Michael D. Waterfield

38.3k citations

187 papers · 32.3k indexed · 21 hit papers · h-index 80

Impact in

Cell Biology top 0.05%
- Cellular transport and secretion
Molecular Biology top 0.05%
- Protein Kinase Regulation and GTPase Signaling
- PI3K/AKT/mTOR signaling in cancer
- Glycosylation and Glycoproteins Research

Papers in

Cell Biology 41
- Cellular transport and secretion 26
Molecular Biology 139
- Protein Kinase Regulation and GTPase Signaling 53
- PI3K/AKT/mTOR signaling in cancer 30
- Glycosylation and Glycoproteins Research 22

Co-authors: Bart Vanhaesebroeck Julian Downward Peter J. Parker Paul Stroobant Joseph Schlessinger Nigel Whittle Sally J. Leevers E. L. V. Mayes
Journals: Journal of Biological Chemistry (25 papers)Biochemical Journal (13 papers)Nature (12 papers)The EMBO Journal (11 papers)Proceedings of the National Academy of Sciences (9 papers)
Partner nations: United Kingdom United States Belgium

In The Last Decade

Michael D. Waterfield

187 papers receiving 30.7k citations

Hit Papers

15 papers align trajectories log scale

Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice 2002 · 761 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Science
2001 Annual Review of Cell and Developmental Biology
2001 Annual Review of Biochemistry
1999 Experimental Cell Research
1999 Current Opinion in Cell Biology
1999 Nature Cell Biology
1996 Molecular and Cellular Biology
1995 Science
1993 Science
1988 Nature
1988 PubMed
1986 Science
1986 Science
1986 Science
1985 Nature
1985 Proceedings of the National Academy of Sciences
1984 Nature
1984 Nature
1984 Nature
1983 Nature
1982 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Michael D. Waterfield

Since Specialization

Citations

This map shows the geographic impact of Michael D. Waterfield's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael D. Waterfield with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael D. Waterfield more than expected).

