Miguel C. Seabra

26.0k total citations · 9 hit papers
190 papers, 20.5k citations indexed

About

Miguel C. Seabra is a scholar working on Molecular Biology, Cell Biology and Ophthalmology. According to data from OpenAlex, Miguel C. Seabra has authored 190 papers receiving a total of 20.5k indexed citations (citations by other indexed papers that have themselves been cited), including 129 papers in Molecular Biology, 115 papers in Cell Biology and 28 papers in Ophthalmology. Recurrent topics in Miguel C. Seabra's work include Cellular transport and secretion (96 papers), Retinal Development and Disorders (62 papers) and Retinal Diseases and Treatments (28 papers). Miguel C. Seabra is often cited by papers focused on Cellular transport and secretion (96 papers), Retinal Development and Disorders (62 papers) and Retinal Diseases and Treatments (28 papers). Miguel C. Seabra collaborates with scholars based in United Kingdom, United States and Portugal. Miguel C. Seabra's co-authors include Alistair N. Hume, José B. Pereira‐Leal, Patrick J. Casey, Joseph L. Goldstein, Michael S. Brown, Tanya Tolmachova, Christina Wasmeier, Duarte C. Barral, Graça Raposo and Yuval Reiss and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Miguel C. Seabra

189 papers receiving 20.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rab27a and Rab27b control different steps of the exosome secretion pathway

2009 2.1k citations Matías Ostrowski, Sophie Krumeich et al. profile →
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1990 699 citations Miguel C. Seabra et al. profile →
NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

2006 689 citations Miguel C. Seabra et al. profile →
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial

2014 622 citations Tanya Tolmachova, Andrew R. Webster et al. profile →
Evolution of the rab family of small GTP-binding proteins

2001 619 citations Miguel C. Seabra et al. profile →
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

2015 617 citations Tanya Tolmachova, Miguel C. Seabra et al. Nature Communications profile →
Protein Prenyltransferases

1996 611 citations Miguel C. Seabra et al. Journal of Biological Chemistry profile →
Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

2012 516 citations Angélique Bobrie, Sophie Krumeich et al. Cancer Research profile →
MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

2014 492 citations Tanya Tolmachova, Miguel C. Seabra et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Miguel C. Seabra United Kingdom	76	14.6k	8.0k	2.9k	2.7k	1.6k	190	20.5k
Jun‐Lin Guan United States	78	13.2k 0.9×	7.3k 0.9×	2.3k 0.8×	3.6k 1.3×	261 0.2×	202	24.9k
Enrique Rodríguez-Boulan United States	70	10.1k 0.7×	6.8k 0.8×	1.4k 0.5×	502 0.2×	999 0.6×	161	14.9k
Wanjin Hong Singapore	81	12.5k 0.9×	11.7k 1.5×	1.8k 0.6×	1.1k 0.4×	141 0.1×	323	20.9k
Dietmar Vestweber Germany	101	13.9k 1.0×	4.4k 0.6×	9.2k 3.2×	2.5k 0.9×	502 0.3×	323	30.1k
Shoukat Dedhar Canada	92	15.8k 1.1×	6.2k 0.8×	3.2k 1.1×	4.1k 1.5×	180 0.1×	260	26.4k
Yi Zheng United States	83	14.1k 1.0×	6.2k 0.8×	3.2k 1.1×	1.6k 0.6×	125 0.1×	364	21.5k
Alan R. Prescott United Kingdom	67	9.2k 0.6×	2.7k 0.3×	2.1k 0.7×	636 0.2×	248 0.2×	204	13.9k
Gary Bokoch United States	99	20.4k 1.4×	10.5k 1.3×	6.8k 2.4×	1.7k 0.6×	122 0.1×	220	31.2k
Bengt Westermark Sweden	86	16.4k 1.1×	4.0k 0.5×	3.5k 1.2×	4.2k 1.5×	251 0.2×	340	29.1k
Philip D. Stahl United States	78	12.6k 0.9×	6.0k 0.7×	4.8k 1.7×	2.1k 0.8×	87 0.1×	226	20.1k

Countries citing papers authored by Miguel C. Seabra

Since Specialization

Citations

This map shows the geographic impact of Miguel C. Seabra's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Miguel C. Seabra with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Miguel C. Seabra more than expected).

Fields of papers citing papers by Miguel C. Seabra

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Miguel C. Seabra. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Miguel C. Seabra. The network helps show where Miguel C. Seabra may publish in the future.

