Wayne Pearce

5.0k total citations · 1 hit paper
30 papers, 3.7k citations indexed

About

Wayne Pearce is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Wayne Pearce has authored 30 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 9 papers in Immunology and 6 papers in Oncology. Recurrent topics in Wayne Pearce's work include PI3K/AKT/mTOR signaling in cancer (9 papers), Immune Cell Function and Interaction (4 papers) and Cancer, Hypoxia, and Metabolism (3 papers). Wayne Pearce is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (9 papers), Immune Cell Function and Interaction (4 papers) and Cancer, Hypoxia, and Metabolism (3 papers). Wayne Pearce collaborates with scholars based in United Kingdom, France and Switzerland. Wayne Pearce's co-authors include Bart Vanhaesebroeck, Klaus Okkenhaug, Sara Sancho, Stephen Meek, Emma Peskett, Andrew J. H. Smith, Antonio Bilancio, Ashreena Salpekar, Lazaros C. Foukas and Khaled Ali and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Wayne Pearce

28 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice

2002 761 citations Klaus Okkenhaug, Antonio Bilancio et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Wayne Pearce United Kingdom	24	2.1k	1.6k	815	808	294	30	3.7k
Roland P. Piekorz Germany	33	1.6k 0.8×	1.1k 0.7×	450 0.6×	1.0k 1.3×	223 0.8×	75	3.4k
Hong Ji China	21	1.8k 0.9×	1.9k 1.2×	383 0.5×	930 1.2×	172 0.6×	35	4.1k
Paul S. Changelian United States	27	1.7k 0.8×	1.6k 1.0×	402 0.5×	1.5k 1.8×	213 0.7×	39	4.4k
Rossella Paolini Italy	33	979 0.5×	1.9k 1.2×	315 0.4×	862 1.1×	281 1.0×	116	3.3k
Haihua Gu China	32	3.3k 1.6×	2.0k 1.3×	355 0.4×	1.2k 1.5×	138 0.5×	85	5.1k
Rebecca J. Chan United States	32	2.2k 1.1×	917 0.6×	349 0.4×	531 0.7×	167 0.6×	90	3.3k
Tilman Brummer Germany	35	2.9k 1.4×	897 0.6×	265 0.3×	1.2k 1.5×	362 1.2×	98	4.3k
Giovanna Tabellini Italy	37	2.2k 1.1×	1.2k 0.8×	246 0.3×	882 1.1×	188 0.6×	74	3.9k
Isabelle Dusanter‐Fourt France	38	1.9k 0.9×	1.3k 0.9×	706 0.9×	1.9k 2.4×	381 1.3×	83	4.8k
N. Shaun B. Thomas United Kingdom	30	1.9k 0.9×	778 0.5×	326 0.4×	735 0.9×	275 0.9×	56	3.1k

Countries citing papers authored by Wayne Pearce

Since Specialization

Citations

This map shows the geographic impact of Wayne Pearce's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wayne Pearce with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wayne Pearce more than expected).

Fields of papers citing papers by Wayne Pearce

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wayne Pearce. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wayne Pearce. The network helps show where Wayne Pearce may publish in the future.

Co-authorship network of co-authors of Wayne Pearce

This figure shows the co-authorship network connecting the top 25 collaborators of Wayne Pearce. A scholar is included among the top collaborators of Wayne Pearce based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wayne Pearce. Wayne Pearce is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Posor, York, Sarah E. Conduit, Wayne Pearce, et al.. (2025). Inactivation of PI3K-C2α deregulates cell death pathways and sensitizes to endotoxic shock. Proceedings of the National Academy of Sciences. 122(29). e2423358122–e2423358122.