Fields of papers citing papers by Michael D. Waterfield

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael D. Waterfield. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael D. Waterfield. The network helps show where Michael D. Waterfield may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael D. Waterfield, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael D. Waterfield Line = papers co-authored together Michael D. Waterfield links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	A selective PIKfyve inhibitor blocks PtdIns(3,5)P ₂ production and disrupts endomembrane transport and retroviral budding EMBO Reports ·Harold B.J. Jefferies, Frank T. Cooke, Parmjit Jat, Christine Boucheron, Tomonobu Koizumi, Masahiko Hayakawa, Hiroyuki Kaizawa, Takahide Ohishi, Paul Workman, Michael D. Waterfield, Peter J. Parker	2008	228
2	Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110α inhibitors Bioorganic & Medicinal Chemistry ·Masahiko Hayakawa, Kenichi Kawaguchi, Hiroyuki Kaizawa, Tomonobu Koizumi, Takahide Ohishi, Mayumi Yamano, Minoru Okada, Mitsuaki Ohta, Shin‐ichi Tsukamoto, Florence I. Raynaud, Peter J. Parker, Paul Workman, Michael D. Waterfield	2007	109
3	A parallel proteomic and metabolomic analysis of the hydrogen peroxide‐ and Sty1p‐dependent stress response in *Schizosaccharomyces pombe* PROTEOMICS ·Mark C. Willingham, John Sinclair, Amna Butt, Yuen‐Li Chung, Jessica L. Worthington, Caroline R.M. Wilkinson, John R. Griffiths, Nic Jones, Michael D. Waterfield, John F. Timms	2006	60
4	Cellular responses to ErbB-2 overexpression in human mammary luminal epithelial cells: comparison of mRNA and protein expression British Journal of Cancer ·S. L. White, Severine Gharbi, Mariana Fianco Bertani, H-L Chan, Michael D. Waterfield, John F. Timms	2004	39
5	Targeted Expression of the Class II Phosphoinositide 3-Kinase in Drosophila melanogaster Reveals Lipid Kinase-Dependent Effects on Patterning and Interactions with Receptor Signaling Pathways Molecular and Cellular Biology ·Lindsay K. MacDougall, Mary Elizabeth Gagou, Sally J. Leevers, Ernst Hafen, Michael D. Waterfield	2003	24
6	Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice Science ·Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot, Helen Priddle, Sara Sancho, Emma Peskett, Wayne Pearce, Stephen Meek, Ashreena Salpekar, Michael D. Waterfield, Andrew J. H. Smith, Bart Vanhaesebroeck Hit paper breakdown →	2002	761
7	Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells Oncogene ·John F. Timms, S. L. White, Michael J. O’Hare, Michael D. Waterfield	2002	56
8	Differential Proteome Analysis of Replicative Senescence in Rat Embryo Fibroblasts Molecular & Cellular Proteomics ·Silvia Benvenuti, Rainer Cramer, Christopher C. Quinn, Jim Bruce, Marketa Zvelebil, S. Corless, Jacquelyn Bond, Alice Yang, Susan Hockfield, Alma L. Burlingame, Michael D. Waterfield, Parmjit Jat	2002	39
9	Class II Phosphoinositide 3-Kinases Are Downstream Targets of Activated Polypeptide Growth Factor Receptors Molecular and Cellular Biology ·Alexandre Arcaro, Marketa Zvelebil, Christian Wallasch, Axel Ullrich, Michael D. Waterfield, Jan Domin	2000	136
10	The SH3 and BH Domains of the p85α Adapter Subunit Play a Critical Role in Regulating Class Ia Phosphoinositide 3-Kinase Function PubMed ·Caroline A. Beeton, P. Das, Michael D. Waterfield, Peter R. Shepherd	1999	18
11	Signaling by Distinct Classes of Phosphoinositide 3-Kinases Experimental Cell Research ·Bart Vanhaesebroeck, Michael D. Waterfield Hit paper breakdown →	1999	729
12	Binding of a Diphosphotyrosine-containing Peptide That Mimics Activated Platelet-derived Growth Factor Receptor β Induces Oligomerization of Phosphatidylinositol 3-Kinase Journal of Biological Chemistry ·Meredith J. Layton, Ailsa G. Harpur, George Panayotou, Philippe I. H. Bastiaens, Michael D. Waterfield	1998	34
13	Binding to the Platelet-derived Growth Factor Receptor Transiently Activates the p85α-p110α Phosphoinositide 3-Kinase Complex in Vivo Journal of Biological Chemistry ·Jan Domin, Ritu Dhand, Michael D. Waterfield	1996	33
14	Molecular Cloning of p125Nap1, a Protein That Associates with an SH3 Domain of Nck Biochemical and Biophysical Research Communications ·Tadahiro Kitamura, Yukari Kitamura, Kazuyoshi, Nicholas F. Totty, Ivan Gout, Kenta Hara, Michael D. Waterfield, Motoyoshi Sakaue, Wataru Ogawa, Masato Kasuga	1996	55
15	Ras-independent and Wortmannin-sensitive Activation of Glycogen Synthase by Insulin in Chinese Hamster Ovary Cells Journal of Biological Chemistry ·Hiroshi Sakaue, Kenta Hara, Tetsuya Noguchi, Takashi Matozaki, Kei Kotani, Wataru Ogawa, Kazuyoshi Yonezawa, Masato Kasuga, Michael D. Waterfield	1995	64
16	Interactions Between SH2 Domains and Tyrosine-Phosphorylated Platelet-Derived Growth Factor β-receptor Sequences: Analysis of Kinetic Parameters by a Novel Biosensor-Based Approach Molecular and Cellular Biology ·George Panayotou, G Gish, Peter End, O Truong, Ivan Gout, Ritu Dhand, Michael Fry, I. Hiles, Tony Pawson, Michael D. Waterfield	1993	31
17	Phosphatidyl-inositol 3-kinase: a key enzyme in diverse signalling processes Trends in Cell Biology ·George Panayotou, Michael D. Waterfield	1992	94
18	Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading. PubMed ·Mark S. Berger, Gottfried W. Locher, Susanne Saurer, William J. Gullick, Michael D. Waterfield, Bernd Groner, Nancy E. Hynes Hit paper breakdown →	1988	507
19	Loss of three major auto phosphorylation sites in the EGF receptor does not block the mitogenic action of EGF Journal of Cellular Physiology ·Stella Clark, Dorothy J. Cheng, J. Justin Hsuan, John D. Haley, Michael D. Waterfield	1988	18
20	The structure and function of the epidermal growth factor receptor studied by using antisynthetic peptide antibodies Proceedings of the Royal Society of London. Series B, Biological sciences ·William J. Gullick, Julian Downward, Peter J. Parker, Nigel Whittle, Richard Kris, Joseph Schlessinger, A. Ullrich, Michael D. Waterfield	1985	35

About Michael D. Waterfield

Michael D. Waterfield is a scholar working on Cell Biology, Molecular Biology, Immunology and Allergy, Radiology, Nuclear Medicine and Imaging and Oncology, having authored 187 papers that have together received 32.3k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (53 papers), Monoclonal and Polyclonal Antibodies Research (35 papers), PI3K/AKT/mTOR signaling in cancer (30 papers), Cellular transport and secretion (26 papers), Glycosylation and Glycoproteins Research (22 papers), HER2/EGFR in Cancer Research (14 papers), Advanced Proteomics Techniques and Applications (13 papers) and Cell Adhesion Molecules Research (11 papers). The work is most often cited by research in Cell Biology (5.2k citations), Molecular Biology (20.8k citations), Oncology (7.2k citations), Immunology and Allergy (1.4k citations) and Genetics (2.5k citations). Michael D. Waterfield has collaborated with scholars based in United Kingdom, United States and Belgium. Frequent co-authors include Bart Vanhaesebroeck, Julian Downward, Peter J. Parker, Paul Stroobant, Joseph Schlessinger, Nigel Whittle, Sally J. Leevers, E. L. V. Mayes, John F. Timms and Axel Ullrich. Their work appears in journals such as Journal of Biological Chemistry, Biochemical Journal, Nature, The EMBO Journal and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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