.6k
Zhou Songyang United States 69 15.1k 1.0× 2.8k 0.8× 2.8k 0.8× 1.3k 0.7× 1.3k 0.9× 193 19.9k
Peter J. Parker United Kingdom 95 25.3k 1.7× 7.6k 2.2× 3.9k 1.2× 3.0k 1.7× 2.0k 1.5× 406 33.7k
Natalie G. Ahn United States 63 13.1k 0.9× 2.7k 0.8× 2.0k 0.6× 998 0.5× 1.2k 0.9× 170 16.6k
Len Neckers United States 85 19.4k 1.3× 3.0k 0.8× 3.1k 0.9× 931 0.5× 3.0k 2.1× 248 24.9k
Yoshihide Tsujimoto Japan 85 18.8k 1.3× 2.8k 0.8× 4.3k 1.3× 2.0k 1.1× 2.4k 1.7× 184 28.6k

Countries citing papers authored by Patrick J. Casey

Since Specialization
Citations

This map shows the geographic impact of Patrick J. Casey's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick J. Casey with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick J. Casey more than expected).

Fields of papers citing papers by Patrick J. Casey

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick J. Casey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick J. Casey. The network helps show where Patrick J. Casey may publish in the future.

Co-authorship network of co-authors of Patrick J. Casey

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick J. Casey. A scholar is included among the top collaborators of Patrick J. Casey based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick J. Casey. Patrick J. Casey is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Casey, Patrick J., et al.. (2024). RAB4A is a master regulator of cancer cell stemness upstream of NUMB–NOTCH signaling. Cell Death and Disease. 15(10). 778–778. 2 indexed citations
2.
Rasheed, Suhail Ahmed Kabeer, Lijin Wang, Sujoy Ghosh, et al.. (2024). GNA13 suppresses proliferation of ER+ breast cancer cells via ERα dependent upregulation of the MYC oncogene. Breast Cancer Research. 26(1). 113–113. 1 indexed citations
3.
Tang, Jingyi, Patrick J. Casey, & Mei Wang. (2021). Suppression of isoprenylcysteine carboxylmethyltransferase compromises DNA damage repair. Life Science Alliance. 4(12). e202101144–e202101144. 1 indexed citations
4.
Casey, Patrick J., et al.. (2019). Surgically positioned paravertebral catheters and postoperative analgesia after open abdominal aortic aneurysm repair. Journal of Vascular Surgery. 70(5). 1479–1487. 7 indexed citations
5.
Manu, Kanjoormana Aryan, et al.. (2017). Inhibition of Isoprenylcysteine Carboxylmethyltransferase Induces Cell-Cycle Arrest and Apoptosis through p21 and p21-Regulated BNIP3 Induction in Pancreatic Cancer. Molecular Cancer Therapeutics. 16(5). 914–923. 48 indexed citations
6.
Wang, Mei & Patrick J. Casey. (2016). Protein prenylation: unique fats make their mark on biology. Nature Reviews Molecular Cell Biology. 17(2). 110–122. 377 indexed citations
7.
Hultman, Rainbo, et al.. (2013). Gαz regulates BDNF-induction of axon growth in cortical neurons. Molecular and Cellular Neuroscience. 58. 53–61. 12 indexed citations
8.
Bailey, Candice L., Patrick Kelly, & Patrick J. Casey. (2009). Activation of Rap1 Promotes Prostate Cancer Metastasis. Cancer Research. 69(12). 4962–4968. 119 indexed citations
9.
Spencer, Wendy, et al.. (2008). Review of the Current Status of Thresholds/Withdrawal Time Guidelines for Therapeutic Medications in Performance Horses. Proceedings of the ... Annual Convention - American Association of Equine Practitioners.. 54. 29–37. 3 indexed citations
10.
Sjögren, Anna-Karin, Karin Andersson, Meng Liu, et al.. (2007). GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS–induced lung cancer. Journal of Clinical Investigation. 117(5). 1294–1304. 85 indexed citations
11.
Winter-Vann, Ann M., Rudi Baron, Waihay J. Wong, et al.. (2005). A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proceedings of the National Academy of Sciences. 102(12). 4336–4341. 154 indexed citations
12.
Bergö, Martin O., Bryant J. Gavino, Christine Hong, et al.. (2004). Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. Journal of Clinical Investigation. 113(4). 539–550. 135 indexed citations
13.
Meng, Jingwei & Patrick J. Casey. (2002). Activation of Gz Attenuates Rap1-mediated Differentiation of PC12 Cells. Journal of Biological Chemistry. 277(45). 43417–43424. 46 indexed citations
14.
Breier, Bernhard H., et al.. (2002). Blood Plasma Concentrations of Insulin-like Growth Factor-I (IGF-I) in Resting Standardbred Horses. The Veterinary Journal. 163(1). 45–50. 24 indexed citations
15.
Casey, Patrick J., et al.. (1997). Evidence for a Catalytic Role of Zinc in Protein Farnesyltransferase. Journal of Biological Chemistry. 272(1). 20–23. 113 indexed citations
16.
Casey, Patrick J., et al.. (1996). PROTEIN PRENYLATION: Molecular Mechanisms and Functional Consequences. Annual Review of Biochemistry. 65(1). 241–269. 1663 indexed citations breakdown →
17.
Fields, Timothy A. & Patrick J. Casey. (1995). Phosphorylation of Gzα by Protein Kinase C Blocks Interaction with the βγ Complex. Journal of Biological Chemistry. 270(39). 23119–23125. 81 indexed citations
18.
Casey, Patrick J.. (1995). Presenting Teachers With A Model for Technological Innovation. Society for Information Technology & Teacher Education International Conference. 1995(1). 855–858. 5 indexed citations
19.
Casey, Patrick J., Robert B. Hillman, Kathryn Robertson, et al.. (1993). Validation of an Acrosomal Stain for Equine Sperm that Differentiates between Living and Dead Sperm. Journal of Andrology. 14(4). 289–297. 72 indexed citations
20.
Gravance, C.G., et al.. (1993). Automated morphometric analysis of stallion spermatozoa. American Journal of Veterinary Research. 54(11). 1808–1811. 48 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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