Conduit, Sarah E., Wayne Pearce, Amandeep Bhamra, et al.. (2024). A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease. Nature Communications. 15(1). 7181–7181. 5 indexed citations

Madsen, Ralitsa R., Rachel Knox, Wayne Pearce, et al.. (2019). Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner. Proceedings of the National Academy of Sciences. 116(17). 8380–8389. 42 indexed citations

Alliouachene, Samira, Benoît Bilanges, Claire Chaussade, et al.. (2016). Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice. Diabetologia. 59(7). 1503–1512. 25 indexed citations

Guillermet‐Guibert, Julie, Lee B. Smith, Guillaume Halet, et al.. (2015). Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells. PLoS Genetics. 11(7). e1005304–e1005304. 40 indexed citations

Alliouachene, Samira, Benoît Bilanges, Gaëtan Chicanne, et al.. (2015). Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity. Cell Reports. 13(9). 1881–1894. 62 indexed citations

Ali, Khaled, Dalya R. Soond, Roberto Piñeiro, et al.. (2014). Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer. Nature. 510(7505). 407–411. 397 indexed citations

Pearce, Wayne, Ana Angulo‐Urarte, Julie Guillermet‐Guibert, et al.. (2013). Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis. The Journal of Experimental Medicine. 210(10). 1937–1945. 56 indexed citations

Graupera, Mariona, Julie Guillermet‐Guibert, Lazaros C. Foukas, et al.. (2008). Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration. Nature. 453(7195). 662–666. 414 indexed citations

10.

Ali, Khaled, Montserrat Camps, Wayne Pearce, et al.. (2008). Isoform-Specific Functions of Phosphoinositide 3-Kinases: p110δ but Not p110γ Promotes Optimal Allergic Responses In Vivo. The Journal of Immunology. 180(4). 2538–2544. 99 indexed citations

11.

Eickholt, Britta J., Aminul I. Ahmed, Meirion Davies, et al.. (2007). Control of Axonal Growth and Regeneration of Sensory Neurons by the p110δ PI 3-Kinase. PLoS ONE. 2(9). e869–e869. 96 indexed citations

12.

Patton, Daniel T., Oliver A. Garden, Wayne Pearce, et al.. (2006). Cutting Edge: The Phosphoinositide 3-Kinase p110δ Is Critical for the Function of CD4+CD25+Foxp3+ Regulatory T Cells. The Journal of Immunology. 177(10). 6598–6602. 249 indexed citations

13.

Foukas, Lazaros C., Marc Claret, Wayne Pearce, et al.. (2006). Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature. 441(7091). 366–370. 369 indexed citations

14.

Senis, Yotis A., Ben Atkinson, Andrew C. Pearce, et al.. (2005). Role of the p110δ PI 3-kinase in integrin and ITAM receptor signalling in platelets. Platelets. 16(3-4). 191–202. 40 indexed citations

15.

Thomas, Matthew J., Alexandra Smith, Laura Milne, et al.. (2005). Airway inflammation: chemokine‐induced neutrophilia and the class I phosphoinositide 3‐kinases. European Journal of Immunology. 35(4). 1283–1291. 57 indexed citations

16.

Ali, Khaled, Antonio Bilancio, Matthew J. Thomas, et al.. (2004). Essential role for the p110δ phosphoinositide 3-kinase in the allergic response. Nature. 431(7011). 1007–1011. 332 indexed citations

17.

Okkenhaug, Klaus, Antonio Bilancio, Géraldine Farjot, et al.. (2002). Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice. Science. 297(5583). 1031–1034. 761 indexed citations breakdown →

18.

Barker, Robert N., et al.. (2002). Antigen presentation by macrophages is enhanced by the uptake of necrotic, but not apoptotic, cells. Clinical & Experimental Immunology. 127(2). 220–225. 82 indexed citations

19.

Kluth, David, et al.. (2001). Macrophages Transfected with Adenovirus to Express IL-4 Reduce Inflammation in Experimental Glomerulonephritis. The Journal of Immunology. 166(7). 4728–4736. 69 indexed citations

20.

Barker, Robert N., et al.. (1999). Differential Effects of Necrotic or Apoptotic Cell Uptake on Antigen Presentation by Macrophages. Pathobiology. 67(5-6). 302–305. 57 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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