Michelle L. Block

18.8k total citations · 7 hit papers
61 papers, 14.8k citations indexed

About

Michelle L. Block is a scholar working on Neurology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Michelle L. Block has authored 61 papers receiving a total of 14.8k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Neurology, 18 papers in Cellular and Molecular Neuroscience and 16 papers in Physiology. Recurrent topics in Michelle L. Block's work include Neuroinflammation and Neurodegeneration Mechanisms (45 papers), Air Quality and Health Impacts (14 papers) and Nerve injury and regeneration (12 papers). Michelle L. Block is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (45 papers), Air Quality and Health Impacts (14 papers) and Nerve injury and regeneration (12 papers). Michelle L. Block collaborates with scholars based in United States, China and Taiwan. Michelle L. Block's co-authors include Jau‐Shyong Hong, Luigi Zecca, Lilian Calderón‐Garcidueñas, Melinda E. Lull, Liya Qin, Xuefei Wu, Yuxin Liu, Belinda Wilson, George R. Breese and Fulton T. Crews and has published in prestigious journals such as Journal of Biological Chemistry, The Journal of Experimental Medicine and Journal of Neuroscience.

In The Last Decade

Michelle L. Block

60 papers receiving 14.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

2006 3.3k citations Michelle L. Block, Luigi Zecca et al. Nature reviews. Neuroscience profile →
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

2007 1.7k citations Michelle L. Block, Yuxin Liu et al. Glia profile →
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

2005 1.3k citations Michelle L. Block, Jau‐Shyong Hong profile →
Air pollution: mechanisms of neuroinflammation and CNS disease

2009 1.2k citations Michelle L. Block, Lilian Calderón‐Garcidueñas Trends in Neurosciences profile →
Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease

2005 1.0k citations Michelle L. Block, Belinda Wilson et al. profile →
Microglial Activation and Chronic Neurodegeneration

2010 818 citations Melinda E. Lull, Michelle L. Block profile →
NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

2004 515 citations Yuxin Liu, Sung‐Jen Wei et al. profile →

Peers

Michelle L. Block

NEURO

CMN

HTM

PHYSI

Maria Grazia De Simoni Italy

Todd E. Morgan United States

Diogo O. Souza Brazil

Belinda Wilson United States

Masashi Kitazawa United States

Debomoy K. Lahiri United States

Tomás R. Guilarte United States

James P. O’Callaghan United States

Michael A. Schwarzschild United States

Anumantha G. Kanthasamy United States

Maria Grazia De Simoni Italy

Michelle L. Block

3.7k ×0.5

NEURO

2.4k ×0.7

2.2k ×0.8

CMN

543 ×0.2

HTM

1.3k ×0.5

PHYSI

Citations per year, relative to Michelle L. Block Michelle L. Block (= 1×) peers Maria Grazia De Simoni

Countries citing papers authored by Michelle L. Block

Since Specialization

Citations

This map shows the geographic impact of Michelle L. Block's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michelle L. Block with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michelle L. Block more than expected).

Fields of papers citing papers by Michelle L. Block

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michelle L. Block. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michelle L. Block. The network helps show where Michelle L. Block may publish in the future.

Co-authorship network of co-authors of Michelle L. Block

This figure shows the co-authorship network connecting the top 25 collaborators of Michelle L. Block. A scholar is included among the top collaborators of Michelle L. Block based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michelle L. Block. Michelle L. Block is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Garza-Lombó, Carla, et al.. (2024). Peripheral HMGB1 is linked to O₃ pathology of disease‐associated astrocytes and amyloid. Alzheimer s & Dementia. 20(5). 3551–3566. 8 indexed citations

Garza-Lombó, Carla, et al.. (2021). Circulating HMGB1 is elevated in veterans with Gulf War Illness and triggers the persistent pro-inflammatory microglia phenotype in male C57Bl/6J mice. Translational Psychiatry. 11(1). 390–390. 10 indexed citations

Taetzsch, Thomas, et al.. (2019). Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain. Journal of Neuroinflammation. 16(1). 60–60. 14 indexed citations

