Monika Wierdl

2.2k total citations
29 papers, 1.6k citations indexed

About

Monika Wierdl is a scholar working on Molecular Biology, Pharmacology and Computational Theory and Mathematics. According to data from OpenAlex, Monika Wierdl has authored 29 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 17 papers in Pharmacology and 8 papers in Computational Theory and Mathematics. Recurrent topics in Monika Wierdl's work include Cholinesterase and Neurodegenerative Diseases (17 papers), Computational Drug Discovery Methods (8 papers) and Cancer therapeutics and mechanisms (8 papers). Monika Wierdl is often cited by papers focused on Cholinesterase and Neurodegenerative Diseases (17 papers), Computational Drug Discovery Methods (8 papers) and Cancer therapeutics and mechanisms (8 papers). Monika Wierdl collaborates with scholars based in United States and Canada. Monika Wierdl's co-authors include Thomas D. Petes, Philip M. Potter, Margaret Dominska, Mary K. Danks, Christopher L. Morton, Carol C. Edwards, Janice L. Hyatt, Lyudmila Tsurkan, Randy M. Wadkins and M. Jason Hatfield and has published in prestigious journals such as Proceedings of the National Academy of Sciences, PLoS ONE and Biochemistry.

In The Last Decade

Monika Wierdl

29 papers receiving 1.6k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Monika Wierdl United States 20 876 375 305 299 249 29 1.6k
Seungil Han United States 27 1.6k 1.9× 175 0.5× 193 0.6× 206 0.7× 261 1.0× 50 2.8k
Petra Janning Germany 28 1.4k 1.6× 366 1.0× 194 0.6× 128 0.4× 550 2.2× 85 2.3k
M. Jason Hatfield United States 18 635 0.7× 353 0.9× 420 1.4× 113 0.4× 204 0.8× 27 1.4k
Catherine A. Prody Israel 18 964 1.1× 516 1.4× 249 0.8× 157 0.5× 103 0.4× 23 1.6k
Russell B. Lingham United States 27 824 0.9× 576 1.5× 101 0.3× 127 0.4× 460 1.8× 50 1.7k
Victoria Magrioti Greece 18 1.1k 1.3× 239 0.6× 262 0.9× 46 0.2× 301 1.2× 42 1.9k
Isaac M. Westwood United Kingdom 26 1.1k 1.2× 93 0.2× 113 0.4× 116 0.4× 207 0.8× 45 1.6k
Lucı́lia Saraiva Portugal 26 1.2k 1.4× 155 0.4× 65 0.2× 243 0.8× 390 1.6× 109 2.1k
Rilei Yu China 25 1.6k 1.9× 186 0.5× 99 0.3× 49 0.2× 262 1.1× 128 2.4k
Qi Shen China 21 817 0.9× 265 0.7× 141 0.5× 167 0.6× 112 0.4× 60 1.5k

Countries citing papers authored by Monika Wierdl

Since Specialization
Citations

This map shows the geographic impact of Monika Wierdl's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Monika Wierdl with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Monika Wierdl more than expected).

Fields of papers citing papers by Monika Wierdl

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Monika Wierdl. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Monika Wierdl. The network helps show where Monika Wierdl may publish in the future.