Co-authorship network of co-authors of Miguel C. Seabra

This figure shows the co-authorship network connecting the top 25 collaborators of Miguel C. Seabra. A scholar is included among the top collaborators of Miguel C. Seabra based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Miguel C. Seabra. Miguel C. Seabra is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Lemos, Luísa de, Michael J. Hall, Ana S. Falcão, et al.. (2024). Modeling Choroideremia Disease with Isogenic Induced Pluripotent Stem Cells. Stem Cells and Development. 33(19-20). 528–539. 3 indexed citations

Antas, Pedro, et al.. (2023). Toward low-cost gene therapy: mRNA-based therapeutics for treatment of inherited retinal diseases. Trends in Molecular Medicine. 30(2). 136–146. 9 indexed citations

Rosado-Ramos, Rita, Alexandre Foito, Mafalda Lopes‐da‐Silva, et al.. (2023). Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage. Nature Communications. 14(1). 1918–1918. 15 indexed citations

Hall, Michael J., et al.. (2022). Reconstructed human pigmented skin/epidermis models achieve epidermal pigmentation through melanocore transfer. Pigment Cell & Melanoma Research. 35(4). 425–435. 27 indexed citations

Ramalho, José S., et al.. (2022). RAB3A Regulates Melanin Exocytosis and Transfer Induced by Keratinocyte-Conditioned Medium. SHILAP Revista de lepidopterología. 2(5). 100139–100139. 7 indexed citations

Seabra, Miguel C., et al.. (2020). Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1. Proceedings of the National Academy of Sciences. 117(27). 15684–15693. 31 indexed citations

Evans, Richard D., Deborah A. Briggs, Marta Cantero, et al.. (2019). Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a. Journal of Cell Science. 132(9). 9 indexed citations

Burgoyne, Thomas, et al.. (2015). Rod disc renewal occurs by evagination of the ciliary plasma membrane that makes cadherin-based contacts with the inner segment. Proceedings of the National Academy of Sciences. 112(52). 15922–15927. 82 indexed citations

Tracey‐White, Dhani, Clare E. Futter, Anthony T. Moore, et al.. (2014). Translational bypass therapy using ataluren to treat nonsense-mediated choroideremia. Investigative Ophthalmology & Visual Science. 55(13). 3302–3302. 2 indexed citations

10.

Tarafder, Abul K., et al.. (2014). A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes. PLoS ONE. 9(7). e102851–e102851. 5 indexed citations

11.

Burgoyne, Thomas, Richard Jolly, Belén Martı́n-Martı́n, et al.. (2013). Expression of OA1 limits the fusion of a subset of MVBs with lysosomes; a mechanism likely involved in the initial biogenesis of melanosomes. Journal of Cell Science. 126(Pt 22). 5143–52. 27 indexed citations

12.

Bobrie, Angélique, Sophie Krumeich, Fabien Reyal, et al.. (2012). Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression. Cancer Research. 72(19). 4920–4930. 516 indexed citations breakdown →

13.

Hendrix, An, Kathleen Lambein, Wendy Westbroek, et al.. (2012). An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue. The International Journal of Developmental Biology. 56(5). 363–368. 6 indexed citations

14.

Nightingale, Thomas D., et al.. (2011). Myosin Va Acts in Concert with Rab27a and MyRIP to Regulate Acute Von‐Willebrand Factor Release from Endothelial Cells. Traffic. 12(10). 1371–1382. 63 indexed citations

15.

Johnson, Jennifer L., Agnieszka A. Brzezinska, Tanya Tolmachova, et al.. (2009). Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms. Traffic. 11(4). 533–547. 88 indexed citations

16.

Baron, Rudi, Richard Tavaré, Ana C. Figueiredo, et al.. (2008). Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase. Journal of Biological Chemistry. 284(11). 6861–6868. 46 indexed citations

17.

Anand, Vibha, Duarte C. Barral, Yong Zeng, et al.. (2003). Gene therapy for choroideremia: in vitro rescue mediated by recombinant adenovirus. Vision Research. 43(8). 919–926. 44 indexed citations

18.

Barral, Duarte C., José S. Ramalho, Alistair N. Hume, et al.. (2002). Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome. Journal of Clinical Investigation. 110(2). 247–257. 129 indexed citations

19.

Marks, Michael S. & Miguel C. Seabra. (2001). The melanosome: membrane dynamics in black and white. Nature Reviews Molecular Cell Biology. 2(10). 738–748. 359 indexed citations

20.

Coxon, Fraser P., Miep Helfrich, Banafshé Larijani, et al.. (2001). Identification of a Novel Phosphonocarboxylate Inhibitor of Rab Geranylgeranyl Transferase That Specifically Prevents Rab Prenylation in Osteoclasts and Macrophages. Journal of Biological Chemistry. 276(51). 48213–48222. 136 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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