Dallas, Shannon, Michelle L. Block, Deborah Thompson, et al.. (2013). Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment. Journal of Neuroinflammation. 10(1). 58–58. 4 indexed citations

Surace, Michael & Michelle L. Block. (2012). Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors. Cellular and Molecular Life Sciences. 69(14). 2409–2427. 115 indexed citations

Lull, Melinda E., Shannon Levesque, Michael Surace, & Michelle L. Block. (2011). Chronic Apocynin Treatment Attenuates Beta Amyloid Plaque Size and Microglial Number in hAPP(751)SL Mice. PLoS ONE. 6(5). e20153–e20153. 46 indexed citations

Levesque, Shannon, Thomas Taetzsch, Melinda E. Lull, et al.. (2011). Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity. Environmental Health Perspectives. 119(8). 1149–1155. 293 indexed citations

Hahn, Yun K., et al.. (2010). β‐Chemokine production by neural and glial progenitor cells is enhanced by HIV‐1 Tat: effects on microglial migration. Journal of Neurochemistry. 114(1). 97–109. 36 indexed citations

Levesque, Shannon, Belinda Wilson, Shannon Dallas, et al.. (2010). Reactive microgliosis: extracellular μ-calpain and microglia-mediated dopaminergic neurotoxicity. Brain. 133(3). 808–821. 89 indexed citations

10.

Block, Michelle L. & Lilian Calderón‐Garcidueñas. (2009). Air pollution: mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences. 32(9). 506–516. 1187 indexed citations breakdown →

11.

Hu, Xiaoming, Dan Zhang, Hao Pang, et al.. (2008). Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease. The Journal of Immunology. 181(10). 7194–7204. 107 indexed citations

12.

Block, Michelle L.. (2008). NADPH oxidase as a therapeutic target in Alzheimer's disease. BMC Neuroscience. 9(S2). S8–S8. 176 indexed citations

13.

MohanKumar, Sheba M.J., Arezoo Campbell, Michelle L. Block, & Bellina Veronesi. (2008). Particulate matter, oxidative stress and neurotoxicity. NeuroToxicology. 29(3). 479–488. 167 indexed citations

14.

Qiao, Aimin, Ziqing Wang, J. Shawn Goodwin, et al.. (2008). Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model. Journal of Neuroscience. 28(45). 11622–11634. 209 indexed citations

15.

Yang, Sufen, Dan Zhang, Zhengqin Yang, et al.. (2008). Curcumin Protects Dopaminergic Neuron Against LPS Induced Neurotoxicity in Primary Rat Neuron/Glia Culture. Neurochemical Research. 33(10). 2044–2053. 79 indexed citations

16.

Pei, Zhong, Hao Pang, Qian Li, et al.. (2007). MAC1 mediates LPS‐induced production of superoxide by microglia: The role of pattern recognition receptors in dopaminergic neurotoxicity. Glia. 55(13). 1362–1373. 83 indexed citations

17.

Block, Michelle L., Luigi Zecca, & Jau‐Shyong Hong. (2006). Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature reviews. Neuroscience. 8(1). 57–69. 3328 indexed citations breakdown →

18.

Li, Qian, Michelle L. Block, Sung‐Jen Wei, et al.. (2006). Interleukin-10 Protects Lipopolysaccharide-Induced Neurotoxicity in Primary Midbrain Cultures by Inhibiting the Function of NADPH Oxidase. Journal of Pharmacology and Experimental Therapeutics. 319(1). 44–52. 94 indexed citations

19.

Zhang, Wei, Jau‐Shyong Hong, Hyoung‐Chun Kim, Wanqin Zhang, & Michelle L. Block. (2004). Morphinan Neuroprotection: New Insight into the Therapy of Neurodegeneration. PubMed. 16(4). 271–302. 10 indexed citations

20.

Granger, Douglas A., Kathryn E. Hood, Sandra C. Ikeda, Cheryl Reed, & Michelle L. Block. (1996). Neonatal Endotoxin Exposure Alters the Development of Social Behavior and the Hypothalamic–Pituitary–Adrenal Axis in Selectively Bred Mice. Brain Behavior and Immunity. 10(3). 249–259. 39 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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