Michel Chrétien

27.6k citations

483 papers · 22.8k indexed · 5 hit papers · h-index 80

Molecular Biology top 0.2%
Cellular and Molecular Neuroscience top 0.2%
Surgery top 0.5%
Cell Biology top 0.1%
Endocrinology, Diabetes and Metabolism top 0.2%

Co-authors: Nabil G. Seidah Suzanne Benjannet Majambu Mbikay Claude Lazure Robert Day Ajoy Basak Josée Hamelin M. Marcinkiewicz
Topics: Receptor Mechanisms and Signaling (98 papers)Neuropeptides and Animal Physiology (96 papers)Cellular transport and secretion (66 papers)
Cited by: Endocrine and Autonomic Systems Cell Biology Cellular and Molecular Neuroscience
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: Canada United States France

In The Last Decade

Michel Chrétien

478 papers receiving 21.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation

2003 953 citations Nabil G. Seidah, Suzanne Benjannet et al. profile →
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides1Published on the World Wide Web on 17 August 1999.1

1999 641 citations Nabil G. Seidah, Michel Chrétien Brain Research profile →
NARC-1/PCSK9 and Its Natural Mutants

2004 532 citations Suzanne Benjannet, Janice Mayne et al. Journal of Biological Chemistry profile →
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.

1991 522 citations Suzanne Benjannet, Normand Rondeau et al. profile →
PCSK9

2014 449 citations Nabil G. Seidah, Michel Chrétien et al. profile →

Peers

Countries citing papers authored by Michel Chrétien

Since Specialization

Citations

This map shows the geographic impact of Michel Chrétien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michel Chrétien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michel Chrétien more than expected).

Fields of papers citing papers by Michel Chrétien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michel Chrétien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michel Chrétien. The network helps show where Michel Chrétien may publish in the future.

