Wayne Pearce

5.0k citations

30 papers · 3.7k indexed · 1 hit paper · h-index 24

Impact in

Genetics top 1%
- Chronic Lymphocytic Leukemia Research
Immunology top 1%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Mast cells and histamine
- Immunodeficiency and Autoimmune Disorders

Papers in ⓘ

Immunology 9
- Immune Cell Function and Interaction 4
- Phagocytosis and Immune Regulation 3
- T-cell and B-cell Immunology 3
Genetics 4
- Coagulation, Bradykinin, Polyphosphates, and Angioedema 3

Co-authors: Bart Vanhaesebroeck (25 shared papers)Klaus Okkenhaug (7 shared papers)Sara Sancho (4 shared papers)Stephen Meek (3 shared papers)Emma Peskett (3 shared papers)Andrew J. H. Smith (2 shared papers)Antonio Bilancio (4 shared papers)Ashreena Salpekar (2 shared papers)
Journals: Nature (4 papers)The Journal of Immunology (3 papers)Proceedings of the National Academy of Sciences (3 papers)Biochemical Journal (2 papers)Blood (1 paper)
Partner nations: United Kingdom Switzerland France

In The Last Decade

Wayne Pearce

28 papers receiving 3.7k citations

Hit Papers

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Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice 2002 · 761 citations

Peers

Countries citing papers authored by Wayne Pearce

Since Specialization

Citations

This map shows the geographic impact of Wayne Pearce's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wayne Pearce with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wayne Pearce more than expected).

Fields of papers citing papers by Wayne Pearce

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wayne Pearce. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wayne Pearce. The network helps show where Wayne Pearce may publish in the future.