Co-authorship network of co-authors of Monika Wierdl

This figure shows the co-authorship network connecting the top 25 collaborators of Monika Wierdl. A scholar is included among the top collaborators of Monika Wierdl based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Monika Wierdl. Monika Wierdl is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wierdl, Monika, Lyudmila Tsurkan, Liying Chi, et al.. (2018). Targeting ALK in pediatric RMS does not induce antitumor activity in vivo. Cancer Chemotherapy and Pharmacology. 82(2). 251–263. 7 indexed citations
2.
Wierdl, Monika, Lyudmila Tsurkan, M. Jason Hatfield, & Philip M. Potter. (2016). Tumour‐selective targeting of drug metabolizing enzymes to treat metastatic cancer. British Journal of Pharmacology. 173(19). 2811–2818. 4 indexed citations
3.
Hossain, Delwar, et al.. (2011). Global and local molecular dynamics of a bacterial carboxylesterase provide insight into its catalytic mechanism. Journal of Molecular Modeling. 18(6). 2869–2883. 11 indexed citations
4.
Hemmert, Andrew, Tamara C. Otto, Monika Wierdl, et al.. (2010). Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin. Molecular Pharmacology. 77(4). 508–516. 40 indexed citations
5.
Wierdl, Monika, et al.. (2008). Modifications of human carboxylesterase for improved prodrug activation. Expert Opinion on Drug Metabolism & Toxicology. 4(9). 1153–1165. 29 indexed citations
6.
Wierdl, Monika, Lyudmila Tsurkan, Janice L. Hyatt, et al.. (2008). An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11. Cancer Gene Therapy. 15(3). 183–192. 43 indexed citations
7.
Hyatt, Janice L., M. Jason Hatfield, Lyudmila Tsurkan, et al.. (2007). Selective Inhibition of Carboxylesterases by Isatins, Indole-2,3-diones. Journal of Medicinal Chemistry. 50(8). 1876–1885. 60 indexed citations
8.
Hyatt, Janice L., Carol C. Edwards, Lyudmila Tsurkan, et al.. (2007). Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils. Bioorganic & Medicinal Chemistry. 15(11). 3801–3817. 37 indexed citations
9.
Hyatt, Janice L., Lyudmila Tsurkan, Monika Wierdl, et al.. (2006). Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity. Molecular Cancer Therapeutics. 5(9). 2281–2288. 41 indexed citations
10.
Wadkins, Randy M., Janice L. Hyatt, Xin Wei, et al.. (2005). Identification and Characterization of Novel Benzil (Diphenylethane-1,2-dione) Analogues as Inhibitors of Mammalian Carboxylesterases. Journal of Medicinal Chemistry. 48(8). 2906–2915. 169 indexed citations
11.
Hyatt, Janice L., Randy M. Wadkins, Kyoung Jin P. Yoon, et al.. (2005). Inhibition of Carboxylesterases by Benzil (Diphenylethane-1,2-dione) and Heterocyclic Analogues Is Dependent upon the Aromaticity of the Ring and the Flexibility of the Dione Moiety. Journal of Medicinal Chemistry. 48(17). 5543–5550. 61 indexed citations
12.
Wierdl, Monika & Philip M. Potter. (2005). Update on gene therapy approaches for cancer.. PubMed. 4(4). 294–9. 4 indexed citations
13.
Wierdl, Monika, et al.. (2004). Molecular Modeling of CPT-11 Metabolism by Carboxylesterases (CEs):  Use of pnb CE as a Model. Biochemistry. 43(7). 1874–1882. 17 indexed citations
14.
Wierdl, Monika, Christopher L. Morton, Janardhan Sampath, et al.. (2003). Carboxylesterase-Mediated Sensitization of Human Tumor Cells to CPT-11 Cannot Override ABCG2-Mediated Drug Resistance. Molecular Pharmacology. 64(2). 279–288. 36 indexed citations
15.
Wierdl, Monika, Christopher L. Morton, Linda C. Harris, et al.. (2003). p53-Mediated Regulation of Expression of a Rabbit Liver Carboxylesterase Confers Sensitivity to 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). Journal of Pharmacology and Experimental Therapeutics. 304(2). 699–705. 1 indexed citations
16.
Wierdl, Monika, et al.. (2001). Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase.. PubMed. 61(13). 5078–82. 54 indexed citations
17.
Wierdl, Monika, et al.. (2000). Activation of CPT-11 in mice: identification and analysis of a highly effective plasma esterase.. PubMed. 60(15). 4206–10. 61 indexed citations
18.
Wierdl, Monika, Christopher L. Morton, Mary K. Danks, & Philip M. Potter. (2000). Isolation and characterization of a cDNA encoding a horse liver butyrylcholinesterase. Biochemical Pharmacology. 59(7). 773–781. 16 indexed citations
19.
Potter, Philip M., Judith S. Wolverton, Christopher L. Morton, Monika Wierdl, & Mary K. Danks. (1998). Cellular localization domains of a rabbit and a human carboxylesterase: influence on irinotecan (CPT-11) metabolism by the rabbit enzyme.. PubMed. 58(16). 3627–32. 68 indexed citations
20.
Wierdl, Monika, Margaret Dominska, & Thomas D. Petes. (1997). Microsatellite Instability in Yeast: Dependence on the Length of the Microsatellite. Genetics. 146(3). 769–779. 336 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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