Co-authorship network of co-authors of Michel Chrétien

This figure shows the co-authorship network connecting the top 25 collaborators of Michel Chrétien. A scholar is included among the top collaborators of Michel Chrétien based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michel Chrétien. Michel Chrétien is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface‐expression of LDLR and CD36 and NLRP3 inflammasome 2021 ·Physiological Reports ·(unknown),(unknown),(unknown),(unknown),Aurèle Besse‐Patin,Annie Demers,Martin Wabitsch,Michel Chrétien,Gaétan Mayer,Jennifer L. Estall,Maya Saleh,May Faraj	16
2	The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury 2020 ·Journal of Clinical Investigation ·Paul Lebeau,Hanny Wassef,Jae Hyun Byun,Khrystyna Platko,Brandon Ason,Simon Jackson,(unknown),Susan Shetterly,William G. Richards,Ali Al‐Hashimi,(unknown),Majambu Mbikay,Annik Prat,An Tang,Guillaume Paré,Renata Pasqualini,Nabil G. Seidah,Wadih Arap,Michel Chrétien,Richard C. Austin	30
3	White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity 2020 ·Obesity ·(unknown),(unknown),(unknown),Hanny Wassef,Emmanuelle Loizon,(unknown),Hubert Vidal,Gaétan Mayer,Michel Chrétien,May Faraj	19
4	How the Prohormone Theory Solved Two Important Controversies in Hormonal and Neural Peptide Biosynthesis 2013 ·Frontiers in Endocrinology ·Michel Chrétien	11
5	Ethnic Differences in the Frequency of the Cardioprotective C679X PCSK9 Mutation in a West African Population 2008 ·Genetic Testing ·Francine Sirois,Elias Gbeha,Ambaliou Sanni,Michel Chrétien,Damian Labuda,Majambu Mbikay	13
6	Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7 2008 ·Gut ·Nathalie Scamuffa,Amit Basak,Claude Lalou,(unknown),Jadwiga Marcinkiewicz,Géraldine Siegfried,Michel Chrétien,Fabien Calvo,Nabil G. Seidah,Abdel‐Majid Khatib	27
7	Inhibition of Chikungunya Virus Infection in Cultured Human Muscle Cells by Furin Inhibitors 2008 ·Journal of Biological Chemistry ·Simona Ozden,Marianne Lucas‐Hourani,Pierre‐Emmanuel Ceccaldi,Ajoy Basak,(unknown),Suzanne Benjannet,Josée Hamelin,Yves Jacob,Kamel Mamchaoui,Vincent Mouly,Philippe Desprès,Antoine Gessain,Gillian Butler‐Browne,Michel Chrétien,Frédéric Tangy,Pierre‐Olivier Vidalain,Nabil G. Seidah	110
8	A targeted deletion/insertion in the mouse Pcsk1 locus is associated with homozygous embryo preimplantation lethality, mutant allele preferential transmission and heterozygous female susceptibility to dietary fat 2007 ·Developmental Biology ·Majambu Mbikay,(unknown),Francine Sirois,Younès Anini,Janice Mayne,Nabil G. Seidah,Michel Chrétien	30
9	Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides 2001 ·Biochemical Journal ·Ajoy Basak,Mei Zhong,Jon Scott Munzer,Michel Chrétien,Nabil G. Seidah	90
10	The production of the ostrich NH2-terminal POMC fragment requires cleavage at a unique signal peptidase site 1993 ·Peptides ·Ryno J. Naudé,Derek Litthauer,Willem Oelofsen,Michel Chrétien,Claude Lazure	10
11	Expression and Sorting of Rat Plasma Kallikrein in POMC-Producing AtT-20 Cells 1991 ·DNA and Cell Biology ·Nicole Sawyer,Normand Rondeau,Michel Chrétien,Nabil G. Seidah	7
12	Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2 1991 ·FEBS Letters ·Luc Paquet,Normand Rondeau,Nabil G. Seidah,Claude Lazure,Michel Chrétien,Majambu Mbikay	23
13	Cloning and Primary Sequence of a Mouse Candidate Prohormone Convertase PC1 Homologous to PC2, Furin, and Kex2: Distinct Chromosomal Localization and Messenger RNA Distribution in Brain and Pituitary Compared to PC2 1991 ·Molecular Endocrinology ·Nabil G. Seidah,M. Marcinkiewicz,Suzanne Benjannet,Laurie Gaspar,(unknown),Marie‐Geneviève Mattéi,Claude Lazure,Majambu Mbikay,Michel Chrétien	421
14	The cDNA Structure of Rat Plasma Kallikrein 1989 ·DNA ·Nabil G. Seidah,(unknown),Majambu Mbikay,Josée Hamelin,Georges Lutfalla,François Rougeon,Claude Lazure,Michel Chrétien	18
15	Molecular Cloning and Sequence of the cDNA for a 94-Amino-Acid Seminal Plasma Protein Secreted by the Human Prostate 1987 ·DNA ·Majambu Mbikay,Serge Nolet,Sylvie Fournier,Suzanne Benjannet,Pierre Chapdelaine,Gilles Paradis,Jean Dubé,(unknown),Claude Lazure,Nabil G. Seidah,Michel Chrétien	61
16	The pituitary polypetide “7B2” is associated with LH/FSH and TSH cells and is localized within secretory vesicles 1987 ·Cell and Tissue Research ·M. Marcinkiewicz,Suzanne Benjannet,Nabil G. Seidah,M. Cantin,Michel Chrétien	46
17	Light and electron microscopic immunocytochemistry of β-endorphin/β-LPH-like immunoreactive neurons in the arcuate nucleus and surrounding areas of the rat hypothalamus 1985 ·Brain Research ·Csaba Leranth,Tim Williams,J. Hámori,Michel Chrétien	9
18	Structure and maturation process of pro-opiomelanocortin: a model for other neuropeptides. 1980 ·PubMed ·Michel Chrétien,Françis Gossard,Philippe Crine,Christina Gianoulakis,Nabil G. Seidah	2
19	Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland 1977 ·Endocrinology ·G. Pelletier,Rachel Leclerc,Fernand Labrie,James E. Côté,Michel Chrétien,M. Lis	169
20	Modification of Cunningham's method for the detection of proteases in tissue sections. 1975 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Catherine Michel,Michel Chrétien	4

About Michel Chrétien

Michel Chrétien is a scholar working on Endocrine and Autonomic Systems, Cellular and Molecular Neuroscience and Endocrinology, Diabetes and Metabolism, having authored 483 papers that have together received 22.8k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (98 papers), Neuropeptides and Animal Physiology (96 papers) and Cellular transport and secretion (66 papers). The work is most often cited by research in Endocrine and Autonomic Systems (2.1k citations), Cell Biology (4.5k citations) and Cellular and Molecular Neuroscience (5.0k citations). Michel Chrétien has collaborated with scholars based in Canada, United States and France. Frequent co-authors include Nabil G. Seidah, Suzanne Benjannet, Majambu Mbikay, Claude Lazure, Robert Day, Ajoy Basak, Josée Hamelin, M. Marcinkiewicz, Jadwiga Marcinkiewicz and Annik Prat. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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