Co-authors

The 25 scholars most cited alongside Wayne Pearce, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wayne Pearce Line = papers co-authored together Wayne Pearce links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 30 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice Science ·Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot, Helen Priddle, Sara Sancho, Emma Peskett, Wayne Pearce, Stephen Meek, Ashreena Salpekar, Michael D. Waterfield, Andrew J. H. Smith, Bart Vanhaesebroeck Hit paper breakdown →	2002	761
2	Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration Nature ·Mariona Graupera, Julie Guillermet‐Guibert, Lazaros C. Foukas, Li‐Kun Phng, Robert J. Cain, Ashreena Salpekar, Wayne Pearce, Stephen Meek, Jaime Millán, Pedro R. Cutillas, Andrew J. H. Smith, Anne J. Ridley, Christiana Ruhrberg, Holger Gerhardt, Bart Vanhaesebroeck	2008	414
3	Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer Nature ·Khaled Ali, Dalya R. Soond, Roberto Piñeiro, Thorsten Hagemann, Wayne Pearce, Ee Lyn Lim, Hicham Bouabe, Cheryl L. Scudamore, Timothy C. Hancox, Heather Maecker, Lori S. Friedman, Martin Turner, Klaus Okkenhaug, Bart Vanhaesebroeck	2014	397
4	Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation Nature ·Lazaros C. Foukas, Marc Claret, Wayne Pearce, Klaus Okkenhaug, Stephen Meek, Emma Peskett, Sara Sancho, Andrew J. H. Smith, Dominic J. Withers, Bart Vanhaesebroeck	2006	369
5	Essential role for the p110δ phosphoinositide 3-kinase in the allergic response Nature ·Khaled Ali, Antonio Bilancio, Matthew J. Thomas, Wayne Pearce, Alasdair M. Gilfillan, Christine Tkaczyk, Nicolas Kuehn, Alexander Gray, June Giddings, Emma Peskett, Roy Fox, Ian Bruce, Christoph Walker, Carol Sawyer, Klaus Okkenhaug, Peter M. Finan, Bart Vanhaesebroeck	2004	332
6	Cutting Edge: The Phosphoinositide 3-Kinase p110δ Is Critical for the Function of CD4+CD25+Foxp3+ Regulatory T Cells The Journal of Immunology ·Daniel T. Patton, Oliver A. Garden, Wayne Pearce, Louise E. Clough, Clare R Monk, Eva Leung, Wendy C. Rowan, Sara Sancho, Lucy S. K. Walker, Bart Vanhaesebroeck, Klaus Okkenhaug	2006	249
7	The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock Nature Immunology ·Ezra Aksoy, Salma Taboubi, David Torres, Sandrine Delbauve, Abderrahman Hachani, Maria A. Whitehead, Wayne Pearce, Inma M. Berenjeno, Gemma Nock, Alain Filloux, Rudi Beyaert, Véronique Flamand, Bart Vanhaesebroeck	2012	148
8	Isoform-Specific Functions of Phosphoinositide 3-Kinases: p110δ but Not p110γ Promotes Optimal Allergic Responses In Vivo The Journal of Immunology ·Khaled Ali, Montserrat Camps, Wayne Pearce, Hong Ji, Thomas Rückle, Nicolas Kuehn, Christian Pasquali, Christian Chabert, Christian Rommel, Bart Vanhaesebroeck	2008	99
9	Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation Blood ·Hong Ji, Felix Rintelen, Caroline Waltzinger, Dominique Bertschy Meier, Antonio Bilancio, Wayne Pearce, Emilio Hirsch, Matthias P. Wymann, Thomas Rückle, Montserrat Camps, Bart Vanhaesebroeck, Klaus Okkenhaug, Christian Rommel	2007	98
10	Control of Axonal Growth and Regeneration of Sensory Neurons by the p110δ PI 3-Kinase PLoS ONE ·Britta J. Eickholt, Aminul I. Ahmed, Meirion Davies, Evangelia A. Papakonstanti, Wayne Pearce, Michelle L. Starkey, Antonio Bilancio, Anna C. Need, Andrew J. H. Smith, Susan Hall, Frank P.T. Hamers, Karl-Peter Giese, Elizabeth J. Bradbury, Bart Vanhaesebroeck	2007	96
11	Antigen presentation by macrophages is enhanced by the uptake of necrotic, but not apoptotic, cells Clinical & Experimental Immunology ·Robert N. Barker, L-P Erwig, Kathryn Hill, Anne Devine, Wayne Pearce, Andrew J. Rees	2002	82
12	Long‐term p110α PI3K inactivation exerts a beneficial effect on metabolism EMBO Molecular Medicine ·Lazaros C. Foukas, Benoît Bilanges, Lucia Bettedi, Wayne Pearce, Khaled Ali, Sara Sancho, Dominic J. Withers, Bart Vanhaesebroeck	2013	73
13	Macrophages Transfected with Adenovirus to Express IL-4 Reduce Inflammation in Experimental Glomerulonephritis The Journal of Immunology ·David Kluth, Clare V. Ainslie, Wayne Pearce, Sian Finlay, Daniel Clarke, Ignacio Anegón, Andrew J. Rees	2001	69
14	Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity Cell Reports ·Samira Alliouachene, Benoît Bilanges, Gaëtan Chicanne, Karen E. Anderson, Wayne Pearce, Khaled Ali, Colin Valet, York Posor, Pei Ching Low, Claire Chaussade, Cheryl L. Scudamore, Rachel S. Salamon, Jonathan Backer, Len Stephens, Phillip T. Hawkins, Bernard Payrastre, Bart Vanhaesebroeck	2015	62
15	Airway inflammation: chemokine‐induced neutrophilia and the class I phosphoinositide 3‐kinases European Journal of Immunology ·Matthew J. Thomas, Alexandra Smith, Denise Head, Laura Milne, Andrew Nicholls, Wayne Pearce, Bart Vanhaesebroeck, Matthias P. Wymann, Emilio Hirsch, Alexandre Trifilieff, Christoph Walker, Peter M. Finan, John Westwick	2005	57
16	Differential Effects of Necrotic or Apoptotic Cell Uptake on Antigen Presentation by Macrophages Pathobiology ·Robert N. Barker, Lars-Peter Erwig, Wayne Pearce, Anne Devine, Andrew J. Rees	1999	57
17	Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis The Journal of Experimental Medicine ·Adriana Soler, Helena Serra, Wayne Pearce, Ana Angulo‐Urarte, Julie Guillermet‐Guibert, Lori S. Friedman, Francesc Viñals, Holger Gerhardt, Oriol Casanovas, Mariona Graupera, Bart Vanhaesebroeck	2013	56
18	Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor Biochemical Journal ·Inma M. Berenjeno, Julie Guillermet‐Guibert, Wayne Pearce, Alexander Gray, Stewart Fleming, Bart Vanhaesebroeck	2011	54
19	Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner Proceedings of the National Academy of Sciences ·Ralitsa R. Madsen, Rachel Knox, Wayne Pearce, Saioa López, Betania Mahler‐Araujo, Nicholas McGranahan, Bart Vanhaesebroeck, Robert K. Semple	2019	42
20	Role of the p110δ PI 3-kinase in integrin and ITAM receptor signalling in platelets Platelets ·Yotis A. Senis, Ben Atkinson, Andrew C. Pearce, Peter Wonerow, Jocelyn M. Auger, Klaus Okkenhaug, Wayne Pearce, Elena Vigorito, Bart Vanhaesebroeck, Martin Turner, Steve P. Watson	2005	40

About Wayne Pearce

Wayne Pearce is a scholar working on Immunology, Genetics, Cancer Research, Molecular Biology and Oncology, having authored 30 papers that have together received 3.7k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (9 papers), Immune Cell Function and Interaction (4 papers), Metabolism, Diabetes, and Cancer (3 papers), Phagocytosis and Immune Regulation (3 papers), Renal and related cancers (3 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (3 papers), T-cell and B-cell Immunology (3 papers) and Cancer, Hypoxia, and Metabolism (3 papers). The work is most often cited by research in Genetics (815 citations), Immunology (1.6k citations), Molecular Biology (2.1k citations), Oncology (808 citations) and Aging (46 citations). Wayne Pearce has collaborated with scholars based in United Kingdom, Switzerland and France. Frequent co-authors include Bart Vanhaesebroeck, Klaus Okkenhaug, Sara Sancho, Stephen Meek, Emma Peskett, Andrew J. H. Smith, Antonio Bilancio, Ashreena Salpekar, Lazaros C. Foukas and Khaled Ali. Their work appears in journals such as Nature, The Journal of Immunology, Proceedings of the National Academy of Sciences, Biochemical Journal and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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